SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BII'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_B_STIB4_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
VAL A 484
GLY A 505
ASP A 564
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
BII  A1687 (-3.6A)
None
 0.86A 1opjB-2jkmA:
31.5		 1opjB-2jkmA:
41.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T46_A_STIA3_1
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		8 / 12 VAL A 436
ALA A 452
LYS A 454
GLU A 471
VAL A 484
GLY A 505
LEU A 553
ASP A 564
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
None
 0.73A 1t46A-2jkmA:
32.4		 1t46A-2jkmA:
33.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UWH_A_BAXA1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ALA A 452
GLU A 471
CYH A 502
LEU A 537
HIS A 544
GLY A 563
 BII  A1687 (-3.5A)
None
BII  A1687 (-4.1A)
None
None
BII  A1687 ( 3.9A)
 0.67A 1uwhA-2jkmA:
29.0		 1uwhA-2jkmA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		4 / 6 ILE A 428
VAL A 436
ILE A 483
ASP A 564
 BII  A1687 (-3.8A)
BII  A1687 ( 4.7A)
None
None
 0.67A 1uwhA-2jkmA:
29.0		 1uwhA-2jkmA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UWH_B_BAXB1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 ALA A 452
LYS A 454
GLU A 471
CYH A 502
LEU A 537
HIS A 544
GLY A 563
 BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
BII  A1687 (-4.1A)
None
None
BII  A1687 ( 3.9A)
 0.71A 1uwhB-2jkmA:
16.1		 1uwhB-2jkmA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		4 / 6 ILE A 428
VAL A 436
ILE A 483
ASP A 564
 BII  A1687 (-3.8A)
BII  A1687 ( 4.7A)
None
None
 0.67A 1uwhB-2jkmA:
16.1		 1uwhB-2jkmA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UWJ_A_BAXA1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
GLU A 471
CYH A 502
LEU A 537
HIS A 544
GLY A 563
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
BII  A1687 (-4.1A)
None
None
BII  A1687 ( 3.9A)
 0.74A 1uwjA-2jkmA:
28.1		 1uwjA-2jkmA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		4 / 7 ILE A 428
LYS A 454
ILE A 483
ASP A 564
 BII  A1687 (-3.8A)
BII  A1687 (-2.9A)
None
None
 0.75A 1uwjA-2jkmA:
28.1		 1uwjA-2jkmA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UWJ_B_BAXB1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		8 / 12 ILE A 428
VAL A 436
ALA A 452
GLU A 471
CYH A 502
LEU A 537
HIS A 544
GLY A 563
 BII  A1687 (-3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
BII  A1687 (-4.1A)
None
None
BII  A1687 ( 3.9A)
 0.86A 1uwjB-2jkmA:
10.6		 1uwjB-2jkmA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XBB_A_STIA1_1
(TYROSINE-PROTEIN
KINASE SYK)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 9 VAL A 436
ALA A 452
MET A 499
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.52A 1xbbA-2jkmA:
34.3		 1xbbA-2jkmA:
39.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_A_1N1A501_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 ALA A 452
GLU A 471
MET A 475
VAL A 484
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 (-3.5A)
None
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.65A 2gqgA-2jkmA:
33.0		 2gqgA-2jkmA:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_A_1N1A501_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 LYS A 454
GLU A 471
MET A 475
VAL A 484
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 (-2.9A)
None
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.64A 2gqgA-2jkmA:
33.0		 2gqgA-2jkmA:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_B_1N1B502_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		8 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
VAL A 484
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.64A 2gqgB-2jkmA:
32.5		 2gqgB-2jkmA:
40.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
ILE A 497
ASP A 564
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
None
 0.96A 2hyyD-2jkmA:
32.5		 2hyyD-2jkmA:
41.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
ILE A 497
GLY A 505
ASP A 564
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
BII  A1687 (-3.6A)
None
 0.75A 2oiqA-2jkmA:
32.2		 2oiqA-2jkmA:
39.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.62A 2oiqA-2jkmA:
32.2		 2oiqA-2jkmA:
39.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
VAL A 484
ILE A 497
ASP A 564
