SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BCT'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 7 HIS A 165
HIS A 167
HIS A 184
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.32A 1am6A-4xz5A:
29.7		 1am6A-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		4 / 7 HIS A 184
HIS A 165
HIS A 167
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
BCT  A 402 ( 4.4A)
 1.09A 1am6A-4xz5A:
29.7		 1am6A-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 8 HIS A 165
HIS A 167
HIS A 184
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.31A 1azmA-4xz5A:
29.3		 1azmA-4xz5A:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 8 HIS A 165
HIS A 167
HIS A 184
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.28A 1bzmA-4xz5A:
29.4		 1bzmA-4xz5A:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 8 HIS A 167
HIS A 184
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 1.50A 1bzmA-4xz5A:
29.4		 1bzmA-4xz5A:
34.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 2d3i OVOTRANSFERRIN
(Gallus
gallus) 		3 / 3 ALA A 462
VAL A 465
TRP A 464
 BCT  A 690 (-3.2A)
None
None
 0.85A 1c4dA-2d3iA:
undetectable
1c4dB-2d3iA:
undetectable		 1c4dA-2d3iA:
4.57
1c4dB-2d3iA:
4.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 10 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.93A 1c9sN-4yswA:
undetectable
1c9sO-4yswA:
undetectable		 1c9sN-4yswA:
5.06
1c9sO-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 11 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.91A 1c9sP-4yswA:
undetectable
1c9sQ-4yswA:
undetectable		 1c9sP-4yswA:
5.06
1c9sQ-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 10 GLY A 915
GLY A1006
HIS A 884
ALA A1079
ILE A1007
 BCT  A3006 (-3.9A)
None
None
URC  A3007 (-3.4A)
None
 0.91A 1c9sL-4yswA:
undetectable
1c9sV-4yswA:
undetectable		 1c9sL-4yswA:
5.06
1c9sV-4yswA:
5.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 HIS A 140
GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.29A 1cilA-4xz5A:
29.7		 1cilA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.03A 1cilA-4xz5A:
29.7		 1cilA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 11 HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 194
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.43A 1dmyA-4xz5A:
26.5		 1dmyA-4xz5A:
34.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
VAL A 196
LEU A 194
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.32A 1dmyA-4xz5A:
26.5		 1dmyA-4xz5A:
34.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 HIS A 184
HIS A 165
HIS A 167
TYR A 247
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 ( 4.4A)
 1.14A 1dmyA-4xz5A:
26.5		 1dmyA-4xz5A:
34.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 GLN A 143
HIS A 167
VAL A 186
LEU A 251
THR A 253
 None
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.21A 1dmyB-4xz5A:
26.5		 1dmyB-4xz5A:
34.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 12 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.34A 1dmyB-4xz5A:
26.5		 1dmyB-4xz5A:
34.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 165
HIS A 167
VAL A 186
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.00A 1dmyB-4xz5A:
26.5		 1dmyB-4xz5A:
34.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 HIS A 184
HIS A 165
HIS A 167
TYR A 247
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 ( 4.4A)
 1.13A 1dmyB-4xz5A:
26.5		 1dmyB-4xz5A:
34.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  78
SER A  79
SER A 126
LYS A 216
GLY A 218
ARG A 259
 None
KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.4A)
BCT  A 301 (-3.0A)
 0.61A 1ghmA-4k0xA:
18.1		 1ghmA-4k0xA:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 11 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.92A 1gtfQ-4yswA:
undetectable
1gtfR-4yswA:
undetectable		 1gtfQ-4yswA:
5.06
1gtfR-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 11 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.92A 1gtfS-4yswA:
undetectable
1gtfT-4yswA:
undetectable		 1gtfS-4yswA:
5.06
1gtfT-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 11 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.94A 1gtnT-4yswA:
undetectable
1gtnU-4yswA:
undetectable		 1gtnT-4yswA:
5.06
1gtnU-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 12 GLY A 915
GLY A1006
HIS A 884
ALA A1079
ILE A1007
 BCT  A3006 (-3.9A)
None
None
URC  A3007 (-3.4A)
None
 0.93A 1gtnL-4yswA:
undetectable
1gtnV-4yswA:
undetectable		 1gtnL-4yswA:
5.06
1gtnV-4yswA:
5.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 9 GLN A 143
HIS A 165
HIS A 167
HIS A 184
THR A 252
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.95A 1jd0A-4xz5A:
29.6		 1jd0A-4xz5A:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 9 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.44A 1jd0A-4xz5A:
29.6		 1jd0A-4xz5A:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.87A 1jd0A-4xz5A:
29.6		 1jd0A-4xz5A:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 GLN A 143
HIS A 165
HIS A 167
GLU A 171
HIS A 184
THR A 252
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.96A 1jd0B-4xz5A:
29.4		 1jd0B-4xz5A:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
THR A 252
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.16A 1jd0B-4xz5A:
29.4		 1jd0B-4xz5A:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.45A 1jd0B-4xz5A:
29.4		 1jd0B-4xz5A:
32.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.48A 1jd0B-4xz5A:
29.4		 1jd0B-4xz5A:
32.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 4q2h PROLINE RACEMASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 10 THR A 257
GLY A 173
VAL A 147
ALA A  91
ILE A 222
 BCT  A 401 (-2.8A)
None
None
None
None
 0.92A 1likA-4q2hA:
undetectable		 1likA-4q2hA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 2ist RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE D
(Escherichia
coli) 		5 / 8 ILE A  86
LEU A  84
ILE A  96
VAL A 148
ILE A  94
 None
BCT  A 804 (-4.2A)
None
None
None
 1.47A 1linA-2istA:
undetectable		 1linA-2istA:
19.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 ASN A 138
HIS A 167
LEU A 251
THR A 252
PRO A 255
 None
ZN  A 401 ( 3.3A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.96A 1oq5A-4xz5A:
29.7		 1oq5A-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 12 GLN A 163
HIS A 165
HIS A 167
VAL A 186
LEU A 251
THR A 252
PRO A 255
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
None
 0.38A 1oq5A-4xz5A:
29.7		 1oq5A-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 HIS A 167
VAL A 196
LEU A 251
THR A 252
PRO A 255
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 1.04A 1oq5A-4xz5A:
29.7		 1oq5A-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.40A 1rj6A-4xz5A:
29.6		 1rj6A-4xz5A:
31.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
HIS A 165
THR A 253
THR A 252
TRP A  78
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.2A)
BCT  A 402 ( 4.4A)
BCT  A 402 (-3.7A)
None
 1.41A 1rj6A-4xz5A:
29.6		 1rj6A-4xz5A:
31.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 184
HIS A 165
HIS A 167
LEU A 110
THR A 252
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.7A)
 1.36A 1rj6A-4xz5A:
29.6		 1rj6A-4xz5A:
31.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.42A 1rj6A-4xz5A:
29.6		 1rj6A-4xz5A:
31.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.40A 1rj6B-4xz5A:
29.3		 1rj6B-4xz5A:
31.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
HIS A 165
THR A 253
THR A 252
TRP A  78
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.2A)
BCT  A 402 ( 4.4A)
BCT  A 402 (-3.7A)
None
 1.41A 1rj6B-4xz5A:
29.3		 1rj6B-4xz5A:
31.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.42A 1rj6B-4xz5A:
29.3		 1rj6B-4xz5A:
31.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S2A_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		5 / 12 TRP A  90
HIS A 121
GLU A 190
TYR A 214
SER A 215
 None
BCT  A1322 ( 3.9A)
None
NDP  A1321 (-3.3A)
NDP  A1321 (-2.7A)
 0.26A 1s2aA-2bgsA:
39.7		 1s2aA-2bgsA:
33.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 12 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.94A 1utdO-4yswA:
undetectable
1utdP-4yswA:
undetectable		 1utdO-4yswA:
5.06
1utdP-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 11 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.93A 1utdP-4yswA:
undetectable
1utdQ-4yswA:
undetectable		 1utdP-4yswA:
5.06
1utdQ-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 11 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.92A 1utdS-4yswA:
undetectable
1utdT-4yswA:
undetectable		 1utdS-4yswA:
5.06
1utdT-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		5 / 10 GLY A1006
HIS A 884
ALA A1079
ILE A1007
GLY A 915
 None
None
URC  A3007 (-3.4A)
None
BCT  A3006 (-3.9A)
 0.95A 1utdU-4yswA:
undetectable
1utdV-4yswA:
undetectable		 1utdU-4yswA:
5.06
1utdV-4yswA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 3v7p AMIDOHYDROLASE
FAMILY PROTEIN
(Nitratiruptor
sp.
