SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BCR'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.00A 1c8lA-2zt9A:
undetectable		 1c8lA-2zt9A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1q90 CYTOCHROME B6F
COMPLEX SUBUNIT PETG
(Chlamydomonas
reinhardtii) 		4 / 4 THR G  17
LEU G  13
VAL G  10
LEU G   6
 BCR  B 904 ( 4.4A)
BCR  B 904 ( 4.3A)
None
None
 0.98A 1fbmD-1q90G:
undetectable		 1fbmD-1q90G:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.01A 1gfzA-2zt9A:
undetectable		 1gfzA-2zt9A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.04A 1l5qA-2zt9A:
undetectable		 1l5qA-2zt9A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.03A 1l5qB-2zt9A:
undetectable		 1l5qB-2zt9A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.02A 1l7xA-2zt9A:
undetectable		 1l7xA-2zt9A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.06A 1l7xB-2zt9A:
undetectable		 1l7xB-2zt9A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Pisum
sativum) 		4 / 4 HIS B 389
ALA B 388
PHE B 387
GLY B 335
 CLA  B1226 (-4.0A)
CLA  B1226 ( 4.2A)
BCR  B6010 ( 3.2A)
BCR  B6010 ( 4.3A)
 1.11A 1mj2B-4rkuB:
undetectable		 1mj2B-4rkuB:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Pisum
sativum) 		4 / 4 HIS B 389
ALA B 388
PHE B 387
GLY B 335
 CLA  B1226 (-4.0A)
CLA  B1226 ( 4.2A)
BCR  B6010 ( 3.2A)
BCR  B6010 ( 4.3A)
 1.06A 1mj2D-4rkuB:
undetectable		 1mj2D-4rkuB:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS b 387
ALA b 386
PHE b 385
GLY b 333
 CLA  b1832 (-3.9A)
CLA  b1832 ( 3.9A)
BCR  b1848 ( 3.3A)
BCR  b1848 ( 4.4A)
 1.11A 1mj2D-5oy0b:
undetectable		 1mj2D-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 4 HIS B 387
ALA B 386
PHE B 385
GLY B 333
 CLA  B1226 (-4.1A)
CLA  B1226 ( 4.4A)
BCR  B4008 (-4.8A)
BCR  B4008 ( 4.6A)
 1.39A 1mj2D-6fosB:
undetectable		 1mj2D-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Pisum
sativum) 		4 / 4 HIS B 389
ALA B 388
PHE B 387
GLY B 335
 CLA  B1226 (-4.0A)
CLA  B1226 ( 4.2A)
BCR  B6010 ( 3.2A)
BCR  B6010 ( 4.3A)
 1.09A 1mjoB-4rkuB:
undetectable		 1mjoB-4rkuB:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Pisum
sativum) 		4 / 4 HIS B 389
ALA B 388
PHE B 387
GLY B 335
 CLA  B1226 (-4.0A)
CLA  B1226 ( 4.2A)
BCR  B6010 ( 3.2A)
BCR  B6010 ( 4.3A)
 1.09A 1mjoA-4rkuB:
undetectable		 1mjoA-4rkuB:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Synechocystis
sp.
PCC
6803) 		4 / 4 HIS b 387
ALA b 386
PHE b 385
GLY b 333
 CLA  b1832 (-3.9A)
CLA  b1832 ( 3.9A)
BCR  b1848 ( 3.3A)
BCR  b1848 ( 4.4A)
 1.14A 1mjoA-5oy0b:
undetectable		 1mjoA-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)		 4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Pisum
sativum) 		4 / 4 HIS B 389
ALA B 388
PHE B 387
GLY B 335
 CLA  B1226 (-4.0A)
CLA  B1226 ( 4.2A)
BCR  B6010 ( 3.2A)
BCR  B6010 ( 4.3A)
 1.09A 1mjoD-4rkuB:
undetectable		 1mjoD-4rkuB:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Pisum
sativum) 		5 / 12 LEU A 346
PHE A 417
ILE A 349
TYR A 428
TYR A 422
 CLA  A1122 ( 4.7A)
BCR  A6007 ( 4.3A)
None
None
None
 1.46A 1osvB-4rkuA:
undetectable		 1osvB-4rkuA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)		 4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Pisum
sativum) 		5 / 12 LEU A 346
PHE A 417
ILE A 349
TYR A 428
TYR A 422
 CLA  A1122 ( 4.7A)
BCR  A6007 ( 4.3A)
None
None
None
 1.50A 1ot7B-4rkuA:
undetectable		 1ot7B-4rkuA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)		 5fcy RED CAROTENOID
PROTEIN (RCP)
(Nostoc
sp.