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
None
None
 0.87A 2pl0A-2jkmA:
30.6		 2pl0A-2jkmA:
38.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
VAL A 484
ILE A 497
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
None
BII  A1687 (-4.2A)
 0.91A 2pl0A-2jkmA:
30.6		 2pl0A-2jkmA:
38.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
LYS A 454
GLU A 471
MET A 475
VAL A 484
ILE A 497
ASP A 564
 BII  A1687 ( 4.7A)
BII  A1687 (-2.9A)
None
None
None
None
None
 0.93A 2pl0A-2jkmA:
30.6		 2pl0A-2jkmA:
38.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		8 / 12 ILE A 428
ALA A 452
LYS A 454
GLU A 471
MET A 475
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.75A 2y6oA-2jkmA:
34.6		 2y6oA-2jkmA:
41.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_A_B49A1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ILE A 428
VAL A 436
ALA A 452
GLY A 505
GLU A 506
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-3.6A)
BII  A1687 (-4.1A)
BII  A1687 (-4.2A)
 0.71A 2y7jA-2jkmA:
23.9		 2y7jA-2jkmA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_A_B49A1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ILE A 428
VAL A 436
ALA A 452
LEU A 501
GLY A 505
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.4A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.60A 2y7jA-2jkmA:
23.9		 2y7jA-2jkmA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_B_B49B1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 10 ILE A 428
VAL A 436
ALA A 452
LEU A 501
GLY A 505
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.4A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.69A 2y7jB-2jkmA:
24.4		 2y7jB-2jkmA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_C_B49C1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 10 ILE A 428
VAL A 436
ALA A 452
LEU A 501
GLY A 505
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.4A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.70A 2y7jC-2jkmA:
23.9		 2y7jC-2jkmA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_D_B49D1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 10 ILE A 428
VAL A 436
ALA A 452
LEU A 501
GLY A 505
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.4A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.69A 2y7jD-2jkmA:
24.2		 2y7jD-2jkmA:
22.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 8 ALA A 452
MET A 499
GLY A 505
LEU A 553
GLY A 563
 BII  A1687 (-3.5A)
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
BII  A1687 ( 3.9A)
 0.81A 2yfxA-2jkmA:
31.3		 2yfxA-2jkmA:
37.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 8 ALA A 452
MET A 499
LEU A 553
GLY A 563
ASP A 564
 BII  A1687 (-3.5A)
BII  A1687 (-4.1A)
BII  A1687 (-4.2A)
BII  A1687 ( 3.9A)
None
 0.98A 2yfxA-2jkmA:
31.3		 2yfxA-2jkmA:
37.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZVA_A_1N1A513_1
(TYROSINE-PROTEIN
KINASE LYN)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		8 / 12 ALA A 452
LYS A 454
GLU A 471
MET A 475
VAL A 484
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.64A 2zvaA-2jkmA:
32.6		 2zvaA-2jkmA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOX_A_EMHA901_1
(ALK TYROSINE KINASE
RECEPTOR)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 10 ALA A 452
LYS A 454
VAL A 484
LEU A 501
GLY A 505
LEU A 553
 BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
BII  A1687 (-4.4A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.68A 3aoxA-2jkmA:
31.1		 3aoxA-2jkmA:
35.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C7Q_A_XINA1172_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 GLY A 429
ALA A 452
LYS A 454
VAL A 484
CYH A 502
GLY A 505
LEU A 553
 BII  A1687 ( 3.8A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.55A 3c7qA-2jkmA:
24.1		 3c7qA-2jkmA:
34.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 10 VAL A 436
LYS A 454
VAL A 484
ILE A 497
ASP A 564
 BII  A1687 ( 4.7A)
BII  A1687 (-2.9A)
None
None
None
 0.97A 3cs9A-2jkmA:
32.5		 3cs9A-2jkmA:
40.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ALA A 452
MET A 475
GLY A 505
PHE A 542
HIS A 544
LEU A 553
 BII  A1687 (-3.5A)
None
BII  A1687 (-3.6A)
None
None
BII  A1687 (-4.2A)
 0.66A 3cs9A-2jkmA:
32.5		 3cs9A-2jkmA:
40.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ALA A 452
GLU A 471
MET A 475
PHE A 542
