SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ARF'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4mhl INTERLEUKIN-11
(Homo
sapiens) 		3 / 3 LEU A 122
HIS A 175
ILE A 171
 None
ARF  A 203 (-4.4A)
ARF  A 203 (-4.5A)
 0.69A 1s9pB-4mhlA:
undetectable		 1s9pB-4mhlA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 4mhl INTERLEUKIN-11
(Homo
sapiens) 		5 / 12 GLY A 169
GLY A 170
LEU A 119
LEU A 178
HIS A  70
 None
None
None
None
ARF  A 203 (-3.6A)
 1.30A 1ya4B-4mhlA:
undetectable		 1ya4B-4mhlA:
18.30