SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AT2'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M8D_A_CLWA906_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	PRO A 350 VAL A 352 TYR A 373 MET A 374	AT2  A 906 (-4.5A) AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A)	0.18A	1m8dA-3e7gA: 60.4	1m8dA-3e7gA: 87.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M8D_A_CLWA906_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	VAL A 352 TYR A 373 MET A 374 GLU A 377	AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A) AT2  A 906 ( 2.7A)	1.18A	1m8dA-3e7gA: 60.4	1m8dA-3e7gA: 87.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M8D_B_CLWB907_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	PRO A 350 VAL A 352 TYR A 373 MET A 374	AT2  A 906 (-4.5A) AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A)	0.19A	1m8dB-3e7gA: 60.2	1m8dB-3e7gA: 87.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_A_CLWA906_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	PRO A 350 VAL A 352 TYR A 373 MET A 374	AT2  A 906 (-4.5A) AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A)	0.31A	1m9jA-3e7gA: 55.2	1m9jA-3e7gA: 60.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_A_CLWA906_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	VAL A 352 TYR A 373 MET A 374 GLU A 377	AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A) AT2  A 906 ( 2.7A)	1.25A	1m9jA-3e7gA: 55.2	1m9jA-3e7gA: 60.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_B_CLWB907_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	PRO A 350 VAL A 352 TYR A 373 MET A 374	AT2  A 906 (-4.5A) AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A)	0.24A	1m9jB-3e7gA: 55.3	1m9jB-3e7gA: 60.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1M9J_B_CLWB907_1 (ENDOTHELIAL NITRIC-OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	VAL A 352 TYR A 373 MET A 374 GLU A 377	AT2  A 906 ( 4.8A) None HEM  A 901 ( 4.6A) AT2  A 906 ( 2.7A)	1.18A	1m9jB-3e7gA: 55.3	1m9jB-3e7gA: 60.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1P6K_A_MTLA870_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.14A	1p6kA-3e7gA: 57.0	1p6kA-3e7gA: 65.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1P6K_B_MTLB871_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.16A	1p6kB-3e7gA: 57.3	1p6kB-3e7gA: 65.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1RS6_A_MTLA870_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.09A	1rs6A-3e7gA: 56.7	1rs6A-3e7gA: 65.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1RS6_B_MTLB871_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.11A	1rs6B-3e7gA: 57.0	1rs6B-3e7gA: 65.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1RS7_B_MTLB871_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.15A	1rs7B-3e7gA: 57.1	1rs7B-3e7gA: 65.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1ZZQ_A_MTLA870_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.10A	1zzqA-3e7gA: 57.2	1zzqA-3e7gA: 65.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1ZZQ_B_MTLB871_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.15A	1zzqB-3e7gA: 57.4	1zzqB-3e7gA: 65.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1ZZU_A_MTLA870_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.03A	1zzuA-3e7gA: 57.3	1zzuA-3e7gA: 65.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1ZZU_B_MTLB871_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.17A	1zzuB-3e7gA: 57.6	1zzuB-3e7gA: 65.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DL9_A_V2HA602_0 (CYTOCHROME P450 2R1)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	5 / 12	VAL A 422 GLU A 377 VAL A 475 ILE A 201 THR A 473	None AT2  A 906 ( 2.7A) None None None	1.19A	3dl9A-3e7gA: undetectable	3dl9A-3e7gA: 23.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3N62_A_MTLA870_0 (NITRIC OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.01A	3n62A-3e7gA: 57.1	3n62A-3e7gA: 65.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3N62_B_MTLB870_0 (NITRIC OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.04A	3n62B-3e7gA: 57.4	3n62B-3e7gA: 65.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3N66_B_MTLB870_0 (NITRIC OXIDE SYNTHASE)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.04A	3n66B-3e7gA: 57.4	3n66B-3e7gA: 65.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4D33_A_MTLA870_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	5 / 8	ARG A 266 ASN A 283 GLU A 285 ASN A 354 TRP A 496	AT2  A 906 (-3.6A) None None None None	1.00A	4d33A-3e7gA: 54.1	4d33A-3e7gA: 58.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4D33_B_MTLB870_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 7	ARG A 266 ASN A 283 GLU A 285 ASN A 354	AT2  A 906 (-3.6A) None None None	1.02A	4d33B-3e7gA: 54.4	4d33B-3e7gA: 58.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4D39_A_MTLA870_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 GLU A 285 ASN A 354	AT2  A 906 (-3.6A) None None None	1.06A	4d39A-3e7gA: 55.5	4d39A-3e7gA: 58.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4D39_A_MTLA870_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 GLU A 285 ASN A 354 TRP A 496	AT2  A 906 (-3.6A) None None None	0.85A	4d39A-3e7gA: 55.5	4d39A-3e7gA: 58.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4D39_B_MTLB870_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 7	ARG A 266 ASN A 283 GLU A 285 ASN A 354	AT2  A 906 (-3.6A) None None None	1.08A	4d39B-3e7gA: 55.7	4d39B-3e7gA: 58.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4KCN_A_MTLA804_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	6 / 6	ARG A 266 GLU A 377 ARG A 381 ASP A 382 ASP A 385 ARG A 388	AT2  A 906 (-3.6A) AT2  A 906 ( 2.7A) H4B  A 902 (-3.9A) AT2  A 906 (-4.4A) None AT2  A 906 (-3.1A)	0.50A	4kcnA-3e7gA: 57.2	4kcnA-3e7gA: 65.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4KCN_B_MTLB805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	6 / 6	ARG A 266 GLU A 377 ARG A 381 ASP A 382 ASP A 385 ARG A 388	AT2  A 906 (-3.6A) AT2  A 906 ( 2.7A) H4B  A 902 (-3.9A) AT2  A 906 (-4.4A) None AT2  A 906 (-3.1A)	0.51A	4kcnB-3e7gA: 57.5	4kcnB-3e7gA: 65.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5VUN_A_MTLA805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.02A	5vunA-3e7gA: 57.3	5vunA-3e7gA: 65.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5VUN_B_MTLB805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.05A	5vunB-3e7gA: 57.6	5vunB-3e7gA: 65.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5VUO_B_MTLB805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	5 / 8	ARG A 266 ASN A 283 PHE A 286 ASN A 354 TRP A 496	AT2  A 906 (-3.6A) None None None None	1.11A	5vuoB-3e7gA: 57.5	5vuoB-3e7gA: 65.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6AUU_B_MTLB805_0 (NITRIC OXIDE SYNTHASE, BRAIN)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 8	ARG A 266 ASN A 283 PHE A 286 TRP A 496	AT2  A 906 (-3.6A) None None None	1.05A	6auuB-3e7gA: 57.4	6auuB-3e7gA: 65.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWD_B_GLYB709_0 (DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1)	3e7g	NITRIC OXIDE SYNTHASE, INDUCIBLE (Homo sapiens)	4 / 5	GLY A 269 ASN A 283 ASP A 280 ARG A 266	None None None AT2  A 906 (-3.6A)	1.32A	6dwdB-3e7gA: undetectable 6dwdD-3e7gA: undetectable	6dwdB-3e7gA: 22.02 6dwdD-3e7gA: 22.02