SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AOG'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XF3_A_J01A500_1 (ORF12)	1r82	GLYCOPROTEIN-FUCOSYL GALACTOSIDE ALPHA-GALACTOSYLTRAN SFERASE (Homo sapiens)	5 / 10	VAL A 277 LEU A 324 LEU A 306 GLY A 267 ALA A 268	None AOG A 452 ( 4.2A) HG A 402 ( 4.2A) None None	1.25A	2xf3A-1r82A: undetectable	2xf3A-1r82A: 21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZQT_A_30ZA1920_1 (ANDROGEN RECEPTOR)	1r82	GLYCOPROTEIN-FUCOSYL GALACTOSIDE ALPHA-GALACTOSYLTRAN SFERASE (Homo sapiens)	4 / 6	GLY A 230 LEU A 310 ASN A 307 GLU A 303	None None None AOG A 452 (-2.6A)	1.00A	3zqtA-1r82A: undetectable	3zqtA-1r82A: 21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BYK_A_OAQA302_0 (SULFOTRANSFERASE)	1r82	GLYCOPROTEIN-FUCOSYL GALACTOSIDE ALPHA-GALACTOSYLTRAN SFERASE (Homo sapiens)	5 / 12	ILE A 224 LEU A 324 VAL A 210 LEU A 225 PHE A 229	None AOG A 452 ( 4.2A) None None None	1.08A	5bykA-1r82A: 0.0	5bykA-1r82A: 20.58