SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'B4P'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
11 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
CYH A 122
ALA A 135
LEU A 137
PHE A 168
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
None
B4P  A 349 (-3.4A)
B4P  A 349 (-3.4A)
0.28A 1bx4A-3looA:
51.0
1bx4A-3looA:
48.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 THR A 263
GLY A 265
VAL A 284
ALA A 298
GLY A 299
ALA A 327
ILE A 331
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.3A)
B4P  A 349 (-3.3A)
B4P  A 349 (-3.4A)
None
0.56A 1bx4A-3looA:
51.0
1bx4A-3looA:
48.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DGM_A_ADNA375_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
5 / 9 ASN A  14
ASP A  18
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.56A 1dgmA-3looA:
35.5
1dgmA-3looA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DGM_A_ADNA375_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
5 / 9 ASP A  18
GLY A  64
ASN A  68
CYH A 122
LEU A 133
B4P  A 349 (-2.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-4.5A)
0.51A 1dgmA-3looA:
35.5
1dgmA-3looA:
33.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LII_A_ADNA699_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
10 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
CYH A 122
LEU A 137
ASN A 296
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.54A 1liiA-3looA:
45.3
1liiA-3looA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
9 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
CYH A 122
ASN A 296
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.76A 1likA-3looA:
44.6
1likA-3looA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 10 THR A 263
GLY A 265
VAL A 269
VAL A 284
ALA A 298
ALA A 327
ILE A 331
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-4.7A)
None
B4P  A 349 (-3.3A)
B4P  A 349 (-3.4A)
None
0.47A 1likA-3looA:
44.6
1likA-3looA:
34.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
5 / 12 ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.28A 2c49A-3looA:
28.4
2c49A-3looA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
4 / 7 ASP A  18
GLY A  63
GLY A  64
ASN A  68
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
0.45A 2c49B-3looA:
27.0
2c49B-3looA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
5 / 12 PHE A 169
ASN A  14
PHE A 191
PHE A 170
GLY A 167
None
B4P  A 349 ( 4.0A)
None
None
None
1.32A 2fqyA-3looA:
3.0
2fqyA-3looA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASP A  18
GLY A  63
GLY A  64
ASN A  68
GLY A 297
ASP A 300
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.26A 2pkkA-3looA:
28.6
2pkkA-3looA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASP A  18
GLY A  63
GLY A  64
ASN A  68
GLY A 297
ASP A 300
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.25A 2pkmA-3looA:
28.4
2pkmA-3looA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
SER A  65
ASN A  68
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
CL  A 351 ( 4.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.30A 3uboA-3looA:
38.9
3uboA-3looA:
29.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.49A 3uboB-3looA:
39.5
3uboB-3looA:
29.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
5 / 12 ASP A  18
GLY A  64
ASN A  68
LEU A  40
ASP A 300
B4P  A 349 (-2.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
1.01A 3uboB-3looA:
39.5
3uboB-3looA:
29.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
9 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
LEU A 137
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.27A 3uq6A-3looA:
47.7
3uq6A-3looA:
38.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
8 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  64
ASN A  68
LEU A 137
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.38A 3uq6B-3looA:
46.6
3uq6B-3looA:
38.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
4 / 5 LEU A  16
GLY A  63
PHE A 168
ASN A 296
B4P  A 349 (-4.7A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.6A)
0.59A 3uq6B-3looA:
46.6
3uq6B-3looA:
38.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
9 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
LEU A 137
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.36A 3vaqA-3looA:
47.4
3vaqA-3looA:
38.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
8 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  64
ASN A  68
LEU A 137
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.44A 3vaqB-3looA:
47.1
3vaqB-3looA:
38.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
9 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
LEU A 137
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.32A 3vasA-3looA:
47.5
3vasA-3looA:
38.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
9 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
LEU A 137
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.39A 3vasB-3looA:
47.0
3vasB-3looA:
38.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
8 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
ASN A  68
LEU A 137
