SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BEF'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C6Y_B_MK1B524_2 (PROTEIN (PROTEASE))	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 12	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.83A	1c6yB-3nnsA: undetectable	1c6yB-3nnsA: 23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C9S_T_TRPT81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	4 / 7	GLY A 289 ALA A 589 THR A 583 THR A 442	BEF  A1732 (-3.0A) None BEF  A1732 (-4.2A) None	0.77A	1c9sT-4umvA: undetectable 1c9sU-4umvA: undetectable	1c9sT-4umvA: 7.07 1c9sU-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CBS_A_REAA200_1 (CELLULAR RETINOIC ACID BINDING PROTEIN TYPE II)	5lta	PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP43 (Chaetomium thermophilum)	5 / 12	LEU A 310 ILE A 383 ALA A 384 VAL A 154 ARG A 435	None U  E   5 ( 4.2A) None None BEF  A 803 ( 2.8A)	1.06A	1cbsA-5ltaA: undetectable	1cbsA-5ltaA: 12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EII_A_RTLA135_0 (CELLULAR RETINOL-BINDING PROTEIN II)	4ldz	TRANSCRIPTIONAL REGULATORY PROTEIN DESR (Bacillus subtilis)	5 / 12	THR A 139 ILE A  78 THR A  80 LEU A 101 LEU A 131	None None BEF  A 202 (-3.7A) None None	1.22A	1eiiA-4ldzA: undetectable	1eiiA-4ldzA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1F5L_A_AMRA301_1 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	5yew	MITOFUSIN-1,MITOFUSI N-1 FUSION PROTEIN (Homo sapiens)	4 / 8	SER B  86 SER B  89 GLY B 181 GLY B  82	GDP  B 801 (-4.1A) MG  B 804 ( 2.1A) BEF  B 802 (-3.3A) None	0.73A	1f5lA-5yewB: undetectable	1f5lA-5yewB: 17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FB7_A_ROCA100_1 (HIV-1 PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 12	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.82A	1fb7A-3nnsA: undetectable	1fb7A-3nnsA: 20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GEB_A_CAMA418_0 (CYTOCHROME P450-CAM)	3hb0	EYES ABSENT HOMOLOG 2 (DROSOPHILA) (Homo sapiens)	5 / 9	THR A 447 LEU A 275 VAL A 458 ILE A 312 ILE A 452	BEF  A 801 (-3.7A) BEF  A 801 (-4.2A) None None None	1.37A	1gebA-3hb0A: undetectable	1gebA-3hb0A: 19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_L_TRPL81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	4 / 7	GLY A 289 ALA A 589 THR A 583 THR A 442	BEF  A1732 (-3.0A) None BEF  A1732 (-4.2A) None	0.77A	1gtfL-4umvA: undetectable 1gtfM-4umvA: undetectable	1gtfL-4umvA: 7.07 1gtfM-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_N_TRPN81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	4 / 8	GLY A 289 ALA A 589 THR A 583 THR A 442	BEF  A1732 (-3.0A) None BEF  A1732 (-4.2A) None	0.78A	1gtfN-4umvA: undetectable 1gtfO-4umvA: undetectable	1gtfN-4umvA: 7.07 1gtfO-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_I_TRPI81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 10	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.03A	1gtnH-4umvA: undetectable 1gtnI-4umvA: undetectable	1gtnH-4umvA: 7.07 1gtnI-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IKE_A_HSMA190_1 (NITROPHORIN 4)	1zh4	KDP OPERON TRANSCRIPTIONAL REGULATORY PROTEIN KDPE (Escherichia coli)	3 / 3	ASP A   9 LEU A  53 LEU A  55	MG  A 201 (-2.4A) BEF  A 301 (-4.7A) None	0.77A	1ikeA-1zh4A: undetectable	1ikeA-1zh4A: 20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IKE_A_HSMA190_1 (NITROPHORIN 4)	2pl1	TRANSCRIPTIONAL REGULATORY PROTEIN PHOP (Escherichia coli)	3 / 3	ASP A   8 LEU A  52 LEU A  54	MG  A 204 (-2.6A) BEF  A 205 (-4.3A) None	0.69A	1ikeA-2pl1A: undetectable	1ikeA-2pl1A: 18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IKE_A_HSMA190_1 (NITROPHORIN 4)	3w9s	OMPR FAMILY RESPONSE REGULATOR IN TWO-COMPONENT REGULATORY SYSTEM WITH BASS (Klebsiella pneumoniae)	3 / 3	ASP A   8 LEU A  52 LEU A  54	MG  A 202 (-2.6A) BEF  A 201 (-4.5A) None	0.69A	1ikeA-3w9sA: undetectable	1ikeA-3w9sA: 21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIA_C_SAMC2293_0 (GLYCINE