SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BCP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1m66 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Leishmania
mexicana) 		4 / 5 VAL A  43
PHE A 101
ILE A  93
PHE A 102
 None
BCP  A 401 ( 4.9A)
BCP  A 401 (-4.0A)
None
 1.13A 3owxB-1m66A:
5.3		 3owxB-1m66A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1m66 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
(Leishmania
mexicana) 		5 / 12 GLU A  50
PHE A  91
ILE A  89
PHE A 101
GLY A 106
 None
None
None
BCP  A 401 ( 4.9A)
None
 1.31A 5esgA-1m66A:
undetectable		 5esgA-1m66A:
22.01