SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BMX'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 4ivn TRANSCRIPTIONAL
REGULATOR
(Vibrio
vulnificus) 		5 / 9 ILE A 140
VAL A 141
GLY A 235
ALA A 236
SER A 104
 None
None
BMX  A1000 ( 4.7A)
None
None
 0.92A 4r21B-4ivnA:
undetectable		 4r21B-4ivnA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 4ivn TRANSCRIPTIONAL
REGULATOR
(Vibrio
vulnificus) 		4 / 6 SER A 239
ALA A 137
SER A 138
ALA A 236
 None
BMX  A1000 (-3.4A)
BMX  A1000 (-2.6A)
None
 0.83A 6bocA-4ivnA:
undetectable
6bocB-4ivnA:
undetectable
6bocC-4ivnA:
undetectable
6bocD-4ivnA:
undetectable		 6bocA-4ivnA:
5.98
6bocB-4ivnA:
5.98
6bocC-4ivnA:
5.98
6bocD-4ivnA:
5.98