N-METHYLTRANSFERASE)	5yew	MITOFUSIN-1,MITOFUSI N-1 FUSION PROTEIN (Homo sapiens)	5 / 12	ILE B 108 GLY B 181 ASP B 178 GLY B  87 LEU B 212	K  B 803 (-4.2A) BEF  B 802 (-3.3A) MG  B 804 ( 3.8A) GDP  B 801 (-3.6A) None	1.08A	1kiaC-5yewB: undetectable	1kiaC-5yewB: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NP1_B_HSMB304_1 (NITROPHORIN 1)	2pl1	TRANSCRIPTIONAL REGULATORY PROTEIN PHOP (Escherichia coli)	3 / 3	ASP A   8 LEU A  52 LEU A  54	MG  A 204 (-2.6A) BEF  A 205 (-4.3A) None	0.75A	1np1B-2pl1A: undetectable	1np1B-2pl1A: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NP1_B_HSMB304_1 (NITROPHORIN 1)	3w9s	OMPR FAMILY RESPONSE REGULATOR IN TWO-COMPONENT REGULATORY SYSTEM WITH BASS (Klebsiella pneumoniae)	3 / 3	ASP A   8 LEU A  52 LEU A  54	MG  A 202 (-2.6A) BEF  A 201 (-4.5A) None	0.75A	1np1B-3w9sA: undetectable	1np1B-3w9sA: 21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT2_A_SAMA301_0 (FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN)	3w9s	OMPR FAMILY RESPONSE REGULATOR IN TWO-COMPONENT REGULATORY SYSTEM WITH BASS (Klebsiella pneumoniae)	5 / 12	TYR A  98 GLY A  90 THR A  79 SER A  64 ASP A  86	None None BEF  A 201 (-3.7A) None None	1.11A	1nt2A-3w9sA: 3.6	1nt2A-3w9sA: 20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT2_A_SAMA301_0 (FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN)	4s05	DNA-BINDING TRANSCRIPTIONAL REGULATOR BASR (Klebsiella pneumoniae)	5 / 12	TYR A  98 GLY A  90 THR A  79 SER A  64 ASP A  86	None None BEF  A 301 (-3.7A) None None	0.97A	1nt2A-4s05A: undetectable	1nt2A-4s05A: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OHR_A_1UNA201_1 (ASPARTYLPROTEASE)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	5 / 11	GLY A  96 ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None None BEF  A 402 (-3.2A)	0.87A	1ohrA-3nnnA: undetectable	1ohrA-3nnnA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OHR_A_1UNA201_1 (ASPARTYLPROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 11	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.79A	1ohrA-3nnsA: undetectable	1ohrA-3nnsA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1STF_E_CCSE25_0 (PAPAIN STEFIN B (CYSTATIN B))	5sup	ATP-DEPENDENT RNA HELICASE SUB2 (Saccharomyces cerevisiae)	6 / 10	GLY A 111 PHE A 246 SER A 247 ALA A 248 SER A 108 GLY A 109	ADP  A1000 ( 3.3A) None None BEF  A1001 ( 3.9A) BEF  A1001 ( 4.2A) ADP  A1000 ( 3.2A)	0.95A	1stfE-5supA: undetectable 1stfI-5supA: undetectable	1stfE-5supA: 18.27 1stfI-5supA: 14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_A_BEZA11_0 (CES1 PROTEIN)	3hb0	EYES ABSENT HOMOLOG 2 (DROSOPHILA) (Homo sapiens)	4 / 4	LEU A 463 SER A 428 LEU A 445 LEU A 275	None None None BEF  A 801 (-4.2A)	1.14A	1yajA-3hb0A: undetectable	1yajA-3hb0A: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J0D_A_ERYA1498_0 (CYTOCHROME P450 3A4)	4tz0	ATP-DEPENDENT RNA HELICASE MSS116, MITOCHONDRIAL (Saccharomyces cerevisiae)	5 / 12	ILE A 499 ILE A 497 ALA A 338 THR A 154 ALA A 468	None None None BEF  A 602 (-4.4A) None	0.94A	2j0dA-4tz0A: undetectable	2j0dA-4tz0A: 24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NMY_A_ROCA401_1 (PROTEASE)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	5 / 12	GLY A  96 ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None None BEF  A 402 (-3.2A)	0.90A	2nmyA-3nnnA: undetectable	2nmyA-3nnnA: 18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NMY_A_ROCA401_1 (PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 12	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.86A	2nmyA-3nnsA: undetectable	2nmyA-3nnsA: 23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNP_A_ROCA401_1 (PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 11	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.93A	2nnpA-3nnsA: undetectable	2nnpA-3nnsA: 23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XCT_X_CPFX1020_1 (DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A)	5sup	ATP-DEPENDENT RNA HELICASE SUB2 (Saccharomyces cerevisiae)	4 / 4	ARG A 368 GLY A 367 GLU A 216 SER A 408	None None BEF  A1001 ( 4.0A) None	1.23A	2xctS-5supA: undetectable 2xctU-5supA: undetectable	2xctS-5supA: 21.41 2xctU-5supA: 21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7H_B_SAMB530_0 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 12	THR A 583 ILE A 581 GLY A 439 THR A 440 LEU A 477	BEF  A1732 (-4.2A) None MG  A1731 ( 4.6A) None None	0.97A	2y7hB-4umvA: undetectable	2y7hB-4umvA: 19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7H_C_SAMC530_0 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 12	THR A 583 ILE A 581 GLY A 439 THR A 440 LEU A 477	BEF  A1732 (-4.2A) None MG  A1731 ( 4.6A) None None	0.97A	2y7hC-4umvA: undetectable	2y7hC-4umvA: 19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D1X_A_ROCA201_1 (HIV-1 PROTEASE)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	5 / 12	GLY A  96 ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None None BEF  A 402 (-3.2A)	0.86A	3d1xA-3nnnA: undetectable	3d1xA-3nnnA: 18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D1X_A_ROCA201_1 (HIV-1 PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 12	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.80A	3d1xA-3nnsA: undetectable	3d1xA-3nnsA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D1Y_A_ROCA201_1 (HIV-1 PROTEASE)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	5 / 12	GLY A  96 ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None None BEF  A 402 (-3.2A)	0.87A	3d1yA-3nnnA: undetectable	3d1yA-3nnnA: 18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D1Y_A_ROCA201_1 (HIV-1 PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 12	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.81A	3d1yA-3nnsA: undetectable	3d1yA-3nnsA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKX_B_1UNB201_1 (PROTEASE)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	5 / 11	GLY A  96 ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None None BEF  A 402 (-3.2A)	0.84A	3ekxA-3nnnA: undetectable	3ekxA-3nnnA: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKX_B_1UNB201_1 (PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 11	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.78A	3ekxA-3nnsA: undetectable	3ekxA-3nnsA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL0_A_1UNA201_1 (PROTEASE)	1zes	PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB (Escherichia coli)	4 / 8	GLY A  98 ALA A  99 ASP A 100 THR A  83	None None None BEF  A 201 (-3.5A)	0.60A	3el0A-1zesA: undetectable	3el0A-1zesA: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL0_A_1UNA201_1 (PROTEASE)	2pl1	TRANSCRIPTIONAL REGULATORY PROTEIN PHOP (Escherichia coli)	4 / 8	GLY A  94 ALA A  95 ASP A  96 THR A  79	None None None BEF  A 205 (-3.5A)	0.64A	3el0A-2pl1A: undetectable	3el0A-2pl1A: 19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL0_A_1UNA201_1 (PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	4 / 8	GLY A  93 ALA A  94 ASP A  95 THR A  78	None None None BEF  A 402 (-3.6A)	0.62A	3el0A-3nnsA: undetectable	3el0A-3nnsA: 22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL0_A_1UNA201_1 (PROTEASE)	3w9s	OMPR FAMILY RESPONSE REGULATOR IN TWO-COMPONENT REGULATORY SYSTEM WITH BASS (Klebsiella pneumoniae)	4 / 8	GLY A  94 ALA A  95 ASP A  96 THR A  79	None None None BEF  A 201 (-3.7A)	0.60A	3el0A-3w9sA: undetectable	3el0A-3w9sA: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL4_A_ROCA100_1 (PROTEASE)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	5 / 12	GLY A  96 ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None None BEF  A 402 (-3.2A)	0.84A	3el4A-3nnnA: undetectable	3el4A-3nnnA: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL4_A_ROCA100_1 (PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 12	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.80A	3el4A-3nnsA: undetectable	3el4A-3nnsA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL5_B_1UNB201_2 (PROTEASE)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	5 / 12	GLY A  96 ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None None BEF  A 402 (-3.2A)	0.78A	3el5B-3nnnA: undetectable	3el5B-3nnnA: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL5_B_1UNB201_2 (PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 12	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.71A	3el5B-3nnsA: undetectable	3el5B-3nnsA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL9_A_DR7A100_1 (PROTEASE)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	4 / 8	ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None BEF  A 402 (-3.2A)	0.84A	3el9A-3nnnA: undetectable	3el9A-3nnnA: 18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA151_0 (ILEAL BILE ACID-BINDING PROTEIN)	4ldz	TRANSCRIPTIONAL REGULATORY PROTEIN DESR (Bacillus subtilis)	4 / 7	ILE A  55 GLY A  86 VAL A  96 LEU A 101	BEF  A 202 (-3.6A) None None None	0.93A	3elzA-4ldzA: undetectable	3elzA-4ldzA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G88_A_SAMA303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 11	GLY A 627 GLY A 629 ASP A 628 THR A 438 ALA A 635	None MG  A1731 (-4.1A) MG  A1731 ( 1.1A) BEF  A1732 ( 3.7A) None	1.04A	3g88A-4umvA: undetectable	3g88A-4umvA: 20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G88_B_SAMB303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 11	GLY A 627 GLY A 629 ASP A 628 THR A 438 ALA A 635	None MG  A1731 (-4.1A) MG  A1731 ( 1.1A) BEF  A1732 ( 3.7A) None	1.03A	3g88B-4umvA: 3.6	3g88B-4umvA: 20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G89_A_SAMA303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 12	GLY A 627 GLY A 629 ASP A 628 THR A 438 ALA A 635	None MG  A1731 (-4.1A) MG  A1731 ( 1.1A) BEF  A1732 ( 3.7A) None	1.02A	3g89A-4umvA: undetectable	3g89A-4umvA: 20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G89_B_SAMB303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 11	GLY A 627 GLY A 629 ASP A 628 THR A 438 ALA A 635	None MG  A1731 (-4.1A) MG  A1731 ( 1.1A) BEF  A1732 ( 3.7A) None	1.02A	3g89B-4umvA: undetectable	3g89B-4umvA: 20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8B_A_SAMA303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 12	GLY A 627 GLY A 629 ASP A 628 THR A 438 ALA A 635	None MG  A1731 (-4.1A) MG  A1731 ( 1.1A) BEF  A1732 ( 3.7A) None	1.02A	3g8bA-4umvA: undetectable	3g8bA-4umvA: 20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8B_B_SAMB303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 12	GLY A 627 GLY A 629 ASP A 628 THR A 438 ALA A 635	None MG  A1731 (-4.1A) MG  A1731 ( 1.1A) BEF  A1732 ( 3.7A) None	1.00A	3g8bB-4umvA: undetectable	3g8bB-4umvA: 20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IJD_B_C2FB314_1 (UNCHARACTERIZED PROTEIN)	5bq5	INSERTION SEQUENCE IS5376 PUTATIVE ATP-BINDING PROTEIN (Geobacillus stearothermophil us)	3 / 3	THR A 112 LYS A 153 GLU A 167	MG  A 302 ( 3.1A) None BEF  A 303 ( 4.9A)	1.02A	3ijdB-5bq5A: undetectable	3ijdB-5bq5A: 22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N2O_C_AG2C1002_1 (BIOSYNTHETIC ARGININE DECARBOXYLASE)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	4 / 8	SER A 285 ASP A 559 ASP A 628 ASP A 436	None None MG  A1731 ( 1.1A) BEF  A1732 ( 2.0A)	0.91A	3n2oC-4umvA: undetectable 3n2oD-4umvA: undetectable	3n2oC-4umvA: 21.35 3n2oD-4umvA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PP7_B_SVRB499_1 (PYRUVATE KINASE)	1nne	DNA MISMATCH REPAIR PROTEIN MUTS (Thermus aquaticus)	5 / 10	ASN A 585 HIS A 696 TYR A 737 GLY A 588 ALA A 587	BEF  A 998 (-3.4A) SO4  A 852 (-4.3A) None ADP  A 999 (-3.4A) ADP  A 999 (-4.4A)	1.46A	3pp7B-1nneA: undetectable	3pp7B-1nneA: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S56_A_ROCA201_1 (PROTEASE)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	5 / 12	GLY A  96 ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None None BEF  A 402 (-3.2A)	0.92A	3s56A-3nnnA: undetectable	3s56A-3nnnA: 