SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BCL'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 12 LEU M 607
HIS M 487
LEU M 491
HIS M 515
PHE M 519
 BCL  M 702 (-4.5A)
None
None
None
BCL  M 702 ( 4.4A)
 1.35A 1d4fC-5yq7M:
undetectable		 1d4fC-5yq7M:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 3eni BACTERIOCHLOROPHYLL
A PROTEIN
(Chlorobaculum
tepidum) 		4 / 7 SER A 117
SER A 220
ARG A 221
LEU A 207
 None
BCL  A 371 ( 3.8A)
None
None
 1.08A 1ibgL-3eniA:
undetectable		 1ibgL-3eniA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 1lgh LIGHT HARVESTING
COMPLEX II
(Phaeospirillum
molischianum) 		3 / 3 ALA B  34
HIS B  35
VAL B  38
 BCL  A  57 ( 3.7A)
BCL  B  59 (-3.5A)
DET  B  77 ( 4.5A)
 0.32A 1lqtB-1lghB:
undetectable		 1lqtB-1lghB:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 1lgh LIGHT HARVESTING
COMPLEX II
(Phaeospirillum
molischianum) 		3 / 3 ALA B  34
HIS B  35
VAL B  38
 BCL  A  57 ( 3.7A)
BCL  B  59 (-3.5A)
DET  B  77 ( 4.5A)
 0.32A 1lquB-1lghB:
undetectable		 1lquB-1lghB:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3eni BACTERIOCHLOROPHYLL
A PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLY A 116
GLU A 115
GLY A  99
ASP A 146
ASN A 120
 BCL  A 376 ( 4.0A)
None
None
None
None
 1.24A 1n2xA-3eniA:
undetectable		 1n2xA-3eniA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		5 / 12 GLY A 116
GLU A 115
GLY A  99
ASP A 146
ASN A 120
 BCL  A 376 ( 4.1A)
None
EDO  A 385 ( 4.0A)
None
None
 1.32A 1n2xA-3eojA:
undetectable		 1n2xA-3eojA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 3eni BACTERIOCHLOROPHYLL
A PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 GLY A 355
ASP A 233
SER A 236
ILE A 235
GLY A 196
 None
BCL  A 375 ( 4.6A)
None
None
None
 1.16A 1q8jB-3eniA:
undetectable		 1q8jB-3eniA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		4 / 7 ASP A 154
ASN A 155
PHE A 108
SER A 111
 NA  A1232 ( 4.9A)
None
BCL  A 371 (-4.2A)
EDO  A 383 ( 4.3A)
 1.43A 1rqpB-3eojA:
undetectable		 1rqpB-3eojA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3eni BACTERIOCHLOROPHYLL
A PROTEIN
(Chlorobaculum
tepidum) 		5 / 12 LEU A 241
ASP A 233
ILE A 292
HIS A 226
GLN A 197
 BCL  A 375 (-3.7A)
BCL  A 375 ( 4.6A)
BCL  A 377 ( 4.8A)
BCL  A 376 (-3.4A)
BCL  A 377 (-3.1A)
 1.24A 1s9aB-3eniA:
undetectable		 1s9aB-3eniA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1nkz LIGHT-HARVESTING
PROTEIN B-800/850,
ALPHA CHAIN
LIGHT-HARVESTING
PROTEIN B-800/850,
BETA CHAIN
(Rhodoblastus
acidophilus) 		3 / 3 LEU A  19
HIS B  12
ILE A   6
 None
CXM  A   1 ( 4.0A)
BCL  A 307 ( 4.1A)
 0.62A 1s9pB-1nkzA:
undetectable		 1s9pB-1nkzA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1eys PHOTOSYNTHETIC
REACTION CENTER
(Thermochromatium
tepidum) 		4 / 6 ALA L 101
TYR L 156
TYR L 136
ILE L  97
 BPH  L 606 ( 3.9A)
BPH  L 606 (-3.7A)
BCL  L 604 ( 4.4A)
None
 1.28A 2dcfA-1eysL:
0.0		 2dcfA-1eysL:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1eys PHOTOSYNTHETIC
REACTION CENTER
(Thermochromatium
tepidum) 		4 / 6 LEU L 139
ASN L 178
GLN L 171
PHE L 154
 BCL  L 602 (-4.4A)
None
None
BCL  L 604 (-3.5A)
 1.21A 2jn3A-1eysL:
0.0		 2jn3A-1eysL:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 1eys PHOTOSYNTHETIC
REACTION CENTER
(Thermochromatium
tepidum) 		4 / 8 ALA L 248
GLY L 134
SER L 252
ALA L 253
 None
None
BCL  L 602 (-3.2A)
