SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ANN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 5oc1 ARYL-ALCOHOL OXIDASE
(Pleurotus
eryngii) 		5 / 10 MET A  96
ALA A 199
ARG A 206
ILE A 500
LEU A 361
 None
None
None
ANN  A 601 (-4.4A)
GOL  A 606 ( 4.9A)
 1.30A 1a52A-5oc1A:
undetectable		 1a52A-5oc1A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA602_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 5oc1 ARYL-ALCOHOL OXIDASE
(Pleurotus
eryngii) 		4 / 5 HIS A 313
ILE A 500
PRO A 503
ASP A 312
 None
ANN  A 601 (-4.4A)
GOL  A 605 (-3.4A)
None
 1.17A 2f7fA-5oc1A:
0.5		 2f7fA-5oc1A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 5oc1 ARYL-ALCOHOL OXIDASE
(Pleurotus
eryngii) 		5 / 12 MET A  96
ALA A 199
ARG A 206
ILE A 500
LEU A 361
 None
None
None
ANN  A 601 (-4.4A)
GOL  A 606 ( 4.9A)
 1.11A 2qxsB-5oc1A:
undetectable		 2qxsB-5oc1A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5oc1 ARYL-ALCOHOL OXIDASE
(Pleurotus
eryngii) 		5 / 11 GLN A 176
ALA A 358
PHE A 320
THR A 390
ILE A 391
 None
ANN  A 601 ( 4.9A)
None
None
ANN  A 601 (-3.9A)
 1.43A 3n23A-5oc1A:
undetectable		 3n23A-5oc1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 5oc1 ARYL-ALCOHOL OXIDASE
(Pleurotus
eryngii) 		4 / 6 ILE A 500
PRO A 399
LEU A 315
ASP A 312
 ANN  A 601 (-4.4A)
GOL  A 607 ( 4.3A)
None
None
 1.18A 3oi8A-5oc1A:
undetectable		 3oi8A-5oc1A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5R_A_KANA2002_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 5oc1 ARYL-ALCOHOL OXIDASE
(Pleurotus
eryngii) 		5 / 11 PRO A  51
ASN A  56
ILE A 357
PHE A 501
TYR A  92
 None
None
ANN  A 601 (-3.7A)
FAD  A 602 ( 3.8A)
FAD  A 602 ( 3.8A)
 1.49A 3q5rA-5oc1A:
0.0		 3q5rA-5oc1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5oc1 ARYL-ALCOHOL OXIDASE
(Pleurotus
eryngii) 		5 / 10 ILE A 156
ILE A 391
ALA A 358
LEU A 356
ALA A 355
 None
ANN  A 601 (-3.9A)
ANN  A 601 ( 4.9A)
None
None
 1.27A 5zjiB-5oc1A:
undetectable		 5zjiB-5oc1A:
9.46