SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BI9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T46_A_STIA3_1 (HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	ALA A 192 LYS A 194 GLU A 236 LEU A 240 VAL A 249 GLY A 273 LEU A 319 ASP A 330	BI9 A 501 (-3.3A) NH4 A 506 ( 4.4A) NH4 A 506 (-3.0A) None None BI9 A 501 (-3.3A) BI9 A 501 (-4.7A) None	1.01A	1t46A-6bqlA: 21.8	1t46A-6bqlA: 11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T46_A_STIA3_1 (HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	VAL A 179 ALA A 192 LYS A 194 GLU A 236 VAL A 249 GLY A 273 LEU A 319 ASP A 330	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) NH4 A 506 ( 4.4A) NH4 A 506 (-3.0A) None BI9 A 501 (-3.3A) BI9 A 501 (-4.7A) None	1.07A	1t46A-6bqlA: 21.8	1t46A-6bqlA: 11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XBB_A_STIA1_1 (TYROSINE-PROTEIN KINASE SYK)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 9	VAL A 179 ALA A 192 GLY A 273 PRO A 274 LEU A 319	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) BI9 A 501 (-3.3A) None BI9 A 501 (-4.7A)	0.36A	1xbbA-6bqlA: 25.7	1xbbA-6bqlA: 14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	ILE A 171 VAL A 179 LYS A 194 VAL A 249 PHE A 267 VAL A 270 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 ( 4.8A) NH4 A 506 ( 4.4A) None BI9 A 501 ( 4.2A) BI9 A 501 (-4.0A) BI9 A 501 (-4.7A)	0.87A	2eufB-6bqlA: 27.1	2eufB-6bqlA: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	VAL A 179 LYS A 194 VAL A 249 PHE A 267 VAL A 270 ASN A 317 LEU A 319 ALA A 329	BI9 A 501 ( 4.8A) NH4 A 506 ( 4.4A) None BI9 A 501 ( 4.2A) BI9 A 501 (-4.0A) BI9 A 501 (-4.5A) BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A)	0.93A	2eufB-6bqlA: 27.1	2eufB-6bqlA: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 249 PHE A 267 VAL A 270 ASN A 317 LEU A 319 ALA A 329 ASP A 330	None BI9 A 501 ( 4.2A) BI9 A 501 (-4.0A) BI9 A 501 (-4.5A) BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A) None	0.84A	2eufB-6bqlA: 27.1	2eufB-6bqlA: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_A_B49A1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	ILE A 171 VAL A 179 ALA A 192 PHE A 267 LEU A 269 GLY A 273 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) BI9 A 501 ( 4.2A) BI9 A 501 (-4.4A) BI9 A 501 (-3.3A) BI9 A 501 (-4.7A)	0.43A	2y7jA-6bqlA: 31.7	2y7jA-6bqlA: 12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_B_B49B1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 10	ILE A 171 VAL A 179 ALA A 192 PHE A 267 LEU A 269 GLY A 273 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) BI9 A 501 ( 4.2A) BI9 A 501 (-4.4A) BI9 A 501 (-3.3A) BI9 A 501 (-4.7A)	0.39A	2y7jB-6bqlA: 31.7	2y7jB-6bqlA: 12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_C_B49C1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 10	ILE A 171 VAL A 179 ALA A 192 PHE A 267 LEU A 269 GLY A 273 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) BI9 A 501 ( 4.2A) BI9 A 501 (-4.4A) BI9 A 501 (-3.3A) BI9 A 501 (-4.7A)	0.41A	2y7jC-6bqlA: 31.7	2y7jC-6bqlA: 12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_D_B49D1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 10	ILE A 171 VAL A 179 ALA A 192 PHE A 267 LEU A 269 GLY A 273 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) BI9 A 501 ( 4.2A) BI9 A 501 (-4.4A) BI9 A 501 (-3.3A) BI9 A 501 (-4.7A)	0.41A	2y7jD-6bqlA: 31.6	2y7jD-6bqlA: 12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOX_A_EMHA901_1 (ALK TYROSINE KINASE RECEPTOR)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 10	ALA A 192 LYS A 194 VAL A 249 LEU A 269 GLY A 273 LEU A 319	BI9 A 501 (-3.3A) NH4 A 506 ( 4.4A) None BI9 A 501 (-4.4A) BI9 A 501 (-3.3A) BI9 A 501 (-4.7A)	0.48A	3aoxA-6bqlA: 22.3	3aoxA-6bqlA: 