HIS A 544
ASP A 564
 BII  A1687 (-3.5A)
None
None
None
None
None
 1.00A 3cs9C-2jkmA:
31.9		 3cs9C-2jkmA:
40.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ALA A 452
GLU A 471
MET A 475
GLY A 505
PHE A 542
HIS A 544
 BII  A1687 (-3.5A)
None
None
BII  A1687 (-3.6A)
None
None
 0.67A 3cs9D-2jkmA:
32.0		 3cs9D-2jkmA:
40.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0E_A_B49A9000_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 11 VAL A 436
ALA A 452
VAL A 484
CYH A 502
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.51A 3g0eA-2jkmA:
29.8		 3g0eA-2jkmA:
31.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G5D_A_1N1A1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		8 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
VAL A 484
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.75A 3g5dA-2jkmA:
32.5		 3g5dA-2jkmA:
39.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G5D_B_1N1B1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		8 / 12 VAL A 436
ALA A 452
LYS A 454
GLU A 471
MET A 475
VAL A 484
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.82A 3g5dB-2jkmA:
32.8		 3g5dB-2jkmA:
39.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
VAL A 484
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
BII  A1687 (-4.2A)
 0.72A 3gvuA-2jkmA:
31.9		 3gvuA-2jkmA:
39.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K54_A_1N1A1_1
(TYROSINE-PROTEIN
KINASE BTK)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		8 / 12 ALA A 452
LYS A 454
GLU A 471
MET A 475
VAL A 484
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.64A 3k54A-2jkmA:
23.2		 3k54A-2jkmA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.77A 3k5vA-2jkmA:
31.6		 3k5vA-2jkmA:
41.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MIY_A_B49A1_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 11 ILE A 428
ALA A 452
LYS A 454
VAL A 484
GLY A 505
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.79A 3miyA-2jkmA:
33.1		 3miyA-2jkmA:
37.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		4 / 6 LYS A 454
VAL A 484
ILE A 497
ARG A 545
 BII  A1687 (-2.9A)
None
None
None
 0.94A 3mssA-2jkmA:
32.0		 3mssA-2jkmA:
41.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		4 / 7 LYS A 454
VAL A 484
ILE A 497
ARG A 545
 BII  A1687 (-2.9A)
None
None
None
 0.97A 3mssB-2jkmA:
32.0		 3mssB-2jkmA:
41.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		4 / 6 VAL A 436
LYS A 454
VAL A 484
ILE A 497
 BII  A1687 ( 4.7A)
BII  A1687 (-2.9A)
None
None
 0.85A 3mssD-2jkmA:
32.0		 3mssD-2jkmA:
41.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_A_STIA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 VAL A 436
ALA A 452
MET A 475
VAL A 484
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.51A 3oezA-2jkmA:
32.5		 3oezA-2jkmA:
39.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OG7_A_032A1_1
(AKAP9-BRAF FUSION
PROTEIN)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ILE A 428
VAL A 436
ALA A 452
LYS A 454
CYH A 502
GLY A 566
 BII  A1687 (-3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
BII  A1687 (-4.1A)
None
 0.82A 3og7A-2jkmA:
28.4		 3og7A-2jkmA:
29.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OG7_A_032A1_1
(AKAP9-BRAF FUSION
PROTEIN)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ILE A 428
VAL A 436
ALA A 452
LYS A 454
CYH A 502
PHE A 565
 BII  A1687 (-3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
BII  A1687 (-4.1A)
None
 1.07A 3og7A-2jkmA:
28.4		 3og7A-2jkmA:
29.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXZ_A_0LIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 ALA A 452
GLU A 471
MET A 475
VAL A 484
GLY A 505
HIS A 544
ASP A 564
 BII  A1687 (-3.5A)
None
None
None
BII  A1687 (-3.6A)
None
None
 0.94A 3oxzA-2jkmA:
32.4		 3oxzA-2jkmA:
41.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_A_1N1A1_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
MET A 475
VAL A 484
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.55A 3sxrA-2jkmA:
31.4		 3sxrA-2jkmA:
37.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SXR_B_1N1B2_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 VAL A 436
ALA A 452
MET A 475
VAL A 484
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.43A 3sxrB-2jkmA:
31.1		 3sxrB-2jkmA:
