SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AIX'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 3ita D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC
(Escherichia
coli) 		3 / 3 TRP A 254
ARG A 244
THR A 253
 None
AIX  A 500 (-3.0A)
None
 0.95A 1df7A-3itaA:
undetectable		 1df7A-3itaA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
LYS A  72
SER A 310
ASN A 312
LYS A 420
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.39A 1ghmA-3a3iA:
20.6		 1ghmA-3a3iA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
LYS B 397
SER B 449
ASN B 451
LYS B 575
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 ( 3.1A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
 0.49A 1ghmA-3zg8B:
15.4		 1ghmA-3zg8B:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		8 / 12 ALA A  68
SER A  69
LYS A  72
SER A 310
ASN A 312
THR A 401
LYS A 420
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.47A 1i2wA-3a3iA:
20.9		 1i2wA-3a3iA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		7 / 12 SER B 394
LYS B 397
SER B 449
ASN B 451
THR B 561
LYS B 575
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 ( 3.1A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
 0.63A 1i2wA-3zg8B:
16.4		 1i2wA-3zg8B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
LYS A  72
SER A 310
ASN A 312
THR A 401
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-3.4A)
 0.51A 1i2wB-3a3iA:
21.0		 1i2wB-3a3iA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
LYS B 397
SER B 449
ASN B 451
THR B 561
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 ( 3.1A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 3.7A)
 0.67A 1i2wB-3zg8B:
16.6		 1i2wB-3zg8B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 SER A  69
LYS A  72
SER A 310
ASN A 312
THR A 401
LYS A 420
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.52A 1ymxA-3a3iA:
20.7		 1ymxA-3a3iA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		7 / 12 SER B 394
LYS B 397
SER B 449
ASN B 451
THR B 561
LYS B 575
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 ( 3.1A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
 0.66A 1ymxA-3zg8B:
17.4		 1ymxA-3zg8B:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 SER A  69
LYS A  72
SER A 310
ASN A 312
LYS A 420
GLY A 422
SER A 423
 AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.74A 1ymxB-3a3iA:
20.7		 1ymxB-3a3iA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		7 / 12 SER B 394
LYS B 397
SER B 449
ASN B 451
LYS B 575
GLY B 577
SER B 578
 AIX  B 800 (-0.2A)
AIX  B 800 ( 3.1A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
AIX  B 800 (-3.0A)
 0.57A 1ymxB-3zg8B:
17.3		 1ymxB-3zg8B:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 8 SER A 310
THR A 401
ALA A 431
ALA A 419
 AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
None
None
 1.00A 3ax9B-3a3iA:
1.8		 3ax9B-3a3iA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		4 / 5 PRO B 441
THR B 561
VAL B 556
GLY B 560
 None
AIX  B 800 ( 3.8A)
None
None
 1.14A 3elzA-3zg8B:
0.5		 3elzA-3zg8B:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 LYS A  72
SER A 310
ASN A 312
THR A 401
LYS A 420
GLY A 422
 AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.41A 3hlwA-3a3iA:
20.7		 3hlwA-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		7 / 12 LYS B 397
SER B 449
ASN B 451
THR B 561
LYS B 575
GLY B 577
SER B 578
 AIX  B 800 ( 3.1A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
AIX  B 800 (-3.0A)
 0.64A 3hlwA-3zg8B:
17.2		 3hlwA-3zg8B:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A 310
ASN A 312
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.22A 3hlwB-3a3iA:
20.9		 3hlwB-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
SER A 423
 AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.73A 3hlwB-3a3iA:
20.9		 3hlwB-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		7 / 12 SER B 449
ASN B 451
THR B 561
LYS B 575
THR B 576
GLY B 577
SER B 578
 AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
AIX  B 800 (-3.0A)
 0.51A 3hlwB-3zg8B:
17.3		 3hlwB-3zg8B:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LYS A  72
ASN A 312
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 ( 4.0A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.42A 3huoA-3a3iA:
20.7		 3huoA-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 LYS B 397
ASN B 451
LYS B 575
THR B 576
GLY B 577
SER B 578
 AIX  B 800 ( 3.1A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
AIX  B 800 (-3.0A)
 0.61A 3huoA-3zg8B:
17.2		 3huoA-3zg8B:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LYS A  72
ASN A 312
LYS A 420
GLY A 422
SER A 423