SB155-2) 		5 / 12 ILE A 341
ALA A 346
LEU A 293
ILE A 296
HIS A 278
 None
None
BCT  A 435 (-3.9A)
None
None
 1.22A 1xzxX-3v7pA:
undetectable		 1xzxX-3v7pA:
20.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 10 GLN A 163
HIS A 165
HIS A 184
VAL A 186
VAL A 196
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.37A 1ydaA-4xz5A:
29.2		 1ydaA-4xz5A:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 11 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.30A 1ydbA-4xz5A:
29.3		 1ydbA-4xz5A:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 HIS A 167
HIS A 184
VAL A 196
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.91A 1ydbA-4xz5A:
29.3		 1ydbA-4xz5A:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 GLN A 143
HIS A 167
VAL A 186
THR A 252
THR A 253
 None
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.17A 1yddA-4xz5A:
29.7		 1yddA-4xz5A:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
THR A 252
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.27A 1yddA-4xz5A:
29.7		 1yddA-4xz5A:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 12 GLN A 163
HIS A 165
HIS A 167
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.35A 1z9yA-4xz5A:
29.6		 1z9yA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 ASN A 138
GLN A 143
HIS A 167
VAL A 186
THR A 253
 None
None
ZN  A 401 ( 3.3A)
None
BCT  A 402 ( 4.4A)
 1.29A 1zgfA-4xz5A:
29.6		 1zgfA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 ASN A 138
HIS A 167
VAL A 186
LEU A 251
THR A 252
THR A 253
 None
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.00A 1zgfA-4xz5A:
29.6		 1zgfA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 12 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.31A 1zgfA-4xz5A:
29.6		 1zgfA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
HIS A 184
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.47A 1zgfA-4xz5A:
29.6		 1zgfA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 GLN A 143
HIS A 165
HIS A 167
GLU A 171
HIS A 184
THR A 252
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.99A 1zsbA-4xz5A:
29.8		 1zsbA-4xz5A:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 GLN A 143
HIS A 167
GLU A 171
VAL A 186
THR A 252
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.16A 1zsbA-4xz5A:
29.8		 1zsbA-4xz5A:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.38A 1zsbA-4xz5A:
29.8		 1zsbA-4xz5A:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 12 GLN A 163
HIS A 165
HIS A 167
VAL A 186
LEU A 194
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.31A 2aw1A-4xz5A:
29.6		 2aw1A-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
VAL A 196
LEU A 194
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.30A 2aw1A-4xz5A:
29.6		 2aw1A-4xz5A:
32.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 2d3i OVOTRANSFERRIN
(Gallus
gallus) 		5 / 8 TYR A 431
GLY A 523
GLY A 463
THR A 461
ALA A 462
 AL  A 689 ( 4.2A)
None
BCT  A 690 (-3.9A)
BCT  A 690 (-4.3A)
BCT  A 690 (-3.2A)
 1.33A 2ej3C-2d3iA:
undetectable		 2ej3C-2d3iA:
16.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		4 / 6 TRP A  78
GLN A 163
THR A 253
PRO A 255
 None
None
BCT  A 402 ( 4.4A)
None
 0.47A 2ez7A-4xz5A:
29.4		 2ez7A-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 8 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.34A 2gehA-4xz5A:
29.6		 2gehA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		4 / 8 HIS A 167
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 0.92A 2gehA-4xz5A:
29.6		 2gehA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 GLN A 143
HIS A 167
HIS A 184
THR A 252
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.01A 2h4nA-4xz5A:
29.8		 2h4nA-4xz5A:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 9 GLN A 163
HIS A 167
HIS A 184
VAL A 186
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.49A 2h4nA-4xz5A:
29.8		 2h4nA-4xz5A:
32.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		4 / 6 ASN A 138
HIS A 140
GLN A 163
THR A 253
 None
None
None
BCT  A 402 ( 4.4A)
 0.38A 2hkkA-4xz5A:
29.4		 2hkkA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2INE_A_PACA317_0
(ALDOSE REDUCTASE)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		4 / 5 TRP A  32
TYR A  60
HIS A 121
TRP A 122
 BCT  A1322 ( 3.3A)
BCT  A1322 ( 4.4A)
BCT  A1322 ( 3.9A)
BCT  A1322 (-4.3A)
 0.25A 2ineA-2bgsA:
42.2		 2ineA-2bgsA:
38.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ISF_A_PACA317_0
(ALDOSE REDUCTASE)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		4 / 5 TRP A  32
TYR A  60
HIS A 121
TRP A 122
 BCT  A1322 ( 3.3A)
BCT  A1322 ( 4.4A)
BCT  A1322 ( 3.9A)
BCT  A1322 (-4.3A)
 0.27A 2isfA-2bgsA:
42.0		 2isfA-2bgsA:
38.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 8 HIS A 165
HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 0.26A 2it4A-4xz5A:
28.9		 2it4A-4xz5A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		4 / 8 HIS A 167
VAL A 186
LEU A 251
THR A 252
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 0.89A 2it4A-4xz5A:
28.9		 2it4A-4xz5A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 ASN A 138
GLN A 143
HIS A 167
VAL A 186
THR A 253
 None
None
ZN  A 401 ( 3.3A)
None
BCT  A 402 ( 4.4A)
 1.21A 2pouA-4xz5A:
29.6		 2pouA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 ASN A 138
HIS A 167
VAL A 186
LEU A 251
THR A 252
THR A 253
 None
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.01A 2pouA-4xz5A:
29.6		 2pouA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 12 GLN A 163
HIS A 165
HIS A 167
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.32A 2pouA-4xz5A:
29.6		 2pouA-4xz5A:
32.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		4 / 8 GLN A 918
PHE A 914
GLY A 915
GLY A 800
 BCT  A3006 (-3.0A)
URC  A3007 ( 3.4A)
BCT  A3006 (-3.9A)
None
 0.81A 2y6rB-4yswA:
undetectable		 2y6rB-4yswA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 4mv3 BIOTIN CARBOXYLASE
(Haemophilus
influenzae) 		4 / 8 LYS A 238
ASN A 290
ARG A 292
GLU A 296
 BCT  A 503 ( 3.8A)
ACP  A 501 (-3.9A)
BCT  A 503 (-2.7A)
BCT  A 503 (-3.4A)
 0.96A 2ys6A-4mv3A:
28.4		 2ys6A-4mv3A:
26.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 2d3i OVOTRANSFERRIN
(Gallus
gallus) 		5 / 12 ILE A 127
GLY A 124
ALA A  94
VAL A 161
ASP A  60
 None
BCT  A 688 (-3.8A)
None
None
AL  A 687 ( 2.9A)
 0.93A 2yvlC-2d3iA:
undetectable		 2yvlC-2d3iA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 LEU A 260
ASP A 281
LYS A 270
ASP A 340
LEU A 368
 ZN  A 501 ( 4.8A)
ZN  A 501 (-2.4A)
ZN  A 502 (-3.6A)
ZN  A 502 (-2.9A)
BCT  A 503 (-4.5A)
 1.24A 2zj0A-4zi6A:
undetectable		 2zj0A-4zi6A:
22.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 12 ASN A 138
GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.37A 3bl1A-4xz5A:
29.3		 3bl1A-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
HIS A 184
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.50A 3bl1A-4xz5A:
29.3		 3bl1A-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 HIS A 167
VAL A 186
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.00A 3bl1A-4xz5A:
29.3		 3bl1A-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 10 HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 0.36A 3cajA-4xz5A:
29.7		 3cajA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 165
HIS A 184
THR A 252
PRO A 254
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
None
None
 1.27A 3cajA-4xz5A:
29.7		 3cajA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.01A 3cajA-4xz5A:
29.7		 3cajA-4xz5A:
32.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 5lhk LEUCINE
AMINOPEPTIDASE 2,
CHLOROPLASTIC
(Streptomyces
sp.