PCC
7120) 		5 / 12 PHE A 101
LEU A  74
TYR A  90
LEU A  27
MET A 109
 None
None
None
BCR  A 201 (-3.8A)
BCR  A 201 (-2.8A)
 1.42A 1p33B-5fcyA:
undetectable		 1p33B-5fcyA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Pisum
sativum) 		4 / 4 ALA A 414
VAL A 560
ALA A 415
HIS A 355
 BCR  A6007 ( 3.8A)
None
None
CLA  A1103 (-3.6A)
 1.23A 1q23F-4rkuA:
undetectable		 1q23F-4rkuA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		3 / 3 VAL L 126
ALA L 125
HIS L  54
 None
None
BCR  L 205 (-3.9A)
 0.57A 1q23G-5zgbL:
undetectable		 1q23G-5zgbL:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		3 / 3 VAL L 126
ALA L 125
HIS L  54
 None
None
BCR  L 205 (-3.9A)
 0.68A 1q23L-5zgbL:
undetectable		 1q23L-5zgbL:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		3 / 3 VAL L 126
ALA L 125
HIS L  54
 None
None
BCR  L 205 (-3.9A)
 0.58A 1q23J-5zgbL:
undetectable		 1q23J-5zgbL:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY 1 408
HIS 1 407
SER 1  69
ASP 1 415
VAL 1 553
 BCR  1 847 (-3.6A)
CLA  1 830 (-3.9A)
CLA  1 825 ( 4.1A)
None
BCR  1 848 (-4.8A)
 1.29A 1qu3A-5oy01:
undetectable		 1qu3A-5oy01:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Pisum
sativum) 		5 / 11 VAL A 553
THR A 552
ALA A 363
ILE A 360
ALA A 414
 BCR  A6008 (-3.9A)
CLA  A1124 (-3.5A)
BCR  A6008 (-3.7A)
BCR  A6007 ( 4.5A)
BCR  A6007 ( 3.8A)
 1.15A 2admB-4rkuA:
undetectable		 2admB-4rkuA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		5 / 12 LEU L  89
GLY L  51
ALA L 125
GLY L 130
ILE L  86
 BCR  L 205 (-3.7A)
None
None
None
None
 0.88A 2avsA-5zgbL:
undetectable		 2avsA-5zgbL:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 2wsc PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 8 PHE L 143
LEU L  95
LEU L  64
LEU L  63
 None
BCR  L1169 ( 3.8A)
None
None
 1.00A 2bfpB-2wscL:
undetectable		 2bfpB-2wscL:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 5zgb PSAK
(Cyanidioschyzon
merolae) 		5 / 12 GLY K  24
GLY K  20
ALA K  38
THR K  34
ALA K  27
 None
None
BCR  K 101 (-3.8A)
None
BCR  K 101 ( 3.7A)
 1.00A 2gluB-5zgbK:
undetectable		 2gluB-5zgbK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Pisum
sativum) 		5 / 12 MET A 418
ALA A 356
SER A 359
LEU A 432
ILE A 349
 None
BCR  A6007 ( 3.8A)
BCR  A6008 ( 3.7A)
CLA  A1122 ( 4.8A)
None
 1.15A 2h77A-4rkuA:
undetectable		 2h77A-4rkuA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		5 / 12 LEU L  89
GLY L  51
ALA L 125
ILE L  83
ILE L  86
 BCR  L 205 (-3.7A)
None
None
None
None
 0.82A 2hs1B-5zgbL:
undetectable		 2hs1B-5zgbL:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		5 / 12 LEU L  89
GLY L  51
ALA L 125
ILE L  83
ILE L  86
 BCR  L 205 (-3.7A)
None
None
None
None
 0.81A 2rkfA-5zgbL:
undetectable		 2rkfA-5zgbL:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		5 / 12 LEU L  89
GLY L  51
ALA L 125
ILE L  83
ILE L  86
 BCR  L 205 (-3.7A)
None
None
None
None
 0.90A 2rkgB-5zgbL:
undetectable		 2rkgB-5zgbL:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		4 / 6 LEU B 173
SER B 327
PHE B 330
ASP B 395
 None
None
BCR  B4008 (-4.5A)
None
 1.33A 2vn1B-6fosB:
undetectable		 2vn1B-6fosB:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL 1 678
PHE 1 742
SER 1 610
VAL 1 737
TYR 1 599
 BCR  1 856 (-4.9A)
CLA  1 801 (-3.4A)
None
BCR  1 856 (-3.7A)
CLA  1 801 (-4.5A)
 1.25A 2y01A-5oy01:
undetectable		 2y01A-5oy01:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		4 / 6 ILE A 407
TYR A 408
LEU A 184
