SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BAU'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 ARG A 138
THR A 141
GLU A 248
MET A 249
GLU A 250
 PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.33A 1jdvA-3eufA:
24.5
1jdvD-3eufA:
24.4		 1jdvA-3eufA:
23.37
1jdvD-3eufA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 10 ARG A 144
THR A 147
GLU A 254
MET A 255
GLU A 256
 None
BAU  A 400 (-4.5A)
None
BAU  A 400 (-3.9A)
None
 0.35A 1jdvA-3p0fA:
24.0
1jdvD-3p0fA:
24.0		 1jdvA-3p0fA:
26.60
1jdvD-3p0fA:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 ARG A 138
THR A 141
GLU A 248
MET A 249
GLU A 250
 PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.32A 1jdvB-3eufA:
24.6
1jdvC-3eufA:
25.1		 1jdvB-3eufA:
23.37
1jdvC-3eufA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 10 ARG A 144
THR A 147
GLU A 254
MET A 255
GLU A 256
 None
BAU  A 400 (-4.5A)
None
BAU  A 400 (-3.9A)
None
 0.31A 1jdvB-3p0fA:
24.2
1jdvC-3p0fA:
24.6		 1jdvB-3p0fA:
26.60
1jdvC-3p0fA:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 ARG A 138
THR A 141
GLU A 248
MET A 249
GLU A 250
 PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.33A 1jdvA-3eufA:
24.5
1jdvD-3eufA:
24.4		 1jdvA-3eufA:
23.37
1jdvD-3eufA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 10 ARG A 144
THR A 147
GLU A 254
MET A 255
GLU A 256
 None
BAU  A 400 (-4.5A)
None
BAU  A 400 (-3.9A)
None
 0.35A 1jdvA-3p0fA:
24.0
1jdvD-3p0fA:
24.0		 1jdvA-3p0fA:
26.60
1jdvD-3p0fA:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 12 ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.32A 1jdvE-3eufA:
24.5
1jdvF-3eufA:
2.1		 1jdvE-3eufA:
23.37
1jdvF-3eufA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 12 ARG A 144
THR A 147
GLY A 149
GLU A 254
MET A 255
GLU A 256
 None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.30A 1jdvE-3p0fA:
24.1
1jdvF-3p0fA:
24.7		 1jdvE-3p0fA:
26.60
1jdvF-3p0fA:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.38A 1odiA-3eufA:
16.2		 1odiA-3eufA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 11 MET A 116
ARG A 144
THR A 147
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.44A 1odiA-3p0fA:
15.8		 1odiA-3p0fA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.37A 1odiB-3eufA:
24.8		 1odiB-3eufA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 11 MET A 116
ARG A 144
THR A 147
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.45A 1odiB-3p0fA:
24.4		 1odiB-3p0fA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.40A 1odiC-3eufA:
24.8		 1odiC-3eufA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 11 MET A 116
ARG A 144
THR A 147
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.47A 1odiC-3p0fA:
24.5		 1odiC-3p0fA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.35A 1odiD-3eufA:
24.7		 1odiD-3eufA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 11 MET A 116
ARG A 144
THR A 147
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.44A 1odiD-3p0fA:
24.3		 1odiD-3p0fA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.38A 1odiE-3eufA:
24.7		 1odiE-3eufA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 11 MET A 116
ARG A 144
THR A 147
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.44A 1odiE-3p0fA:
24.4		 1odiE-3p0fA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.37A 1odiF-3eufA:
24.6		 1odiF-3eufA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 11 MET A 116
ARG A 144
THR A 147
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.45A 1odiF-3p0fA:
24.3		 1odiF-3p0fA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 9 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.30A 1pk7A-3eufA:
24.9		 1pk7A-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 9 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.31A 1pk7A-3p0fA:
25.0		 1pk7A-3p0fA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.32A 1pk7B-3eufA:
25.3		 1pk7B-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.33A 1pk7B-3p0fA:
25.1		 1pk7B-3p0fA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 10 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.31A 1pk7C-3eufA:
25.4		 1pk7C-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 10 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.31A 1pk7C-3p0fA:
25.2		 1pk7C-3p0fA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 10 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.30A 1pk9A-3eufA:
25.0		 1pk9A-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 10 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.31A 1pk9A-3p0fA:
24.9		 1pk9A-3p0fA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 9 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.30A 1pk9B-3eufA:
25.2		 1pk9B-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 9 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.29A 1pk9B-3p0fA:
25.0		 1pk9B-3p0fA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.21A 1pk9C-3eufA:
24.3		 1pk9C-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 11 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.24A 1pk9C-3p0fA:
24.0		 1pk9C-3p0fA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 10 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.32A 1pw7A-3eufA:
25.1		 1pw7A-3eufA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 10 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.31A 1pw7A-3p0fA:
25.0		 1pw7A-3p0fA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 9 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.33A 1pw7B-3eufA:
25.2		 1pw7B-3eufA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 9 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.34A 1pw7B-3p0fA:
25.0		 1pw7B-3p0fA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.27A 1rxcB-3eufA:
26.8		 1rxcB-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.28A 1rxcB-3p0fA:
26.6		 1rxcB-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 7 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.40A 1rxcC-3eufA:
25.9		 1rxcC-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 7 GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.33A 1rxcC-3p0fA:
25.8		 1rxcC-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 7 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.28A 1rxcD-3eufA:
26.7		 1rxcD-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 7 GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.23A 1rxcD-3p0fA:
26.6		 1rxcD-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.31A 1rxcE-3eufA:
26.9		 1rxcE-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.29A 1rxcE-3p0fA:
26.7		 1rxcE-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 7 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.26A 1rxcF-3eufA:
27.0		 1rxcF-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 7 GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.19A 1rxcF-3p0fA:
26.8		 1rxcF-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.27A 1rxcI-3eufA:
27.0		 1rxcI-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.28A 1rxcI-3p0fA:
26.7		 1rxcI-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.32A 1rxcK-3eufA:
25.5		 1rxcK-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.28A 1rxcK-3p0fA:
25.4		 1rxcK-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 7 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.22A 1rxcL-3eufA:
27.0		 1rxcL-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 7 GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.18A 1rxcL-3p0fA:
26.7		 1rxcL-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.39A 1vhwA-3eufA:
25.0
1vhwD-3eufA:
25.1		 1vhwA-3eufA:
26.27
1vhwD-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 11 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.40A 1vhwA-3p0fA:
24.9
1vhwD-3p0fA:
25.1		 1vhwA-3p0fA:
24.29
1vhwD-3p0fA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 9 MET A 110
ARG A 138
GLY A 143
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.42A 1vhwB-3eufA:
24.9
1vhwF-3eufA:
24.6		 1vhwB-3eufA:
26.27
1vhwF-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 9 MET A 116
ARG A 144
GLY A 149
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
BAU  A 400 (-3.9A)
None
 0.43A 1vhwB-3p0fA:
24.8
1vhwF-3p0fA:
24.5		 1vhwB-3p0fA:
24.29
1vhwF-3p0fA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.40A 1vhwC-3eufA:
25.1
1vhwE-3eufA:
24.9		 1vhwC-3eufA:
26.27
1vhwE-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 11 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.40A 1vhwC-3p0fA:
25.0
1vhwE-3p0fA:
24.9		 1vhwC-3p0fA:
24.29
1vhwE-3p0fA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.40A 1vhwA-3eufA:
25.0
1vhwD-3eufA:
25.1		 1vhwA-3eufA:
26.27
1vhwD-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 11 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.40A 1vhwA-3p0fA:
24.9
1vhwD-3p0fA:
25.1		 1vhwA-3p0fA:
24.29
1vhwD-3p0fA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.39A 1vhwC-3eufA:
25.1
1vhwE-3eufA:
24.9		 1vhwC-3eufA:
26.27
1vhwE-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 11 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.40A 1vhwC-3p0fA:
25.0
1vhwE-3p0fA:
24.9		 1vhwC-3p0fA:
24.29
1vhwE-3p0fA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 10 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.41A 1vhwB-3eufA:
24.9
1vhwF-3eufA:
24.6		 1vhwB-3eufA:
26.27
1vhwF-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 10 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.41A 1vhwB-3p0fA:
24.8
1vhwF-3p0fA:
24.5		 1vhwB-3p0fA:
24.29
1vhwF-3p0fA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		8 / 10 MET A 110
ARG A 138
THR A 141
GLY A 143
THR A 210
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.58A 1z35A-3eufA:
23.8		 1z35A-3eufA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		8 / 10 MET A 116
ARG A 144
THR A 147
GLY A 149
THR A 216
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
None
BAU  A 400 (-3.9A)
None
 0.50A 1z35A-3p0fA:
23.7		 1z35A-3p0fA:
27.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 9 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.45A 1z37A-3eufA:
23.7		 1z37A-3eufA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 9 MET A 116
ARG A 144
THR A 147
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.40A 1z37A-3p0fA:
23.6		 1z37A-3p0fA:
27.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.38A 2ac7A-3eufA:
23.4
2ac7B-3eufA:
23.4		 2ac7A-3eufA:
24.33
2ac7B-3eufA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 11 MET A 116
ARG A 144
THR A 147
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.45A 2ac7A-3p0fA:
23.1
2ac7B-3p0fA:
23.1		 2ac7A-3p0fA:
27.73
2ac7B-3p0fA:
27.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.38A 2ac7A-3eufA:
23.4
2ac7B-3eufA:
23.4		 2ac7A-3eufA:
24.33
2ac7B-3eufA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 11 MET A 116
ARG A 144
THR A 147
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.45A 2ac7A-3p0fA:
23.1
2ac7B-3p0fA:
23.1		 2ac7A-3p0fA:
27.73
2ac7B-3p0fA:
27.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.74A 3kvrA-3eufA:
46.5		 3kvrA-3eufA:
75.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		9 / 10 THR A 141
GLY A 143
PHE A 213
GLN A 217
ARG A 219
GLU A 248
MET A 249
LEU A 272
LEU A 273
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-4.4A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
None
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
 0.26A 3kvrA-3eufA:
46.5		 3kvrA-3eufA:
75.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 10 THR A 147
GLY A 149
LEU A 278
LEU A 279
ILE A 287
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
BAU  A 400 (-4.6A)
 0.64A 3kvrA-3p0fA:
43.5		 3kvrA-3p0fA:
62.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		9 / 10 THR A 147
GLY A 149
PHE A 219
GLN A 223
ARG A 225
GLU A 254
MET A 255
LEU A 278
LEU A 279
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-4.4A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
None
BAU  A 400 (-3.9A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
 0.36A 3kvrA-3p0fA:
43.5		 3kvrA-3p0fA:
62.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.73A 3kvrB-3eufA:
46.7		 3kvrB-3eufA:
75.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		9 / 10 THR A 141
GLY A 143
PHE A 213
GLN A 217
ARG A 219
GLU A 248
MET A 249
LEU A 272
LEU A 273
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-4.4A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
None
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
 0.28A 3kvrB-3eufA:
46.7		 3kvrB-3eufA:
75.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 10 THR A 147
GLY A 149
LEU A 278
LEU A 279
ILE A 287
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
BAU  A 400 (-4.6A)
 0.67A 3kvrB-3p0fA:
10.1		 3kvrB-3p0fA:
62.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		9 / 10 THR A 147
GLY A 149
PHE A 219
GLN A 223
ARG A 225
GLU A 254
MET A 255
LEU A 278
LEU A 279
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-4.4A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
None
BAU  A 400 (-3.9A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
 0.38A 3kvrB-3p0fA:
10.1		 3kvrB-3p0fA:
62.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.23A 3kvvA-3eufA:
25.8		 3kvvA-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 6 GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.18A 3kvvA-3p0fA:
25.5		 3kvvA-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.24A 3kvvB-3eufA:
25.6		 3kvvB-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 6 GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.18A 3kvvB-3p0fA:
25.4		 3kvvB-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.24A 3kvvC-3eufA:
25.3		 3kvvC-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 6 GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.19A 3kvvC-3p0fA:
25.1		 3kvvC-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.31A 3kvvD-3eufA:
25.1		 3kvvD-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 6 GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.25A 3kvvD-3p0fA:
24.9		 3kvvD-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.27A 3kvvE-3eufA:
26.1		 3kvvE-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 6 GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.20A 3kvvE-3p0fA:
25.8		 3kvvE-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.28A 3kvvF-3eufA:
25.0		 3kvvF-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 6 GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.23A 3kvvF-3p0fA:
24.8		 3kvvF-3p0fA:
28.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		8 / 9 THR A 141
GLY A 143
GLN A 217
ARG A 219
GLU A 248
MET A 249
LEU A 272
LEU A 273
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
None
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
 0.25A 3nbqA-3eufA:
48.9		 3nbqA-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 9 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.73A 3nbqA-3eufA:
48.9		 3nbqA-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		8 / 9 THR A 147
GLY A 149
GLN A 223
ARG A 225
GLU A 254
MET A 255
LEU A 278
LEU A 279
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
None
BAU  A 400 (-3.9A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
 0.36A 3nbqA-3p0fA:
44.2		 3nbqA-3p0fA:
62.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 9 THR A 147
GLY A 149
LEU A 278
LEU A 279
ILE A 287
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
BAU  A 400 (-4.6A)
 0.63A 3nbqA-3p0fA:
44.2		 3nbqA-3p0fA:
62.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
LEU A 272
LEU A 273
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
 0.23A 3nbqB-3eufA:
48.7		 3nbqB-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.76A 3nbqB-3eufA:
48.7		 3nbqB-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 8 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
LEU A 278
LEU A 279
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
 0.34A 3nbqB-3p0fA:
44.1		 3nbqB-3p0fA:
62.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 THR A 147
GLY A 149
LEU A 278
LEU A 279
ILE A 287
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
BAU  A 400 (-4.6A)
 0.65A 3nbqB-3p0fA:
44.1		 3nbqB-3p0fA:
62.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
LEU A 272
LEU A 273
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
 0.26A 3nbqC-3eufA:
48.5		 3nbqC-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.75A 3nbqC-3eufA:
48.5		 3nbqC-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 8 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
LEU A 278
LEU A 279
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
 0.35A 3nbqC-3p0fA:
43.9		 3nbqC-3p0fA:
62.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 THR A 147
GLY A 149
LEU A 278
LEU A 279
ILE A 287
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
BAU  A 400 (-4.6A)
 0.64A 3nbqC-3p0fA:
43.9		 3nbqC-3p0fA:
62.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		8 / 9 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
LEU A 272
LEU A 273
ARG A 275
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
None
 0.28A 3nbqD-3eufA:
48.5		 3nbqD-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 9 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.84A 3nbqD-3eufA:
48.5		 3nbqD-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		8 / 9 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
LEU A 278
LEU A 279
ARG A 281
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
None
 0.37A 3nbqD-3p0fA:
44.1		 3nbqD-3p0fA:
62.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 9 THR A 147
GLY A 149
LEU A 278
LEU A 279
ILE A 287
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 ( 4.4A)
BAU  A 400 ( 4.5A)
BAU  A 400 (-4.6A)
 0.73A 3nbqD-3p0fA:
44.1		 3nbqD-3p0fA:
62.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 9 ASP A 279
GLY A 278
ILE A 281
GLY A 144
ILE A 145
 None
None
BAU  A 400 (-4.7A)
None
None
 0.93A 3ogpA-3eufA:
undetectable		 3ogpA-3eufA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 12 LEU A 196
GLY A 146
THR A 147
SER A 148
LEU A 304
 None
None
BAU  A 400 (-4.5A)
None
None
 1.31A 3okxA-3p0fA:
undetectable		 3okxA-3p0fA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 12 LEU A 196
GLY A 146
THR A 147
SER A 148
LEU A 304
 None
None
BAU  A 400 (-4.5A)
None
None
 1.30A 3okxB-3p0fA:
undetectable		 3okxB-3p0fA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 9 MET A 110
ARG A 138
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.43A 3u40A-3eufA:
23.9
3u40F-3eufA:
22.9		 3u40A-3eufA:
27.00
3u40F-3eufA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 9 MET A 116