BC16019) 		5 / 9 PRO A 312
VAL A 349
GLY A 226
ILE A 339
GLY A 346
 None
None
None
None
BCT  A 603 (-3.3A)
 1.43A 3csjB-5lhkA:
undetectable		 3csjB-5lhkA:
19.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 12 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.53A 3czvA-4xz5A:
29.8
3czvB-4xz5A:
29.5		 3czvA-4xz5A:
30.91
3czvB-4xz5A:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 GLN A 143
HIS A 165
HIS A 167
HIS A 184
THR A 252
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
 1.05A 3czvB-4xz5A:
29.5		 3czvB-4xz5A:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.48A 3czvB-4xz5A:
29.5		 3czvB-4xz5A:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
HIS A 184
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 1.46A 3czvB-4xz5A:
29.5		 3czvB-4xz5A:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.38A 3czvB-4xz5A:
29.5		 3czvB-4xz5A:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.34A 3dazA-4xz5A:
29.8		 3dazA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.90A 3dazA-4xz5A:
29.8		 3dazA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.44A 3dazA-4xz5A:
29.8		 3dazA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 GLN A 143
HIS A 165
HIS A 167
GLU A 171
HIS A 184
THR A 252
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.00A 3dc3A-4xz5A:
29.9		 3dc3A-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 GLN A 143
HIS A 167
GLU A 171
VAL A 186
THR A 252
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.16A 3dc3A-4xz5A:
29.9		 3dc3A-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.37A 3dc3A-4xz5A:
29.9		 3dc3A-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.49A 3dc3A-4xz5A:
29.9		 3dc3A-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 GLN A 143
HIS A 165
HIS A 167
HIS A 184
THR A 252
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.01A 3dcsA-4xz5A:
29.9		 3dcsA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.42A 3dcsA-4xz5A:
29.9		 3dcsA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.92A 3dcsA-4xz5A:
29.9		 3dcsA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.41A 3dcsA-4xz5A:
29.9		 3dcsA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 10 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 0.35A 3dcwA-4xz5A:
29.9		 3dcwA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 165
HIS A 184
THR A 252
PRO A 254
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
None
None
 1.29A 3dcwA-4xz5A:
29.9		 3dcwA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 10 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 1.42A 3dcwA-4xz5A:
29.9		 3dcwA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 10 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 0.35A 3dd0A-4xz5A:
29.8		 3dd0A-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 10 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 253
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
None
None
 1.49A 3dd0A-4xz5A:
29.8		 3dd0A-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 167
HIS A 184
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.49A 3dd0A-4xz5A:
29.8		 3dd0A-4xz5A:
32.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DGQ_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR
(Homo
sapiens) 		4 / 5 ARG B  66
ILE B 416
TYR B 167
THR B 186
 TCR  B 609 ( 3.6A)
BCT  B 604 (-4.5A)
None
None
 1.49A 3dgqA-5fbhB:
undetectable		 3dgqA-5fbhB:
17.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 ASN A 138
GLN A 163
HIS A 165
HIS A 167
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 0.43A 3f4xA-4xz5A:
29.4		 3f4xA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 ASN A 138
HIS A 167
LEU A 251
THR A 252
THR A 253
PRO A 255
 None
ZN  A 401 ( 3.3A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.95A 3f4xA-4xz5A:
29.4		 3f4xA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 ASN A 138
HIS A 167
VAL A 186
LEU A 251
THR A 253
PRO A 255
 None
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
None
 0.91A 3f4xA-4xz5A:
29.4		 3f4xA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 165
VAL A 196
LEU A 251
THR A 253
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
None
None
 1.37A 3f4xA-4xz5A:
29.4		 3f4xA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.99A 3f4xA-4xz5A:
29.4		 3f4xA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 ASN A 138
HIS A 140
GLN A 163
HIS A 165
HIS A 167
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.46A 3fw3A-4xz5A:
27.5		 3fw3A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 140
GLN A 143
HIS A 165
HIS A 167
THR A 252
THR A 253
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.05A 3fw3A-4xz5A:
27.5		 3fw3A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 HIS A 140
HIS A 165
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.47A 3fw3A-4xz5A:
27.5		 3fw3A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.42A 3fw3A-4xz5A:
27.5		 3fw3A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 ASN A 138
GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.33A 3fw3B-4xz5A:
27.4		 3fw3B-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.50A 3fw3B-4xz5A:
27.4		 3fw3B-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.91A 3fw3B-4xz5A:
27.4		 3fw3B-4xz5A:
31.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 LEU A 260
ASP A 281
LYS A 270
ASP A 340
LEU A 368
 ZN  A 501 ( 4.8A)
ZN  A 501 (-2.4A)
ZN  A 502 (-3.6A)
ZN  A 502 (-2.9A)
BCT  A 503 (-4.5A)
 1.20A 3glqA-4zi6A:
undetectable		 3glqA-4zi6A:
24.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 ASN A 138
GLN A 143
HIS A 167
VAL A 186
THR A 253
 None
None
ZN  A 401 ( 3.3A)
None
BCT  A 402 ( 4.4A)
 1.20A 3hkuA-4xz5A:
29.6		 3hkuA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 12 ASN A 138
GLN A 163
HIS A 165
HIS A 167
VAL A 186
VAL A 196
LEU A 251
THR A 253
TRP A 262
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
None
 0.35A 3hkuA-4xz5A:
29.6		 3hkuA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 ASN A 138
HIS A 167
VAL A 186
LEU A 251
THR A 253
 None
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 0.92A 3hkuA-4xz5A:
29.6		 3hkuA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 GLN A 163
HIS A 165
HIS A 167
VAL A 186
LEU A 251
THR A 252
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.49A 3hkuA-4xz5A:
29.6		 3hkuA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		3 / 3 GLU A 171
HIS A 184
THR A 252
 ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
 0.17A 3hkuA-4xz5A:
29.6		 3hkuA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.27A 3hs4A-4xz5A:
29.8		 3hs4A-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
HIS A 184
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.47A 3hs4A-4xz5A:
29.8		 3hs4A-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.32A 3iaiA-4xz5A:
29.9		 3iaiA-4xz5A:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.90A 3iaiA-4xz5A:
29.9		 3iaiA-4xz5A:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.31A 3iaiB-4xz5A:
30.0		 3iaiB-4xz5A:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.89A 3iaiB-4xz5A:
30.0		 3iaiB-4xz5A:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.29A 3iaiC-4xz5A:
30.0		 3iaiC-4xz5A:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.88A 3iaiC-4xz5A:
30.0		 3iaiC-4xz5A:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.31A 3iaiD-4xz5A:
30.1		 3iaiD-4xz5A:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.87A 3iaiD-4xz5A:
30.1		 3iaiD-4xz5A:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.43A 3iaiD-4xz5A:
30.1		 3iaiD-4xz5A:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 GLN A 163
HIS A 165
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 0.40A 3kwaA-4xz5A:
29.3		 3kwaA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 165
HIS A 184
LEU A 251
THR A 252
PRO A 254
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
None
 1.38A 3kwaA-4xz5A:
29.3		 3kwaA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
 ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.13A 3kwaA-4xz5A:
29.3		 3kwaA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 GLN A 163
HIS A 165
HIS A 167
VAL A 196
LEU A 251
THR A 252
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.51A 3lxeA-4xz5A:
29.2		 3lxeA-4xz5A:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 GLN A 163
HIS A 165
HIS A 167
VAL A 196
LEU A 251
THR A 252
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.50A 3lxeB-4xz5A:
29.1		 3lxeB-4xz5A:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 0.34A 3mdzA-4xz5A:
29.3		 3mdzA-4xz5A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.95A 3mdzA-4xz5A:
29.3		 3mdzA-4xz5A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.27A 3ml5A-4xz5A:
29.9		 3ml5A-4xz5A:
32.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.95A 3ml5A-4xz5A:
29.9		 3ml5A-4xz5A:
32.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		7 / 12 SER A  79
SER A 126
ARG A 259
LYS A 216
THR A 217
GLY A 218
ASP A 222
 KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
None
 0.88A 3ny4A-4k0xA:
19.1		 3ny4A-4k0xA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 3v7p AMIDOHYDROLASE
FAMILY PROTEIN
(Nitratiruptor
sp.
SB155-2) 		5 / 12 GLY A 289
SER A 282
GLY A  76
LEU A 291
ASP A 292
 None
None
None
None
BCT  A 435 (-4.6A)
 1.46A 3r24A-3v7pA:
undetectable		 3r24A-3v7pA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R43_A_ID8A332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		5 / 12 TYR A  60
TRP A  90
HIS A 121
ASN A 167
TYR A 214
 BCT  A1322 ( 4.4A)
None
BCT  A1322 ( 3.9A)
NDP  A1321 (-3.3A)
NDP  A1321 (-3.3A)
 0.26A 3r43A-2bgsA:
39.9		 3r43A-2bgsA:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R6I_A_JMSA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		5 / 12 TYR A  60
TRP A  90
HIS A 121
ASN A 167
TYR A 214
 BCT  A1322 ( 4.4A)
None
BCT  A1322 ( 3.9A)
NDP  A1321 (-3.3A)
NDP  A1321 (-3.3A)
 0.23A 3r6iA-2bgsA:
39.8		 3r6iA-2bgsA:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RX3_A_SUZA317_1
(ALDOSE REDUCTASE)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		5 / 10 TRP A  32
TYR A  60
HIS A 121
TRP A 122
LEU A 300
 BCT  A1322 ( 3.3A)
BCT  A1322 ( 4.4A)
BCT  A1322 ( 3.9A)
BCT  A1322 (-4.3A)
None
 1.04A 3rx3A-2bgsA:
42.4		 3rx3A-2bgsA:
39.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S3G_A_TLTA317_1
(ALDOSE REDUCTASE)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		4 / 7 TRP A  32
TYR A  60
HIS A 121
TRP A 122
 BCT  A1322 ( 3.3A)
BCT  A1322 ( 4.4A)
BCT  A1322 ( 3.9A)
BCT  A1322 (-4.3A)
 0.29A 3s3gA-2bgsA:
42.4		 3s3gA-2bgsA:
39.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3h8f CYTOSOL
AMINOPEPTIDASE
(Pseudomonas
putida) 		6 / 12 LEU A 247
GLY A 266
ASP A 373
GLY A 352
ILE A 269
ILE A 226
 None
None
None
BCT  A 504 (-3.3A)
ZN  A 501 ( 4.8A)
None
 1.48A 3s54B-3h8fA:
undetectable		 3s54B-3h8fA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		7 / 12 ALA A  78
SER A  79
SER A 126
LYS A 216
THR A 217
GLY A 218
ARG A 259
 None
KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
BCT  A 301 (-3.0A)
 0.52A 3sh8A-4k0xA:
19.6		 3sh8A-4k0xA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  78
SER A  79
SER A 126
LYS A 216
GLY A 218
ARG A 259
 None
KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.4A)
BCT  A 301 (-3.0A)
 0.50A 3sh8B-4k0xA:
19.7		 3sh8B-4k0xA:
24.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		6 / 12 TYR A  60
TRP A  90
HIS A 121
ASN A 167
TYR A 214
SER A 215
 BCT  A1322 ( 4.4A)
None
BCT  A1322 ( 3.9A)
NDP  A1321 (-3.3A)
NDP  A1321 (-3.3A)
NDP  A1321 (-2.7A)
 0.36A 3ug8A-2bgsA:
39.8		 3ug8A-2bgsA:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UGR_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		5 / 12 TRP A  90
HIS A 121
TYR A 214
SER A 215
PHE A 301
 None
BCT  A1322 ( 3.9A)
NDP  A1321 (-3.3A)
NDP  A1321 (-2.7A)
None
 1.07A 3ugrA-2bgsA:
39.6		 3ugrA-2bgsA:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UGR_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		5 / 12 TRP A  90
HIS A 121
TYR A 214
SER A 215
SER A 219
 None
BCT  A1322 ( 3.9A)
NDP  A1321 (-3.3A)
NDP  A1321 (-2.7A)
NDP  A1321 (-2.7A)
 0.75A 3ugrA-2bgsA:
39.6		 3ugrA-2bgsA:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.28A 3v2jA-4xz5A:
29.9		 3v2jA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.26A 3v2mA-4xz5A:
29.7		 3v2mA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 167
HIS A 184
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.46A 3v2mA-4xz5A:
29.7		 3v2mA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.90A 3v2mA-4xz5A:
29.7		 3v2mA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.39A 3v2mA-4xz5A:
29.7		 3v2mA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		4 / 8 TRP A  32
TRP A  90
HIS A 121
TRP A 122
 BCT  A1322 ( 3.3A)
None
BCT  A1322 ( 3.9A)
BCT  A1322 (-4.3A)
 0.29A 3v35A-2bgsA:
42.7		 3v35A-2bgsA:
39.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		4 / 8 GLN A 918
PHE A 914
GLY A 915
GLY A 800
 BCT  A3006 (-3.0A)
URC  A3007 ( 3.4A)
BCT  A3006 (-3.9A)
None
 0.75A 3v3nB-4yswA:
undetectable		 3v3nB-4yswA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		4 / 8 GLN A 918
PHE A 914
GLY A 915
GLY A 800
 BCT  A3006 (-3.0A)
URC  A3007 ( 3.4A)
BCT  A3006 (-3.9A)
None
 0.74A 3v3nC-4yswA:
undetectable		 3v3nC-4yswA:
13.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 8 GLN A 163
HIS A 165
HIS A 167
HIS A 184
LEU A 251
THR A 252
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.44A 3w6hA-4xz5A:
29.2		 3w6hA-4xz5A:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 9 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
LEU A 251
THR A 252
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.43A 3w6hB-4xz5A:
29.2		 3w6hB-4xz5A:
34.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5lhk LEUCINE
AMINOPEPTIDASE 2,
CHLOROPLASTIC
(Streptomyces
sp.