PHE A 187
 None
BCR  A4007 (-4.5A)
None
None
 1.06A 3adsA-6fosA:
undetectable		 3adsA-6fosA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 5 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.00A 3bcrA-2zt9A:
undetectable		 3bcrA-2zt9A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		4 / 4 GLY 0 134
GLY 0 131
GLY 0  54
GLY 0  58
 BCR  0 205 ( 4.0A)
None
None
None
 0.66A 3bogC-5oy00:
undetectable		 3bogC-5oy00:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		4 / 4 GLY 0 134
GLY 0 131
GLY 0  54
GLY 0  58
 BCR  0 205 ( 4.0A)
None
None
None
 0.64A 3bogD-5oy00:
undetectable		 3bogD-5oy00:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU 0 141
LEU 0 142
GLN 0  77
LEU 0  67
TYR 0  59
 CLA  0 203 ( 4.2A)
CLA  0 203 (-4.6A)
None
CLA  0 203 (-4.1A)
BCR  0 205 (-4.0A)
 1.29A 3d90B-5oy00:
undetectable		 3d90B-5oy00:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.02A 3dd1A-2zt9A:
undetectable		 3dd1A-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.03A 3dd1B-2zt9A:
undetectable		 3dd1B-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.03A 3ddsA-2zt9A:
undetectable		 3ddsA-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.03A 3ddsB-2zt9A:
undetectable		 3ddsB-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.02A 3ddwA-2zt9A:
undetectable		 3ddwA-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120) 		4 / 6 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.01A 3ddwB-2zt9A:
undetectable		 3ddwB-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_1
(GLUCOCORTICOID
RECEPTOR)		 5fcy RED CAROTENOID
PROTEIN (RCP)
(Nostoc
sp.
PCC
7120) 		5 / 10 TRP A 102
MET A 153
GLN A  73
LEU A  74
LEU A  27
 None
None
None
None
BCR  A 201 (-3.8A)
 1.21A 3h52B-5fcyA:
undetectable		 3h52B-5fcyA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120) 		5 / 9 MET A  96
LEU G  13
SER A  89
VAL B  43
GLY B  46
 OPC  H  30 ( 3.9A)
BCR  G 101 ( 4.0A)
None
BCR  G 101 ( 3.9A)
BCR  G 101 ( 4.7A)
 1.41A 3hcoA-2zt9A:
undetectable		 3hcoA-2zt9A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 4
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
(Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120;
Nostoc
sp.
PCC
7120) 		5 / 10 MET A  96
LEU G  13
SER A  89
VAL B  43
GLY B  46
 OPC  H  30 ( 3.9A)
BCR  G 101 ( 4.0A)
None
BCR  G 101 ( 3.9A)
BCR  G 101 ( 4.7A)
 1.42A 3hcoB-2zt9A:
undetectable		 3hcoB-2zt9A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4fe1 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Thermosynechococ
cus
elongatus) 		5 / 12 PHE L 124
GLY L  51
ALA L  84
GLY L  55
LEU L  58
 BCR  L1005 (-4.3A)
None
None
None
None
 0.99A 3hs6B-4fe1L:
0.7		 3hs6B-4fe1L:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		5 / 12 PHE 0 127
GLY 0  54
ALA 0  87
GLY 0  58
LEU 0  61
 BCR  0 204 (-4.0A)
None
None
None
None
 0.97A 3hs6B-5oy00:
1.2		 3hs6B-5oy00:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		5 / 9 LEU L  89
GLY L  51
ALA L 125
ILE L  83
ILE L  86
 BCR  L 205 (-3.7A)
None
None
None
None
 0.87A 3nu4B-5zgbL:
undetectable		 3nu4B-5zgbL:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		5 / 10 LEU L  89
GLY L  51
ALA L 125
ILE L  83
ILE L  86
 BCR  L 205 (-3.7A)
None
None
None
None
 0.86A 3s43B-5zgbL:
undetectable		 3s43B-5zgbL:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		5 / 11 LEU L  89
GLY L  51
ALA L 125
ILE L  83
ILE L  86
 BCR  L 205 (-3.7A)
None
None
None
None
 0.84A 3s45B-5zgbL:
undetectable		 3s45B-5zgbL:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 5zji PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Zea
mays) 		5 / 9 GLY L 130
ALA L 131
GLY L 124
LEU L 195
VAL L 194
 BCR  L 301 ( 4.0A)
None
None
None
None
 1.02A 3u7sB-5zjiL:
undetectable		 3u7sB-5zjiL:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		4 / 8 TYR L  37
LEU L 117
MET L  93
TRP L 114
 None
None
BCR  L 205 (-3.4A)
None
 1.16A 3uzzB-5zgbL:
undetectable		 3uzzB-5zgbL:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 4xk8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pisum
sativum) 		5 / 12 GLY L  85
ALA L  83
ILE L 144
LEU L  60
VAL L 147
 None
BCR  L 201 ( 3.9A)
None
None
None
 0.87A 4azsA-4xk8L:
undetectable		 4azsA-4xk8L:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 4xk8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pisum
sativum) 		5 / 12 GLY L  85
ALA L  83
ILE L 144
LEU L  60
VAL L 147
 None
BCR  L 201 ( 3.9A)
None
None
None
 0.89A 4aztA-4xk8L:
undetectable		 4aztA-4xk8L:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 4xk8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pisum
sativum) 		5 / 12 GLY L  85
ALA L  83
ILE L 144
LEU L  60
VAL L 147
 None
BCR  L 201 ( 3.9A)
None
None
None
 0.87A 4azvA-4xk8L:
undetectable		 4azvA-4xk8L:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 4xk8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pisum
sativum) 		5 / 12 GLY L  85
ALA L  83
ILE L 144
LEU L  60
VAL L 147
 None
BCR  L 201 ( 3.9A)
None
None
None
 0.89A 4azwA-4xk8L:
undetectable		 4azwA-4xk8L:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3a0b PHOTOSYSTEM II
REACTION CENTER
PROTEIN K
PHOTOSYSTEM II
REACTION CENTER
PROTEIN YCF12
(Thermosynechococ
cus
vulcanus) 		4 / 8 LEU K  31
VAL K  27
VAL K  24
GLN Y  21
 BCR  K1051 ( 4.4A)
None
None
None
 1.00A 4em2A-3a0bK:
undetectable		 4em2A-3a0bK:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY 0 133
GLY 0 131
GLY 0 130
LEU 0  51
GLY 0  58
 BCR  0 205 (-3.5A)
None
None
CLA  0 201 ( 4.8A)
None
 0.90A 4o33A-5oy00:
undetectable		 4o33A-5oy00:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY 0 133
GLY 0 131
GLY 0 130
LEU 0  51
GLY 0  58
 BCR  0 205 (-3.5A)
None
None
CLA  0 201 ( 4.8A)
None
 0.75A 4o3fA-5oy00:
undetectable		 4o3fA-5oy00:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		5 / 12 GLY B 383
GLY B 333
ILE B 381
ILE B 390
ALA B 386
 CLA  B1226 (-3.4A)
BCR  B4008 ( 4.6A)
CLA  B1222 (-3.7A)
CLA  B1226 (-4.3A)
CLA  B1226 ( 4.4A)
 1.07A 4qtuD-6fosB:
undetectable		 4qtuD-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 4xk8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pisum
sativum) 		5 / 12 GLY L  85
ALA L  83
ILE L 144
LEU L  60
VAL L 147
 None
BCR  L 201 ( 3.9A)
None
None
None
 1.05A 4uw0A-4xk8L:
undetectable		 4uw0A-4xk8L:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1q90 CYTOCHROME B6
CYTOCHROME B6F
COMPLEX SUBUNIT PETG
CYTOCHROME B6F
COMPLEX SUBUNIT PETL
CYTOCHROME B6F
COMPLEX SUBUNIT PETM
(Chlamydomonas
reinhardtii) 		5 / 12 TYR L   7
PHE B  33
GLY G  20
LEU M  78
THR M  72
 LMG  L 951 (-3.4A)
BCR  B 904 (-4.5A)
BCR  B 904 (-3.4A)
None
LMG  L 951 (-3.8A)
 1.18A 4ze1A-1q90L:
undetectable		 4ze1A-1q90L:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Cyanidioschyzon
merolae) 		5 / 11 ALA A 347
LEU A 337
LEU A 341
LEU A 423
MET A 426
 BCR  A4007 ( 4.9A)
CLA  A1122 ( 4.4A)
CLA  A1123 (-3.8A)
BCR  A4007 ( 4.7A)
CLA  A1129 (-3.4A)