 AIX  A 501 ( 4.0A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.92A 3huoB-3a3iA:
20.8		 3huoB-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		5 / 12 LYS B 397
ASN B 451
LYS B 575
GLY B 577
SER B 578
 AIX  B 800 ( 3.1A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
AIX  B 800 (-3.0A)
 0.60A 3huoB-3zg8B:
17.1		 3huoB-3zg8B:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
LYS A  72
ASN A 312
LEU A 362
THR A 421
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-3.3A)
AIX  A 501 (-4.9A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.73A 3mzeA-3a3iA:
18.2		 3mzeA-3a3iA:
22.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3ita D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC
(Escherichia
coli) 		7 / 12 ALA A  39
SER A  40
LYS A  43
GLY A  81
ASN A 108
LEU A 149
GLY A 211
 AIX  A 500 (-3.6A)
AIX  A 500 (-1.4A)
None
None
None
None
AIX  A 500 (-3.4A)
 0.82A 3mzeA-3itaA:
47.1		 3mzeA-3itaA:
63.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3ita D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC
(Escherichia
coli) 		7 / 12 SER A  40
LYS A  43
ASN A 108
LEU A 149
THR A 210
GLY A 211
ARG A 244
 AIX  A 500 (-1.4A)
None
None
None
AIX  A 500 (-4.2A)
AIX  A 500 (-3.4A)
AIX  A 500 (-3.0A)
 0.75A 3mzeA-3itaA:
47.1		 3mzeA-3itaA:
63.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3ita D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC
(Escherichia
coli) 		7 / 12 SER A  40
LYS A  43
GLY A  81
ASN A 108
LEU A 149
THR A 210
GLY A 211
 AIX  A 500 (-1.4A)
None
None
None
None
AIX  A 500 (-4.2A)
AIX  A 500 (-3.4A)
 0.73A 3mzeA-3itaA:
47.1		 3mzeA-3itaA:
63.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
LYS B 397
ASN B 451
THR B 576
GLY B 577
THR B 579
 AIX  B 800 (-0.2A)
AIX  B 800 ( 3.1A)
AIX  B 800 (-2.7A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
GOL  B1643 (-4.3A)
 0.96A 3mzeA-3zg8B:
5.6		 3mzeA-3zg8B:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		4 / 8 SER A 310
THR A 401
ALA A 431
ALA A 419
 AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
None
None
 0.94A 3ns1L-3a3iA:
undetectable		 3ns1L-3a3iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.52A 3ny4A-3a3iA:
19.5		 3ny4A-3a3iA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
SER B 449
THR B 561
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.51A 3ny4A-3zg8B:
16.4		 3ny4A-3zg8B:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LYS A  72
SER A 310
ASN A 312
LYS A 420
GLY A 422
 AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.30A 3q07A-3a3iA:
20.7		 3q07A-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 LYS B 397
SER B 449
ASN B 451
LYS B 575
GLY B 577
SER B 578
 AIX  B 800 ( 3.1A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
AIX  B 800 (-3.0A)
 0.63A 3q07A-3zg8B:
17.3		 3q07A-3zg8B:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 LYS A  72
SER A 310
ASN A 312
LYS A 420
GLY A 422
SER A 423
 AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.81A 3q07B-3a3iA:
20.8		 3q07B-3a3iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 LYS B 397
SER B 449
ASN B 451
LYS B 575
GLY B 577
SER B 578
 AIX  B 800 ( 3.1A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
AIX  B 800 (-3.0A)
 0.68A 3q07B-3zg8B:
17.2		 3q07B-3zg8B:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.21A 3sh8A-3a3iA:
20.9		 3sh8A-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
SER B 449
ASN B 451
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.29A 3sh8A-3zg8B:
16.9		 3sh8A-3zg8B:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
LYS A  72
SER A 310
ASN A 312
LYS A 420
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.29A 3sh8B-3a3iA:
21.0		 3sh8B-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
LYS B 397
SER B 449
ASN B 451
LYS B 575
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 ( 3.1A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
 0.37A 3sh8B-3zg8B:
16.7		 3sh8B-3zg8B:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		5 / 12 ARG B 482
LEU B 488
SER B 394
GLU B 471
ALA B 400
 None
GOL  B1643 (-4.1A)
AIX  B 800 (-0.2A)
None
None
 0.99A 3sxjA-3zg8B:
undetectable		 3sxjA-3zg8B:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		5 / 12 ARG B 482
LEU B 488
SER B 394
GLU B 471
ALA B 400
 None
GOL  B1643 (-4.1A)
AIX  B 800 (-0.2A)
None
None
 1.00A 3sxjB-3zg8B:
undetectable		 3sxjB-3zg8B:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 LYS A  72
SER A 310
ASN A 312
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 ( 4.0A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.62A 4euzA-3a3iA:
19.4		 4euzA-3a3iA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		7 / 12 LYS B 397