13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BBT_B_FMMB91_1 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	VAL A 179 ALA A 192 LEU A 251 LEU A 269 GLY A 273 LEU A 319	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) None BI9 A 501 (-4.4A) BI9 A 501 (-3.3A) BI9 A 501 (-4.7A)	0.55A	3bbtB-6bqlA: 20.9	3bbtB-6bqlA: 12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GCS_A_BAXA401_2 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	4 / 6	VAL A 248 LEU A 269 ILE A 308 ILE A 328	None BI9 A 501 (-4.4A) None None	0.82A	3gcsA-6bqlA: 21.2	3gcsA-6bqlA: 12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GVU_A_STIA1001_1 (TYROSINE-PROTEIN KINASE ABL2)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 ILE A 239 VAL A 249 LEU A 319 ALA A 329 ASP A 330	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) None None BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A) None	0.96A	3gvuA-6bqlA: 22.1	3gvuA-6bqlA: 15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IK3_A_0LIA1_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	ALA A 192 VAL A 249 HIS A 310 LEU A 319 ALA A 329 ASP A 330	BI9 A 501 (-3.3A) None None BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A) None	0.86A	3ik3A-6bqlA: 21.8	3ik3A-6bqlA: 16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IK3_B_0LIB2_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	ALA A 192 VAL A 249 HIS A 310 LEU A 319 ALA A 329	BI9 A 501 (-3.3A) None None BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A)	0.53A	3ik3B-6bqlA: 21.6	3ik3B-6bqlA: 16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MIY_A_B49A1_1 (TYROSINE-PROTEIN KINASE ITK/TSK)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 11	ILE A 171 ALA A 192 LYS A 194 VAL A 249 PHE A 267 GLY A 273 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 (-3.3A) NH4 A 506 ( 4.4A) None BI9 A 501 ( 4.2A) BI9 A 501 (-3.3A) BI9 A 501 (-4.7A)	0.59A	3miyA-6bqlA: 23.0	3miyA-6bqlA: 14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MIY_B_B49B2_1 (TYROSINE-PROTEIN KINASE ITK/TSK)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 9	ILE A 171 ALA A 192 LYS A 194 PHE A 267 GLY A 273 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 (-3.3A) NH4 A 506 ( 4.4A) BI9 A 501 ( 4.2A) BI9 A 501 (-3.3A) BI9 A 501 (-4.7A)	0.58A	3miyB-6bqlA: 23.1	3miyB-6bqlA: 14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXZ_A_0LIA1_1 (TYROSINE-PROTEIN KINASE ABL1)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	ALA A 192 VAL A 249 GLY A 273 HIS A 310 ALA A 329 ASP A 330	BI9 A 501 (-3.3A) None BI9 A 501 (-3.3A) None NH4 A 506 ( 3.7A) None	0.88A	3oxzA-6bqlA: 21.7	3oxzA-6bqlA: 16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PYY_B_STIB4_1 (V-ABL ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1 ISOFORM B VARIANT)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	VAL A 179 ALA A 192 VAL A 249 LEU A 319 ALA A 329 ASP A 330	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) None BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A) None	0.63A	3pyyB-6bqlA: 21.7	3pyyB-6bqlA: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RGF_A_BAXA465_1 (CYCLIN-DEPENDENT KINASE 8)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 LEU A 240 PHE A 267 LEU A 303 HIS A 310 ALA A 329	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) None BI9 A 501 ( 4.2A) None None NH4 A 506 ( 3.7A)	0.84A	3rgfA-6bqlA: 5.7	3rgfA-6bqlA: 10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TI1_A_B49A299_1 (CYCLIN-DEPENDENT KINASE 2)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 9	ILE A 171 ALA A 192 VAL A 249 PHE A 267 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 (-3.3A) None BI9 A 501 ( 4.2A) BI9 A 501 (-4.7A)	0.69A	3ti1A-6bqlA: 22.4	3ti1A-6bqlA: 