37.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UE4_B_DB8B601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
MET A 475
VAL A 484
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.57A 3ue4B-2jkmA:
33.6		 3ue4B-2jkmA:
42.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AG8_A_AXIA2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
LYS A 454
GLU A 471
VAL A 484
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.72A 4ag8A-2jkmA:
31.8		 4ag8A-2jkmA:
34.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AGD_A_B49A2000_1
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 11 ALA A 452
LYS A 454
VAL A 484
CYH A 502
GLY A 505
LEU A 553
 BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.64A 4agdA-2jkmA:
31.3		 4agdA-2jkmA:
31.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 ALA A 452
LYS A 454
GLU A 471
ILE A 497
HIS A 544
LEU A 553
ASP A 564
 BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
None
BII  A1687 (-4.2A)
None
 0.89A 4c8bA-2jkmA:
27.1		 4c8bA-2jkmA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 ALA A 452
LYS A 454
GLU A 471
ILE A 483
HIS A 544
LEU A 553
ASP A 564
 BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
None
BII  A1687 (-4.2A)
None
 0.92A 4c8bB-2jkmA:
27.2		 4c8bB-2jkmA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KS8_A_B49A701_1
(SERINE/THREONINE-PRO
TEIN KINASE PAK 6)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 10 ILE A 428
ALA A 452
VAL A 484
MET A 499
GLY A 505
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 (-3.5A)
None
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.42A 4ks8A-2jkmA:
24.2		 4ks8A-2jkmA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		4 / 7 VAL A 436
ALA A 452
MET A 499
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.1A)
BII  A1687 (-4.2A)
 0.76A 4l9iA-2jkmA:
7.6		 4l9iA-2jkmA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 8 VAL A 436
ALA A 452
LYS A 454
MET A 499
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
BII  A1687 (-4.1A)
BII  A1687 (-4.2A)
 0.88A 4l9iB-2jkmA:
20.6		 4l9iB-2jkmA:
19.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MKC_A_4MKA1503_1
(ALK TYROSINE KINASE
RECEPTOR)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 GLY A 431
VAL A 436
ALA A 452
LYS A 454
LEU A 501
GLY A 505
LEU A 553
 BII  A1687 ( 4.1A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
BII  A1687 (-4.4A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.51A 4mkcA-2jkmA:
32.5		 4mkcA-2jkmA:
36.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		4 / 6 VAL A 436
ALA A 452
LYS A 454
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
BII  A1687 (-4.2A)
 0.63A 4o0uA-2jkmA:
11.2		 4o0uA-2jkmA:
28.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_A_ADNA401_1
(CYCLIN-DEPENDENT
KINASE 9)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 8 ILE A 428
GLY A 431
VAL A 436
ALA A 452
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 ( 4.1A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.2A)
 0.30A 4ogrA-2jkmA:
23.7		 4ogrA-2jkmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_E_ADNE401_1
(CYCLIN-DEPENDENT
KINASE 9)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 7 ALA A 452
CYH A 502
ASN A 551
LEU A 553
ASP A 564
 BII  A1687 (-3.5A)
BII  A1687 (-4.1A)
None
BII  A1687 (-4.2A)
None
 1.05A 4ogrE-2jkmA:
22.8		 4ogrE-2jkmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_E_ADNE401_1
(CYCLIN-DEPENDENT
KINASE 9)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 7 GLY A 431
ALA A 452
ASN A 551
LEU A 553
ASP A 564
 BII  A1687 ( 4.1A)
BII  A1687 (-3.5A)
None
BII  A1687 (-4.2A)
None
 1.42A 4ogrE-2jkmA:
22.8		 4ogrE-2jkmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_I_ADNI401_1
(CYCLIN-DEPENDENT
KINASE 9)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 9 ILE A 428
GLY A 431
VAL A 436
ALA A 452
CYH A 502
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 ( 4.1A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.1A)
BII  A1687 (-4.2A)
 0.42A 4ogrI-2jkmA:
23.4		 4ogrI-2jkmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMZ_A_B49A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ILE A 428
GLY A 429
VAL A 436
ALA A 452
MET A 499
GLY A 505
 BII  A1687 (-3.8A)
BII  A1687 ( 3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