BCL  L 602 ( 4.9A)
 0.79A 2vh3B-1eysL:
0.0		 2vh3B-1eysL:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 3eni BACTERIOCHLOROPHYLL
A PROTEIN
(Chlorobaculum
tepidum) 		4 / 9 ALA A 345
VAL A 348
CYH A 352
LYS A 353
 None
BCL  A 374 ( 4.1A)
BCL  A 373 ( 3.8A)
None
 0.50A 2vufB-3eniA:
undetectable		 2vufB-3eniA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		4 / 9 ALA A 346
VAL A 349
CYH A 353
LYS A 354
 None
BCL  A 374 ( 4.0A)
BCL  A 373 ( 3.8A)
None
 0.52A 2vufB-3eojA:
2.3		 2vufB-3eojA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		4 / 7 ILE M 505
LEU M 489
PHE M 486
LEU M 479
 BPH  M 703 (-4.1A)
None
None
BCL  M 702 (-4.6A)
 0.87A 3adxA-5yq7M:
undetectable		 3adxA-5yq7M:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3eni BACTERIOCHLOROPHYLL
A PROTEIN
(Chlorobaculum
tepidum) 		4 / 5 ILE A 235
HIS A 226
TYR A 123
ARG A 198
 None
BCL  A 376 (-3.4A)
BCL  A 378 (-4.6A)
None
 1.25A 3b9mA-3eniA:
undetectable		 3b9mA-3eniA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		4 / 5 ILE A 236
HIS A 227
TYR A 123
ARG A 199
 None
BCL  A 376 (-3.5A)
BCL  A 378 (-4.6A)
EDO  A 379 ( 3.5A)
 1.23A 3b9mA-3eojA:
undetectable		 3b9mA-3eojA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		5 / 12 ALA A 192
ILE A 293
PHE A 185
SER A 235
ILE A 200
 BCL  A 377 (-3.6A)
None
BCL  A 377 ( 4.2A)
BCL  A 376 ( 3.9A)
EDO  A 381 (-4.8A)
 1.12A 3clbB-3eojA:
undetectable		 3clbB-3eojA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 THR L 182
LEU L 236
ALA L 240
SER L 239
 BCL  M   1 (-3.8A)
None
None
None
 0.75A 3kp6A-1pssL:
undetectable		 3kp6A-1pssL:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		3 / 3 PHE L 167
CYH L 247
HIS L 173
 BCL  L   2 (-4.1A)
BCL  L   2 (-3.2A)
BCL  L   2 (-3.7A)
 1.30A 3u9fL-1pssL:
undetectable		 3u9fL-1pssL:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1pss PHOTOSYNTHETIC
REACTION CENTER
PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		5 / 12 PHE L 146
TYR M 210
SER L 244
MET L 248
LEU L 131
 BCL  M   4 (-3.5A)
BCL  L   2 (-3.9A)
BCL  L   2 (-3.2A)
BCL  L   2 (-3.4A)
BCL  L   2 ( 4.3A)
 1.32A 4a83A-1pssL:
undetectable		 4a83A-1pssL:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		5 / 10 SER A  24
ALA A 252
LEU A 273
GLY A 275
ALA A  33
 None
BCL  A 376 ( 3.8A)
BCL  A 376 ( 4.2A)
BCL  A 375 ( 3.8A)
BCL  A 373 (-3.5A)
 1.47A 4fe1A-3eojA:
undetectable
4fe1J-3eojA:
undetectable		 4fe1A-3eojA:
19.24
4fe1J-3eojA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		5 / 9 SER A  24
ALA A 252
LEU A 273
GLY A 275
ALA A  33
 None
BCL  A 376 ( 3.8A)
BCL  A 376 ( 4.2A)
BCL  A 375 ( 3.8A)
BCL  A 373 (-3.5A)
 1.20A 4l6va-3eojA:
undetectable
4l6vf-3eojA:
undetectable		 4l6va-3eojA:
17.51
4l6vf-3eojA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 1eys PHOTOSYNTHETIC
REACTION CENTER
(Thermochromatium
tepidum) 		3 / 3 SER L 166
ASP L 163
GLN C 239
 BCL  L 602 ( 4.3A)
None
None
 0.92A 4oltA-1eysL:
1.7
4oltB-1eysL:
0.5		 4oltA-1eysL:
23.02
4oltB-1eysL:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 1eys PHOTOSYNTHETIC
REACTION CENTER
(Thermochromatium
tepidum) 		3 / 3 GLN C 239
SER L 166
ASP L 163
 None
BCL  L 602 ( 4.3A)
None
 0.89A 4qwpA-1eysC:
0.0
4qwpB-1eysC:
0.0		 4qwpA-1eysC:
22.03
4qwpB-1eysC:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1eys PHOTOSYNTHETIC
REACTION CENTER
(Thermochromatium
tepidum) 		5 / 8 ALA L 104