12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WZE_A_BAXA1201_2 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 8	VAL A 248 VAL A 249 LEU A 319 ILE A 328 ASP A 330	None None BI9 A 501 (-4.7A) None None	0.61A	3wzeA-6bqlA: 22.1	3wzeA-6bqlA: 13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ANQ_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 9	VAL A 179 ALA A 192 GLY A 273 LEU A 319 ALA A 329 ASP A 330	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) BI9 A 501 (-3.3A) BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A) None	0.70A	4anqA-6bqlA: 22.8	4anqA-6bqlA: 12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ANS_A_VGHA9000_1 (ALK TYROSINE KINASE RECEPTOR)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 9	VAL A 179 ALA A 192 GLY A 273 LEU A 319 ALA A 329 ASP A 330	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) BI9 A 501 (-3.3A) BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A) None	0.68A	4ansA-6bqlA: 22.7	4ansA-6bqlA: 12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BKJ_B_STIB1000_1 (EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	VAL A 179 ALA A 192 MET A 265 LEU A 319 ALA A 329 ASP A 330	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) None BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A) None	0.88A	4bkjB-6bqlA: 21.4	4bkjB-6bqlA: 14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C8B_A_0LIA1000_1 (RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	ALA A 192 LYS A 194 LEU A 240 HIS A 310 LEU A 319 ALA A 329 ASP A 330	BI9 A 501 (-3.3A) NH4 A 506 ( 4.4A) None None BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A) None	0.85A	4c8bA-6bqlA: 22.9	4c8bA-6bqlA: 14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C8B_B_0LIB1000_1 (RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	ALA A 192 LYS A 194 LEU A 240 HIS A 310 LEU A 319 ALA A 329 ASP A 330	BI9 A 501 (-3.3A) NH4 A 506 ( 4.4A) None None BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A) None	0.89A	4c8bB-6bqlA: 22.7	4c8bB-6bqlA: 14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KS8_A_B49A701_1 (SERINE/THREONINE-PRO TEIN KINASE PAK 6)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 10	ILE A 171 ALA A 192 VAL A 249 GLY A 273 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 (-3.3A) None BI9 A 501 (-3.3A) BI9 A 501 (-4.7A)	0.42A	4ks8A-6bqlA: 29.7	4ks8A-6bqlA: 15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MXY_B_DB8B601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 GLU A 236 VAL A 249 GLY A 273 LEU A 319 ALA A 329	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) NH4 A 506 (-3.0A) None BI9 A 501 (-3.3A) BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A)	0.64A	4mxyB-6bqlA: 24.5	4mxyB-6bqlA: 15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MXZ_B_DB8B601_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 GLU A 236 VAL A 249 GLY A 273 LEU A 319 ALA A 329	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) NH4 A 506 (-3.0A) None BI9 A 501 (-3.3A) BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A)	0.64A	4mxzB-6bqlA: 24.5	4mxzB-6bqlA: 15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OR0_A_NPSA602_1 (SERUM ALBUMIN)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 9	PHE A 267 ALA A 192 ALA A 182 LEU A 162 VAL A 252	BI9 A 501 ( 4.2A) BI9 A 501 (-3.3A) None None None	1.31A	4or0A-6bqlA: 2.5	4or0A-6bqlA: 9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RZ7_A_1E8A901_1 (CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 10	ILE A 171 ALA A 192 LYS A 194 LEU A 269 VAL A 270 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 (-3.3A) NH4 A 506 ( 4.4A) BI9 A 501 (-4.4A) BI9 A 501 (-4.0A) BI9 A 501 (-4.7A)	0.65A	4rz7A-6bqlA: 11.8	4rz7A-6bqlA: 