SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BLD'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 4m7e PROTEIN
BRASSINOSTEROID
INSENSITIVE 1
(Arabidopsis
thaliana) 		5 / 12 GLY A 604
ASP A 708
ILE A 706
GLY A 613
ILE A 600
 None
None
BLD  A 808 (-4.9A)
None
None
 0.97A 2hs1A-4m7eA:
undetectable		 2hs1A-4m7eA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 4m7e PROTEIN
BRASSINOSTEROID
INSENSITIVE 1
(Arabidopsis
thaliana) 		5 / 12 GLY A 604
ASP A 708
ILE A 706
GLY A 613
ILE A 600
 None
None
BLD  A 808 (-4.9A)
None
None
 0.93A 2rkgB-4m7eA:
undetectable		 2rkgB-4m7eA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1
(Arabidopsis
thaliana) 		5 / 11 GLY A 690
LEU A 668
ASN A 669
LEU A 716
LEU A 686
 BLD  A 804 ( 3.8A)
None
None
None
None
 1.33A 3ndvA-4j0mA:
undetectable
3ndvB-4j0mA:
undetectable		 3ndvA-4j0mA:
18.38
3ndvB-4j0mA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1
(Arabidopsis
thaliana) 		5 / 11 LEU A 686
GLY A 690
LEU A 668
ASN A 669
LEU A 716
 None
BLD  A 804 ( 3.8A)
None
None
None
 1.33A 3ndvA-4j0mA:
undetectable
3ndvB-4j0mA:
undetectable		 3ndvA-4j0mA:
18.38
3ndvB-4j0mA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1
(Arabidopsis
thaliana) 		5 / 11 GLY A 690
LEU A 668
ASN A 669
LEU A 716
LEU A 686
 BLD  A 804 ( 3.8A)
None
None
None
None
 1.31A 3ndvC-4j0mA:
undetectable
3ndvD-4j0mA:
undetectable		 3ndvC-4j0mA:
18.38
3ndvD-4j0mA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1
(Arabidopsis
thaliana) 		5 / 11 LEU A 686
GLY A 690
LEU A 668
ASN A 669
LEU A 716
 None
BLD  A 804 ( 3.8A)
None
None
None
 1.34A 3ndvC-4j0mA:
undetectable
3ndvD-4j0mA:
undetectable		 3ndvC-4j0mA:
18.38
3ndvD-4j0mA:
18.38