SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ARC'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HYT_A_OBNA1104_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	1brr	PROTEIN (BACTERIORHODOPSIN) (Halobacterium salinarum)	5 / 12	GLU A 161 LEU A 152 THR A 107 ILE A 108 ARG A 175	None None ARC A1000 (-3.7A) None None	1.16A	4hytA-1brrA: 3.1	4hytA-1brrA: 12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HYT_C_OBNC2004_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	1brr	PROTEIN (BACTERIORHODOPSIN) (Halobacterium salinarum)	5 / 12	GLU A 161 LEU A 152 THR A 107 ILE A 108 ARG A 175	None None ARC A1000 (-3.7A) None None	1.15A	4hytC-1brrA: 0.0	4hytC-1brrA: 12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D4U_C_SAMC301_0 (UNCHARACTERIZED PROTEIN MJ0489)	1brr	PROTEIN (BACTERIORHODOPSIN) (Halobacterium salinarum)	5 / 12	TYR A 185 TRP A 189 ILE A 148 GLY A 116 ILE A 117	RET A 999 (-3.5A) RET A 999 ( 4.3A) None ARC A1002 ( 3.8A) ARC A1002 (-4.6A)	0.99A	5d4uC-1brrA: undetectable	5d4uC-1brrA: 24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D4U_D_SAMD301_0 (UNCHARACTERIZED PROTEIN MJ0489)	1brr	PROTEIN (BACTERIORHODOPSIN) (Halobacterium salinarum)	5 / 12	TYR A 185 TRP A 189 ILE A 148 GLY A 116 ILE A 117	RET A 999 (-3.5A) RET A 999 ( 4.3A) None ARC A1002 ( 3.8A) ARC A1002 (-4.6A)	0.95A	5d4uD-1brrA: undetectable	5d4uD-1brrA: 24.09

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4HYT_A_OBNA1104_1","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","1brr","PROTEIN (BACTERIORHODOPSIN)","Halobacterium salinarum",5,"GLU A 161;LEU A 152;THR A 107;ILE A 108;ARG A 175","None;None;ARC A1000 (-3.7A);None;None","1.16A","4hytA-1brrA:3.1",null],["4HYT_C_OBNC2004_1","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","1brr","PROTEIN (BACTERIORHODOPSIN)","Halobacterium salinarum",5,"GLU A 161;LEU A 152;THR A 107;ILE A 108;ARG A 175","None;None;ARC A1000 (-3.7A);None;None","1.15A","4hytC-1brrA:0.0","4hytA-1brrA:12.84"],["5D4U_C_SAMC301_0","UNCHARACTERIZED PROTEIN MJ0489","1brr","PROTEIN (BACTERIORHODOPSIN)","Halobacterium salinarum",5,"TYR A 185;TRP A 189;ILE A 148;GLY A 116;ILE A 117","RET A 999 (-3.5A);RET A 999 ( 4.3A);None;ARC A1002 ( 3.8A);ARC A1002 (-4.6A)","0.99A","5d4uC-1brrA:undetectable","4hytC-1brrA:12.84"],["5D4U_D_SAMD301_0","UNCHARACTERIZED PROTEIN MJ0489","1brr","PROTEIN (BACTERIORHODOPSIN)","Halobacterium salinarum",5,"TYR A 185;TRP A 189;ILE A 148;GLY A 116;ILE A 117","RET A 999 (-3.5A);RET A 999 ( 4.3A);None;ARC A1002 ( 3.8A);ARC A1002 (-4.6A)","0.95A","5d4uD-1brrA:undetectable","5d4uC-1brrA:24.09"]]