SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BMF'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2X45_C_HSMC1161_1 (ALLERGEN ARG R 1) |
5c4q | BROMODOMAIN (Leishmaniadonovani) | 4 / 5 | VAL A 48TYR A 45VAL A 36ASP A 53 | NoneUNX A 203 ( 4.4A)BMF A 201 (-4.6A)None | 1.31A | 2x45C-5c4qA:undetectable | 2x45C-5c4qA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y00_B_Y00B601_2 (BETA-1 ADRENERGICRECEPTOR) |
5c4q | BROMODOMAIN (Leishmaniadonovani) | 3 / 3 | VAL A 47ASN A 87TRP A 93 | NoneBMF A 201 (-2.8A)BMF A 201 (-3.5A) | 1.03A | 2y00B-5c4qA:undetectable | 2y00B-5c4qA:15.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3U5K_A_08JA1_1 (BROMODOMAIN-CONTAINING PROTEIN 4) |
5u9n | BROMO DOMAINCONTAINING PROTEIN (Cryptosporidiumparvum) | 4 / 8 | VAL A 332LEU A 338ASN A 413ILE A 422 | BMF A 501 (-4.2A)BMF A 501 ( 4.9A)BMF A 501 (-2.8A)BMF A 501 ( 4.4A) | 0.77A | 3u5kA-5u9nA:14.3 | 3u5kA-5u9nA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3U5K_B_08JB2_1 (BROMODOMAIN-CONTAINING PROTEIN 4) |
5u9n | BROMO DOMAINCONTAINING PROTEIN (Cryptosporidiumparvum) | 4 / 7 | VAL A 332LEU A 338ASN A 413ILE A 422 | BMF A 501 (-4.2A)BMF A 501 ( 4.9A)BMF A 501 (-2.8A)BMF A 501 ( 4.4A) | 0.78A | 3u5kB-5u9nA:14.2 | 3u5kB-5u9nA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3U5K_C_08JC3_1 (BROMODOMAIN-CONTAINING PROTEIN 4) |
5u9n | BROMO DOMAINCONTAINING PROTEIN (Cryptosporidiumparvum) | 4 / 8 | VAL A 332LEU A 338ASN A 413ILE A 422 | BMF A 501 (-4.2A)BMF A 501 ( 4.9A)BMF A 501 (-2.8A)BMF A 501 ( 4.4A) | 0.80A | 3u5kC-5u9nA:14.3 | 3u5kC-5u9nA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A9J_A_TYLA1188_1 (BROMODOMAINCONTAINING 2) |
5u9n | BROMO DOMAINCONTAINING PROTEIN (Cryptosporidiumparvum) | 4 / 5 | VAL A 332LEU A 338ASN A 413ILE A 422 | BMF A 501 (-4.2A)BMF A 501 ( 4.9A)BMF A 501 (-2.8A)BMF A 501 ( 4.4A) | 0.84A | 4a9jA-5u9nA:15.4 | 4a9jA-5u9nA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A9J_B_TYLB1187_1 (BROMODOMAINCONTAINING 2) |
5u9n | BROMO DOMAINCONTAINING PROTEIN (Cryptosporidiumparvum) | 4 / 5 | VAL A 332LEU A 338ASN A 413ILE A 422 | BMF A 501 (-4.2A)BMF A 501 ( 4.9A)BMF A 501 (-2.8A)BMF A 501 ( 4.4A) | 0.81A | 4a9jB-5u9nA:15.7 | 4a9jB-5u9nA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A9J_C_TYLC1184_1 (BROMODOMAINCONTAINING 2) |
5u9n | BROMO DOMAINCONTAINING PROTEIN (Cryptosporidiumparvum) | 4 / 5 | VAL A 332LEU A 338ASN A 413ILE A 422 | BMF A 501 (-4.2A)BMF A 501 ( 4.9A)BMF A 501 (-2.8A)BMF A 501 ( 4.4A) | 0.77A | 4a9jC-5u9nA:15.2 | 4a9jC-5u9nA:20.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4Y03_A_SALA801_1 (PROTEIN POLYBROMO-1) |
5c4q | BROMODOMAIN (Leishmaniadonovani) | 4 / 7 | TYR A 44MET A 79ALA A 83ASN A 87 | BMF A 201 ( 4.9A)NoneBMF A 201 ( 4.1A)BMF A 201 (-2.8A) | 0.32A | 4y03A-5c4qA:13.3 | 4y03A-5c4qA:31.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5PBE_A_TYLA2001_1 (BROMODOMAIN ADJACENTTO ZINC FINGERDOMAIN PROTEIN 2B) |
5c4q | BROMODOMAIN (Leishmaniadonovani) | 4 / 6 | VAL A 36VAL A 41TYR A 44ASN A 87 | BMF A 201 (-4.6A)BMF A 201 (-4.2A)BMF A 201 ( 4.9A)BMF A 201 (-2.8A) | 0.92A | 5pbeA-5c4qA:15.2 | 5pbeA-5c4qA:29.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5PBE_A_TYLA2001_1 (BROMODOMAIN ADJACENTTO ZINC FINGERDOMAIN PROTEIN 2B) |
5u9n | BROMO DOMAINCONTAINING PROTEIN (Cryptosporidiumparvum) | 4 / 6 | VAL A 332TYR A 346ASN A 413ILE A 422 | BMF A 501 (-4.2A)NoneBMF A 501 (-2.8A)BMF A 501 ( 4.4A) | 0.65A | 5pbeA-5u9nA:15.3 | 5pbeA-5u9nA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Y1Y_A_HNQA201_1 (BROMODOMAIN-CONTAINING PROTEIN 4) |
5u9n | BROMO DOMAINCONTAINING PROTEIN (Cryptosporidiumparvum) | 5 / 8 | VAL A 332LEU A 338CYH A 409ASN A 413ILE A 422 | BMF A 501 (-4.2A)BMF A 501 ( 4.9A)BMF A 501 ( 3.8A)BMF A 501 (-2.8A)BMF A 501 ( 4.4A) | 0.77A | 5y1yA-5u9nA:14.2 | 5y1yA-5u9nA:24.18 |