6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U0I_A_0LIA1001_2 (MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT,MAST/STEM CELL GROWTH FACTOR RECEPTOR KIT)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	ALA A 192 LYS A 194 LEU A 240 GLY A 273 HIS A 310 LEU A 319 ASP A 330	BI9 A 501 (-3.3A) NH4 A 506 ( 4.4A) None BI9 A 501 (-3.3A) None BI9 A 501 (-4.7A) None	0.99A	4u0iA-6bqlA: 21.6	4u0iA-6bqlA: 11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UXQ_A_0LIA1752_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	ALA A 192 LEU A 303 HIS A 310 LEU A 319 ALA A 329	BI9 A 501 (-3.3A) None None BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A)	0.39A	4uxqA-6bqlA: 22.0	4uxqA-6bqlA: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XEY_B_1N1B601_1 (TYROSINE-PROTEIN KINASE ABL1)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 LYS A 194 VAL A 249 GLY A 273 LEU A 319 ALA A 329	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) NH4 A 506 ( 4.4A) None BI9 A 501 (-3.3A) BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A)	0.66A	4xeyB-6bqlA: 23.8	4xeyB-6bqlA: 13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I9Y_A_1N1A1001_1 (EPHRIN TYPE-A RECEPTOR 2)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	ILE A 171 ALA A 192 LYS A 194 GLU A 236 GLY A 273 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 (-3.3A) NH4 A 506 ( 4.4A) NH4 A 506 (-3.0A) BI9 A 501 (-3.3A) BI9 A 501 (-4.7A)	0.62A	5i9yA-6bqlA: 23.1	5i9yA-6bqlA: 13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IZJ_G_AZ1G2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 47P-AZ1-DAR-DAR)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 7	GLY A 172 GLY A 174 SER A 175 VAL A 179 LYS A 194 LEU A 196	BI9 A 501 (-3.6A) None ACT A 504 (-3.3A) BI9 A 501 ( 4.8A) NH4 A 506 ( 4.4A) None	0.60A	5izjA-6bqlA: 29.2	5izjA-6bqlA: 13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J5X_B_AZ1B2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 47P-AZ1-DAL-DAR-DAR- DAR-DAR)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 7	GLY A 172 GLY A 174 SER A 175 VAL A 179 LYS A 194	BI9 A 501 (-3.6A) None ACT A 504 (-3.3A) BI9 A 501 ( 4.8A) NH4 A 506 ( 4.4A)	0.46A	5j5xA-6bqlA: 29.4	5j5xA-6bqlA: 13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	GLY A 172 VAL A 179 ALA A 192 VAL A 249 PHE A 267 LEU A 319 ALA A 329	BI9 A 501 (-3.6A) BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) None BI9 A 501 ( 4.2A) BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A)	0.84A	5l2iA-6bqlA: 8.0	5l2iA-6bqlA: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2T_A_6ZZA900_1 (CYCLIN-DEPENDENT KINASE 6)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	VAL A 179 ALA A 192 VAL A 249 PHE A 267 LEU A 319 ALA A 329	BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) None BI9 A 501 ( 4.2A) BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A)	0.90A	5l2tA-6bqlA: 8.0	5l2tA-6bqlA: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MO4_A_NILA601_2 (TYROSINE-PROTEIN KINASE ABL1)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	ALA A 192 VAL A 249 HIS A 310 LEU A 319 ALA A 329	BI9 A 501 (-3.3A) None None BI9 A 501 (-4.7A) NH4 A 506 ( 3.7A)	0.48A	5mo4A-6bqlA: 18.8	5mo4A-6bqlA: 10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VC3_A_DB8A601_1 (WEE1-LIKE PROTEIN KINASE)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	ILE A 171 GLY A 172 ALA A 192 GLU A 236 GLY A 273 ASP A 330	BI9 A 501 (-4.0A) BI9 A 501 (-3.6A) BI9 A 501 (-3.3A) NH4 A 506 (-3.0A) BI9 A 501 (-3.3A) None	0.88A	5vc3A-6bqlA: 26.5	5vc3A-6bqlA: 16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XV7_A_EMHA705_1 (SERINE-ARGININE (SR) PROTEIN KINASE 1)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	GLY A 172 VAL A 179 ALA A 192 PHE A 267 ALA A 329	BI9 A 501 (-3.6A) BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) BI9 A 501 ( 4.2A) NH4 A 506 ( 3.7A)	0.31A	5xv7A-6bqlA: 25.5	5xv7A-6bqlA: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FNM_A_1N1A1001_1 (-)	6bql	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	ILE A 171 VAL A 179 ALA A 192 LYS A 194 GLU A 236 GLY A 273 LEU A 319	BI9 A 501 (-4.0A) BI9 A 501 ( 4.8A) BI9 A 501 (-3.3A) NH4 A 506 ( 4.4A) NH4 A 506 (-3.0A) BI9 A 501 (-3.3A) BI9 A 501 (-4.7A)	0.66A	6fnmA-6bqlA: 23.9	6fnmA-6bqlA: 13.