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.55A 4dc3A-3looA:
46.4
4dc3A-3looA:
38.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
LEU A  40
ASN A  68
LEU A 137
GLY A 299
ASP A 300
B4P  A 349 ( 4.0A)
None
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.3A)
B4P  A 349 (-3.4A)
1.37A 4dc3A-3looA:
46.4
4dc3A-3looA:
38.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
10 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASN A 296
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.6A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.71A 4dc3B-3looA:
47.5
4dc3B-3looA:
38.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.38A 4e3aA-3looA:
39.4
4e3aA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
8 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.38A 4e3aB-3looA:
39.6
4e3aB-3looA:
30.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
3 / 3 PHE A 168
VAL A 215
ILE A 211
B4P  A 349 (-3.4A)
None
None
0.54A 4emaA-3looA:
undetectable
4emaA-3looA:
23.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.26A 4jksA-3looA:
39.6
4jksA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.27A 4jksB-3looA:
39.5
4jksB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.27A 4jkuA-3looA:
39.5
4jkuA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.43A 4jkuB-3looA:
39.4
4jkuB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K8C_A_ADNA401_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.28A 4k8cA-3looA:
39.4
4k8cA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K8C_B_ADNB401_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.28A 4k8cB-3looA:
39.5
4k8cB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K8K_A_ADNA401_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.27A 4k8kA-3looA:
39.4
4k8kA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K8K_B_ADNB403_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.27A 4k8kB-3looA:
39.4
4k8kB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K8P_A_ADNA401_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.42A 4k8pA-3looA:
39.5
4k8pA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K8P_B_ADNB401_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.41A 4k8pB-3looA:
39.5
4k8pB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K8T_A_ADNA401_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.40A 4k8tA-3looA:
39.4
4k8tA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K8T_B_ADNB401_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.40A 4k8tB-3looA:
39.5
4k8tB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K93_A_ADNA401_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.39A 4k93A-3looA:
39.5
4k93A-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K93_B_ADNB402_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.38A 4k93B-3looA:
39.4
4k93B-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K9C_A_ADNA401_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.42A 4k9cA-3looA:
39.6
4k9cA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K9C_B_ADNB401_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.41A 4k9cB-3looA:
39.6
4k9cB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K9I_A_ADNA401_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.38A 4k9iA-3looA:
39.6
4k9iA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K9I_B_ADNB401_1
(SUGAR KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.40A 4k9iB-3looA:
39.5
4k9iB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.41A 4kadA-3looA:
39.5
4kadA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.42A 4kadB-3looA:
39.5
4kadB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.25A 4kahA-3looA:
39.6
4kahA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.26A 4kahB-3looA:
39.4
4kahB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.27A 4kalA-3looA:
39.4
4kalA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.27A 4kalB-3looA:
39.5
4kalB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.27A 4kanA-3looA:
39.6
4kanA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.28A 4kanB-3looA:
39.5
4kanB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.25A 4kbeA-3looA:
39.6
4kbeA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.26A 4kbeB-3looA:
39.5
4kbeB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.27A 4lbgA-3looA:
39.5
4lbgA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.27A 4lbgB-3looA:
39.5
4lbgB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.40A 4lbxA-3looA:
39.6
4lbxA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.41A 4lbxB-3looA:
39.6
4lbxB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.42A 4lc4A-3looA:
39.4
4lc4A-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
LEU A 137
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
0.41A 4lc4B-3looA:
39.6
4lc4B-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.27A 4lcaA-3looA:
39.5
4lcaA-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 ASN A  14
ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.27A 4lcaB-3looA:
39.5
4lcaB-3looA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_A_ADNA401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