SER B 449
ASN B 451
THR B 561
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 ( 3.1A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.71A 4euzA-3zg8B:
16.7		 4euzA-3zg8B:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 10 SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
ALA A  68
 AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.6A)
 1.47A 4fh2A-3a3iA:
21.4		 4fh2A-3a3iA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		5 / 10 SER B 449
ASN B 451
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.61A 4fh2A-3zg8B:
16.6		 4fh2A-3zg8B:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.25A 4n9kA-3a3iA:
21.0		 4n9kA-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
SER B 449
ASN B 451
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.35A 4n9kA-3zg8B:
16.8		 4n9kA-3zg8B:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
ASN A 312
LYS A 420
THR A 421
GLY A 422
TYR A 428
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
None
 0.87A 4n9kB-3a3iA:
21.0		 4n9kB-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 12 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.23A 4n9kB-3a3iA:
21.0		 4n9kB-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
SER B 449
ASN B 451
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.35A 4n9kB-3zg8B:
16.7		 4n9kB-3zg8B:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		3 / 3 THR A 256
ASN A 312
PHE A 167
 None
AIX  A 501 (-3.3A)
AIX  A 501 (-3.6A)
 0.84A 4pd9A-3a3iA:
undetectable		 4pd9A-3a3iA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 ASN A 312
THR A 401
LYS A 420
THR A 421
GLY A 422
SER A 423
 AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.70A 4pm5A-3a3iA:
20.6		 4pm5A-3a3iA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
SER A 423
 AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.91A 4pm5A-3a3iA:
20.6		 4pm5A-3a3iA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		7 / 12 SER B 449
ASN B 451
THR B 561
LYS B 575
THR B 576
GLY B 577
SER B 578
 AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
AIX  B 800 (-3.0A)
 0.72A 4pm5A-3zg8B:
17.5		 4pm5A-3zg8B:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 LYS A  72
ASN A 312
THR A 401
LYS A 420
GLY A 422
 AIX  A 501 ( 4.0A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.45A 4pm7A-3a3iA:
20.6		 4pm7A-3a3iA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 LYS B 397
SER B 449
ASN B 451
THR B 561
LYS B 575
GLY B 577
 AIX  B 800 ( 3.1A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
 0.79A 4pm7A-3zg8B:
17.6		 4pm7A-3zg8B:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 ASN A 312
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.22A 4pm9A-3a3iA:
20.7		 4pm9A-3a3iA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 449
ASN B 451
THR B 561
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.68A 4pm9A-3zg8B:
17.4		 4pm9A-3zg8B:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 ILE A 409
THR A  70
THR A 421
LEU A 408
LEU A 465
 None
None
AIX  A 501 (-3.4A)
None
None
 1.34A 4qynB-3a3iA:
undetectable		 4qynB-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 ILE A 409
THR A  70
THR A 421
LEU A 408
LEU A 465
 None
None
AIX  A 501 (-3.4A)
None
None
 1.34A 4qzuA-3a3iA:
undetectable		 4qzuA-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 ALA A  68
SER A  69
ASN A 312
LYS A 420
GLY A 422
TYR A 428
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
None
 0.96A 5ghyA-3a3iA:
20.8		 5ghyA-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.22A 5ghyA-3a3iA:
20.8		 5ghyA-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		5 / 12 SER B 394
SER B 449
ASN B 451
LYS B 575
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
 0.32A 5ghyA-3zg8B:
16.7		 5ghyA-3zg8B:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.19A 5ghyB-3a3iA:
20.7		 5ghyB-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		5 / 12 SER B 394
SER B 449
ASN B 451
LYS B 575
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
 0.31A 5ghyB-3zg8B:
16.5		 5ghyB-3zg8B:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 11 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.24A 5ghzA-3a3iA:
21.0		 5ghzA-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 11 SER B 394
SER B 449
ASN B 451
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.32A 5ghzA-3zg8B:
16.7		 5ghzA-3zg8B:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		7 / 10 ALA A  68
SER A  69
SER A 310
ASN A 312
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-3.6A)
AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.23A 5ghzB-3a3iA:
20.9		 5ghzB-3a3iA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 10 SER B 394