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1T46_A_STIA3_1","HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",8,"ALA A 192;LYS A 194;GLU A 236;LEU A 240;VAL A 249;GLY A 273;LEU A 319;ASP A 330","BI9 A 501 (-3.3A);NH4 A 506 ( 4.4A);NH4 A 506 (-3.0A);None;None;BI9 A 501 (-3.3A);BI9 A 501 (-4.7A);None","1.01A","1t46A-6bqlA:21.8",null],["1T46_A_STIA3_1","HOMO SAPIENS V-KIT HARDY-ZUCKERMAN 4 FELINE SARCOMA VIRAL ONCOGENE HOMOLOG","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",8,"VAL A 179;ALA A 192;LYS A 194;GLU A 236;VAL A 249;GLY A 273;LEU A 319;ASP A 330","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);NH4 A 506 ( 4.4A);NH4 A 506 (-3.0A);None;BI9 A 501 (-3.3A);BI9 A 501 (-4.7A);None","1.07A","1t46A-6bqlA:21.8","1t46A-6bqlA:11.76"],["1XBB_A_STIA1_1","TYROSINE-PROTEIN KINASE SYK","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"VAL A 179;ALA A 192;GLY A 273;PRO A 274;LEU A 319","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);BI9 A 501 (-3.3A);None;BI9 A 501 (-4.7A)","0.36A","1xbbA-6bqlA:25.7","1t46A-6bqlA:11.76"],["2EUF_B_LQQB401_1","CELL DIVISION PROTEIN KINASE 6","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;VAL A 179;LYS A 194;VAL A 249;PHE A 267;VAL A 270;LEU A 319","BI9 A 501 (-4.0A);BI9 A 501 ( 4.8A);NH4 A 506 ( 4.4A);None;BI9 A 501 ( 4.2A);BI9 A 501 (-4.0A);BI9 A 501 (-4.7A)","0.87A","2eufB-6bqlA:27.1","1xbbA-6bqlA:14.69"],["2EUF_B_LQQB401_1","CELL DIVISION PROTEIN KINASE 6","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",8,"VAL A 179;LYS A 194;VAL A 249;PHE A 267;VAL A 270;ASN A 317;LEU A 319;ALA A 329","BI9 A 501 ( 4.8A);NH4 A 506 ( 4.4A);None;BI9 A 501 ( 4.2A);BI9 A 501 (-4.0A);BI9 A 501 (-4.5A);BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A)","0.93A","2eufB-6bqlA:27.1","2eufB-6bqlA:13.64"],["2EUF_B_LQQB401_1","CELL DIVISION PROTEIN KINASE 6","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 249;PHE A 267;VAL A 270;ASN A 317;LEU A 319;ALA A 329;ASP A 330","None;BI9 A 501 ( 4.2A);BI9 A 501 (-4.0A);BI9 A 501 (-4.5A);BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A);None","0.84A","2eufB-6bqlA:27.1","2eufB-6bqlA:13.64"],["2Y7J_A_B49A1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;VAL A 179;ALA A 192;PHE A 267;LEU A 269;GLY A 273;LEU A 319","BI9 A 501 (-4.0A);BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);BI9 A 501 ( 4.2A);BI9 A 501 (-4.4A);BI9 A 501 (-3.3A);BI9 A 501 (-4.7A)","0.43A","2y7jA-6bqlA:31.7","2eufB-6bqlA:13.64"],["2Y7J_B_B49B1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;VAL A 179;ALA A 192;PHE A 267;LEU A 269;GLY A 273;LEU A 319","BI9 A 501 (-4.0A);BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);BI9 A 501 ( 4.2A);BI9 A 501 (-4.4A);BI9 A 501 (-3.3A);BI9 A 501 (-4.7A)","0.39A","2y7jB-6bqlA:31.7","2y7jA-6bqlA:12.00"],["2Y7J_C_B49C1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;VAL A 179;ALA A 192;PHE A 267;LEU A 269;GLY A 273;LEU A 319","BI9 A 501 (-4.0A);BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);BI9 A 501 ( 4.2A);BI9 A 501 (-4.4A);BI9 A 501 (-3.3A);BI9 A 501 (-4.7A)","0.41A","2y7jC-6bqlA:31.7","2y7jB-6bqlA:12.00"],["2Y7J_D_B49D1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;VAL A 179;ALA A 192;PHE