BC16019) 		5 / 12 ASP A 440
ALA A 445
PHE A 390
ASP A 284
ARG A 347
 None
None
None
MN  A 601 (-2.2A)
BCT  A 603 (-3.8A)
 1.31A 3wemA-5lhkA:
undetectable		 3wemA-5lhkA:
20.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 GLN A 143
HIS A 165
HIS A 167
HIS A 184
THR A 252
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.02A 3zncA-4xz5A:
27.3		 3zncA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.46A 3zncA-4xz5A:
27.3		 3zncA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 167
HIS A 184
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.47A 3zncA-4xz5A:
27.3		 3zncA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.88A 3zncA-4xz5A:
27.3		 3zncA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.44A 3zncA-4xz5A:
27.3		 3zncA-4xz5A:
32.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 2i4c BICARBONATE
TRANSPORTER
(Synechocystis
sp.
PCC
6803) 		4 / 5 ILE A 115
GLN A  96
ILE A  66
GLU A 271
 None
None
None
BCT  A 460 ( 2.9A)
 1.15A 4a99D-2i4cA:
undetectable		 4a99D-2i4cA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		4 / 7 LEU A 251
GLU A 182
HIS A 184
HIS A 165
 BCT  A 402 (-3.8A)
None
ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.2A)
 1.24A 4aq7A-4xz5A:
undetectable		 4aq7A-4xz5A:
14.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.23A 4coqA-4xz5A:
34.7		 4coqA-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 10 GLN A 163
HIS A 165
HIS A 167
VAL A 186
VAL A 196
LEU A 251
THR A 252
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.42A 4coqA-4xz5A:
34.7		 4coqA-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 167
HIS A 184
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.49A 4coqA-4xz5A:
34.7		 4coqA-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.95A 4coqA-4xz5A:
34.7		 4coqA-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 9 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.24A 4coqB-4xz5A:
34.4		 4coqB-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 9 HIS A 167
HIS A 184
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.47A 4coqB-4xz5A:
34.4		 4coqB-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.97A 4coqB-4xz5A:
34.4		 4coqB-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.42A 4coqB-4xz5A:
34.4		 4coqB-4xz5A:
42.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 4mv3 BIOTIN CARBOXYLASE
(Haemophilus
influenzae) 		5 / 12 ARG A 338
GLU A 241
LEU A 308
GLU A 211
ASN A 290
 BCT  A 503 (-3.5A)
None
None
None
ACP  A 501 (-3.9A)
 1.47A 4cpzB-4mv3A:
undetectable		 4cpzB-4mv3A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 4mv3 BIOTIN CARBOXYLASE
(Haemophilus
influenzae) 		5 / 12 ARG A 338
GLU A 241
LEU A 308
ALA A 272
GLU A 211
 BCT  A 503 (-3.5A)
None
None
None
None
 1.30A 4cpzD-4mv3A:
undetectable		 4cpzD-4mv3A:
20.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 10 GLN A 163
VAL A 186
LEU A 194
VAL A 196
LEU A 251
THR A 252
THR A 253
VAL A 260
TRP A 262
 None
None
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 0.42A 4e3hA-4xz5A:
29.7		 4e3hA-4xz5A:
32.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		5 / 10 SER A 126
LYS A 216
THR A 217
GLY A 218
ARG A 259
 BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
BCT  A 301 (-3.0A)
 0.85A 4fh2A-4k0xA:
18.3		 4fh2A-4k0xA:
24.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 GLN A 163
HIS A 165
GLU A 182
VAL A 186
THR A 252
 None
ZN  A 401 ( 3.2A)
None
None
BCT  A 402 (-3.7A)
 1.26A 4g0cA-4xz5A:
29.8		 4g0cA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.29A 4g0cA-4xz5A:
29.8		 4g0cA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.88A 4g0cA-4xz5A:
29.8		 4g0cA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
LEU A 251
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.24A 4g7aA-4xz5A:
32.8		 4g7aA-4xz5A:
38.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.27A 4g7aA-4xz5A:
32.8		 4g7aA-4xz5A:
38.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.48A 4g7aA-4xz5A:
32.8		 4g7aA-4xz5A:
38.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.90A 4g7aA-4xz5A:
32.8		 4g7aA-4xz5A:
38.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
LEU A 251
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.27A 4g7aB-4xz5A:
32.7		 4g7aB-4xz5A:
38.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.29A 4g7aB-4xz5A:
32.7		 4g7aB-4xz5A:
38.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.50A 4g7aB-4xz5A:
32.7		 4g7aB-4xz5A:
38.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 167
GLU A 171
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.04A 4g7aB-4xz5A:
32.7		 4g7aB-4xz5A:
38.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JQ4_B_IMNB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		5 / 10 TYR A  60
HIS A 121
ASN A 167
TYR A 214
LEU A 295
 BCT  A1322 ( 4.4A)
BCT  A1322 ( 3.9A)
NDP  A1321 (-3.3A)
NDP  A1321 (-3.3A)
NDP  A1321 (-4.8A)
 0.68A 4jq4B-2bgsA:
39.8		 4jq4B-2bgsA:
32.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		4 / 8 TYR A  60
TRP A  90
HIS A 121
LEU A 295
 BCT  A1322 ( 4.4A)
None
BCT  A1322 ( 3.9A)
NDP  A1321 (-4.8A)
 0.70A 4jtrA-2bgsA:
40.0		 4jtrA-2bgsA:
32.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.30A 4k0sA-4xz5A:
29.8		 4k0sA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
HIS A 184
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.49A 4k0sA-4xz5A:
29.8		 4k0sA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 0.39A 4k0zA-4xz5A:
29.6		 4k0zA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 HIS A 165
HIS A 184
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 1.50A 4k0zA-4xz5A:
29.6		 4k0zA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.06A 4k0zA-4xz5A:
29.6		 4k0zA-4xz5A:
32.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 194
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.30A 4k13A-4xz5A:
29.8		 4k13A-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 GLN A 163
HIS A 165
HIS A 167
VAL A 186
LEU A 194
LEU A 251
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.43A 4k13A-4xz5A:
29.8		 4k13A-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
HIS A 184
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.46A 4k13A-4xz5A:
29.8		 4k13A-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
VAL A 196
LEU A 194
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.32A 4k13A-4xz5A:
29.8		 4k13A-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 184
HIS A 172
VAL A 196
LEU A 194
LEU A 251
THR A 252
 ZN  A 401 ( 3.1A)
None
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.47A 4k13A-4xz5A:
29.8		 4k13A-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 4q2h PROLINE RACEMASE
PROTEIN
(Agrobacterium
tumefaciens) 		8 / 9 SER A  93
GLY A  94
SER A  95
TYR A 177
ASP A 251
SER A 253
GLY A 256
THR A 257
 BCT  A 401 (-3.5A)
BCT  A 401 (-3.6A)
BCT  A 401 (-3.4A)
CSO  A 255 ( 4.8A)
CSO  A 255 (-3.5A)
CSO  A 255 ( 3.0A)
CSO  A 255 (-2.4A)
BCT  A 401 (-2.8A)
 0.11A 4lb0A-4q2hA:
59.7		 4lb0A-4q2hA:
77.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 4q2h PROLINE RACEMASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 9 SER A  93
GLY A  94
SER A  95
TYR A 227
SER A 253
 BCT  A 401 (-3.5A)
BCT  A 401 (-3.6A)
BCT  A 401 (-3.4A)
None
CSO  A 255 ( 3.0A)
 0.97A 4lb0A-4q2hA:
59.7		 4lb0A-4q2hA:
77.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 2ist RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE D
(Escherichia
coli) 		4 / 7 PRO A 302
VAL A 306
MET A 305
PHE A 274
 None
BCT  A 803 ( 4.1A)
None
None
 1.07A 4lb2A-2istA:
undetectable		 4lb2A-2istA:
18.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 GLN A 143
HIS A 167
GLU A 171
LEU A 251
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.13A 4lu3A-4xz5A:
29.4		 4lu3A-4xz5A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.30A 4lu3A-4xz5A:
29.4		 4lu3A-4xz5A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.83A 4lu3A-4xz5A:
29.4		 4lu3A-4xz5A:
30.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 ASN A 138
GLN A 163
HIS A 165
HIS A 167
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 0.38A 4m2rA-4xz5A:
29.9		 4m2rA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 165
VAL A 196
LEU A 251
THR A 253
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
None
None
 1.30A 4m2rA-4xz5A:
29.9		 4m2rA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 TRP A  78
HIS A 140
GLN A 163
HIS A 165
HIS A 167
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.31A 4m2uA-4xz5A:
29.9		 4m2uA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 TRP A  78
HIS A 140
HIS A 165
VAL A 196
LEU A 251
THR A 253
TRP A 262
 None
None
ZN  A 401 ( 3.2A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
None
 1.41A 4m2uA-4xz5A:
29.9		 4m2uA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 TRP A  78
