SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AWH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3zei O-ACETYLSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		3 / 3 MET A  98
ASN A  74
GLN A 144
 None
PLP  A1301 (-3.8A)
AWH  A1302 (-3.3A)
 0.90A 1xoqB-3zeiA:
undetectable		 1xoqB-3zeiA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3zei O-ACETYLSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 270
VAL A 291
GLN A 144
THR A 179
ASP A 294
 None
None
AWH  A1302 (-3.3A)
PLP  A1301 (-2.8A)
PLP  A1301 (-3.3A)
 1.21A 2v95A-3zeiA:
undetectable		 2v95A-3zeiA:
20.26