SER B 449
ASN B 451
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.31A 5ghzB-3zg8B:
16.8		 5ghzB-3zg8B:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		4 / 5 GLY B 393
PRO B 497
THR B 395
THR B 579
 AIX  B 800 (-3.9A)
None
None
GOL  B1643 (-4.3A)
 1.29A 5h5fA-3zg8B:
undetectable		 5h5fA-3zg8B:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		4 / 7 SER B 394
PRO B 398
TYR B 504
SER B 623
 AIX  B 800 (-0.2A)
None
None
AIX  B 800 (-2.4A)
 1.20A 5l1fC-3zg8B:
undetectable		 5l1fC-3zg8B:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.44A 6b5yB-3a3iA:
20.2		 6b5yB-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
SER B 449
THR B 561
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.42A 6b5yB-3zg8B:
16.4		 6b5yB-3zg8B:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.50A 6b5yD-3a3iA:
20.1		 6b5yD-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
SER B 449
THR B 561
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.49A 6b5yD-3zg8B:
16.4		 6b5yD-3zg8B:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.27A 6b68B-3a3iA:
20.1		 6b68B-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
SER B 449
THR B 561
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.30A 6b68B-3zg8B:
16.3		 6b68B-3zg8B:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
 0.37A 6b68D-3a3iA:
20.1		 6b68D-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		5 / 12 SER B 394
SER B 449
THR B 561
LYS B 575
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
 0.41A 6b68D-3zg8B:
16.4		 6b68D-3zg8B:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.25A 6b69A-3a3iA:
20.0
6b69B-3a3iA:
19.9		 6b69A-3a3iA:
12.53
6b69B-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
SER B 449
THR B 561
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.31A 6b69A-3zg8B:
16.3
6b69B-3zg8B:
16.4		 6b69A-3zg8B:
9.30
6b69B-3zg8B:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.25A 6b69D-3a3iA:
20.1		 6b69D-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
SER B 449
THR B 561
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.31A 6b69D-3zg8B:
16.3		 6b69D-3zg8B:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.30A 6b6aB-3a3iA:
20.2		 6b6aB-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
SER B 449
THR B 561
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.33A 6b6aB-3zg8B:
16.6		 6b6aB-3zg8B:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 SER A  69
SER A 310
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.23A 6b6aD-3a3iA:
20.2		 6b6aD-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		5 / 12 SER B 394
SER B 449
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.31A 6b6aD-3zg8B:
16.5		 6b6aD-3zg8B:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 SER A  69
SER A 310
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.40A 6b6cA-3a3iA:
19.8		 6b6cA-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.60A 6b6dA-3a3iA:
20.0		 6b6dA-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
SER B 449
THR B 561
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.60A 6b6dA-3zg8B:
16.6		 6b6dA-3zg8B:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A  69
SER A 310
THR A 401
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.33A 6b6eA-3a3iA:
20.0		 6b6eA-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 394
SER B 449
THR B 561
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.39A 6b6eA-3zg8B:
16.5		 6b6eA-3zg8B:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		5 / 12 SER A  69
SER A 310
LYS A 420
THR A 421
GLY A 422
 AIX  A 501 (-1.3A)
AIX  A 501 (-2.8A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-3.4A)
 0.53A 6b6fA-3a3iA:
19.5		 6b6fA-3a3iA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		5 / 12 SER B 394
SER B 449
LYS B 575
THR B 576
GLY B 577
 AIX  B 800 (-0.2A)
AIX  B 800 (-2.4A)
AIX  B 800 ( 4.0A)
AIX  B 800 (-3.4A)
AIX  B 800 ( 3.7A)
 0.60A 6b6fA-3zg8B:
16.5		 6b6fA-3zg8B:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 3a3i PENICILLIN-BINDING
PROTEIN 4
(Haemophilus
influenzae) 		6 / 12 SER A 310
ASN A 312
THR A 401
LYS A 420
GLY A 422
SER A 423
 AIX  A 501 (-2.8A)
AIX  A 501 (-3.3A)
AIX  A 501 ( 4.0A)
AIX  A 501 ( 3.8A)
AIX  A 501 (-3.4A)
AIX  A 501 (-2.5A)
 0.67A 6c79A-3a3iA:
20.5		 6c79A-3a3iA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 3zg8 PENICILLIN-BINDING
PROTEIN 4
(Listeria
monocytogenes) 		6 / 12 SER B 449
ASN B 451
THR B 561
LYS B 575
GLY B 577
SER B 578
 AIX  B 800 (-2.4A)
AIX  B 800 (-2.7A)
AIX  B 800 ( 3.8A)
AIX  B 800 ( 4.0A)
AIX  B 800 ( 3.7A)
AIX  B 800 (-3.0A)
 0.47A 6c79A-3zg8B:
17.5		 6c79A-3zg8B:
9.56