SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AZ8'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1C6Y_B_MK1B524_2 (PROTEIN (PROTEASE)) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.82A | 1c6yB-5ufmA:undetectable | 1c6yB-5ufmA:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1FDS_A_ESTA350_1 (17-BETA-HYDROXYSTEROID-DEHYDROGENASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | TYR A 149GLY A 136TYR A 28PHE A 36PHE A 168 | NoneAZ8 A 302 ( 3.5A)NoneSAH A 301 (-3.4A)AZ8 A 302 (-4.8A) | 1.24A | 1fdsA-5ufmA:6.2 | 1fdsA-5ufmA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1HSG_B_MK1B902_2 (HIV-1 PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.75A | 1hsgB-5ufmA:undetectable | 1hsgB-5ufmA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1K6C_B_MK1B902_2 (POL POLYPROTEIN) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.80A | 1k6cB-5ufmA:undetectable | 1k6cB-5ufmA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1SDT_B_MK1B902_2 (PROTEASE RETROPEPSIN) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.81A | 1sdtB-5ufmA:undetectable | 1sdtB-5ufmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1SDV_B_MK1B902_2 (PROTEASE RETROPEPSIN) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 11 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.81A | 1sdvB-5ufmA:undetectable | 1sdvB-5ufmA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2AVO_B_MK1B902_2 (POL POLYPROTEIN) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.79A | 2avoB-5ufmA:undetectable | 2avoB-5ufmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2BPX_B_MK1B902_2 (HIV-1 PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.79A | 2bpxB-5ufmA:undetectable | 2bpxB-5ufmA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2F80_B_017B301_1 (POL POLYPROTEIN) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.80A | 2f80A-5ufmA:undetectable | 2f80A-5ufmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2F81_A_017A302_1 (POL POLYPROTEIN) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.79A | 2f81A-5ufmA:undetectable | 2f81A-5ufmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2F81_A_017A302_2 (POL POLYPROTEIN) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.81A | 2f81B-5ufmA:undetectable | 2f81B-5ufmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2F8G_B_017B401_1 (POL POLYPROTEIN) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.83A | 2f8gA-5ufmA:undetectable | 2f8gA-5ufmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2IEN_B_017B402_2 (PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.82A | 2ienB-5ufmA:undetectable | 2ienB-5ufmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2IGT_C_SAMC1003_1 (SAM DEPENDENTMETHYLTRANSFERASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 4 / 4 | ASP A 95ASP A 72ASP A 45GLY A 136 | SAH A 301 (-2.7A)NoneNoneAZ8 A 302 ( 3.5A) | 1.39A | 2igtC-5ufmA:13.9 | 2igtC-5ufmA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PYM_A_1UNA1001_1 (PROTEASE RETROPEPSIN) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.81A | 2pymA-5ufmA:undetectable | 2pymA-5ufmA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Q5K_A_AB1A201_2 (PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.87A | 2q5kB-5ufmA:undetectable | 2q5kB-5ufmA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3CYW_A_017A201_1 (HIV-1 PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.84A | 3cywA-5ufmA:undetectable | 3cywA-5ufmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3CYW_A_017A201_2 (HIV-1 PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.81A | 3cywB-5ufmA:undetectable | 3cywB-5ufmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3EKT_B_017B200_1 (PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 9 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.91A | 3ektA-5ufmA:undetectable | 3ektA-5ufmA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3EKV_A_478A200_1 (PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 10 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.84A | 3ekvA-5ufmA:undetectable | 3ekvA-5ufmA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3EKX_B_1UNB201_1 (PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 11 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.84A | 3ekxA-5ufmA:undetectable | 3ekxA-5ufmA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LZU_A_017A200_1 (HIV-1 PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.83A | 3lzuA-5ufmA:undetectable | 3lzuA-5ufmA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OXC_A_ROCA401_1 (PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.88A | 3oxcA-5ufmA:undetectable | 3oxcA-5ufmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OXW_B_017B200_1 (HIV-1 PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 10 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.84A | 3oxwA-5ufmA:undetectable | 3oxwA-5ufmA:17.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4DQC_A_017A101_2 (ASPARTYL PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 9 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.90A | 4dqcB-5ufmA:undetectable | 4dqcB-5ufmA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LL3_A_017A201_2 (PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 10 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.85A | 4ll3B-5ufmA:undetectable | 4ll3B-5ufmA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LL3_A_017A202_1 (PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 10 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.82A | 4ll3A-5ufmA:undetectable | 4ll3A-5ufmA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4NJV_A_RITA500_2 (PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 11 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.86A | 4njvB-5ufmA:undetectable | 4njvB-5ufmA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5U63_A_ACTA406_0 (THIOREDOXINREDUCTASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 3 / 3 | HIS A 139SER A 166ARG A 212 | AZ8 A 302 (-4.5A)NoneAZ8 A 302 (-3.9A) | 0.65A | 5u63A-5ufmA:2.4 | 5u63A-5ufmA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5WY0_A_SAMA800_0 (SMALL RNA2'-O-METHYLTRANSFERASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | GLY A 74GLY A 76ASP A 95VAL A 120HIS A 140 | SAH A 301 (-3.6A)SAH A 301 (-3.6A)SAH A 301 (-2.7A)SAH A 301 (-4.1A)AZ8 A 302 (-4.0A) | 0.62A | 5wy0A-5ufmA:13.7 | 5wy0A-5ufmA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6DJ1_B_AB1B201_1 (HIV-1 PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.89A | 6dj1B-5ufmA:undetectable | 6dj1B-5ufmA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6DJ2_B_AB1B201_1 (HIV-1 PROTEASE) |
5ufm | METHYLTRANSFERASEDOMAIN PROTEIN (Burkholderiathailandensis) | 5 / 12 | ASP A 95GLY A 76ASP A 72VAL A 120GLY A 136 | SAH A 301 (-2.7A)SAH A 301 (-3.6A)NoneSAH A 301 (-4.1A)AZ8 A 302 ( 3.5A) | 0.90A | 6dj2B-5ufmA:undetectable | 6dj2B-5ufmA:17.98 |