SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'B7M'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		4 / 8 LEU A  30
ALA A  51
ILE A  52
GLY A  13
 None
None
B7M  A1145 ( 4.6A)
None
 0.76A 1sv9A-2wchA:
undetectable		 1sv9A-2wchA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		5 / 12 MET A   5
LEU A  16
LEU A  61
MET A  90
ILE A  94
 None
None
B7M  A1145 ( 4.7A)
None
B7M  A1145 ( 4.5A)
 1.01A 2jfaA-2wchA:
undetectable		 2jfaA-2wchA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		5 / 12 MET A   5
THR A   9
LEU A  16
LEU A  61
MET A  90
 None
B7M  A1145 ( 4.1A)
None
B7M  A1145 ( 4.7A)
None
 1.01A 2jfaA-2wchA:
undetectable		 2jfaA-2wchA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		5 / 12 MET A   5
THR A   9
LEU A  16
LEU A  61
ILE A  94
 None
B7M  A1145 ( 4.1A)
None
B7M  A1145 ( 4.7A)
B7M  A1145 ( 4.5A)
 0.86A 2ouzA-2wchA:
undetectable		 2ouzA-2wchA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		5 / 6 ARG A  20
LEU A  16
PHE A  12
PHE A  33
LEU A  30
 None
None
B7M  A1145 (-3.7A)
None
None
 1.42A 3abkP-2wchA:
undetectable
3abkW-2wchA:
undetectable		 3abkP-2wchA:
17.25
3abkW-2wchA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		5 / 8 ARG A  20
LEU A  16
PHE A  12
PHE A  33
LEU A  30
 None
None
B7M  A1145 (-3.7A)
None
None
 1.38A 3asoC-2wchA:
undetectable
3asoJ-2wchA:
undetectable		 3asoC-2wchA:
17.25
3asoJ-2wchA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		4 / 5 PHE A  80
ILE A 127
MET A  73
ASN A  72
 None
None
B7M  A1145 (-4.4A)
None
 1.39A 3octA-2wchA:
undetectable		 3octA-2wchA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		3 / 3 PHE A  36
ASP A  39
ARG A 123
 B7M  A1145 ( 4.0A)
None
None
 0.87A 4eahF-2wchA:
undetectable		 4eahF-2wchA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		3 / 3 PHE A  36
ASP A  39
ARG A 123
 B7M  A1145 ( 4.0A)
None
None
 0.87A 4eahG-2wchA:
undetectable		 4eahG-2wchA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		5 / 12 MET A   5
THR A   9
LEU A  61
MET A  90
ILE A  94
 None
B7M  A1145 ( 4.1A)
B7M  A1145 ( 4.7A)
None
B7M  A1145 ( 4.5A)
 0.92A 5gs4A-2wchA:
undetectable		 5gs4A-2wchA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		4 / 5 ARG A  20
LEU A  16
PHE A  12
LEU A  30
 None
None
B7M  A1145 (-3.7A)
None
 1.22A 5iy5P-2wchA:
undetectable
5iy5W-2wchA:
undetectable		 5iy5P-2wchA:
17.93
5iy5W-2wchA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		4 / 5 ARG A  20
LEU A  16
PHE A  12
LEU A  30
 None
None
B7M  A1145 (-3.7A)
None
 1.22A 5xdxC-2wchA:
undetectable
5xdxJ-2wchA:
undetectable		 5xdxC-2wchA:
17.72
5xdxJ-2wchA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2wch GENERAL
ODORANT-BINDING
PROTEIN 1
(Bombyx
mori) 		4 / 5 ARG A  20
LEU A  16
PHE A  12
LEU A  30
 None
None
B7M  A1145 (-3.7A)
None
 1.22A 5xdxP-2wchA:
undetectable
5xdxW-2wchA:
undetectable		 5xdxP-2wchA:
17.72
5xdxW-2wchA:
16.92