SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ALL'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOD_C_RFPC2002_1 (ACRIFLAVINE RESISTANCE PROTEIN B)	5dte	MONOSACCHARIDE-TRANS PORTING ATPASE (Actinobacillus succinogenes)	5 / 12	ALA A 225 THR A 269 PHE A 43 ASN A 140 GLY A 143	None None ALL A 401 ( 4.9A) ALL A 401 ( 4.9A) None	1.47A	3aodC-5dteA: undetectable	3aodC-5dteA: 14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G0V_A_MIXA1301_1 (DNA TOPOISOMERASE 2-BETA)	5dte	MONOSACCHARIDE-TRANS PORTING ATPASE (Actinobacillus succinogenes)	4 / 7	ARG A 176 GLY A 143 ASN A 268 GLU A 147	ALL A 401 (-2.9A) None None None	0.94A	4g0vA-5dteA: undetectable	4g0vA-5dteA: 18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G0V_D_MIXD101_1 (DNA TOPOISOMERASE 2-BETA)	5dte	MONOSACCHARIDE-TRANS PORTING ATPASE (Actinobacillus succinogenes)	4 / 6	ARG A 176 GLY A 143 ASN A 268 GLU A 147	ALL A 401 (-2.9A) None None None	1.05A	4g0vB-5dteA: undetectable	4g0vB-5dteA: 18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GQB_A_GCSA602_1 (CHITINASE)	5dte	MONOSACCHARIDE-TRANS PORTING ATPASE (Actinobacillus succinogenes)	3 / 3	TRP A 200 GLU A 69 ASP A 118	ALL A 401 (-3.6A) ALL A 401 (-3.3A) ALL A 401 (-3.0A)	1.01A	5gqbA-5dteA: undetectable	5gqbA-5dteA: 20.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3AOD_C_RFPC2002_1","ACRIFLAVINE RESISTANCE PROTEIN B","5dte","MONOSACCHARIDE-TRANSPORTING ATPASE","Actinobacillus succinogenes",5,"ALA A 225;THR A 269;PHE A  43;ASN A 140;GLY A 143","None;None;ALL A 401 ( 4.9A);ALL A 401 ( 4.9A);None","1.47A","3aodC-5dteA:undetectable",null],["4G0V_A_MIXA1301_1","DNA TOPOISOMERASE 2-BETA","5dte","MONOSACCHARIDE-TRANSPORTING ATPASE","Actinobacillus succinogenes",4,"ARG A 176;GLY A 143;ASN A 268;GLU A 147","ALL A 401 (-2.9A);None;None;None","0.94A","4g0vA-5dteA:undetectable","3aodC-5dteA:14.82"],["4G0V_D_MIXD101_1","DNA TOPOISOMERASE 2-BETA","5dte","MONOSACCHARIDE-TRANSPORTING ATPASE","Actinobacillus succinogenes",4,"ARG A 176;GLY A 143;ASN A 268;GLU A 147","ALL A 401 (-2.9A);None;None;None","1.05A","4g0vB-5dteA:undetectable","4g0vA-5dteA:18.98"],["5GQB_A_GCSA602_1","CHITINASE","5dte","MONOSACCHARIDE-TRANSPORTING ATPASE","Actinobacillus succinogenes",3,"TRP A 200;GLU A  69;ASP A 118","ALL A 401 (-3.6A);ALL A 401 (-3.3A);ALL A 401 (-3.0A)","1.01A","5gqbA-5dteA:undetectable","4g0vB-5dteA:18.98"]]