HIS A 140
HIS A 167
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
None
ZN  A 401 ( 3.3A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.33A 4m2uA-4xz5A:
29.9		 4m2uA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 12 TRP A  89
HIS A 165
HIS A 167
VAL A 186
VAL A 196
LEU A 251
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
None
 1.41A 4m2uA-4xz5A:
29.9		 4m2uA-4xz5A:
33.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 165
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.40A 4m2vA-4xz5A:
29.9		 4m2vA-4xz5A:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
VAL A 196
GLY A 192
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.00A 4m2vA-4xz5A:
29.9		 4m2vA-4xz5A:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 12 LEU A 162
GLN A 163
HIS A 165
HIS A 167
VAL A 186
GLY A 192
LEU A 251
THR A 252
THR A 253
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.24A 4m2vA-4xz5A:
29.9		 4m2vA-4xz5A:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 12 LEU A 162
GLN A 163
HIS A 165
HIS A 167
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.60A 4m2vA-4xz5A:
29.9		 4m2vA-4xz5A:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
HIS A 184
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.46A 4m2wA-4xz5A:
29.9		 4m2wA-4xz5A:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		12 / 12 LEU A 162
GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 194
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.59A 4m2wA-4xz5A:
29.9		 4m2wA-4xz5A:
33.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 12 LEU A 162
GLN A 163
HIS A 165
HIS A 167
VAL A 186
LEU A 194
LEU A 251
THR A 253
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.47A 4m2wA-4xz5A:
29.9		 4m2wA-4xz5A:
33.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 1vrg PROPIONYL-COA
CARBOXYLASE, BETA
SUBUNIT
(Thermotoga
maritima) 		5 / 11 VAL A 174
ALA A 173
TYR A 175
GLY A 196
GLY A 132
 None
None
None
BCT  A 517 (-3.7A)
None
 1.20A 4mm9A-1vrgA:
0.0		 4mm9A-1vrgA:
23.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 4mv3 BIOTIN CARBOXYLASE
(Haemophilus
influenzae) 		6 / 7 LYS A 238
ASN A 290
ARG A 292
VAL A 295
GLU A 296
ARG A 338
 BCT  A 503 ( 3.8A)
ACP  A 501 (-3.9A)
BCT  A 503 (-2.7A)
BCT  A 503 (-3.8A)
BCT  A 503 (-3.4A)
BCT  A 503 (-3.5A)
 0.35A 4mv7A-4mv3A:
65.5		 4mv7A-4mv3A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 4mv3 BIOTIN CARBOXYLASE
(Haemophilus
influenzae) 		6 / 7 LYS A 238
ASN A 290
GLN A 294
VAL A 295
GLU A 296
ARG A 338
 BCT  A 503 ( 3.8A)
ACP  A 501 (-3.9A)
BCT  A 503 (-4.3A)
BCT  A 503 (-3.8A)
BCT  A 503 (-3.4A)
BCT  A 503 (-3.5A)
 0.69A 4mv7A-4mv3A:
65.5		 4mv7A-4mv3A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 8 GLN A 163
HIS A 165
HIS A 167
HIS A 184
THR A 252
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.32A 4n16A-4xz5A:
30.0		 4n16A-4xz5A:
32.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		7 / 12 ALA A  78
SER A  79
SER A 126
LYS A 216
THR A 217
GLY A 218
ARG A 259
 None
KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
BCT  A 301 (-3.0A)
 0.55A 4n9kA-4k0xA:
19.5		 4n9kA-4k0xA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		7 / 12 ALA A  78
SER A  79
SER A 126
LYS A 216
THR A 217
GLY A 218
ARG A 259
 None
KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
BCT  A 301 (-3.0A)
 0.53A 4n9kB-4k0xA:
19.3		 4n9kB-4k0xA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_ACTA605_0
(SERUM ALBUMIN)		 5nth PUTATIVE
AMINOPEPTIDASE
(Leishmania
major) 		3 / 3 LYS A 311
LYS A 299
ALA A 390
 BB2  A 604 ( 2.6A)
MN  A 602 ( 2.0A)
BCT  A 601 (-3.6A)
 1.14A 4ot2A-5nthA:
1.0		 4ot2A-5nthA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 2ist RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE D
(Escherichia
coli) 		4 / 8 TYR A 122
ILE A  86
ILE A  94
LYS A 150
 BCT  A 804 ( 4.3A)
None
None
None
 0.98A 4ou1A-2istA:
undetectable		 4ou1A-2istA:
22.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 9 GLN A 163
HIS A 165
HIS A 167
HIS A 184
THR A 252
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.26A 4pxxA-4xz5A:
29.8		 4pxxA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
VAL A 186
VAL A 196
THR A 252
TRP A 262
 ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.7A)
None
 0.21A 4twlA-4xz5A:
30.0		 4twlA-4xz5A:
35.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
VAL A 186
VAL A 196
THR A 252
TRP A 262
 ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.7A)
None
 0.22A 4twlB-4xz5A:
30.2		 4twlB-4xz5A:
35.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 ( 4.4A)
 1.12A 4uovA-4xz5A:
34.3		 4uovA-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.31A 4uovA-4xz5A:
34.3		 4uovA-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.49A 4uovA-4xz5A:
34.3		 4uovA-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.98A 4uovA-4xz5A:
34.3		 4uovA-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 ( 4.4A)
 1.11A 4uovB-4xz5A:
34.4		 4uovB-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.26A 4uovB-4xz5A:
34.4		 4uovB-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.50A 4uovB-4xz5A:
34.4		 4uovB-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.94A 4uovB-4xz5A:
34.4		 4uovB-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 ( 4.4A)
 1.12A 4uovC-4xz5A:
34.3		 4uovC-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.30A 4uovC-4xz5A:
34.3		 4uovC-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.97A 4uovC-4xz5A:
34.3		 4uovC-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 ( 4.4A)
 1.11A 4uovD-4xz5A:
34.4		 4uovD-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.29A 4uovD-4xz5A:
34.4		 4uovD-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.49A 4uovD-4xz5A:
34.4		 4uovD-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.96A 4uovD-4xz5A:
34.4		 4uovD-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 ( 4.4A)
 1.12A 4uovE-4xz5A:
34.3		 4uovE-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.29A 4uovE-4xz5A:
34.3		 4uovE-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.95A 4uovE-4xz5A:
34.3		 4uovE-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.46A 4uovE-4xz5A:
34.3		 4uovE-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 ( 4.4A)
 1.10A 4uovF-4xz5A:
34.4		 4uovF-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.29A 4uovF-4xz5A:
34.4		 4uovF-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.49A 4uovF-4xz5A:
34.4		 4uovF-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.95A 4uovF-4xz5A:
34.4		 4uovF-4xz5A:
42.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
LEU A 251
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.29A 4x5sA-4xz5A:
32.7		 4x5sA-4xz5A:
42.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.32A 4x5sA-4xz5A:
32.7		 4x5sA-4xz5A:
42.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.91A 4x5sA-4xz5A:
32.7		 4x5sA-4xz5A:
42.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.41A 4x5sA-4xz5A:
32.7		 4x5sA-4xz5A:
42.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
LEU A 251
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.29A 4x5sB-4xz5A:
32.8		 4x5sB-4xz5A:
42.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.31A 4x5sB-4xz5A:
32.8		 4x5sB-4xz5A:
42.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.92A 4x5sB-4xz5A:
32.8		 4x5sB-4xz5A:
42.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.41A 4x5sB-4xz5A:
32.8		 4x5sB-4xz5A:
42.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.34A 4xiwA-4xz5A:
28.4
4xiwH-4xz5A:
28.6		 4xiwA-4xz5A:
40.80
4xiwH-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 HIS A 167
GLU A 171
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.95A 4xiwA-4xz5A:
28.4
4xiwH-4xz5A:
28.6		 4xiwA-4xz5A:
40.80
4xiwH-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.45A 4xiwA-4xz5A:
28.4
4xiwH-4xz5A:
28.6		 4xiwA-4xz5A:
40.80
4xiwH-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 12 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.33A 4xiwB-4xz5A:
28.5
4xiwE-4xz5A:
28.5		 4xiwB-4xz5A:
40.80
4xiwE-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.88A 4xiwB-4xz5A:
28.5
4xiwE-4xz5A:
28.5		 4xiwB-4xz5A:
40.80
4xiwE-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.42A 4xiwB-4xz5A:
28.5
4xiwE-4xz5A:
28.5		 4xiwB-4xz5A:
40.80
4xiwE-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.40A 4xiwC-4xz5A:
28.2		 4xiwC-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 167
GLU A 171
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.94A 4xiwC-4xz5A:
28.2		 4xiwC-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.32A 4xiwD-4xz5A:
28.8		 4xiwD-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 167
GLU A 171