17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S56_A_ROCA201_1 (PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 12	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.82A	3s56A-3nnsA: undetectable	3s56A-3nnsA: 23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_C_ROCC901_1 (PROTEASE)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	5 / 12	GLY A  96 ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None None BEF  A 402 (-3.2A)	0.78A	3tkgC-3nnnA: undetectable	3tkgC-3nnnA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_C_ROCC901_1 (PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 12	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.68A	3tkgC-3nnsA: undetectable	3tkgC-3nnsA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFN_A_ROCA401_1 (HIV-1 PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 11	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.82A	3ufnA-3nnsA: undetectable	3ufnA-3nnsA: 23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VNS_A_DVAA602_0 (NRPS ADENYLATION PROTEIN CYTC1)	5dxi	TREHALOSE-6-PHOSPHAT E PHOSPHATASE (Candida albicans)	4 / 7	ASP A 230 GLY A  66 THR A  29 LYS A 188	MG  A 401 (-2.6A) TRE  A 403 ( 3.4A) None BEF  A 402 (-2.7A)	1.07A	3vnsA-5dxiA: undetectable	3vnsA-5dxiA: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAN_B_2FAB301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	5lta	PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP43 (Chaetomium thermophilum)	5 / 12	ARG A 432 GLY A 119 VAL A 118 GLU A 219 SER A 123	BEF  A 803 (-2.9A) None None BEF  A 803 (-3.6A) ADP  A 801 (-4.5A)	1.16A	4danA-5ltaA: undetectable 4danB-5ltaA: undetectable	4danA-5ltaA: 15.47 4danB-5ltaA: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KIC_B_SAMB401_1 (METHYLTRANSFERASE MPPJ)	6ftx	- (-)	3 / 3	ARG W 804 ASP W 798 ASP W 790	BEF  W1301 (-3.6A) None None	0.80A	4kicB-6ftxW: undetectable	4kicB-6ftxW: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KM0_A_CP6A201_1 (DIHYDROFOLATE REDUCTASE)	5dxi	TREHALOSE-6-PHOSPHAT E PHOSPHATASE (Candida albicans)	5 / 10	ILE A  64 ASP A 234 LEU A  46 ILE A  63 THR A 233	None MG  A 401 ( 4.2A) None None BEF  A 402 ( 4.6A)	1.24A	4km0A-5dxiA: 2.5	4km0A-5dxiA: 20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LJ0_A_ACTA505_0 (NAB2)	4if4	RESPONSE REGULATOR PROTEIN VRAR (Staphylococcus aureus)	3 / 3	LEU A 104 LYS A 105 THR A 106	None BEF  A 301 (-2.8A) None	0.59A	4lj0A-4if4A: undetectable	4lj0A-4if4A: 14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJT_D_017D101_2 (PROTEASE)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	5 / 9	GLY A  96 ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None None BEF  A 402 (-3.2A)	1.12A	4njtD-3nnnA: undetectable	4njtD-3nnnA: 16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJT_D_017D101_2 (PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 9	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	1.10A	4njtD-3nnsA: undetectable	4njtD-3nnsA: 22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJV_D_RITD500_2 (PROTEASE)	4s05	DNA-BINDING TRANSCRIPTIONAL REGULATOR BASR (Klebsiella pneumoniae)	5 / 12	GLY A  94 ALA A  95 ILE A  48 THR A  79 ILE A  77	None None None BEF  A 301 (-3.7A) None	1.12A	4njvD-4s05A: undetectable	4njvD-4s05A: 18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QGI_A_ROCA101_1 (PROTEASE)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	5 / 11	GLY A  96 ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None None BEF  A 402 (-3.2A)	0.88A	4qgiA-3nnnA: undetectable	4qgiA-3nnnA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QGI_A_ROCA101_1 (PROTEASE)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 11	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.79A	4qgiA-3nnsA: undetectable	4qgiA-3nnsA: 20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XJE_A_TOYA202_1 (AADB)	4d6y	BACTERIAL REGULATORY, FIS FAMILY PROTEIN (Brucella abortus)	4 / 8	ASP A  10 ASP A  53 ASP A   9 ILE A 103	