ALA L 101
ALA L 132
TYR L 136
LEU L 137
 BPH  L 606 ( 4.1A)
BPH  L 606 ( 3.9A)
BPH  L 606 (-3.7A)
BCL  L 604 ( 4.4A)
None
 1.46A 4v1fA-1eysL:
2.7
4v1fB-1eysL:
2.8		 4v1fA-1eysL:
16.07
4v1fB-1eysL:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1lgh LIGHT HARVESTING
COMPLEX II
(Phaeospirillum
molischianum) 		4 / 9 ALA B  15
LEU B   8
LEU A  11
ILE A   9
 LYC  A  97 ( 2.7A)
None
None
BCL  A  58 (-4.0A)
 0.85A 4xtaA-1lghB:
undetectable		 4xtaA-1lghB:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 1pss PHOTOSYNTHETIC
REACTION CENTER
(Rhodobacter
sphaeroides) 		4 / 8 PHE L 215
GLU L 212
HIS M 266
THR L 182
 None
U10  L 272 (-3.8A)
FE  M 302 (-3.3A)
BCL  M   1 (-3.8A)
 1.38A 5hqaA-1pssL:
undetectable		 5hqaA-1pssL:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 1eys PHOTOSYNTHETIC
REACTION CENTER
(Thermochromatium
tepidum) 		5 / 12 ALA L 180
HIS L 181
LEU L 183
ALA L 184
PHE L 187
 None
BCL  L 602 (-4.0A)
BGL  L 701 (-3.3A)
BCL  L 602 (-3.5A)
None
 0.67A 5k9dA-1eysL:
0.0		 5k9dA-1eysL:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_B_PFLB410_1
(PROTON-GATED ION
CHANNEL)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		5 / 9 TYR A 364
ILE A 287
ILE A 315
VAL A 276
ILE A  18
 None
BCL  A 374 ( 4.3A)
None
BCL  A 375 ( 4.5A)
None
 1.48A 5mvnB-3eojA:
2.6		 5mvnB-3eojA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		5 / 10 TYR A 364
ILE A 287
ILE A 315
VAL A 276
ILE A  18
 None
BCL  A 374 ( 4.3A)
None
BCL  A 375 ( 4.5A)
None
 1.47A 5mvnD-3eojA:
2.6		 5mvnD-3eojA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA902_0
(PROTEIN ARGONAUTE-2)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		4 / 4 VAL A  63
ALA A  97
PHE A 243
PHE A  66
 EDO  A 392 (-4.7A)
BCL  A 376 (-3.6A)
BCL  A 375 (-4.4A)
BCL  A 375 (-4.6A)
 1.41A 6cbdA-3eojA:
0.0		 6cbdA-3eojA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 1lgh LIGHT HARVESTING
COMPLEX II
LIGHT HARVESTING
COMPLEX II
(Phaeospirillum
molischianum;
Phaeospirillum
molischianum) 		4 / 4 ILE A  13
LEU B   8
HIS B  17
ALA B  13
 None
None
BCL  A  58 ( 4.1A)
None
 1.04A 6ck2C-1lghA:
undetectable
6ck2D-1lghA:
undetectable		 6ck2C-1lghA:
8.93
6ck2D-1lghA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D6T_D_FYPD406_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
HUMAN GABA-A
RECEPTOR SUBUNIT
GAMMA-2)		 1nkz LIGHT-HARVESTING
PROTEIN B-800/850,
ALPHA CHAIN
LIGHT-HARVESTING
PROTEIN B-800/850,
BETA CHAIN
(Rhodoblastus
acidophilus;
Rhodoblastus
acidophilus) 		5 / 11 HIS A  31
THR B  37
TYR A  44
PHE A  41
THR A  38
 BCL  B 302 (-3.2A)
RG1  A 404 (-3.8A)
RG1  A 404 ( 3.8A)
BCL  A 301 (-4.0A)
None
 1.32A 6d6tD-1nkzA:
undetectable
6d6tE-1nkzA:
undetectable		 6d6tD-1nkzA:
9.04
6d6tE-1nkzA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3eni BACTERIOCHLOROPHYLL
A PROTEIN
(Chlorobaculum
tepidum) 		3 / 3 LEU A 294
GLY A 298
PHE A 306
 None
None
BCL  A 373 ( 3.8A)
 0.60A 6exiC-3eniA:
undetectable		 6exiC-3eniA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		3 / 3 LEU A 295
GLY A 299
PHE A 307
 None
None
BCL  A 373 ( 3.6A)
 0.60A 6exiC-3eojA:
undetectable		 6exiC-3eojA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		4 / 8 VAL A 232
HIS A 290
ASN A 289
GLU A 241
 EDO  A 389 ( 4.5A)
BCL  A 374 (-3.3A)
EDO  A 391 ( 4.4A)
BCL  A 375 ( 4.0A)
 1.07A 6gneB-3eojA:
undetectable		 6gneB-3eojA:
21.40