A 267;LEU A 269;GLY A 273;LEU A 319","BI9 A 501 (-4.0A);BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);BI9 A 501 ( 4.2A);BI9 A 501 (-4.4A);BI9 A 501 (-3.3A);BI9 A 501 (-4.7A)","0.41A","2y7jD-6bqlA:31.6","2y7jC-6bqlA:12.00"],["3AOX_A_EMHA901_1","ALK TYROSINE KINASE RECEPTOR","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ALA A 192;LYS A 194;VAL A 249;LEU A 269;GLY A 273;LEU A 319","BI9 A 501 (-3.3A);NH4 A 506 ( 4.4A);None;BI9 A 501 (-4.4A);BI9 A 501 (-3.3A);BI9 A 501 (-4.7A)","0.48A","3aoxA-6bqlA:22.3","2y7jD-6bqlA:12.00"],["3BBT_B_FMMB91_1","RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"VAL A 179;ALA A 192;LEU A 251;LEU A 269;GLY A 273;LEU A 319","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);None;BI9 A 501 (-4.4A);BI9 A 501 (-3.3A);BI9 A 501 (-4.7A)","0.55A","3bbtB-6bqlA:20.9","3aoxA-6bqlA:13.41"],["3GCS_A_BAXA401_2","MITOGEN-ACTIVATED PROTEIN KINASE 14","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",4,"VAL A 248;LEU A 269;ILE A 308;ILE A 328","None;BI9 A 501 (-4.4A);None;None","0.82A","3gcsA-6bqlA:21.2","3bbtB-6bqlA:12.20"],["3GVU_A_STIA1001_1","TYROSINE-PROTEIN KINASE ABL2","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;ILE A 239;VAL A 249;LEU A 319;ALA A 329;ASP A 330","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);None;None;BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A);None","0.96A","3gvuA-6bqlA:22.1","3gcsA-6bqlA:12.85"],["3IK3_A_0LIA1_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ALA A 192;VAL A 249;HIS A 310;LEU A 319;ALA A 329;ASP A 330","BI9 A 501 (-3.3A);None;None;BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A);None","0.86A","3ik3A-6bqlA:21.8","3gvuA-6bqlA:15.94"],["3IK3_B_0LIB2_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ALA A 192;VAL A 249;HIS A 310;LEU A 319;ALA A 329","BI9 A 501 (-3.3A);None;None;BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A)","0.53A","3ik3B-6bqlA:21.6","3ik3A-6bqlA:16.29"],["3MIY_A_B49A1_1","TYROSINE-PROTEIN KINASE ITK\/TSK","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;ALA A 192;LYS A 194;VAL A 249;PHE A 267;GLY A 273;LEU A 319","BI9 A 501 (-4.0A);BI9 A 501 (-3.3A);NH4 A 506 ( 4.4A);None;BI9 A 501 ( 4.2A);BI9 A 501 (-3.3A);BI9 A 501 (-4.7A)","0.59A","3miyA-6bqlA:23.0","3ik3B-6bqlA:16.29"],["3MIY_B_B49B2_1","TYROSINE-PROTEIN KINASE ITK\/TSK","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ILE A 171;ALA A 192;LYS A 194;PHE A 267;GLY A 273;LEU A 319","BI9 A 501 (-4.0A);BI9 A 501 (-3.3A);NH4 A 506 ( 4.4A);BI9 A 501 ( 4.2A);BI9 A 501 (-3.3A);BI9 A 501 (-4.7A)","0.58A","3miyB-6bqlA:23.1","3miyA-6bqlA:14.94"],["3OXZ_A_0LIA1_1","TYROSINE-PROTEIN KINASE ABL1","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ALA A 192;VAL A 249;GLY A 273;HIS A 310;ALA A 329;ASP A 330","BI9 A 501 (-3.3A);None;BI9 A 501 (-3.3A);None;NH4 A 506 ( 3.7A);None","0.88A","3oxzA-6bqlA:21.7","3miyB-6bqlA:14.94"],["3PYY_B_STIB4_1","V-ABL ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1 ISOFORM B VARIANT","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"VAL A 179;ALA A 192;VAL A 249;LEU A 319;ALA A 329;ASP A 330","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);None;BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A);None","0.63A","3pyyB-6bqlA:21.7","3oxzA-6bqlA:16.29"],["3RGF_A_BAXA465_1","CYCLIN-DEPENDENT KINASE 8","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;LEU A 240;PHE A 267;LEU A 303;HIS A 310;ALA A 329","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);None;BI9 A 501 ( 4.2A);None;None;NH4 A 506 ( 3.7A)","0.84A","3rgfA-6bqlA:5.7","3pyyB-6bqlA:15.47"],["3TI1_A_B49A299_1","CYCLIN-DEPENDENT KINASE 2","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ILE A 171;ALA A 192;VAL A 249;PHE A 267;LEU A 319","BI9 