SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AKR'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MRL_C_DOLC302_1 (STREPTOGRAMIN A ACETYLTRANSFERASE)	4kem	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME (Azospirillum lipoferum)	5 / 10	VAL A 345 TYR A 342 TYR A  56 HIS A 321 ASN A 214	None AKR  A 405 (-4.7A) None AKR  A 405 (-4.6A) AKR  A 405 ( 3.3A)	1.46A	1mrlA-4kemA: 0.0 1mrlC-4kemA: 0.0	1mrlA-4kemA: 19.11 1mrlC-4kemA: 19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZTH_A_SAMA305_1 (CATECHOL O-METHYLTRANSFERASE)	4kem	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME (Azospirillum lipoferum)	3 / 3	SER A 327 GLU A 340 ASP A 291	None AKR  A 405 (-2.7A) None	0.81A	2zthA-4kemA: 3.1	2zthA-4kemA: 21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BWY_A_SAMA301_1 (COMT PROTEIN)	4kem	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME (Azospirillum lipoferum)	3 / 3	SER A 327 GLU A 340 ASP A 291	None AKR  A 405 (-2.7A) None	0.85A	3bwyA-4kemA: undetectable	3bwyA-4kemA: 20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LRH_D_FOLD301_1 (FOLATE RECEPTOR ALPHA)	4kem	MANDELATE RACEMASE/MUCONATE LACTONIZING ENZYME (Azospirillum lipoferum)	3 / 3	HIS A 321 TRP A 236 SER A  52	AKR  A 405 (-4.6A) None None	1.18A	4lrhD-4kemA: undetectable	4lrhD-4kemA: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PAH_A_LNRA600_1 (PHENYLALANINE HYDROXYLASE)	5y4k	DMSP LYASE DDDY (Acinetobacter bereziniae)	4 / 6	HIS A 265 HIS A 338 TYR A 271 GLU A 269	ZN  A 501 ( 3.3A) ZN  A 501 ( 3.3A) AKR  A 502 (-4.7A) ZN  A 501 ( 2.4A)	1.04A	4pahA-5y4kA: undetectable	4pahA-5y4kA: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWU_B_BEZB1401_0 (MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC)	5gxd	AMP-DEPENDENT SYNTHETASE AND LIGASE (Dinoroseobacter shibae)	4 / 6	GLY A 394 THR A 393 SER A 289 VAL A 285	None None None AKR  A 702 ( 4.4A)	0.99A	5ewuB-5gxdA: 2.4	5ewuB-5gxdA: 20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5PAH_A_LDPA600_1 (PHENYLALANINE 4-MONOOXYGENASE)	5y4k	DMSP LYASE DDDY (Acinetobacter bereziniae)	4 / 4	HIS A 265 HIS A 338 TYR A 271 GLU A 269	ZN  A 501 ( 3.3A) ZN  A 501 ( 3.3A) AKR  A 502 (-4.7A) ZN  A 501 ( 2.4A)	1.03A	5pahA-5y4kA: undetectable	5pahA-5y4kA: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TIX_B_OQRB302_0 (SULFOTRANSFERASE)	4ph9	PROSTAGLANDIN G/H SYNTHASE 2 (Mus musculus)	5 / 10	PRO A 173 MET A 502 ILE A 499 PHE A 479 GLU A 491	None None None AKR  A 609 (-4.6A) None	1.39A	5tixB-4ph9A: undetectable	5tixB-4ph9A: 18.52