SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'B1C'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU9_B_SPMB700_1 (POLYAMINE OXIDASE)	5tu4	PAGF PRENYLTRANSFERASE (Planktothrix agardhii)	4 / 7	GLU A 51 TYR A 186 TYR A 235 TYR A 292	B1C A 403 (-2.9A) DST A 401 (-4.3A) DST A 401 (-3.4A) None	1.18A	3ku9B-5tu4A: undetectable	3ku9B-5tu4A: 20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5tu4	PAGF PRENYLTRANSFERASE (Planktothrix agardhii)	3 / 3	GLU A 188 ALA A 187 PHE A 222	B1C A 403 ( 4.2A) None DST A 401 ( 4.5A)	0.68A	4v1fA-5tu4A: undetectable	4v1fA-5tu4A: 15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5tu4	PAGF PRENYLTRANSFERASE (Planktothrix agardhii)	3 / 3	GLU A 188 ALA A 187 PHE A 222	B1C A 403 ( 4.2A) None DST A 401 ( 4.5A)	0.66A	4v1fC-5tu4A: undetectable	4v1fC-5tu4A: 15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K7U_A_SAMA601_0 (N6-ADENOSINE-METHYLT RANSFERASE 70 KDA SUBUNIT)	5tu4	PAGF PRENYLTRANSFERASE (Planktothrix agardhii)	5 / 12	ILE A 19 LEU A 34 GLU A 51 PHE A 66 HIS A 138	None None B1C A 403 (-2.9A) None B1C A 403 ( 3.5A)	1.21A	5k7uA-5tu4A: undetectable	5k7uA-5tu4A: 21.82

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KU9_B_SPMB700_1","POLYAMINE OXIDASE","5tu4","PAGF PRENYLTRANSFERASE","Planktothrix agardhii",4,"GLU A  51;TYR A 186;TYR A 235;TYR A 292","B1C A 403 (-2.9A);DST A 401 (-4.3A);DST A 401 (-3.4A);None","1.18A","3ku9B-5tu4A:undetectable",null],["4V1F_A_BQ1A1087_0","F0F1 ATP SYNTHASE SUBUNIT C","5tu4","PAGF PRENYLTRANSFERASE","Planktothrix agardhii",3,"GLU A 188;ALA A 187;PHE A 222","B1C A 403 ( 4.2A);None;DST A 401 ( 4.5A)","0.68A","4v1fA-5tu4A:undetectable","3ku9B-5tu4A:20.46"],["4V1F_C_BQ1C1087_0","F0F1 ATP SYNTHASE SUBUNIT C","5tu4","PAGF PRENYLTRANSFERASE","Planktothrix agardhii",3,"GLU A 188;ALA A 187;PHE A 222","B1C A 403 ( 4.2A);None;DST A 401 ( 4.5A)","0.66A","4v1fC-5tu4A:undetectable","4v1fA-5tu4A:15.30"],["5K7U_A_SAMA601_0","N6-ADENOSINE-METHYLTRANSFERASE 70 KDA SUBUNIT","5tu4","PAGF PRENYLTRANSFERASE","Planktothrix agardhii",5,"ILE A  19;LEU A  34;GLU A  51;PHE A  66;HIS A 138","None;None;B1C A 403 (-2.9A);None;B1C A 403 ( 3.5A)","1.21A","5k7uA-5tu4A:undetectable","4v1fC-5tu4A:15.30"]]