 0.77A 4qmzA-2jkmA:
26.1		 4qmzA-2jkmA:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMZ_A_B49A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ILE A 428
GLY A 429
VAL A 436
ALA A 452
MET A 499
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 ( 3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.1A)
BII  A1687 (-4.2A)
 0.59A 4qmzA-2jkmA:
26.1		 4qmzA-2jkmA:
29.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R7I_A_STIA1001_1
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		9 / 12 VAL A 436
ALA A 452
LYS A 454
GLU A 471
MET A 475
CYH A 502
LEU A 553
GLY A 563
ASP A 564
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
BII  A1687 (-4.1A)
BII  A1687 (-4.2A)
BII  A1687 ( 3.9A)
None
 0.88A 4r7iA-2jkmA:
31.0		 4r7iA-2jkmA:
31.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RZV_B_032B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 12 VAL A 436
ALA A 452
LYS A 454
CYH A 502
GLY A 566
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
BII  A1687 (-4.1A)
None
 0.67A 4rzvB-2jkmA:
26.8		 4rzvB-2jkmA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 12 ALA A 452
GLU A 471
MET A 475
HIS A 544
LEU A 553
 BII  A1687 (-3.5A)
None
None
None
BII  A1687 (-4.2A)
 0.67A 4tyjA-2jkmA:
32.8		 4tyjA-2jkmA:
37.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U0I_A_0LIA1001_2
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 ALA A 452
LYS A 454
CYH A 502
GLY A 505
HIS A 544
LEU A 553
ASP A 564
 BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
None
BII  A1687 (-4.2A)
None
 0.76A 4u0iA-2jkmA:
31.9		 4u0iA-2jkmA:
33.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 12 ALA A 452
GLU A 471
MET A 475
LEU A 537
HIS A 544
 BII  A1687 (-3.5A)
None
None
None
None
 0.82A 4v01B-2jkmA:
32.2		 4v01B-2jkmA:
37.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XEY_A_1N1A601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		8 / 12 VAL A 436
ALA A 452
LYS A 454
MET A 475
VAL A 484
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.72A 4xeyA-2jkmA:
33.2		 4xeyA-2jkmA:
33.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XEY_B_1N1B601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
LYS A 454
VAL A 484
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.66A 4xeyB-2jkmA:
32.5		 4xeyB-2jkmA:
33.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_B_1N1B600_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		8 / 12 ALA A 452
LYS A 454
GLU A 471
MET A 475
VAL A 484
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.67A 4xliB-2jkmA:
33.4		 4xliB-2jkmA:
40.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 VAL A 436
ALA A 452
LYS A 454
CYH A 502
GLY A 563
PHE A 565
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
BII  A1687 (-4.1A)
BII  A1687 ( 3.9A)
None
 0.87A 4xv2A-2jkmA:
28.0		 4xv2A-2jkmA:
28.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 12 ALA A 452
LYS A 454
CYH A 502
GLY A 563
PHE A 565
 BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
BII  A1687 (-4.1A)
BII  A1687 ( 3.9A)
None
 0.82A 4xv2B-2jkmA:
28.6		 4xv2B-2jkmA:
28.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZAU_A_YY3A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 8 GLY A 429
VAL A 436
ALA A 452
LEU A 501
GLY A 505
 BII  A1687 ( 3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.4A)
BII  A1687 (-3.6A)
 0.62A 4zauA-2jkmA:
32.9		 4zauA-2jkmA:
33.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_B_DB8B800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		4 / 10 ALA A 452
CYH A 502
GLY A 505
LEU A 553
 BII  A1687 (-3.5A)
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.27A 5ajqB-2jkmA:
23.4		 5ajqB-2jkmA:
28.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 12 VAL A 436
ALA A 452
LYS A 454
CYH A 502
GLY A 563
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
BII  A1687 (-4.1A)
BII  A1687 ( 3.9A)
 0.55A 5cswA-2jkmA:
28.1		 5cswA-2jkmA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 VAL A 436
ALA A 452
LYS A 454
CYH A 502
GLY A 563
PHE A 565
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
BII  A1687 (-4.1A)
BII  A1687 ( 3.9A)
None
 0.89A 5cswB-2jkmA:
28.0		 5cswB-2jkmA:
29.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_A_1N1A501_1
(PROTEIN-TYROSINE
