SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AVD'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM
(Homo
sapiens) 		4 / 7 ASP A 306
PHE A 196
TYR A  83
THR A 240
 AVD  A 833 ( 4.9A)
AVD  A 833 (-4.2A)
None
None
 1.39A 2q6kA-3cemA:
undetectable		 2q6kA-3cemA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM
(Homo
sapiens) 		4 / 7 ARG A 310
TYR A 157
LEU A 144
TYR A  83
 AVD  A 833 (-4.0A)
None
None
None
 1.36A 6g2pA-3cemA:
2.7		 6g2pA-3cemA:
19.77