SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ASB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 1qq6 PROTEIN
(L-2-HALOACID
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		3 / 3 PRO A  94
PHE A   7
LYS A   9
 None
None
ASB  A   8 ( 3.3A)
 1.22A 3bjwG-1qq6A:
undetectable		 3bjwG-1qq6A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1qq6 PROTEIN
(L-2-HALOACID
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 8 ASP A 176
TYR A 153
VAL A 170
LEU A 168
 ASB  A   8 ( 4.0A)
None
None
None
 1.08A 3jq7C-1qq6A:
5.8		 3jq7C-1qq6A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1qq6 PROTEIN
(L-2-HALOACID
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		4 / 8 SER A 172
LEU A 113
ALA A 180
SER A 171
 ASB  A   8 ( 4.8A)
None
None
ASB  A   8 ( 2.8A)
 0.95A 4ikjA-1qq6A:
undetectable
4ikjB-1qq6A:
undetectable		 4ikjA-1qq6A:
19.28
4ikjB-1qq6A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 4cf3 L-HALOACID
DEHALOGENASE
(Rhodobacteraceae) 		5 / 12 PHE A 144
ALA A 146
LEU A  23
GLY A  13
LEU A 113
 None
None
ASB  A  18 ( 3.8A)
None
None
 1.22A 4kykA-4cf3A:
undetectable
4kykB-4cf3A:
undetectable		 4kykA-4cf3A:
23.29
4kykB-4cf3A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_ACTA605_0
(SERUM ALBUMIN)		 4cf3 L-HALOACID
DEHALOGENASE
(Rhodobacteraceae) 		3 / 3 LYS A  19
LYS A 157
ALA A 181
 ASB  A  18 ( 3.4A)
ASB  A  18 ( 2.8A)
ASB  A  18 ( 3.5A)
 1.20A 4ot2A-4cf3A:
1.3		 4ot2A-4cf3A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_ACTA605_0
(SERUM ALBUMIN)		 4cf3 L-HALOACID
DEHALOGENASE
(Rhodobacteraceae) 		3 / 3 LYS A  19
LYS A 157
ALA A 183
 ASB  A  18 ( 3.4A)
ASB  A  18 ( 2.8A)
ASB  A  18 (-4.5A)
 1.50A 4ot2A-4cf3A:
1.3		 4ot2A-4cf3A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 1qq6 PROTEIN
(L-2-HALOACID
DEHALOGENASE)
(Xanthobacter
autotrophicus) 		5 / 10 ASP A 176
PHE A 185
GLU A 157
VAL A 156
ILE A 138
 ASB  A   8 ( 4.0A)
None
None
None
None
 1.36A 4qt3A-1qq6A:
undetectable		 4qt3A-1qq6A:
19.07