ARG A 144
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
None
BAU  A 400 (-3.9A)
None
 0.40A 3u40A-3p0fA:
23.7
3u40F-3p0fA:
23.0		 3u40A-3p0fA:
24.00
3u40F-3p0fA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 MET A 110
ARG A 138
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.41A 3u40B-3eufA:
23.9
3u40C-3eufA:
23.5		 3u40B-3eufA:
27.00
3u40C-3eufA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 10 MET A 116
ARG A 144
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
None
BAU  A 400 (-3.9A)
None
 0.39A 3u40B-3p0fA:
23.9
3u40C-3p0fA:
23.4		 3u40B-3p0fA:
24.00
3u40C-3p0fA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 12 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.30A 3u40B-3eufA:
23.9
3u40C-3eufA:
23.5		 3u40B-3eufA:
27.00
3u40C-3eufA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 12 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.29A 3u40B-3p0fA:
23.9
3u40C-3p0fA:
23.4		 3u40B-3p0fA:
24.00
3u40C-3p0fA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.30A 3u40D-3eufA:
24.0
3u40E-3eufA:
23.3		 3u40D-3eufA:
27.00
3u40E-3eufA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 11 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.28A 3u40D-3p0fA:
23.8
3u40E-3p0fA:
23.1		 3u40D-3p0fA:
24.00
3u40E-3p0fA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 12 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.34A 3u40D-3eufA:
24.1
3u40E-3eufA:
23.3		 3u40D-3eufA:
27.00
3u40E-3eufA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 12 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.35A 3u40D-3p0fA:
23.8
3u40E-3p0fA:
23.1		 3u40D-3p0fA:
24.00
3u40E-3p0fA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 MET A 110
ARG A 138
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.36A 3u40A-3eufA:
23.8
3u40F-3eufA:
22.9		 3u40A-3eufA:
27.00
3u40F-3eufA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 10 MET A 116
ARG A 144
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
None
BAU  A 400 (-3.9A)
None
 0.35A 3u40A-3p0fA:
23.7
3u40F-3p0fA:
22.9		 3u40A-3p0fA:
24.00
3u40F-3p0fA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.40A 3uawA-3eufA:
24.1		 3uawA-3eufA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 11 MET A 116
ARG A 144
THR A 147
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.48A 3uawA-3p0fA:
23.8		 3uawA-3p0fA:
27.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 10 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.38A 3uayA-3eufA:
24.6		 3uayA-3eufA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		7 / 10 MET A 116
ARG A 144
THR A 147
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.43A 3uayA-3p0fA:
24.3		 3uayA-3p0fA:
26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.34A 4d9hA-3eufA:
25.0		 4d9hA-3eufA:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 11 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.38A 4d9hA-3p0fA:
24.7		 4d9hA-3p0fA:
26.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 10 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.38A 4da7A-3eufA:
24.9		 4da7A-3eufA:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 10 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.42A 4da7A-3p0fA:
24.6		 4da7A-3p0fA:
26.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.32A 4danA-3eufA:
24.5		 4danA-3eufA:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		6 / 11 MET A 116
ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.37A 4danA-3p0fA:
24.2		 4danA-3p0fA:
26.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 12 ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.42A 4danA-3eufA:
24.5
4danB-3eufA:
24.4		 4danA-3eufA:
27.05
4danB-3eufA:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 12 ARG A 144
GLY A 149
GLU A 254
MET A 255
GLU A 256
 None
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.43A 4danA-3p0fA:
24.2
4danB-3p0fA:
24.1		 4danA-3p0fA:
26.38
4danB-3p0fA:
26.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.28A 4e1vA-3eufA:
25.8		 4e1vA-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.24A 4e1vA-3p0fA:
25.8		 4e1vA-3p0fA:
29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 7 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.33A 4e1vB-3eufA:
25.5		 4e1vB-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 7 GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.28A 4e1vB-3p0fA:
25.5		 4e1vB-3p0fA:
29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.31A 4e1vC-3eufA:
25.3		 4e1vC-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.28A 4e1vC-3p0fA:
25.3		 4e1vC-3p0fA:
29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.32A 4e1vD-3eufA:
25.5		 4e1vD-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.29A 4e1vD-3p0fA:
25.5		 4e1vD-3p0fA:
29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.32A 4e1vE-3eufA:
26.0		 4e1vE-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.28A 4e1vE-3p0fA:
26.0		 4e1vE-3p0fA:
29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.30A 4e1vF-3eufA:
25.5		 4e1vF-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 6 GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.25A 4e1vF-3p0fA:
25.4		 4e1vF-3p0fA:
29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.50A 4e1vG-3eufA:
25.1		 4e1vG-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.47A 4e1vG-3p0fA:
25.0		 4e1vG-3p0fA:
29.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.31A 4e1vH-3eufA:
25.7		 4e1vH-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 8 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.26A 4e1vH-3p0fA:
25.6		 4e1vH-3p0fA:
29.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 7 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.25A 4txnA-3eufA:
41.4		 4txnA-3eufA:
40.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 7 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.28A 4txnA-3p0fA:
39.5		 4txnA-3p0fA:
42.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 7 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.26A 4txnB-3eufA:
41.6		 4txnB-3eufA:
40.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 7 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.28A 4txnB-3p0fA:
39.7		 4txnB-3p0fA:
42.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 7 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.25A 4txnC-3eufA:
41.6		 4txnC-3eufA:
40.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 7 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.31A 4txnC-3p0fA:
39.5		 4txnC-3p0fA:
42.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 7 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.25A 4txnD-3eufA:
41.6		 4txnD-3eufA:
40.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 7 THR A 147
GLY A 149
GLN A 223
ARG A 225
MET A 255
 BAU  A 400 (-4.5A)
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
 0.31A 4txnD-3p0fA:
39.5		 4txnD-3p0fA:
42.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 9 MET A 110
ARG A 138
GLY A 143
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.40A 5i3cA-3eufA:
24.8		 5i3cA-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 9 MET A 116
ARG A 144
GLY A 149
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
None
BAU  A 400 (-3.5A)
BAU  A 400 (-3.9A)
None
 0.40A 5i3cA-3p0fA:
24.7		 5i3cA-3p0fA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 MET A 110
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.32A 5i3cB-3eufA:
25.1		 5i3cB-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 10 MET A 116
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.37A 5i3cB-3p0fA:
14.8		 5i3cB-3p0fA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 11 MET A 110
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.31A 5i3cC-3eufA:
24.9		 5i3cC-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		5 / 11 MET A 116
GLY A 149
GLU A 254
MET A 255
GLU A 256
 BAU  A 400 (-3.4A)
BAU  A 400 (-3.5A)
None
BAU  A 400 (-3.9A)
None
 0.34A 5i3cC-3p0fA:
24.8		 5i3cC-3p0fA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 8 GLY A 149
ILE A 151
ASP A 280
ASP A 285
 BAU  A 400 (-3.5A)
None
MG  A 315 (-3.2A)
None
 0.89A 5vlmH-3p0fA:
undetectable		 5vlmH-3p0fA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 5 THR A 141
THR A 210
GLN A 217
ASP A 160
 PO4  A 401 ( 3.0A)
None
BAU  A 400 (-3.1A)
None
 1.32A 6ectA-3eufA:
undetectable		 6ectA-3eufA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 5 THR A 271
THR A 210
GLN A 217
ASP A 160
 None
None
BAU  A 400 (-3.1A)
None
 1.45A 6ectA-3eufA:
undetectable		 6ectA-3eufA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 5 THR A 147
THR A 216
GLN A 223
ASP A 166
 BAU  A 400 (-4.5A)
None
BAU  A 400 (-3.1A)
None
 1.38A 6ectA-3p0fA:
undetectable		 6ectA-3p0fA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 5 THR A 277
THR A 216
GLN A 223
ASP A 166
 None
None
BAU  A 400 (-3.1A)
None
 1.46A 6ectA-3p0fA:
undetectable		 6ectA-3p0fA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 5 THR A 271
THR A 210
GLN A 217
ASP A 160
 None
None
BAU  A 400 (-3.1A)
None
 1.43A 6ecxA-3eufA:
undetectable		 6ecxA-3eufA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 3p0f URIDINE
PHOSPHORYLASE 2
(Homo
sapiens) 		4 / 5 THR A 277
THR A 216
GLN A 223
ASP A 166
 None
None
BAU  A 400 (-3.1A)
None
 1.43A 6ecxA-3p0fA:
undetectable		 6ecxA-3p0fA:
21.83