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.99A 4xiwD-4xz5A:
28.8		 4xiwD-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.33A 4xiwE-4xz5A:
28.5		 4xiwE-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 167
GLU A 171
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.00A 4xiwE-4xz5A:
28.5		 4xiwE-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.45A 4xiwE-4xz5A:
28.5		 4xiwE-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.29A 4xiwF-4xz5A:
28.5		 4xiwF-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 11 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.46A 4xiwF-4xz5A:
28.5		 4xiwF-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.89A 4xiwF-4xz5A:
28.5		 4xiwF-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		12 / 12 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 194
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.42A 4xiwG-4xz5A:
28.6		 4xiwG-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 12 HIS A 167
GLU A 171
HIS A 184
VAL A 196
LEU A 194
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.15A 4xiwG-4xz5A:
28.6		 4xiwG-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.36A 4xiwH-4xz5A:
28.6		 4xiwH-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.86A 4xiwH-4xz5A:
28.6		 4xiwH-4xz5A:
40.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 11 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.36A 4ygfA-4xz5A:
29.6		 4ygfA-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 11 HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.28A 4ygfB-4xz5A:
29.8		 4ygfB-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 1.45A 4ygfB-4xz5A:
29.8		 4ygfB-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 HIS A 167
HIS A 165
VAL A 186
LEU A 251
THR A 252
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.2A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.45A 4ygfB-4xz5A:
29.8		 4ygfB-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 11 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.29A 4ygfC-4xz5A:
21.5		 4ygfC-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 11 HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.28A 4ygfD-4xz5A:
4.6		 4ygfD-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 251
THR A 252
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.08A 4ygfD-4xz5A:
4.6		 4ygfD-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.37A 4ygfD-4xz5A:
4.6		 4ygfD-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 12 HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.30A 4ygfE-4xz5A:
29.8		 4ygfE-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 9 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.29A 4ygfF-4xz5A:
29.4		 4ygfF-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 167
HIS A 184
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 1.50A 4ygfF-4xz5A:
29.4		 4ygfF-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.43A 4ygfF-4xz5A:
29.4		 4ygfF-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 12 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.28A 4ygfG-4xz5A:
6.8		 4ygfG-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 9 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.31A 4ygfH-4xz5A:
29.6		 4ygfH-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 167
HIS A 165
VAL A 186
LEU A 251
THR A 252
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.2A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.41A 4ygfH-4xz5A:
29.6		 4ygfH-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 12 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.47A 4yhaA-4xz5A:
29.5		 4yhaA-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.09A 4yhaA-4xz5A:
29.5		 4yhaA-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 10 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 0.51A 4yhaB-4xz5A:
28.7		 4yhaB-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 11 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.38A 4yhaC-4xz5A:
29.8		 4yhaC-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.18A 4yhaC-4xz5A:
29.8		 4yhaC-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 11 HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.34A 4yhaD-4xz5A:
28.4		 4yhaD-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
HIS A 184
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.10A 4yhaD-4xz5A:
28.4		 4yhaD-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 12 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
None
 0.43A 4yhaE-4xz5A:
29.9		 4yhaE-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 165
HIS A 184
LEU A 251
THR A 252
PRO A 254
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
None
 1.42A 4yhaE-4xz5A:
29.9		 4yhaE-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
None
 1.48A 4yhaE-4xz5A:
29.9		 4yhaE-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
PRO A 255
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 1.16A 4yhaE-4xz5A:
29.9		 4yhaE-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 10 HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.61A 4yhaF-4xz5A:
27.0		 4yhaF-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 12 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.37A 4yhaG-4xz5A:
29.1		 4yhaG-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 HIS A 167
HIS A 184
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 1.49A 4yhaG-4xz5A:
29.1		 4yhaG-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.13A 4yhaG-4xz5A:
29.1		 4yhaG-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 10 HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.33A 4yhaH-4xz5A:
29.4		 4yhaH-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.03A 4yhaH-4xz5A:
29.4		 4yhaH-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		5 / 12 TYR A  60
TRP A  90
HIS A 121
ASN A 167
LEU A 295
 BCT  A1322 ( 4.4A)
None
BCT  A1322 ( 3.9A)
NDP  A1321 (-3.3A)
NDP  A1321 (-4.8A)
 0.55A 4yvpB-2bgsA:
40.2		 4yvpB-2bgsA:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVV_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		5 / 9 TYR A  60
TRP A  90
HIS A 121
ASN A 167
TYR A 214
 BCT  A1322 ( 4.4A)
None
BCT  A1322 ( 3.9A)
NDP  A1321 (-3.3A)
NDP  A1321 (-3.3A)
 0.21A 4yvvA-2bgsA:
39.7		 4yvvA-2bgsA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVX_A_GMRA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		5 / 12 TYR A  60
TRP A  90
HIS A 121
LEU A 126
ASN A 167
 BCT  A1322 ( 4.4A)
None
BCT  A1322 ( 3.9A)
None
NDP  A1321 (-3.3A)
 0.22A 4yvxA-2bgsA:
39.5		 4yvxA-2bgsA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVX_B_GMRB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		5 / 12 TYR A  60
TRP A  90
HIS A 121
LEU A 126
ASN A 167
 BCT  A1322 ( 4.4A)
None
BCT  A1322 ( 3.9A)
None
NDP  A1321 (-3.3A)
 0.19A 4yvxB-2bgsA:
39.3		 4yvxB-2bgsA:
34.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 GLN A 143
HIS A 167
GLU A 171
VAL A 186
THR A 252
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.19A 5c8iA-4xz5A:
29.8		 5c8iA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 GLN A 163
HIS A 165
HIS A 167
GLU A 171
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 0.41A 5c8iA-4xz5A:
29.8		 5c8iA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 165
VAL A 196
LEU A 251
THR A 253
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
None
None
 1.27A 5c8iA-4xz5A:
29.8		 5c8iA-4xz5A:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 5d4o NITROGEN REGULATORY
PROTEIN P-II
(Thiomonas
intermedia) 		4 / 5 VAL A 100
GLY A 101
ARG A 102
PHE A 106
 BCT  A 202 (-3.5A)
BCT  A 202 (-3.5A)
BCT  A 202 (-3.7A)
AMP  A 203 (-4.3A)
 0.35A 5d4nA-5d4oA:
21.2
5d4nC-5d4oA:
17.4		 5d4nA-5d4oA:
100.00
5d4nC-5d4oA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  78
SER A  79
SER A 126
LYS A 216
GLY A 218
ARG A 259
 None
KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.4A)
BCT  A 301 (-3.0A)
 0.53A 5ghyA-4k0xA:
19.6		 5ghyA-4k0xA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  78
SER A  79
SER A 126
LYS A 216
GLY A 218
ARG A 259
 None
KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.4A)
BCT  A 301 (-3.0A)
 0.52A 5ghyB-4k0xA:
19.4		 5ghyB-4k0xA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		7 / 11 ALA A  78
SER A  79
SER A 126
LYS A 216
THR A 217
GLY A 218
ARG A 259
 None
KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
BCT  A 301 (-3.0A)
 0.52A 5ghzA-4k0xA:
19.4		 5ghzA-4k0xA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		7 / 10 ALA A  78
SER A  79
SER A 126
LYS A 216
THR A 217
GLY A 218
ARG A 259
 None
KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
BCT  A 301 (-3.0A)
 0.54A 5ghzB-4k0xA:
19.3		 5ghzB-4k0xA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 5lhk LEUCINE
AMINOPEPTIDASE 2,
CHLOROPLASTIC
(Streptomyces
sp.