MG  A1126 (-2.6A) BEF  A1125 ( 2.2A) MG  A1126 ( 4.1A) None	1.00A	4xjeA-4d6yA: undetectable	4xjeA-4d6yA: 24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XJE_A_TOYA202_1 (AADB)	4hns	CHEMOTAXIS PROTEIN CHEY (Vibrio cholerae)	4 / 8	ASP A  16 ASP A  60 ASP A  15 ILE A 110	MG  A 201 (-2.6A) BEF  A 202 ( 2.0A) MG  A 201 ( 4.3A) None	1.03A	4xjeA-4hnsA: undetectable	4xjeA-4hnsA: 24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTA_G_MFXG101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	5elx	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	4 / 7	SER A 438 ARG A 429 GLY A 428 THR A 142	None BEF  A 503 ( 2.6A) None M2A  A 501 (-4.5A)	0.97A	5btaA-5elxA: undetectable 5btaC-5elxA: undetectable 5btaD-5elxA: 2.0	5btaA-5elxA: 22.65 5btaC-5elxA: 22.65 5btaD-5elxA: 20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTA_H_MFXH101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCAC GTAA)	5elx	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	4 / 6	SER A 438 ARG A 429 GLY A 428 THR A 142	None BEF  A 503 ( 2.6A) None M2A  A 501 (-4.5A)	0.97A	5btaA-5elxA: undetectable 5btaB-5elxA: 2.5 5btaC-5elxA: undetectable	5btaA-5elxA: 22.65 5btaB-5elxA: 20.96 5btaC-5elxA: 22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTC_G_CPFG101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	5elx	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	4 / 6	SER A 438 ARG A 429 GLY A 428 THR A 142	None BEF  A 503 ( 2.6A) None M2A  A 501 (-4.5A)	1.00A	5btcA-5elxA: undetectable 5btcC-5elxA: undetectable 5btcD-5elxA: 2.0	5btcA-5elxA: 22.65 5btcC-5elxA: 22.65 5btcD-5elxA: 20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTC_G_CPFG102_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	5elx	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	4 / 6	SER A 438 ARG A 429 GLY A 428 THR A 142	None BEF  A 503 ( 2.6A) None M2A  A 501 (-4.5A)	1.01A	5btcA-5elxA: undetectable 5btcB-5elxA: 2.5 5btcC-5elxA: undetectable	5btcA-5elxA: 22.65 5btcB-5elxA: 20.96 5btcC-5elxA: 22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CFS_A_TOYA203_1 (AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANS FERASE,GENTAMICIN RESISTANCE PROTEIN)	4d6y	BACTERIAL REGULATORY, FIS FAMILY PROTEIN (Brucella abortus)	4 / 8	ASP A  10 ASP A  53 ASP A   9 ILE A 103	MG  A1126 (-2.6A) BEF  A1125 ( 2.2A) MG  A1126 ( 4.1A) None	1.01A	5cfsA-4d6yA: undetectable	5cfsA-4d6yA: 24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CFS_A_TOYA203_1 (AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANS FERASE,GENTAMICIN RESISTANCE PROTEIN)	4hns	CHEMOTAXIS PROTEIN CHEY (Vibrio cholerae)	4 / 8	ASP A  16 ASP A  60 ASP A  15 ILE A 110	MG  A 201 (-2.6A) BEF  A 202 ( 2.0A) MG  A 201 ( 4.3A) None	1.00A	5cfsA-4hnsA: undetectable	5cfsA-4hnsA: 24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECL_A_ILEA602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	4s05	DNA-BINDING TRANSCRIPTIONAL REGULATOR BASR (Klebsiella pneumoniae)	4 / 6	ALA A  80 THR A  79 VAL A 100 TYR A  98	BEF  A 301 (-3.5A) BEF  A 301 (-3.7A) None None	1.05A	5eclA-4s05A: 1.9	5eclA-4s05A: 18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_A_LEUA602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	4hns	CHEMOTAXIS PROTEIN CHEY (Vibrio cholerae)	4 / 6	ALA A  91 THR A  90 VAL A 111 TYR A 109	BEF  A 202 (-3.8A) BEF  A 202 (-3.4A) None None	0.92A	5ecoA-4hnsA: 2.9	5ecoA-4hnsA: 14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_A_LEUA602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	4s05	DNA-BINDING TRANSCRIPTIONAL REGULATOR BASR (Klebsiella pneumoniae)	4 / 6	ALA A  80 THR A  79 VAL A 100 TYR A  98	BEF  A 301 (-3.5A) BEF  A 301 (-3.7A) None None	0.94A	5ecoA-4s05A: 2.4	5ecoA-4s05A: 18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEU_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 10	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.03A	5eeuF-4umvA: undetectable 5eeuG-4umvA: undetectable	5eeuF-4umvA: 7.07 