A 501 (-4.0A);BI9 A 501 (-3.3A);None;BI9 A 501 ( 4.2A);BI9 A 501 (-4.7A)","0.69A","3ti1A-6bqlA:22.4","3rgfA-6bqlA:10.37"],["3WZE_A_BAXA1201_2","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"VAL A 248;VAL A 249;LEU A 319;ILE A 328;ASP A 330","None;None;BI9 A 501 (-4.7A);None;None","0.61A","3wzeA-6bqlA:22.1","3ti1A-6bqlA:12.96"],["4ANQ_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"VAL A 179;ALA A 192;GLY A 273;LEU A 319;ALA A 329;ASP A 330","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);BI9 A 501 (-3.3A);BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A);None","0.70A","4anqA-6bqlA:22.8","3wzeA-6bqlA:13.11"],["4ANS_A_VGHA9000_1","ALK TYROSINE KINASE RECEPTOR","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"VAL A 179;ALA A 192;GLY A 273;LEU A 319;ALA A 329;ASP A 330","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);BI9 A 501 (-3.3A);BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A);None","0.68A","4ansA-6bqlA:22.7","4anqA-6bqlA:12.61"],["4BKJ_B_STIB1000_1","EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"VAL A 179;ALA A 192;MET A 265;LEU A 319;ALA A 329;ASP A 330","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);None;BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A);None","0.88A","4bkjB-6bqlA:21.4","4ansA-6bqlA:12.61"],["4C8B_A_0LIA1000_1","RECEPTOR-INTERACTING SERINE\/THREONINE-PROTEIN KINASE 2","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ALA A 192;LYS A 194;LEU A 240;HIS A 310;LEU A 319;ALA A 329;ASP A 330","BI9 A 501 (-3.3A);NH4 A 506 ( 4.4A);None;None;BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A);None","0.85A","4c8bA-6bqlA:22.9","4bkjB-6bqlA:14.15"],["4C8B_B_0LIB1000_1","RECEPTOR-INTERACTING SERINE\/THREONINE-PROTEIN KINASE 2","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ALA A 192;LYS A 194;LEU A 240;HIS A 310;LEU A 319;ALA A 329;ASP A 330","BI9 A 501 (-3.3A);NH4 A 506 ( 4.4A);None;None;BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A);None","0.89A","4c8bB-6bqlA:22.7","4c8bA-6bqlA:14.05"],["4KS8_A_B49A701_1","SERINE\/THREONINE-PROTEIN KINASE PAK 6","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ILE A 171;ALA A 192;VAL A 249;GLY A 273;LEU A 319","BI9 A 501 (-4.0A);BI9 A 501 (-3.3A);None;BI9 A 501 (-3.3A);BI9 A 501 (-4.7A)","0.42A","4ks8A-6bqlA:29.7","4c8bB-6bqlA:14.05"],["4MXY_B_DB8B601_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;GLU A 236;VAL A 249;GLY A 273;LEU A 319;ALA A 329","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);NH4 A 506 (-3.0A);None;BI9 A 501 (-3.3A);BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A)","0.64A","4mxyB-6bqlA:24.5","4ks8A-6bqlA:15.91"],["4MXZ_B_DB8B601_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;GLU A 236;VAL A 249;GLY A 273;LEU A 319;ALA A 329","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);NH4 A 506 (-3.0A);None;BI9 A 501 (-3.3A);BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A)","0.64A","4mxzB-6bqlA:24.5","4mxyB-6bqlA:15.38"],["4OR0_A_NPSA602_1","SERUM ALBUMIN","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"PHE A 267;ALA A 192;ALA A 182;LEU A 162;VAL A 252","BI9 A 501 ( 4.2A);BI9 A 501 (-3.3A);None;None;None","1.31A","4or0A-6bqlA:2.5","4mxzB-6bqlA:15.38"],["4RZ7_A_1E8A901_1","CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ILE A 171;ALA A 192;LYS A 194;LEU A 269;VAL A 270;LEU A 319","BI9 A 501 (-4.0A);BI9 A 501 (-3.3A);NH4 A 506 ( 4.4A);BI9 A 501 (-4.4A);BI9 A 501 (-4.0A);BI9 A 501 (-4.7A)","0.65A","4rz7A-6bqlA:11.8","4or0A-6bqlA:9.17"],["4U0I_A_0LIA1001_2","MAST\/STEM CELL GROWTH FACTOR RECEPTOR KIT,MAST\/STEM CELL GROWTH FACTOR RECEPTOR KIT","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ALA A 192;LYS A 194;LEU A 240;GLY A 273;HIS A 310;LEU A 319;ASP A 