BC16019) 		4 / 8 ASN A 344
GLU A 420
HIS A 438
THR A 373
 BCT  A 603 (-4.0A)
None
None
None
 1.29A 5hqaA-5lhkA:
undetectable		 5hqaA-5lhkA:
22.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.38A 5jn8A-4xz5A:
27.3		 5jn8A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 165
HIS A 167
VAL A 186
LEU A 251
THR A 253
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.16A 5jn8A-4xz5A:
27.3		 5jn8A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 10 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.50A 5jn8A-4xz5A:
27.3		 5jn8A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.04A 5jn8A-4xz5A:
27.3		 5jn8A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 ( 4.4A)
 1.16A 5jn8B-4xz5A:
27.5		 5jn8B-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.39A 5jn8B-4xz5A:
27.5		 5jn8B-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.98A 5jn8B-4xz5A:
27.5		 5jn8B-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 9 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.36A 5jn8C-4xz5A:
27.1		 5jn8C-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 9 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.17A 5jn8C-4xz5A:
27.1		 5jn8C-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 10 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.31A 5jn8D-4xz5A:
26.8		 5jn8D-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.96A 5jn8D-4xz5A:
26.8		 5jn8D-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.47A 5jn8D-4xz5A:
26.8		 5jn8D-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.39A 5jn9A-4xz5A:
27.3		 5jn9A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
HIS A 165
THR A 253
THR A 252
TRP A  78
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.2A)
BCT  A 402 ( 4.4A)
BCT  A 402 (-3.7A)
None
 1.36A 5jn9A-4xz5A:
27.3		 5jn9A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.05A 5jn9A-4xz5A:
27.3		 5jn9A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.38A 5jn9B-4xz5A:
27.6		 5jn9B-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
HIS A 165
THR A 253
THR A 252
TRP A  78
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.2A)
BCT  A 402 ( 4.4A)
BCT  A 402 (-3.7A)
None
 1.35A 5jn9B-4xz5A:
27.6		 5jn9B-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.94A 5jn9B-4xz5A:
27.6		 5jn9B-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 9 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.33A 5jn9C-4xz5A:
27.1		 5jn9C-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 9 GLN A 163
HIS A 165
HIS A 167
VAL A 186
LEU A 251
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.43A 5jn9C-4xz5A:
27.1		 5jn9C-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 167
HIS A 165
THR A 253
THR A 252
TRP A  78
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.2A)
BCT  A 402 ( 4.4A)
BCT  A 402 (-3.7A)
None
 1.34A 5jn9C-4xz5A:
27.1		 5jn9C-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 9 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.13A 5jn9C-4xz5A:
27.1		 5jn9C-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.45A 5jn9C-4xz5A:
27.1		 5jn9C-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.34A 5jn9D-4xz5A:
26.8		 5jn9D-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
HIS A 165
THR A 253
THR A 252
TRP A  78
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.2A)
BCT  A 402 ( 4.4A)
BCT  A 402 (-3.7A)
None
 1.31A 5jn9D-4xz5A:
26.8		 5jn9D-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.13A 5jn9D-4xz5A:
26.8		 5jn9D-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 ASN A 138
GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.48A 5jnaA-4xz5A:
27.3		 5jnaA-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 GLN A 143
HIS A 165
HIS A 167
GLU A 171
VAL A 186
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 ( 4.4A)
 1.26A 5jnaA-4xz5A:
27.3		 5jnaA-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 GLN A 163
HIS A 165
HIS A 167
VAL A 186
LEU A 251
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.46A 5jnaA-4xz5A:
27.3		 5jnaA-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 165
HIS A 167
GLU A 171
VAL A 186
LEU A 251
THR A 253
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.27A 5jnaA-4xz5A:
27.3		 5jnaA-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 167
GLU A 171
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.97A 5jnaA-4xz5A:
27.3		 5jnaA-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 ASN A 138
GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.46A 5jnaB-4xz5A:
27.6		 5jnaB-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 GLN A 143
HIS A 165
HIS A 167
HIS A 184
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 ( 4.4A)
 1.08A 5jnaB-4xz5A:
27.6		 5jnaB-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.47A 5jnaB-4xz5A:
27.6		 5jnaB-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 11 ASN A 138
GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.48A 5jnaC-4xz5A:
27.0		 5jnaC-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 GLN A 143
HIS A 165
HIS A 167
VAL A 186
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 ( 4.4A)
 1.07A 5jnaC-4xz5A:
27.0		 5jnaC-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 11 GLN A 163
HIS A 165
HIS A 167
VAL A 186
LEU A 251
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.43A 5jnaC-4xz5A:
27.0		 5jnaC-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 HIS A 165
HIS A 167
VAL A 186
LEU A 251
THR A 253
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.16A 5jnaC-4xz5A:
27.0		 5jnaC-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.04A 5jnaC-4xz5A:
27.0		 5jnaC-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 ASN A 138
GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.43A 5jnaD-4xz5A:
26.8		 5jnaD-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 GLN A 143
HIS A 165
HIS A 167
VAL A 186
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 ( 4.4A)
 1.08A 5jnaD-4xz5A:
26.8		 5jnaD-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 165
HIS A 167
VAL A 186
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.10A 5jnaD-4xz5A:
26.8		 5jnaD-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.49A 5jnaD-4xz5A:
26.8		 5jnaD-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 GLN A 143
HIS A 167
GLU A 171
VAL A 186
THR A 253
 None
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
None
BCT  A 402 ( 4.4A)
 1.19A 5jncA-4xz5A:
27.3		 5jncA-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 11 GLN A 163
HIS A 165
GLU A 182
VAL A 186
THR A 252
 None
ZN  A 401 ( 3.2A)
None
None
BCT  A 402 (-3.7A)
 1.30A 5jncA-4xz5A:
27.3		 5jncA-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 11 GLN A 163
HIS A 165
HIS A 167
GLU A 171
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 4.5A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.41A 5jncA-4xz5A:
27.3		 5jncA-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.32A 5jncB-4xz5A:
27.6		 5jncB-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.11A 5jncB-4xz5A:
27.6		 5jncB-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.42A 5jncB-4xz5A:
27.6		 5jncB-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 9 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.32A 5jncC-4xz5A:
27.0		 5jncC-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.00A 5jncC-4xz5A:
27.0		 5jncC-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 9 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.28A 5jncD-4xz5A:
26.8		 5jncD-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 9 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.13A 5jncD-4xz5A:
26.8		 5jncD-4xz5A:
31.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 4q2h PROLINE RACEMASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 THR A 257
GLY A 173
VAL A 147
ALA A  91
ILE A 222
 BCT  A 401 (-2.8A)
None
None
None
None
 0.88A 5kb6A-4q2hA:
undetectable		 5kb6A-4q2hA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 4q2h PROLINE RACEMASE
PROTEIN
(Agrobacterium
tumefaciens) 		5 / 12 THR A 257
GLY A 173
VAL A 147
ALA A  91
ILE A 222
 BCT  A 401 (-2.8A)
None
None
None
None
 0.88A 5kb6B-4q2hA:
undetectable		 5kb6B-4q2hA:
23.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.39A 5ku6A-4xz5A:
27.3		 5ku6A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
HIS A 165
THR A 253
THR A 252
TRP A  78
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.2A)
BCT  A 402 ( 4.4A)
BCT  A 402 (-3.7A)
None
 1.35A 5ku6A-4xz5A:
27.3		 5ku6A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.04A 5ku6A-4xz5A:
27.3		 5ku6A-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 10 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.35A 5ku6B-4xz5A:
27.6		 5ku6B-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.12A 5ku6B-4xz5A:
27.6		 5ku6B-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.46A 5ku6B-4xz5A:
27.6		 5ku6B-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 9 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.35A 5ku6C-4xz5A:
27.1		 5ku6C-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.05A 5ku6C-4xz5A:
27.1		 5ku6C-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 9 GLN A 163
HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.33A 5ku6D-4xz5A:
26.9		 5ku6D-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.02A 5ku6D-4xz5A:
26.9		 5ku6D-4xz5A:
31.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 184
HIS A 167
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.1A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.47A 5ku6D-4xz5A:
26.9		 5ku6D-4xz5A:
31.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 7 GLN A 163
HIS A 165
VAL A 186
LEU A 251
THR A 252
THR A 253
 None
ZN  A 401 ( 3.2A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.32A 5m78A-4xz5A:
29.7		 5m78A-4xz5A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 7 GLN A 163
HIS A 165
VAL A 186
LEU A 251
THR A 253
 None
ZN  A 401 ( 3.2A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.38A 5m78A-4xz5A:
29.7		 5m78A-4xz5A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		4 / 7 VAL A 196
LEU A 251
THR A 252
THR A 253
 None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 0.93A 5m78A-4xz5A:
29.7		 5m78A-4xz5A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 2i4c BICARBONATE
TRANSPORTER
(Synechocystis
sp.
