SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BNI'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2UZ2_A_ACTA1123_0 (XENAVIDIN)	2fhl	AVIDIN-RELATED PROTEIN 4/5 (Gallus gallus)	6 / 7	ASN A 12 LEU A 14 SER A 16 TYR A 33 THR A 35 VAL A 37	BNI A 501 (-3.4A) BNI A 501 ( 4.9A) BNI A 501 (-2.7A) BNI A 501 (-4.6A) BNI A 501 (-3.6A) BNI A 501 (-4.9A)	0.38A	2uz2A-2fhlA: 20.9	2uz2A-2fhlA: 56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2UZ2_A_ACTA1123_0 (XENAVIDIN)	2fhl	AVIDIN-RELATED PROTEIN 4/5 (Gallus gallus)	5 / 7	ASN A 116 LEU A 14 TYR A 33 THR A 35 VAL A 37	BNI A 501 (-3.3A) BNI A 501 ( 4.9A) BNI A 501 (-4.6A) BNI A 501 (-3.6A) BNI A 501 (-4.9A)	1.13A	2uz2A-2fhlA: 20.9	2uz2A-2fhlA: 56.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_C_CLMC221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2fhl	AVIDIN-RELATED PROTEIN 4/5 (Gallus gallus)	5 / 11	PHE A 77 PHE A 118 SER A 16 TYR A 33 VAL A 113	None None BNI A 501 (-2.7A) BNI A 501 (-4.6A) None	1.44A	3u9fA-2fhlA: 0.0 3u9fC-2fhlA: 0.0	3u9fA-2fhlA: 16.96 3u9fC-2fhlA: 16.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5LUR_A_STRA201_1 (AVIDIN)	2fhl	AVIDIN-RELATED PROTEIN 4/5 (Gallus gallus)	7 / 10	TYR A 33 TRP A 68 PHE A 70 THR A 75 PHE A 77 TRP A 95 ASN A 116	BNI A 501 (-4.6A) BNI A 501 (-3.6A) BNI A 501 ( 4.8A) BNI A 501 (-3.3A) None BNI A 501 (-3.2A) BNI A 501 (-3.3A)	0.34A	5lurA-2fhlA: 19.7	5lurA-2fhlA: 75.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5LUR_B_STRB201_1 (AVIDIN)	2fhl	AVIDIN-RELATED PROTEIN 4/5 (Gallus gallus)	7 / 11	TYR A 33 TRP A 68 PHE A 70 THR A 75 PHE A 77 TRP A 95 ASN A 116	BNI A 501 (-4.6A) BNI A 501 (-3.6A) BNI A 501 ( 4.8A) BNI A 501 (-3.3A) None BNI A 501 (-3.2A) BNI A 501 (-3.3A)	0.30A	5lurB-2fhlA: 19.6	5lurB-2fhlA: 75.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2UZ2_A_ACTA1123_0","XENAVIDIN","2fhl","AVIDIN-RELATED PROTEIN 4\/5","Gallus gallus",6,"ASN A  12;LEU A  14;SER A  16;TYR A  33;THR A  35;VAL A  37","BNI A 501 (-3.4A);BNI A 501 ( 4.9A);BNI A 501 (-2.7A);BNI A 501 (-4.6A);BNI A 501 (-3.6A);BNI A 501 (-4.9A)","0.38A","2uz2A-2fhlA:20.9",null],["2UZ2_A_ACTA1123_0","XENAVIDIN","2fhl","AVIDIN-RELATED PROTEIN 4\/5","Gallus gallus",5,"ASN A 116;LEU A  14;TYR A  33;THR A  35;VAL A  37","BNI A 501 (-3.3A);BNI A 501 ( 4.9A);BNI A 501 (-4.6A);BNI A 501 (-3.6A);BNI A 501 (-4.9A)","1.13A","2uz2A-2fhlA:20.9","2uz2A-2fhlA:56.56"],["3U9F_C_CLMC221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","2fhl","AVIDIN-RELATED PROTEIN 4\/5","Gallus gallus",5,"PHE A  77;PHE A 118;SER A  16;TYR A  33;VAL A 113","None;None;BNI A 501 (-2.7A);BNI A 501 (-4.6A);None","1.44A","3u9fA-2fhlA:0.0;3u9fC-2fhlA:0.0","2uz2A-2fhlA:56.56"],["5LUR_A_STRA201_1","AVIDIN","2fhl","AVIDIN-RELATED PROTEIN 4\/5","Gallus gallus",7,"TYR A  33;TRP A  68;PHE A  70;THR A  75;PHE A  77;TRP A  95;ASN A 116","BNI A 501 (-4.6A);BNI A 501 (-3.6A);BNI A 501 ( 4.8A);BNI A 501 (-3.3A);None;BNI A 501 (-3.2A);BNI A 501 (-3.3A)","0.34A","5lurA-2fhlA:19.7","3u9fA-2fhlA:16.96;3u9fC-2fhlA:16.96"],["5LUR_B_STRB201_1","AVIDIN","2fhl","AVIDIN-RELATED PROTEIN 4\/5","Gallus gallus",7,"TYR A  33;TRP A  68;PHE A  70;THR A  75;PHE A  77;TRP A  95;ASN A 116","BNI A 501 (-4.6A);BNI A 501 (-3.6A);BNI A 501 ( 4.8A);BNI A 501 (-3.3A);None;BNI A 501 (-3.2A);BNI A 501 (-3.3A)","0.30A","5lurB-2fhlA:19.6","5lurA-2fhlA:75.20"]]