KINASE 6)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 ARG A 426
VAL A 436
ALA A 452
LEU A 501
GLY A 505
LEU A 553
GLY A 563
 None
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.4A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
BII  A1687 ( 3.9A)
 0.79A 5h2uA-2jkmA:
29.6		 5h2uA-2jkmA:
35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_B_1N1B501_1
(PROTEIN-TYROSINE
KINASE 6)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
ILE A 497
LEU A 501
GLY A 505
LEU A 553
GLY A 563
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
BII  A1687 (-4.4A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
BII  A1687 ( 3.9A)
 0.78A 5h2uB-2jkmA:
29.8		 5h2uB-2jkmA:
35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_B_1N1B501_1
(PROTEIN-TYROSINE
KINASE 6)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 VAL A 436
ALA A 452
LYS A 454
ILE A 497
LEU A 501
GLY A 563
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
BII  A1687 (-4.4A)
BII  A1687 ( 3.9A)
 0.87A 5h2uB-2jkmA:
29.8		 5h2uB-2jkmA:
35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H2U_D_1N1D504_1
(PROTEIN-TYROSINE
KINASE 6)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
ILE A 497
LEU A 501
GLY A 505
LEU A 553
GLY A 563
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
BII  A1687 (-4.4A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
BII  A1687 ( 3.9A)
 0.77A 5h2uD-2jkmA:
29.7		 5h2uD-2jkmA:
35.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HI2_A_BAXA801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 ALA A 452
LYS A 454
GLU A 471
CYH A 502
LEU A 537
HIS A 544
GLY A 563
 BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
BII  A1687 (-4.1A)
None
None
BII  A1687 ( 3.9A)
 0.65A 5hi2A-2jkmA:
16.5		 5hi2A-2jkmA:
30.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 12 VAL A 436
ALA A 452
LYS A 454
ILE A 497
GLY A 563
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
BII  A1687 ( 3.9A)
 0.59A 5hieA-2jkmA:
27.3		 5hieA-2jkmA:
27.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 12 VAL A 436
ALA A 452
LYS A 454
ILE A 497
GLY A 563
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
BII  A1687 ( 3.9A)
 0.59A 5hieB-2jkmA:
27.1		 5hieB-2jkmA:
27.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 12 VAL A 436
ALA A 452
LYS A 454
ILE A 497
GLY A 563
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
BII  A1687 ( 3.9A)
 0.60A 5hieD-2jkmA:
26.8		 5hieD-2jkmA:
27.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9X_A_DB8A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ILE A 428
ALA A 452
GLU A 471
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 (-3.5A)
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.63A 5i9xA-2jkmA:
33.6		 5i9xA-2jkmA:
37.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 ILE A 428
ALA A 452
LYS A 454
GLU A 471
MET A 475
GLY A 505
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.63A 5i9yA-2jkmA:
33.6		 5i9yA-2jkmA:
37.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2I_A_LQQA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ILE A 428
GLY A 429
VAL A 436
ALA A 452
VAL A 484
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 ( 3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
BII  A1687 (-4.2A)
 0.73A 5l2iA-2jkmA:
10.3		 5l2iA-2jkmA:
26.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_1
(CYCLIN-DEPENDENT
KINASE 6)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ILE A 428
GLY A 429
VAL A 436
ALA A 452
VAL A 484
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 ( 3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
BII  A1687 (-4.2A)
 0.97A 5l2tA-2jkmA:
10.4		 5l2tA-2jkmA:
26.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 10 GLY A 429
VAL A 436
ALA A 452
MET A 499
LEU A 501
 BII  A1687 ( 3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.1A)
BII  A1687 (-4.4A)
 0.67A 5lw1E-2jkmA:
20.0		 5lw1E-2jkmA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_H_ADNH401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 9 GLY A 429
VAL A 436
ALA A 452
MET A 499
LEU A 501
 BII  A1687 ( 3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.1A)
BII  A1687 (-4.4A)
 0.59A 5lw1H-2jkmA:
20.2		 5lw1H-2jkmA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_1
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 ILE A 428
