SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AND'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXG_A_ACRA442_1 (ALPHA AMYLASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 11	GLY A 212 PHE A 197 GLY A 224 GLY A 120 GLY A 121	None None None AND A 508 ( 3.1A) FAD A 510 (-4.1A)	1.08A	1mxgA-1coyA: undetectable	1mxgA-1coyA: 23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MB5_A_SAMA301_0 (SAM-DEPENDENT METHYLTRANSFERASE)	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 12	VAL A 191 GLY A 121 ALA A 123 ILE A 218 PRO A 364	None FAD A 510 (-4.1A) None FAD A 510 ( 4.6A) AND A 508 ( 4.6A)	0.96A	3mb5A-1coyA: 3.2	3mb5A-1coyA: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_C_CLQC303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	4 / 5	GLY A 214 GLY A 215 MET A 59 GLU A 203	None None AND A 508 ( 4.0A) None	1.21A	4fglC-1coyA: 2.8	4fglC-1coyA: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LBT_A_6T0A304_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1coy	CHOLESTEROL OXIDASE (Brevibacterium sterolicum)	5 / 10	GLY A 214 GLY A 215 MET A 59 GLU A 203 ILE A 343	None None AND A 508 ( 4.0A) None None	1.43A	5lbtA-1coyA: 3.0 5lbtB-1coyA: 2.9	5lbtA-1coyA: 17.67 5lbtB-1coyA: 17.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MXG_A_ACRA442_1","ALPHA AMYLASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"GLY A 212;PHE A 197;GLY A 224;GLY A 120;GLY A 121","None;None;None;AND A 508 ( 3.1A);FAD A 510 (-4.1A)","1.08A","1mxgA-1coyA:undetectable",null],["3MB5_A_SAMA301_0","SAM-DEPENDENT METHYLTRANSFERASE","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"VAL A 191;GLY A 121;ALA A 123;ILE A 218;PRO A 364","None;FAD A 510 (-4.1A);None;FAD A 510 ( 4.6A);AND A 508 ( 4.6A)","0.96A","3mb5A-1coyA:3.2","1mxgA-1coyA:23.24"],["4FGL_C_CLQC303_0","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",4,"GLY A 214;GLY A 215;MET A  59;GLU A 203","None;None;AND A 508 ( 4.0A);None","1.21A","4fglC-1coyA:2.8","3mb5A-1coyA:18.79"],["5LBT_A_6T0A304_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","1coy","CHOLESTEROL OXIDASE","Brevibacterium sterolicum",5,"GLY A 214;GLY A 215;MET A  59;GLU A 203;ILE A 343","None;None;AND A 508 ( 4.0A);None;None","1.43A","5lbtA-1coyA:3.0;5lbtB-1coyA:2.9","4fglC-1coyA:19.07"]]