SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BCB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 6et5 LIGHT-HARVESTING
PROTEIN B-1015 BETA
CHAIN
LIGHT-HARVESTING
PROTEIN B-1015 GAMMA
CHAIN
(Blastochloris
viridis) 		5 / 10 VAL 1  36
GLY 2  25
ILE 2  29
ALA 1  31
ILE 1  35
 BCB  z 101 ( 4.4A)
None
None
None
None
 0.96A 3ekpB-6et51:
undetectable		 3ekpB-6et51:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 6et5 LIGHT-HARVESTING
PROTEIN B-1015 BETA
CHAIN
LIGHT-HARVESTING
PROTEIN B-1015 GAMMA
CHAIN
(Blastochloris
viridis) 		5 / 10 VAL 1  36
GLY 2  25
ILE 2  29
ALA 1  31
ILE 1  35
 BCB  z 101 ( 4.4A)
None
None
None
None
 0.97A 3ekpC-6et51:
undetectable		 3ekpC-6et51:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 6et5 LIGHT-HARVESTING
PROTEIN B-1015 BETA
CHAIN
LIGHT-HARVESTING
PROTEIN B-1015 GAMMA
CHAIN
(Blastochloris
viridis) 		5 / 9 VAL 1  36
GLY 2  25
ILE 2  29
ALA 1  31
ILE 1  35
 BCB  z 101 ( 4.4A)
None
None
None
None
 0.97A 3ektB-6et51:
undetectable		 3ektB-6et51:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 6et5 LIGHT-HARVESTING
PROTEIN B-1015 BETA
CHAIN
LIGHT-HARVESTING
PROTEIN B-1015 GAMMA
CHAIN
(Blastochloris
viridis) 		5 / 10 ILE 2  23
GLY 2  25
ILE 2  29
ALA 1  31
ILE 1  35
 BCB  z 101 (-3.7A)
None
None
None
None
 0.92A 3ekwA-6et52:
undetectable		 3ekwA-6et52:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3prc PHOTOSYNTHETIC
REACTION CENTER
(Blastochloris
viridis) 		4 / 5 LEU L  94
GLY L  95
PHE L  97
PHE L 128
 None
None
BCB  L 302 ( 3.8A)
None
 0.88A 3smtA-3prcL:
undetectable		 3smtA-3prcL:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 6et5 LIGHT-HARVESTING
PROTEIN B-1015 BETA
CHAIN
LIGHT-HARVESTING
PROTEIN B-1015 GAMMA
CHAIN
(Blastochloris
viridis) 		4 / 8 PRO 2  27
ILE 2  23
THR 1  32
ILE 1  35
 None
BCB  z 101 (-3.7A)
BCB  z 101 ( 3.7A)
None
 0.95A 5mzrE-6et52:
undetectable		 5mzrE-6et52:
16.44