SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AKD'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O7G_A_ASCA303_0 (PROBABLE TRANSMEMBRANE ASCORBATE FERRIREDUCTASE 2)	3jup	PHENAZINE BIOSYNTHESIS PROTEIN A/B (Burkholderia lata)	4 / 7	PHE A 124 HIS A 126 TYR A 30 ARG A 41	AKD A 500 ( 4.7A) None None None	1.40A	4o7gA-3jupA: undetectable 4o7gB-3jupA: undetectable	4o7gA-3jupA: 20.50 4o7gB-3jupA: 20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QOG_A_ML1A302_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3jup	PHENAZINE BIOSYNTHESIS PROTEIN A/B (Burkholderia lata)	4 / 8	PHE A 128 ILE A 135 PHE A 141 GLY A 52	None None None AKD A 500 ( 4.7A)	0.97A	4qogA-3jupA: undetectable 4qogB-3jupA: undetectable	4qogA-3jupA: 22.09 4qogB-3jupA: 22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MZJ_A_TEPA2401_1 (ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A)	3jup	PHENAZINE BIOSYNTHESIS PROTEIN A/B (Burkholderia lata)	4 / 8	LEU A 53 MET A 142 ASN A 122 ILE A 110	AKD A 500 ( 4.2A) None None None	0.91A	5mzjA-3jupA: undetectable	5mzjA-3jupA: 16.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4O7G_A_ASCA303_0","PROBABLE TRANSMEMBRANE ASCORBATE FERRIREDUCTASE 2","3jup","PHENAZINE BIOSYNTHESIS PROTEIN A\/B","Burkholderia lata",4,"PHE A 124;HIS A 126;TYR A  30;ARG A  41","AKD A 500 ( 4.7A);None;None;None","1.40A","4o7gA-3jupA:undetectable;4o7gB-3jupA:undetectable",null],["4QOG_A_ML1A302_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","3jup","PHENAZINE BIOSYNTHESIS PROTEIN A\/B","Burkholderia lata",4,"PHE A 128;ILE A 135;PHE A 141;GLY A  52","None;None;None;AKD A 500 ( 4.7A)","0.97A","4qogA-3jupA:undetectable;4qogB-3jupA:undetectable","4o7gA-3jupA:20.50;4o7gB-3jupA:20.50"],["5MZJ_A_TEPA2401_1","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","3jup","PHENAZINE BIOSYNTHESIS PROTEIN A\/B","Burkholderia lata",4,"LEU A  53;MET A 142;ASN A 122;ILE A 110","AKD A 500 ( 4.2A);None;None;None","0.91A","5mzjA-3jupA:undetectable","4qogA-3jupA:22.09;4qogB-3jupA:22.09"]]