SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BLR'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		5 / 12 PHE A  17
ASP A  81
ARG A  83
ARG A 132
TYR A 134
 BLR  A 200 (-3.6A)
None
None
BLR  A 200 (-3.5A)
None
 0.85A 2qm9A-4i3cA:
21.6		 2qm9A-4i3cA:
40.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		5 / 12 PHE A  17
THR A  65
ARG A  83
ARG A 132
TYR A 134
 BLR  A 200 (-3.6A)
BLR  A 200 ( 4.0A)
None
BLR  A 200 (-3.5A)
None
 0.90A 2qm9A-4i3cA:
21.6		 2qm9A-4i3cA:
40.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		6 / 12 PHE A  17
TYR A  20
THR A  65
ARG A  83
ARG A 132
TYR A 134
 BLR  A 200 (-3.6A)
None
BLR  A 200 ( 4.0A)
None
BLR  A 200 (-3.5A)
None
 0.87A 2qm9B-4i3cA:
22.0		 2qm9B-4i3cA:
40.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_1
(NEURAMINIDASE A)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		5 / 12 ILE A  24
ASP A  81
GLN A  57
ARG A 112
TYR A  99
 None
None
BLR  A 200 (-2.7A)
BLR  A 200 (-3.6A)
BLR  A 200 ( 4.4A)
 1.44A 2ya7A-4i3cA:
2.0		 2ya7A-4i3cA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_1
(NEURAMINIDASE A)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		5 / 12 ILE A  24
ASP A  81
PHE A  17
GLN A  57
ARG A 112
 None
None
BLR  A 200 (-3.6A)
BLR  A 200 (-2.7A)
BLR  A 200 (-3.6A)
 1.19A 2ya7A-4i3cA:
2.0		 2ya7A-4i3cA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_1
(NEURAMINIDASE A)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		5 / 12 ILE A  24
ASP A  81
GLN A  57
ARG A 112
TYR A  99
 None
None
BLR  A 200 (-2.7A)
BLR  A 200 (-3.6A)
BLR  A 200 ( 4.4A)
 1.45A 2ya7B-4i3cA:
undetectable		 2ya7B-4i3cA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_1
(NEURAMINIDASE A)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		5 / 12 ILE A  24
ASP A  81
GLN A  57
ARG A 112
TYR A  99
 None
None
BLR  A 200 (-2.7A)
BLR  A 200 (-3.6A)
BLR  A 200 ( 4.4A)
 1.45A 2ya7D-4i3cA:
2.4		 2ya7D-4i3cA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		4 / 7 TYR A 134
ARG A 112
PHE A  17
ILE A  11
 None
BLR  A 200 (-3.6A)
BLR  A 200 (-3.6A)
None
 1.25A 2zseA-4i3cA:
undetectable		 2zseA-4i3cA:
17.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		8 / 12 PHE A  17
PRO A  39
ASP A  81
ARG A  83
ARG A 112
VAL A 121
ARG A 132
TYR A 134
 BLR  A 200 (-3.6A)
None
None
None
BLR  A 200 (-3.6A)
BLR  A 200 (-4.7A)
BLR  A 200 (-3.5A)
None
 0.85A 3p6gA-4i3cA:
22.1		 3p6gA-4i3cA:
45.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		5 / 7 PHE A  17
ASP A  81
VAL A 121
ARG A 132
TYR A 134
 BLR  A 200 (-3.6A)
None
BLR  A 200 (-4.7A)
BLR  A 200 (-3.5A)
None
 0.89A 3p6hA-4i3cA:
22.0		 3p6hA-4i3cA:
45.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		4 / 6 GLU A  77
ILE A  55
THR A  65
TYR A 110
 BLR  A 200 (-4.0A)
BLR  A 200 (-3.6A)
BLR  A 200 ( 4.0A)
BLR  A 200 ( 4.0A)
 1.23A 4qwpA-4i3cA:
undetectable		 4qwpA-4i3cA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB302_1
(CHITOSANASE)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		4 / 5 GLU A  77
ILE A  55
THR A  65
TYR A 110
 BLR  A 200 (-4.0A)
BLR  A 200 (-3.6A)
BLR  A 200 ( 4.0A)
BLR  A 200 ( 4.0A)
 1.19A 4qwpB-4i3cA:
undetectable		 4qwpB-4i3cA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4i3c BILIRUBIN-INDUCIBLE
FLUORESCENT PROTEIN
UNAG
(Anguilla
japonica) 		5 / 12 PHE A  17
LEU A  21
LEU A  30
PRO A  39
LEU A  41
 BLR  A 200 (-3.6A)
BLR  A 200 (-3.7A)
BLR  A 200 (-3.6A)
None
BLR  A 200 (-4.1A)
 1.05A 5ljeA-4i3cA:
19.0		 5ljeA-4i3cA:
30.00