SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'B1M'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AEG_A_4APA296_1 (CYTOCHROME C PEROXIDASE)	1y80	PREDICTED COBALAMIN BINDING PROTEIN (Moorella thermoacetica)	4 / 8	HIS A 101 GLY A 178 LEU A 149 ASP A 99	B1M A 301 (-3.6A) B1M A 301 (-3.2A) B1M A 301 (-4.3A) B1M A 301 (-4.2A)	0.85A	1aegA-1y80A: undetectable	1aegA-1y80A: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M24_A_9CRA501_1 (RETINOIC ACID RECEPTOR GAMMA)	1y80	PREDICTED COBALAMIN BINDING PROTEIN (Moorella thermoacetica)	5 / 12	MET A 156 ILE A 160 GLY A 177 LEU A 204 ILE A 142	None None B1M A 301 (-3.5A) None None	1.10A	5m24A-1y80A: undetectable	5m24A-1y80A: 22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_T_PCFT101_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT 9 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL)	1y80	PREDICTED COBALAMIN BINDING PROTEIN (Moorella thermoacetica)	5 / 10	SER A 87 TYR A 120 VAL A 92 GLY A 144 ALA A 186	None None None B1M A 301 (-3.5A) None	1.37A	6hu9L-1y80A: undetectable 6hu9P-1y80A: undetectable 6hu9T-1y80A: undetectable	6hu9L-1y80A: 20.05 6hu9P-1y80A: 25.60 6hu9T-1y80A: 16.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AEG_A_4APA296_1","CYTOCHROME C PEROXIDASE","1y80","PREDICTED COBALAMIN BINDING PROTEIN","Moorella thermoacetica",4,"HIS A 101;GLY A 178;LEU A 149;ASP A  99","B1M A 301 (-3.6A);B1M A 301 (-3.2A);B1M A 301 (-4.3A);B1M A 301 (-4.2A)","0.85A","1aegA-1y80A:undetectable",null],["5M24_A_9CRA501_1","RETINOIC ACID RECEPTOR GAMMA","1y80","PREDICTED COBALAMIN BINDING PROTEIN","Moorella thermoacetica",5,"MET A 156;ILE A 160;GLY A 177;LEU A 204;ILE A 142","None;None;B1M A 301 (-3.5A);None;None","1.10A","5m24A-1y80A:undetectable","1aegA-1y80A:22.11"],["6HU9_T_PCFT101_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL;CYTOCHROME B-C1 COMPLEX SUBUNIT 9;CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL","1y80","PREDICTED COBALAMIN BINDING PROTEIN","Moorella thermoacetica",5,"SER A  87;TYR A 120;VAL A  92;GLY A 144;ALA A 186","None;None;None;B1M A 301 (-3.5A);None","1.37A","6hu9L-1y80A:undetectable;6hu9P-1y80A:undetectable;6hu9T-1y80A:undetectable","5m24A-1y80A:22.88"]]