PCC
6803) 		4 / 7 PRO A 224
ILE A  68
ILE A  66
THR A 192
 None
BCT  A 460 (-4.5A)
None
BCT  A 460 (-2.7A)
 0.91A 5murB-2i4cA:
undetectable		 5murB-2i4cA:
13.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		4 / 6 HIS A 165
HIS A 167
LEU A 251
THR A 253
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.26A 5ogjA-4xz5A:
29.6		 5ogjA-4xz5A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 6 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.28A 5ogjA-4xz5A:
29.6		 5ogjA-4xz5A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 6 HIS A 167
HIS A 184
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 1.50A 5ogjA-4xz5A:
29.6		 5ogjA-4xz5A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		4 / 6 HIS A 165
HIS A 167
LEU A 251
THR A 253
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.26A 5ogjB-4xz5A:
29.2		 5ogjB-4xz5A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 6 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.26A 5ogjB-4xz5A:
29.2		 5ogjB-4xz5A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 6 HIS A 167
HIS A 184
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 1.50A 5ogjB-4xz5A:
29.2		 5ogjB-4xz5A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		4 / 5 HIS A 165
HIS A 167
LEU A 251
THR A 253
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.27A 5ohhA-4xz5A:
29.2		 5ohhA-4xz5A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 5 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 0.19A 5ohhA-4xz5A:
29.2		 5ohhA-4xz5A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		4 / 6 HIS A 165
HIS A 167
LEU A 251
THR A 253
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
 1.26A 5ohhB-4xz5A:
29.5		 5ohhB-4xz5A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 6 HIS A 165
HIS A 184
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.27A 5ohhB-4xz5A:
29.5		 5ohhB-4xz5A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 6 HIS A 167
HIS A 184
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 1.49A 5ohhB-4xz5A:
29.5		 5ohhB-4xz5A:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 10 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
None
 0.45A 5tt3A-4xz5A:
29.6		 5tt3A-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 165
HIS A 167
VAL A 186
LEU A 251
PRO A 255
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
None
 1.07A 5tt3A-4xz5A:
29.6		 5tt3A-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 165
HIS A 184
THR A 252
PRO A 254
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.7A)
None
None
 1.31A 5tt3A-4xz5A:
29.6		 5tt3A-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 165
HIS A 184
VAL A 196
LEU A 251
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
None
None
 1.48A 5tt3A-4xz5A:
29.6		 5tt3A-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 10 HIS A 167
VAL A 196
LEU A 251
THR A 252
PRO A 255
 ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 1.22A 5tt3A-4xz5A:
29.6		 5tt3A-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 9 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.39A 5tt3B-4xz5A:
27.6		 5tt3B-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		9 / 10 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
None
 0.34A 5tt3C-4xz5A:
29.9		 5tt3C-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 165
HIS A 184
LEU A 251
THR A 252
PRO A 254
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
None
 1.47A 5tt3C-4xz5A:
29.9		 5tt3C-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 165
HIS A 184
VAL A 196
LEU A 251
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
None
None
 1.39A 5tt3C-4xz5A:
29.9		 5tt3C-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 10 HIS A 167
HIS A 165
VAL A 186
LEU A 251
THR A 252
PRO A 255
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.2A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 1.45A 5tt3C-4xz5A:
29.9		 5tt3C-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 9 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.32A 5tt3E-4xz5A:
29.8		 5tt3E-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.01A 5tt3E-4xz5A:
29.8		 5tt3E-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 8 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.44A 5tt3F-4xz5A:
28.9		 5tt3F-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 8 HIS A 165
HIS A 184
VAL A 196
LEU A 251
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
None
 1.42A 5tt3F-4xz5A:
28.9		 5tt3F-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		8 / 9 HIS A 165
HIS A 167
HIS A 184
VAL A 186
VAL A 196
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.34A 5tt3G-4xz5A:
28.7		 5tt3G-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 9 HIS A 167
HIS A 184
VAL A 196
LEU A 251
THR A 252
 ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
 1.02A 5tt3G-4xz5A:
28.7		 5tt3G-4xz5A:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 8 HIS A 165
HIS A 167
HIS A 184
VAL A 186
LEU A 251
THR A 252
TRP A 262
 ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
ZN  A 401 ( 3.1A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
None
 0.40A 5tt3H-4xz5A:
29.0		 5tt3H-4xz5A:
35.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E
(Rattus
norvegicus) 		3 / 3 GLU A 740
HIS A 741
ARG A 839
 None
None
BCT  A3006 (-4.0A)
 0.93A 5uunA-4yswA:
undetectable		 5uunA-4yswA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		7 / 12 SER A  79
SER A 126
ARG A 259
LYS A 216
THR A 217
GLY A 218
ASP A 222
 KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
None
 0.88A 6b5yB-4k0xA:
19.1		 6b5yB-4k0xA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  79
SER A 126
LYS A 216
THR A 217
GLY A 218
ASP A 222
 KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
None
 0.75A 6b5yD-4k0xA:
19.2		 6b5yD-4k0xA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  79
SER A 126
LYS A 216
THR A 217
GLY A 218
ASP A 222
 KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
None
 0.64A 6b68B-4k0xA:
19.3		 6b68B-4k0xA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  79
SER A 126
ARG A 259
LYS A 216
GLY A 218
ASP A 222
 KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.4A)
None
 0.89A 6b68D-4k0xA:
19.3		 6b68D-4k0xA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  79
SER A 126
LYS A 216
THR A 217
GLY A 218
ASP A 222
 KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
None
 0.59A 6b69A-4k0xA:
19.2
6b69B-4k0xA:
19.2		 6b69A-4k0xA:
16.15
6b69B-4k0xA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  79
SER A 126
ARG A 259
LYS A 216
THR A 217
GLY A 218
 KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
 0.75A 6b69D-4k0xA:
19.2		 6b69D-4k0xA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		7 / 12 SER A  79
SER A 126
ARG A 259
LYS A 216
THR A 217
GLY A 218
ASP A 222
 KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
None
 0.82A 6b6aB-4k0xA:
19.1		 6b6aB-4k0xA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		7 / 12 SER A  79
SER A 126
ARG A 259
LYS A 216
THR A 217
GLY A 218
ASP A 222
 KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
None
 0.80A 6b6aD-4k0xA:
19.1		 6b6aD-4k0xA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  79
SER A 126
ARG A 259
LYS A 216
THR A 217
GLY A 218
 KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
 0.83A 6b6cA-4k0xA:
19.3		 6b6cA-4k0xA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  79
SER A 126
ARG A 259
LYS A 216
THR A 217
GLY A 218
 KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
 0.78A 6b6eA-4k0xA:
19.2		 6b6eA-4k0xA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 4k0x BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  79
SER A 126
LYS A 216
THR A 217
GLY A 218
ASP A 222
 KCX  A  82 (-2.5A)
BCT  A 301 (-2.8A)
BCT  A 301 (-3.0A)
BCT  A 301 (-3.5A)
BCT  A 301 (-3.4A)
None
 0.79A 6b6fA-4k0xA:
18.9		 6b6fA-4k0xA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 GLN A 143
HIS A 165
HIS A 167
LEU A 251
THR A 252
THR A 253
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
 1.18A 6bbsA-4xz5A:
24.9		 6bbsA-4xz5A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		5 / 12 HIS A 172
HIS A 167
THR A 253
THR A 252
TRP A  78
 None
ZN  A 401 ( 3.3A)
BCT  A 402 ( 4.4A)
BCT  A 402 (-3.7A)
None
 1.24A 6bbsA-4xz5A:
24.9		 6bbsA-4xz5A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 12 TRP A  78
ASN A 138
HIS A 140
GLN A 163
HIS A 165
HIS A 167
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
None
None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 0.55A 6bbsA-4xz5A:
24.9		 6bbsA-4xz5A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 TRP A  78
HIS A 140
HIS A 165
THR A 252
THR A 253
TRP A 262
 None
None
ZN  A 401 ( 3.2A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.32A 6bbsA-4xz5A:
24.9		 6bbsA-4xz5A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		11 / 12 TRP A  78
ASN A 138
GLN A 163
HIS A 165
HIS A 167
VAL A 186
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 None
None
None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 0.45A 6bc9A-4xz5A:
29.8		 6bc9A-4xz5A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 TRP A  78
HIS A 165
LEU A 251
THR A 253
PRO A 255
TRP A 262
 None
ZN  A 401 ( 3.2A)
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
None
None
 1.22A 6bc9A-4xz5A:
29.8		 6bc9A-4xz5A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 TRP A  78
HIS A 167
LEU A 251
THR A 252
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.3A)
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.25A 6bc9A-4xz5A:
29.8		 6bc9A-4xz5A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 TRP A  78
HIS A 167
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
 None
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
 1.14A 6bc9A-4xz5A:
29.8		 6bc9A-4xz5A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		7 / 12 TRP A  89
HIS A 165
HIS A 167
VAL A 186
LEU A 251
THR A 253
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
None
 1.46A 6bc9A-4xz5A:
29.8		 6bc9A-4xz5A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		10 / 12 GLN A 163
HIS A 165
HIS A 167
VAL A 186
VAL A 196
LEU A 251
THR A 252
THR A 253
PRO A 255
TRP A 262
 None
ZN  A 401 ( 3.2A)
ZN  A 401 ( 3.3A)
None
None
BCT  A 402 (-3.8A)
BCT  A 402 (-3.7A)
BCT  A 402 ( 4.4A)
None
None
 0.38A 6bccA-4xz5A:
29.8		 6bccA-4xz5A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 4xz5 CARBONIC ANHYDRASE,
ALPHA FAMILY
(Hydrogenovibrio
crunogenus) 		6 / 12 HIS A 165
VAL A 196
LEU A 251
THR A 253
PRO A 255
TRP A 262
 ZN  A 401 ( 3.2A)
None
BCT  A 402 (-3.8A)
BCT  A 402 ( 4.4A)
None
None
 1.31A 6bccA-4xz5A:
29.8		 6bccA-4xz5A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 5bxi NUCLEOSIDE
DIPHOSPHATE KINASE
(Toxoplasma
gondii) 		4 / 6 GLN A  32
VAL A 152
LEU A 106
ARG A  90
 None
None
None
BCT  A 201 ( 4.9A)
 1.17A 6brdB-5bxiA:
undetectable		 6brdB-5bxiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 2bgs ALDOSE REDUCTASE
(Hordeum
vulgare) 		4 / 5 GLU A 221
VAL A 294
LEU A 295
HIS A 121
 None
None
NDP  A1321 (-4.8A)
BCT  A1322 ( 3.9A)
 1.19A 6dyoA-2bgsA:
undetectable		 6dyoA-2bgsA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5bxi NUCLEOSIDE
DIPHOSPHATE KINASE
(Toxoplasma
gondii) 		4 / 6 VAL A  13
LEU A  93
LEU A 106
ARG A 107
 None
None
None
BCT  A 201 (-4.6A)
 0.72A 6e43A-5bxiA:
undetectable		 6e43A-5bxiA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5bxi NUCLEOSIDE
DIPHOSPHATE KINASE
(Toxoplasma
gondii) 		4 / 6 VAL A  13
LEU A  93
LEU A 106
ARG A 107
 None
None
None
BCT  A 201 (-4.6A)
 0.73A 6e43B-5bxiA:
undetectable		 6e43B-5bxiA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5bxi NUCLEOSIDE
DIPHOSPHATE KINASE
(Toxoplasma
gondii) 		4 / 6 VAL A  13
LEU A  93
LEU A 106
ARG A 107
 None
None
None
BCT  A 201 (-4.6A)
 0.75A 6e43C-5bxiA:
undetectable		 6e43C-5bxiA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5bxi NUCLEOSIDE
DIPHOSPHATE KINASE
(Toxoplasma
gondii) 		4 / 6 VAL A  13
LEU A  93
LEU A 106
ARG A 107
 None
None
None
BCT  A 201 (-4.6A)
 0.82A 6e43D-5bxiA:
undetectable		 6e43D-5bxiA:
17.28