GLY A 429
VAL A 436
ALA A 452
LYS A 454
GLU A 471
GLY A 505
 BII  A1687 (-3.8A)
BII  A1687 ( 3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
BII  A1687 (-3.6A)
 0.79A 5mafA-2jkmA:
24.2		 5mafA-2jkmA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ALA A 452
MET A 475
VAL A 484
PHE A 542
HIS A 544
LEU A 553
 BII  A1687 (-3.5A)
None
None
None
None
BII  A1687 (-4.2A)
 0.65A 5mo4A-2jkmA:
27.2		 5mo4A-2jkmA:
27.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		4 / 8 GLU A 471
VAL A 436
GLY A 563
LEU A 553
 None
BII  A1687 ( 4.7A)
BII  A1687 ( 3.9A)
BII  A1687 (-4.2A)
 1.00A 5sxqA-2jkmA:
undetectable		 5sxqA-2jkmA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		4 / 8 GLU A 471
VAL A 436
GLY A 563
LEU A 553
 None
BII  A1687 ( 4.7A)
BII  A1687 ( 3.9A)
BII  A1687 (-4.2A)
 1.00A 5sxqB-2jkmA:
undetectable		 5sxqB-2jkmA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		4 / 8 GLU A 471
VAL A 436
GLY A 563
LEU A 553
 None
BII  A1687 ( 4.7A)
BII  A1687 ( 3.9A)
BII  A1687 (-4.2A)
 1.01A 5syjA-2jkmA:
undetectable		 5syjA-2jkmA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_1
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ALA A 452
GLU A 471
MET A 475
VAL A 484
GLY A 505
LEU A 553
 BII  A1687 (-3.5A)
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.78A 5te0A-2jkmA:
23.4		 5te0A-2jkmA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC3_A_DB8A601_1
(WEE1-LIKE PROTEIN
KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 ILE A 428
GLY A 429
ALA A 452
CYH A 502
GLY A 505
ASP A 564
 BII  A1687 (-3.8A)
BII  A1687 ( 3.8A)
BII  A1687 (-3.5A)
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
None
 0.79A 5vc3A-2jkmA:
23.2		 5vc3A-2jkmA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W5V_A_ANWA701_0
(SERINE/THREONINE-PRO
TEIN KINASE TBK1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		5 / 9 ALA A 452
VAL A 484
MET A 499
CYH A 502
GLY A 505
 BII  A1687 (-3.5A)
None
BII  A1687 (-4.1A)
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
 0.49A 5w5vA-2jkmA:
11.9		 5w5vA-2jkmA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7Z_A_IREA401_0
(CYCLIN-G-ASSOCIATED
KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 VAL A 436
ALA A 452
LEU A 501
CYH A 502
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.4A)
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.41A 5y7zA-2jkmA:
22.8		 5y7zA-2jkmA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7Z_A_IREA401_0
(CYCLIN-G-ASSOCIATED
KINASE)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		6 / 12 VAL A 436
ALA A 452
LEU A 501
CYH A 502
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-4.4A)
BII  A1687 (-4.1A)
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.41A 5y7zA-2jkmA:
22.8		 5y7zA-2jkmA:
26.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FNM_A_1N1A1001_1
(-)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		9 / 12 ILE A 428
VAL A 436
ALA A 452
LYS A 454
GLU A 471
MET A 475
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 (-3.8A)
BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
BII  A1687 (-2.9A)
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 1.07A 6fnmA-2jkmA:
34.9		 6fnmA-2jkmA:
41.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
VAL A 484
ILE A 497
ASP A 564
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
None
None
 0.94A 6hd4B-2jkmA:
31.4		 6hd4B-2jkmA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
VAL A 484
ILE A 497
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
None
BII  A1687 (-4.2A)
 0.82A 6hd4B-2jkmA:
31.4		 6hd4B-2jkmA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
VAL A 484
ILE A 497
ASP A 564
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
None
None
 0.87A 6hd6A-2jkmA:
31.6		 6hd6A-2jkmA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
ALA A 452
GLU A 471
MET A 475
VAL A 484
ILE A 497
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
None
BII  A1687 (-4.2A)
 0.77A 6hd6A-2jkmA:
31.6		 6hd6A-2jkmA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 2jkm FOCAL ADHESION
KINASE 1
(Gallus
gallus) 		7 / 12 VAL A 436
LYS A 454
GLU A 471
MET A 475
VAL A 484
ILE A 497
ASP A 564
 BII  A1687 ( 4.7A)
BII  A1687 (-2.9A)
None
None
None
None
None
 0.98A 6hd6A-2jkmA:
31.6		 6hd6A-2jkmA:
11.87