 1.36A 4zn7B-6fosA:
1.9		 4zn7B-6fosA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY 1 405
GLY 1 408
ILE 1 401
LEU 1 549
ALA 1 556
 BCR  1 848 ( 3.9A)
BCR  1 847 (-3.6A)
CLA  1 826 ( 3.7A)
BCR  1 848 (-3.9A)
None
 1.16A 5bw4B-5oy01:
undetectable		 5bw4B-5oy01:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		5 / 12 LEU L  89
GLY L  51
ALA L 125
ILE L  83
ILE L  86
 BCR  L 205 (-3.7A)
None
None
None
None
 0.83A 5e5jA-5zgbL:
undetectable		 5e5jA-5zgbL:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		5 / 12 LEU L  89
GLY L  51
ALA L 125
ILE L  83
ILE L  86
 BCR  L 205 (-3.7A)
None
None
None
None
 0.86A 5e5kB-5zgbL:
undetectable		 5e5kB-5zgbL:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Pisum
sativum) 		5 / 12 ILE A 569
HIS A 597
ALA A 414
ALA A 415
VAL A 419
 None
None
BCR  A6007 ( 3.8A)
None
None
 1.04A 5igtA-4rkuA:
undetectable		 5igtA-4rkuA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_F_AZ1F2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR-DAR)		 4xk8 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pisum
sativum) 		5 / 7 GLY L  49
GLY L 142
SER L 145
GLY L 143
VAL L  52
 None
None
BCR  L 206 (-3.2A)
None
CLA  L 203 (-3.3A)
 1.32A 5izjB-4xk8L:
undetectable		 5izjB-4xk8L:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Pisum
sativum) 		4 / 6 THR B 720
GLY B 653
PHE B 652
ILE A 462
 CLA  B9010 (-3.5A)
None
BCR  A6017 ( 4.5A)
CLA  A1132 ( 4.1A)
 0.94A 5kmfA-4rkuB:
undetectable
5kmfC-4rkuB:
2.9		 5kmfA-4rkuB:
17.30
5kmfC-4rkuB:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2
(Cyanidioschyzon
merolae) 		3 / 3 SER B 340
SER B 344
PHE B 385
 None
CLA  B1222 (-3.3A)
BCR  B4008 (-4.8A)
 0.93A 5mugA-6fosB:
undetectable		 5mugA-6fosB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 5zgb PSAL
(Cyanidioschyzon
merolae) 		5 / 12 LEU L  89
GLY L  51
ALA L 125
ILE L  83
ILE L  86
 BCR  L 205 (-3.7A)
None
None
None
None
 0.83A 5t8hA-5zgbL:
undetectable		 5t8hA-5zgbL:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5oy0 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Synechocystis
sp.
PCC
6803) 		4 / 8 VAL 0  53
LEU 0  96
THR 0  93
ALA 0  92
 CLA  0 202 (-3.1A)
BCR  0 204 (-4.0A)
None
BCR  0 204 ( 3.5A)
 0.90A 5tt3H-5oy00:
undetectable		 5tt3H-5oy00:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W8A_A_SAMA300_0
(AUTOINDUCER SYNTHASE)		 5fcy RED CAROTENOID
PROTEIN (RCP)
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 105
TYR A  90
MET A 153
VAL A 150
ILE A  79
 BCR  A 201 ( 3.9A)
None
None
None
None
 1.41A 5w8aA-5fcyA:
undetectable		 5w8aA-5fcyA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 4fe1 PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Thermosynechococ
cus
elongatus) 		5 / 12 LEU L  85
ILE L  83
ILE L  59
VAL L  88
ALA L  89
 None
None
None
None
BCR  L1005 ( 3.5A)
 0.96A 6ajiA-4fe1L:
undetectable		 6ajiA-4fe1L:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
(Synechocystis
sp.
PCC
6803) 		5 / 12 ASP 1 589
SER 1 586
VAL 1 402
GLY 1 405
ALA 1 409
 None
None
CLA  1 830 ( 4.7A)
BCR  1 848 ( 3.9A)
None
 1.12A 6bqgA-5oy01:
1.7		 6bqgA-5oy01:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 5zji PHOTOSYSTEM I
REACTION CENTER
SUBUNIT VI,
CHLOROPLASTIC
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT XI
(Zea
mays) 		5 / 12 PHE H  94
GLY L 133
THR L 183
GLY L 184
GLY L 185
 None
BCR  L 301 ( 4.7A)
None
None
None
 0.93A 6brdB-5zjiH:
undetectable		 6brdB-5zjiH:
17.28