10 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  64
ASN A  68
CYH A 122
ALA A 135
PHE A 168
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.4A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.46A 4n09A-3looA:
48.1
4n09A-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_A_ADNA401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
10 / 12 ASN A  14
LEU A  40
GLY A  64
ASN A  68
CYH A 122
ALA A 135
PHE A 168
ASN A 296
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
None
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.6A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.78A 4n09A-3looA:
48.1
4n09A-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_A_ADNA401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 GLY A  63
ASN A  68
CYH A 122
ALA A 135
GLY A 297
ASP A 300
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
1.17A 4n09A-3looA:
48.1
4n09A-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_A_ADNA401_2
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
4 / 4 LEU A  16
SER A  65
LEU A 133
LEU A 137
B4P  A 349 (-4.7A)
CL  A 351 ( 4.6A)
B4P  A 349 (-4.5A)
None
0.44A 4n09A-3looA:
48.1
4n09A-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_B_ADNB401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
11 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
CYH A 122
ALA A 135
PHE A 168
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.4A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.54A 4n09B-3looA:
48.0
4n09B-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_B_ADNB401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
LEU A  40
GLY A  64
ASN A  68
PHE A 168
GLY A 299
ASP A 300
B4P  A 349 ( 4.0A)
None
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.3A)
B4P  A 349 (-3.4A)
1.14A 4n09B-3looA:
48.0
4n09B-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_B_ADNB401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 GLY A  63
ASN A  68
CYH A 122
ALA A 135
GLY A 297
ASP A 300
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
1.21A 4n09B-3looA:
48.0
4n09B-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_B_ADNB401_2
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
4 / 5 LEU A  16
SER A  65
LEU A 133
LEU A 137
B4P  A 349 (-4.7A)
CL  A 351 ( 4.6A)
B4P  A 349 (-4.5A)
None
0.45A 4n09B-3looA:
48.0
4n09B-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_C_ADNC401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
11 / 12 ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
CYH A 122
ALA A 135
LEU A 137
PHE A 168
GLY A 297
ASP A 300
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
None
B4P  A 349 (-3.4A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.52A 4n09C-3looA:
48.0
4n09C-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_C_ADNC401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 GLY A  63
ASN A  68
CYH A 122
ALA A 135
GLY A 297
ASP A 300
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
1.20A 4n09C-3looA:
48.0
4n09C-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_C_ADNC401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 LEU A  40
GLY A  64
ASN A  68
LEU A 137
PHE A 168
GLY A 299
ASP A 300
None
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.4A)
B4P  A 349 (-3.3A)
B4P  A 349 (-3.4A)
1.16A 4n09C-3looA:
48.0
4n09C-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_C_ADNC401_2
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
4 / 5 ASN A  14
LEU A  16
SER A  65
ASN A 296
B4P  A 349 ( 4.0A)
B4P  A 349 (-4.7A)
CL  A 351 ( 4.6A)
B4P  A 349 (-3.6A)
0.88A 4n09C-3looA:
48.0
4n09C-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_C_ADNC401_2
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
4 / 5 ASN A  14
LEU A  16
SER A  65
LEU A 133
B4P  A 349 ( 4.0A)
B4P  A 349 (-4.7A)
CL  A 351 ( 4.6A)
B4P  A 349 (-4.5A)
0.50A 4n09C-3looA:
48.0
4n09C-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_D_ADND401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
11 / 12 ASN A  14
ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
CYH A 122
ALA A 135
PHE A 168
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.4A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.55A 4n09D-3looA:
47.9
4n09D-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_D_ADND401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
10 / 12 ASN A  14
LEU A  40
GLY A  64
ASN A  68
CYH A 122
ALA A 135
PHE A 168
ASN A 296
GLY A 297
ASP A 300
B4P  A 349 ( 4.0A)
None
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.6A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.91A 4n09D-3looA:
47.9
4n09D-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_D_ADND401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 ASN A  14
LEU A  40
GLY A  64
ASN A  68
PHE A 168
GLY A 299
ASP A 300
B4P  A 349 ( 4.0A)
None
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.3A)
B4P  A 349 (-3.4A)
1.12A 4n09D-3looA:
47.9
4n09D-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_D_ADND401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 GLY A  63
