SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'B6G'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 5wmm NRPS
(Micromonospora
sp.
ML1) 		3 / 3 THR A 313
PRO A 308
THR A 309
 None
B6G  A1001 (-4.5A)
B6G  A1001 (-3.8A)
 0.85A 1ovfB-5wmmA:
undetectable		 1ovfB-5wmmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5wmm NRPS
(Micromonospora
sp.
ML1) 		4 / 7 GLY A 282
GLY A 307
THR A 309
ARG A 424
 B6G  A1001 (-3.4A)
B6G  A1001 (-4.8A)
B6G  A1001 (-3.8A)
B6G  A1001 (-4.0A)
 0.34A 2wd9A-5wmmA:
39.0		 2wd9A-5wmmA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5wmm NRPS
(Micromonospora
sp.
ML1) 		4 / 8 GLY A 282
GLY A 307
THR A 309
ARG A 424
 B6G  A1001 (-3.4A)
B6G  A1001 (-4.8A)
B6G  A1001 (-3.8A)
B6G  A1001 (-4.0A)
 0.31A 2wd9B-5wmmA:
40.6		 2wd9B-5wmmA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5wmm NRPS
(Micromonospora
sp.
ML1) 		5 / 10 THR A 170
GLY A 282
GLY A 307
THR A 309
ARG A 424
 None
B6G  A1001 (-3.4A)
B6G  A1001 (-4.8A)
B6G  A1001 (-3.8A)
B6G  A1001 (-4.0A)
 0.37A 2wd9C-5wmmA:
40.2		 2wd9C-5wmmA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 5wmm NRPS
(Micromonospora
sp.
ML1) 		5 / 7 ASP A 213
GLY A 282
THR A 309
PHE A 314
LYS A 419
 B6G  A1001 (-2.7A)
B6G  A1001 (-3.4A)
B6G  A1001 (-3.8A)
B6G  A1001 ( 4.7A)
B6G  A1001 (-3.0A)
 1.03A 3vnsA-5wmmA:
47.2		 3vnsA-5wmmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 5wmm NRPS
(Micromonospora
sp.
ML1) 		5 / 7 PHE A 212
ASP A 213
GLY A 282
THR A 309
PHE A 314
 CA  A1008 (-4.2A)
B6G  A1001 (-2.7A)
B6G  A1001 (-3.4A)
B6G  A1001 (-3.8A)
B6G  A1001 ( 4.7A)
 0.52A 3vnsA-5wmmA:
47.2		 3vnsA-5wmmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 5wmm NRPS
(Micromonospora
sp.
ML1) 		4 / 7 PHE A 212
ASP A 213
GLY A 282
THR A 309
 CA  A1008 (-4.2A)
B6G  A1001 (-2.7A)
B6G  A1001 (-3.4A)
B6G  A1001 (-3.8A)
 0.36A 4zxiA-5wmmA:
44.0		 4zxiA-5wmmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 5wmm NRPS
(Micromonospora
sp.
ML1) 		4 / 7 PHE A 212
ASP A 213
GLY A 282
GLY A 307
 CA  A1008 (-4.2A)
B6G  A1001 (-2.7A)
B6G  A1001 (-3.4A)
B6G  A1001 (-4.8A)
 0.56A 5n9xA-5wmmA:
47.8		 5n9xA-5wmmA:
undetectable