SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'APG'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J2P_F_SC2F1291_1 (FICOLIN-2)	1mns	MANDELATE RACEMASE (Pseudomonas putida)	4 / 6	SER A 139 LEU A 319 ASP A 195 GLU A 247	APG A 361 (-3.6A) None MG A 360 (-2.5A) MG A 360 (-2.5A)	1.10A	2j2pE-1mnsA: 0.0 2j2pF-1mnsA: 0.0	2j2pE-1mnsA: 18.84 2j2pF-1mnsA: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZB7_A_NCAA901_0 (PROSTAGLANDIN REDUCTASE 2)	1mns	MANDELATE RACEMASE (Pseudomonas putida)	4 / 5	TYR A 54 MET A 272 LEU A 321 LEU A 298	None None None APG A 361 ( 4.9A)	1.15A	2zb7A-1mnsA: undetectable	2zb7A-1mnsA: 22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G0V_D_MIXD101_1 (DNA TOPOISOMERASE 2-BETA)	1mns	MANDELATE RACEMASE (Pseudomonas putida)	4 / 6	GLY A 246 ASN A 197 GLU A 221 MET A 109	None APG A 361 (-3.1A) MG A 360 (-3.0A) None	1.29A	4g0vB-1mnsA: undetectable	4g0vB-1mnsA: 17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FHW_A_ACRA801_2 (GLUCOAMYLASE P)	1mns	MANDELATE RACEMASE (Pseudomonas putida)	3 / 3	TRP A 219 GLU A 222 GLU A 317	None None APG A 361 ( 2.9A)	0.99A	6fhwA-1mnsA: undetectable	6fhwA-1mnsA: 13.97

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2J2P_F_SC2F1291_1","FICOLIN-2;FICOLIN-2","1mns","MANDELATE RACEMASE","Pseudomonas putida",4,"SER A 139;LEU A 319;ASP A 195;GLU A 247","APG A 361 (-3.6A);None; MG A 360 (-2.5A); MG A 360 (-2.5A)","1.10A","2j2pE-1mnsA:0.0;2j2pF-1mnsA:0.0",null],["2ZB7_A_NCAA901_0","PROSTAGLANDIN REDUCTASE 2","1mns","MANDELATE RACEMASE","Pseudomonas putida",4,"TYR A  54;MET A 272;LEU A 321;LEU A 298","None;None;None;APG A 361 ( 4.9A)","1.15A","2zb7A-1mnsA:undetectable","2j2pE-1mnsA:18.84;2j2pF-1mnsA:18.84"],["4G0V_D_MIXD101_1","DNA TOPOISOMERASE 2-BETA","1mns","MANDELATE RACEMASE","Pseudomonas putida",4,"GLY A 246;ASN A 197;GLU A 221;MET A 109","None;APG A 361 (-3.1A); MG A 360 (-3.0A);None","1.29A","4g0vB-1mnsA:undetectable","2zb7A-1mnsA:22.99"],["6FHW_A_ACRA801_2","GLUCOAMYLASE P","1mns","MANDELATE RACEMASE","Pseudomonas putida",3,"TRP A 219;GLU A 222;GLU A 317","None;None;APG A 361 ( 2.9A)","0.99A","6fhwA-1mnsA:undetectable","4g0vB-1mnsA:17.87"]]