ASN A  68
CYH A 122
ALA A 135
GLY A 297
ASP A 300
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
1.22A 4n09D-3looA:
47.9
4n09D-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N09_D_ADND401_2
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
4 / 5 LEU A  16
SER A  65
LEU A 133
LEU A 137
B4P  A 349 (-4.7A)
CL  A 351 ( 4.6A)
B4P  A 349 (-4.5A)
None
0.47A 4n09D-3looA:
47.9
4n09D-3looA:
36.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
5 / 12 ASP A  18
GLY A  63
GLY A  64
ASN A  68
ASP A 300
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
0.29A 4ubeA-3looA:
28.5
4ubeA-3looA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)
3a74 LYSYL-TRNA
SYNTHETASE

(Geobacillus
stearothermophil
us)
5 / 12 ASN A 414
ALA A 209
GLU A 418
GLU A 231
LEU A 232
B4P  A 494 (-3.8A)
None
LYN  A 495 (-2.9A)
LYN  A 495 (-3.0A)
None
1.35A 4zjoA-3a74A:
1.7
4zjoA-3a74A:
18.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
11 / 12 ASP A  18
GLY A  63
GLY A  64
ASN A  68
CYH A 122
ALA A 135
LEU A 137
PHE A 168
ASN A 296
GLY A 297
ASP A 300
B4P  A 349 (-2.8A)
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
None
B4P  A 349 (-3.4A)
B4P  A 349 (-3.6A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.53A 5kb5A-3looA:
51.7
5kb5A-3looA:
51.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
11 / 12 ASP A  18
LEU A  40
GLY A  63
GLY A  64
ASN A  68
CYH A 122
ALA A 135
LEU A 137
PHE A 168
GLY A 297
ASP A 300
B4P  A 349 (-2.8A)
None
B4P  A 349 ( 3.8A)
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
None
B4P  A 349 (-3.4A)
B4P  A 349 (-2.9A)
B4P  A 349 (-3.4A)
0.25A 5kb5A-3looA:
51.7
5kb5A-3looA:
51.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
6 / 12 GLY A  64
ASN A  68
CYH A 122
ALA A 135
ASN A 296
GLY A 297
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.6A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.6A)
B4P  A 349 (-2.9A)
1.15A 5kb5A-3looA:
51.7
5kb5A-3looA:
51.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
4 / 4 ASN A  14
LEU A  16
SER A  65
LEU A 133
B4P  A 349 ( 4.0A)
B4P  A 349 (-4.7A)
CL  A 351 ( 4.6A)
B4P  A 349 (-4.5A)
0.45A 5kb5A-3looA:
51.7
5kb5A-3looA:
51.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 THR A 263
GLY A 265
VAL A 284
ALA A 298
GLY A 299
ALA A 327
ILE A 331
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.3A)
B4P  A 349 (-3.3A)
B4P  A 349 (-3.4A)
None
0.48A 5kb6A-3looA:
46.2
5kb6A-3looA:
48.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
7 / 12 THR A 263
GLY A 265
VAL A 284
ALA A 298
GLY A 299
ALA A 327
ILE A 331
B4P  A 349 (-3.5A)
B4P  A 349 (-3.6A)
None
B4P  A 349 (-3.3A)
B4P  A 349 (-3.3A)
B4P  A 349 (-3.4A)
None
0.45A 5kb6B-3looA:
46.4
5kb6B-3looA:
48.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
4 / 5 ASN A 194
ASP A 300
ASN A  68
ASP A  18
MG  A 350 ( 4.7A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.6A)
B4P  A 349 (-2.8A)
1.12A 5vooA-3looA:
undetectable
5vooA-3looA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
4 / 5 ASN A 194
ASP A 300
ASN A  68
ASP A  18
MG  A 350 ( 4.7A)
B4P  A 349 (-3.4A)
B4P  A 349 (-3.6A)
B4P  A 349 (-2.8A)
1.13A 5vooC-3looA:
undetectable
5vooC-3looA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
5 / 12 ILE A 261
PHE A 168
VAL A  72
ALA A  73
LEU A 307
None
B4P  A 349 (-3.4A)
None
None
None
1.00A 6ajiA-3looA:
undetectable
6ajiA-3looA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
5 / 9 ASP A 300
ALA A 102
GLY A  13
PHE A  85
SER A  69
B4P  A 349 (-3.4A)
None
CL  A 351 ( 3.7A)
None
None
1.32A 6awoA-3looA:
undetectable
6awoA-3looA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae)
5 / 9 ASP A 300
ALA A 102
GLY A  13
PHE A  85
SER A  69
B4P  A 349 (-3.4A)
None
CL  A 351 ( 3.7A)
None
None
1.33A 6awqA-3looA:
undetectable
6awqA-3looA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)
3a74 LYSYL-TRNA
SYNTHETASE

(Geobacillus
stearothermophil
us)
7 / 10 ARG A 253
GLU A 255
HIS A 261
PHE A 265
GLY A 467
ARG A 470
ILE A 481
B4P  A 494 ( 2.7A)
B4P  A 494 (-3.7A)
B4P  A 494 (-3.5A)
B4P  A 494 (-3.4A)
B4P  A 494 (-3.2A)
B4P  A 494 (-2.8A)
None
0.32A 6bniA-3a74A:
44.7
6bniA-3a74A:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)
3a74 LYSYL-TRNA
SYNTHETASE

(Geobacillus
stearothermophil
us)
5 / 10 GLU A 255
HIS A 261
GLU A 411
ARG A 470
ILE A 481
B4P  A 494 (-3.7A)
B4P  A 494 (-3.5A)
B4P  A 494 (-3.4A)
B4P  A 494 (-2.8A)
None
1.16A 6bniA-3a74A:
44.7
6bniA-3a74A:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)
3a74 LYSYL-TRNA
SYNTHETASE

(Geobacillus
stearothermophil
us)
7 / 10 ARG A 253
GLU A 255
HIS A 261
PHE A 265
GLY A 467
ARG A 470
ILE A 481
B4P  A 494 ( 2.7A)
B4P  A 494 (-3.7A)
B4P  A 494 (-3.5A)
B4P  A 494 (-3.4A)
B4P  A 494 (-3.2A)
B4P  A 494 (-2.8A)
None
0.35A 6bniB-3a74A:
44.4
6bniB-3a74A:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)
3a74 LYSYL-TRNA
SYNTHETASE

(Geobacillus
stearothermophil
us)
5 / 10 GLU A 255
HIS A 261
GLU A 411
ARG A 470
ILE A 481
B4P  A 494 (-3.7A)
B4P  A 494 (-3.5A)
B4P  A 494 (-3.4A)
B4P  A 494 (-2.8A)
None
1.17A 6bniB-3a74A:
44.4
6bniB-3a74A:
9.07