SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'B7N'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 4j7q PHOSPHATIDYLINOSITOL
TRANSFER PROTEIN
PDR16
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 237
LEU A 195
ILE A 199
PRO A 162
GLN A 145
 B7N  A 401 (-3.9A)
B7N  A 401 ( 4.9A)
None
None
None
 1.27A 2ft9A-4j7qA:
undetectable		 2ft9A-4j7qA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 4j7q PHOSPHATIDYLINOSITOL
TRANSFER PROTEIN
PDR16
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 136
LEU A 160
HIS A 176
LEU A 177
ARG A 164
 None
None
None
B7N  A 401 (-4.3A)
None
 1.19A 5hnwB-4j7qA:
undetectable		 5hnwB-4j7qA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4j7q PHOSPHATIDYLINOSITOL
TRANSFER PROTEIN
PDR16
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 136
LEU A 160
HIS A 176
LEU A 177
ARG A 164
 None
None
None
B7N  A 401 (-4.3A)
None
 1.15A 5hnyB-4j7qA:
undetectable		 5hnyB-4j7qA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4j7q PHOSPHATIDYLINOSITOL
TRANSFER PROTEIN
PDR16
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 136
LEU A 160
HIS A 176
LEU A 177
ARG A 164
 None
None
None
B7N  A 401 (-4.3A)
None
 1.21A 5nd7B-4j7qA:
undetectable		 5nd7B-4j7qA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4j7q PHOSPHATIDYLINOSITOL
TRANSFER PROTEIN
PDR16
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 184
LEU A 158
LEU A 197
LEU A 177
 None
None
B7N  A 401 (-4.6A)
B7N  A 401 (-4.3A)
 1.07A 6f6sA-4j7qA:
undetectable
6f6sB-4j7qA:
undetectable		 6f6sA-4j7qA:
13.74
6f6sB-4j7qA:
13.33