SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'B2M'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQF_A_SAMA430_0 (SUN PROTEIN)	3dho	STREPTOGRAMIN A ACETYLTRANSFERASE (Enterococcus faecium)	5 / 12	ALA A 156 GLY A 157 GLY A 158 ASP A 136 GLY A 117	None B2M A 302 (-3.5A) B2M A 302 (-4.0A) None None	0.99A	1sqfA-3dhoA: undetectable	1sqfA-3dhoA: 18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DT8_A_ADNA401_1 (APH(2'')-ID)	3dho	STREPTOGRAMIN A ACETYLTRANSFERASE (Enterococcus faecium)	5 / 11	GLY A 157 ALA A 156 ILE A 150 ILE A 116 ILE A 122	B2M A 302 (-3.5A) None None None None	1.10A	4dt8A-3dhoA: undetectable	4dt8A-3dhoA: 22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J5J_B_478B401_2 (PROTEASE)	3dho	STREPTOGRAMIN A ACETYLTRANSFERASE (Enterococcus faecium)	5 / 10	ILE A 134 VAL A 146 GLY A 157 ILE A 164 VAL A 120	None None B2M A 302 (-3.5A) B2M A 302 ( 4.0A) None	1.08A	4j5jB-3dhoA: undetectable	4j5jB-3dhoA: 21.72