330","BI9 A 501 (-3.3A);NH4 A 506 ( 4.4A);None;BI9 A 501 (-3.3A);None;BI9 A 501 (-4.7A);None","0.99A","4u0iA-6bqlA:21.6","4rz7A-6bqlA:6.87"],["4UXQ_A_0LIA1752_1","FIBROBLAST GROWTH FACTOR RECEPTOR 4","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ALA A 192;LEU A 303;HIS A 310;LEU A 319;ALA A 329","BI9 A 501 (-3.3A);None;None;BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A)","0.39A","4uxqA-6bqlA:22.0","4u0iA-6bqlA:11.73"],["4XEY_B_1N1B601_1","TYROSINE-PROTEIN KINASE ABL1","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;LYS A 194;VAL A 249;GLY A 273;LEU A 319;ALA A 329","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);NH4 A 506 ( 4.4A);None;BI9 A 501 (-3.3A);BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A)","0.66A","4xeyB-6bqlA:23.8","4uxqA-6bqlA:13.64"],["5I9Y_A_1N1A1001_1","EPHRIN TYPE-A RECEPTOR 2","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ILE A 171;ALA A 192;LYS A 194;GLU A 236;GLY A 273;LEU A 319","BI9 A 501 (-4.0A);BI9 A 501 (-3.3A);NH4 A 506 ( 4.4A);NH4 A 506 (-3.0A);BI9 A 501 (-3.3A);BI9 A 501 (-4.7A)","0.62A","5i9yA-6bqlA:23.1","4xeyB-6bqlA:13.68"],["5IZJ_G_AZ1G2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;47P-AZ1-DAR-DAR","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"GLY A 172;GLY A 174;SER A 175;VAL A 179;LYS A 194;LEU A 196","BI9 A 501 (-3.6A);None;ACT A 504 (-3.3A);BI9 A 501 ( 4.8A);NH4 A 506 ( 4.4A);None","0.60A","5izjA-6bqlA:29.2","5i9yA-6bqlA:13.91"],["5J5X_B_AZ1B2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;47P-AZ1-DAL-DAR-DAR-DAR-DAR","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"GLY A 172;GLY A 174;SER A 175;VAL A 179;LYS A 194","BI9 A 501 (-3.6A);None;ACT A 504 (-3.3A);BI9 A 501 ( 4.8A);NH4 A 506 ( 4.4A)","0.46A","5j5xA-6bqlA:29.4","5izjA-6bqlA:13.46"],["5L2I_A_LQQA900_1","CYCLIN-DEPENDENT KINASE 6","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"GLY A 172;VAL A 179;ALA A 192;VAL A 249;PHE A 267;LEU A 319;ALA A 329","BI9 A 501 (-3.6A);BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);None;BI9 A 501 ( 4.2A);BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A)","0.84A","5l2iA-6bqlA:8.0","5j5xA-6bqlA:13.46"],["5L2T_A_6ZZA900_1","CYCLIN-DEPENDENT KINASE 6","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"VAL A 179;ALA A 192;VAL A 249;PHE A 267;LEU A 319;ALA A 329","BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);None;BI9 A 501 ( 4.2A);BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A)","0.90A","5l2tA-6bqlA:8.0","5l2iA-6bqlA:13.64"],["5MO4_A_NILA601_2","TYROSINE-PROTEIN KINASE ABL1","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ALA A 192;VAL A 249;HIS A 310;LEU A 319;ALA A 329","BI9 A 501 (-3.3A);None;None;BI9 A 501 (-4.7A);NH4 A 506 ( 3.7A)","0.48A","5mo4A-6bqlA:18.8","5l2tA-6bqlA:13.64"],["5VC3_A_DB8A601_1","WEE1-LIKE PROTEIN KINASE","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ILE A 171;GLY A 172;ALA A 192;GLU A 236;GLY A 273;ASP A 330","BI9 A 501 (-4.0A);BI9 A 501 (-3.6A);BI9 A 501 (-3.3A);NH4 A 506 (-3.0A);BI9 A 501 (-3.3A);None","0.88A","5vc3A-6bqlA:26.5","5mo4A-6bqlA:10.92"],["5XV7_A_EMHA705_1","SERINE-ARGININE (SR) PROTEIN KINASE 1","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"GLY A 172;VAL A 179;ALA A 192;PHE A 267;ALA A 329","BI9 A 501 (-3.6A);BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);BI9 A 501 ( 4.2A);NH4 A 506 ( 3.7A)","0.31A","5xv7A-6bqlA:25.5","5vc3A-6bqlA:16.61"],["6FNM_A_1N1A1001_1","-","6bql","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;VAL A 179;ALA A 192;LYS A 194;GLU A 236;GLY A 273;LEU A 319","BI9 A 501 (-4.0A);BI9 A 501 ( 4.8A);BI9 A 501 (-3.3A);NH4 A 506 ( 4.4A);NH4 A 506 (-3.0A);BI9 A 501 (-3.3A);BI9 A 501 (-4.7A)","0.66A","6fnmA-6bqlA:23.9","5xv7A-6bqlA:22.35"]]