5eeuG-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEU_I_TRPI101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 12	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.03A	5eeuI-4umvA: undetectable 5eeuJ-4umvA: undetectable	5eeuI-4umvA: 7.07 5eeuJ-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 10	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.03A	5eevF-4umvA: undetectable 5eevG-4umvA: undetectable	5eevF-4umvA: 7.07 5eevG-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_I_TRPI101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 12	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.03A	5eevI-4umvA: undetectable 5eevJ-4umvA: undetectable	5eevI-4umvA: 7.07 5eevJ-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 10	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.04A	5eewF-4umvA: undetectable 5eewG-4umvA: undetectable	5eewF-4umvA: 7.07 5eewG-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_I_TRPI101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 12	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.03A	5eewI-4umvA: undetectable 5eewJ-4umvA: undetectable	5eewI-4umvA: 7.07 5eewJ-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEX_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 10	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.03A	5eexF-4umvA: undetectable 5eexG-4umvA: undetectable	5eexF-4umvA: 7.07 5eexG-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEY_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 10	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.04A	5eeyF-4umvA: undetectable 5eeyG-4umvA: undetectable	5eeyF-4umvA: 7.07 5eeyG-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEZ_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 10	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.04A	5eezF-4umvA: undetectable 5eezG-4umvA: undetectable	5eezF-4umvA: 7.07 5eezG-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEZ_L_TRPL101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	4 / 8	THR A 442 GLY A 289 ALA A 589 THR A 583	None BEF  A1732 (-3.0A) None BEF  A1732 (-4.2A)	0.81A	5eezL-4umvA: undetectable 5eezV-4umvA: undetectable	5eezL-4umvA: 7.07 5eezV-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF0_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 10	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.04A	5ef0F-4umvA: undetectable 5ef0G-4umvA: undetectable	5ef0F-4umvA: 7.07 5ef0G-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF1_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 10	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.04A	5ef1F-4umvA: undetectable 5ef1G-4umvA: undetectable	5ef1F-4umvA: 7.07 5ef1G-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF1_L_TRPL101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	4 / 8	THR A 442 GLY A 289 ALA A 589 THR A 583	None BEF  A1732 (-3.0A) None BEF  A1732 (-4.2A)	0.80A	5ef1L-4umvA: undetectable 5ef1V-4umvA: undetectable	5ef1L-4umvA: 7.07 5ef1V-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF2_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 10	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.04A	5ef2F-4umvA: undetectable 5ef2G-4umvA: undetectable	5ef2F-4umvA: 7.07 5ef2G-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF2_L_TRPL101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	4 / 8	THR A 442 GLY A 289 ALA A 589 THR A 583	None BEF  A1732 (-3.0A) None BEF  A1732 (-4.2A)	0.80A	5ef2L-4umvA: undetectable 5ef2V-4umvA: undetectable	5ef2L-4umvA: 7.07 5ef2V-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF3_F_TRPF101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	4umv	ZINC-TRANSPORTING ATPASE (Shigella sonnei)	5 / 10	ALA A 589 GLY A 289 ALA A 590 THR A 442 THR A 438	None BEF  A1732 (-3.0A) None None BEF  A1732 ( 3.7A)	1.04A	5ef3F-4umvA: undetectable 5ef3G-4umvA: undetectable	5ef3F-4umvA: 7.07 5ef3G-4umvA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IAO_C_URFC301_1 (BIFUNCTIONAL PROTEIN PYRR)	4tz0	ATP-DEPENDENT RNA HELICASE MSS116, MITOCHONDRIAL (Saccharomyces cerevisiae)	3 / 3	ARG A 469 HIS A 462 ARG A 466	BEF  A 602 ( 2.6A) None BEF  A 602 (-3.0A)	1.11A	5iaoC-4tz0A: 2.6	5iaoC-4tz0A: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IAO_C_URFC301_1 (BIFUNCTIONAL PROTEIN PYRR)	5elx	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	3 / 3	ARG A 429 HIS A 422 ARG A 426	BEF  A 503 ( 2.6A) None BEF  A 503 (-2.7A)	1.12A	5iaoC-5elxA: 3.4	5iaoC-5elxA: 18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IAO_F_URFF301_1 (BIFUNCTIONAL PROTEIN PYRR)	4tz0	ATP-DEPENDENT RNA HELICASE MSS116, MITOCHONDRIAL (Saccharomyces cerevisiae)	3 / 3	ARG A 469 HIS A 462 ARG A 466	BEF  A 602 ( 2.6A) None BEF  A 602 (-3.0A)	1.15A	5iaoF-4tz0A: 2.5	5iaoF-4tz0A: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IAO_F_URFF301_1 (BIFUNCTIONAL PROTEIN PYRR)	5elx	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	3 / 3	ARG A 429 HIS A 422 ARG A 426	BEF  A 503 ( 2.6A) None BEF  A 503 (-2.7A)	1.15A	5iaoF-5elxA: 3.4	5iaoF-5elxA: 18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KQX_A_ROCA101_1 (PROTEASE E35D-SQV)	3nnn	DNA BINDING RESPONSE REGULATOR D (Thermotoga maritima)	5 / 12	GLY A  96 ALA A  97 ASP A  98 ILE A  64 THR A  81	None None None None BEF  A 402 (-3.2A)	0.87A	5kqxA-3nnnA: undetectable	5kqxA-3nnnA: 19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KQX_A_ROCA101_1 (PROTEASE E35D-SQV)	3nns	DNA BINDING RESPONSE REGULATOR B (Thermotoga maritima)	5 / 12	GLY A  93 ALA A  94 ASP A  95 ILE A  61 THR A  78	None None None None BEF  A 402 (-3.6A)	0.83A	5kqxA-3nnsA: undetectable	5kqxA-3nnsA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VIM_A_SAMA301_1 (METHYLTRANSFERASE)	5dxi	TREHALOSE-6-PHOSPHAT E PHOSPHATASE (Candida albicans)	4 / 4	SER A  65 THR A 138 ASP A 115 ASP A  68	BEF  A 402 ( 2.4A) TRE  A 403 ( 3.9A) None None	1.44A	5vimA-5dxiA: undetectable	5vimA-5dxiA: 23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VIM_B_SAMB301_1 (METHYLTRANSFERASE)	5dxi	TREHALOSE-6-PHOSPHAT E PHOSPHATASE (Candida albicans)	4 / 4	SER A  65 THR A 138 ASP A 115 ASP A  68	BEF  A 402 ( 2.4A) TRE  A 403 ( 3.9A) None None	1.46A	5vimB-5dxiA: undetectable	5vimB-5dxiA: 23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AZ3_1_PAR11803_1 (RRNA ALPHA RIBOSOMAL PROTEIN EL18)	5yew	MITOFUSIN-1,MITOFUSI N-1 FUSION PROTEIN (Homo sapiens)	3 / 3	SER B  89 LYS B  88 SER B  90	MG  B 804 ( 2.1A) BEF  B 802 ( 2.5A) GDP  B 801 (-2.5A)	0.83A	6az3P-5yewB: undetectable	6az3P-5yewB: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWD_B_GLYB709_0 (DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1)	4tz0	ATP-DEPENDENT RNA HELICASE MSS116, MITOCHONDRIAL (Saccharomyces cerevisiae)	4 / 5	GLY A 436 ASP A 434 ARG A 466 ARG A 463	None A  B   3 ( 4.5A) BEF  A 602 (-3.0A) None	1.33A	6dwdB-4tz0A: undetectable 6dwdD-4tz0A: undetectable	6dwdB-4tz0A: 22.00 6dwdD-4tz0A: 22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWJ_B_GLYB710_0 (DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1)	4tz0	ATP-DEPENDENT RNA HELICASE MSS116, MITOCHONDRIAL (Saccharomyces cerevisiae)	4 / 5	ARG A 466 ARG A 463 GLY A 436 ASP A 434	BEF  A 602 (-3.0A) None None A  B   3 ( 4.5A)	1.34A	6dwjB-4tz0A: undetectable 6dwjD-4tz0A: undetectable	6dwjB-4tz0A: 22.00 6dwjD-4tz0A: 22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_F_TA1F502_2 (TUBULIN BETA CHAIN)	3w9s	OMPR FAMILY RESPONSE REGULATOR IN TWO-COMPONENT REGULATORY SYSTEM WITH BASS (Klebsiella pneumoniae)	4 / 5	LEU A 108 LEU A  12 THR A  79 PRO A  55	None None BEF  A 201 (-3.7A) None	1.01A	6ew0F-3w9sA: undetectable	6ew0F-3w9sA: 19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_G_TA1G501_2 (TUBULIN BETA CHAIN)	3w9s	OMPR FAMILY RESPONSE REGULATOR IN TWO-COMPONENT REGULATORY SYSTEM WITH BASS (Klebsiella pneumoniae)	4 / 6	LEU A 108 LEU A  12 THR A  79 PRO A  55	None None BEF  A 201 (-3.7A) None	1.01A	6ew0G-3w9sA: undetectable	6ew0G-3w9sA: 19.08