SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AJP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN
(Mus
musculus;
Rattus
norvegicus) 		5 / 12 TYR A 135
ASP A 195
GLN A 129
GLU A 126
ILE A 222
 None
None
AJP  A1302 (-3.6A)
None
None
 1.12A 1fkbA-5welA:
undetectable		 1fkbA-5welA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN
(Mus
musculus;
Rattus
norvegicus) 		4 / 5 ILE A 358
HIS A 219
TYR A 135
VAL A 149
 None
AJP  A1302 (-4.3A)
None
None
 1.03A 4s0vA-5welA:
4.7		 4s0vA-5welA:
18.91