SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BDF'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXD_A_ACRA732_1 (ALPHA AMYLASE)	5vdn	GLUTATHIONE OXIDOREDUCTASE (Yersinia pestis)	5 / 9	GLY A 56 GLY A 151 GLY A 150 ASP A 313 ARG A 273	FAD A 502 (-3.5A) BDF A 503 (-4.9A) FAD A 502 (-3.3A) FAD A 502 (-2.9A) BDF A 503 ( 3.6A)	1.07A	1mxdA-5vdnA: undetectable	1mxdA-5vdnA: 21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXG_A_ACRA442_1 (ALPHA AMYLASE)	5vdn	GLUTATHIONE OXIDOREDUCTASE (Yersinia pestis)	5 / 11	GLY A 56 GLY A 151 GLY A 150 ASP A 313 ARG A 273	FAD A 502 (-3.5A) BDF A 503 (-4.9A) FAD A 502 (-3.3A) FAD A 502 (-2.9A) BDF A 503 ( 3.6A)	1.06A	1mxgA-5vdnA: undetectable	1mxgA-5vdnA: 21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKW_B_DR7B100_1 (PROTEASE)	5vdn	GLUTATHIONE OXIDOREDUCTASE (Yersinia pestis)	5 / 10	ASP A 168 ILE A 165 ILE A 271 ALA A 193 ILE A 192	BDF A 503 (-3.0A) None None None None	0.93A	3ekwA-5vdnA: undetectable	3ekwA-5vdnA: 13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5u9c	DTDP-4-DEHYDRORHAMNO SE REDUCTASE (Yersinia enterocolitica)	3 / 3	ARG A 186 PHE A 223 PHE A 247	None None BDF A 301 ( 3.7A)	1.03A	6nknC-5u9cA: undetectable 6nknJ-5u9cA: undetectable	6nknC-5u9cA: 19.59 6nknJ-5u9cA: 14.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MXD_A_ACRA732_1","ALPHA AMYLASE","5vdn","GLUTATHIONE OXIDOREDUCTASE","Yersinia pestis",5,"GLY A  56;GLY A 151;GLY A 150;ASP A 313;ARG A 273","FAD A 502 (-3.5A);BDF A 503 (-4.9A);FAD A 502 (-3.3A);FAD A 502 (-2.9A);BDF A 503 ( 3.6A)","1.07A","1mxdA-5vdnA:undetectable",null],["1MXG_A_ACRA442_1","ALPHA AMYLASE","5vdn","GLUTATHIONE OXIDOREDUCTASE","Yersinia pestis",5,"GLY A  56;GLY A 151;GLY A 150;ASP A 313;ARG A 273","FAD A 502 (-3.5A);BDF A 503 (-4.9A);FAD A 502 (-3.3A);FAD A 502 (-2.9A);BDF A 503 ( 3.6A)","1.06A","1mxgA-5vdnA:undetectable","1mxdA-5vdnA:21.64"],["3EKW_B_DR7B100_1","PROTEASE;PROTEASE","5vdn","GLUTATHIONE OXIDOREDUCTASE","Yersinia pestis",5,"ASP A 168;ILE A 165;ILE A 271;ALA A 193;ILE A 192","BDF A 503 (-3.0A);None;None;None;None","0.93A","3ekwA-5vdnA:undetectable","1mxgA-5vdnA:21.64"],["6NKN_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5u9c","DTDP-4-DEHYDRORHAMNOSE REDUCTASE","Yersinia enterocolitica",3,"ARG A 186;PHE A 223;PHE A 247","None;None;BDF A 301 ( 3.7A)","1.03A","6nknC-5u9cA:undetectable;6nknJ-5u9cA:undetectable","3ekwA-5vdnA:13.82"]]