SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AHR'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		5 / 12 LEU A  73
ALA A  55
ALA A  41
THR A 265
VAL A 297
 None
None
None
AHR  A 338 ( 4.8A)
None
 1.23A 1cbrA-3qefA:
undetectable		 1cbrA-3qefA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		5 / 12 LEU A  73
ALA A  55
ALA A  41
THR A 265
VAL A 297
 None
None
None
AHR  A 338 ( 4.8A)
None
 1.23A 1cbrB-3qefA:
undetectable		 1cbrB-3qefA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 5ocp -
(-) 		4 / 8 LEU A 131
ARG A 143
PHE A 147
GLY A 111
 None
AHR  A 407 ( 2.6A)
None
None
 0.93A 1fapB-5ocpA:
undetectable		 1fapB-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 HIS A 412
GLY A 394
ASN A 396
GLY A 305
ASP A 238
 None
None
None
None
AHR  A 720 ( 4.9A)
 1.29A 1ffyA-5ho9A:
undetectable		 1ffyA-5ho9A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_A_DAHA382_1
(AMINE OXIDASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 10 THR A 343
ASN A 266
TYR A 344
HIS A  93
HIS A  89
 None
AHR  A 901 (-3.7A)
None
None
None
 1.35A 1ivvA-5opjA:
undetectable		 1ivvA-5opjA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ocp -
(-) 		3 / 3 ARG A 143
VAL A 225
TRP A  14
 AHR  A 407 ( 2.6A)
None
AHR  A 407 ( 4.8A)
 0.90A 1qw6A-5ocpA:
undetectable		 1qw6A-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ocp -
(-) 		3 / 3 ARG A 143
VAL A 225
TRP A  14
 AHR  A 407 ( 2.6A)
None
AHR  A 407 ( 4.8A)
 0.94A 1qwcA-5ocpA:
undetectable		 1qwcA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 326
HIS A 412
THR A 322
ASP A 238
GLY A  69
 None
None
None
AHR  A 720 ( 4.9A)
None
 1.18A 1v8bA-5ho9A:
undetectable		 1v8bA-5ho9A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 326
HIS A 412
THR A 322
ASP A 238
GLY A  69
 None
None
None
AHR  A 720 ( 4.9A)
None
 1.16A 1v8bB-5ho9A:
undetectable		 1v8bB-5ho9A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 326
HIS A 412
THR A 322
ASP A 238
GLY A  69
 None
None
None
AHR  A 720 ( 4.9A)
None
 1.20A 1v8bD-5ho9A:
undetectable		 1v8bD-5ho9A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ocp -
(-) 		3 / 3 ARG A 143
VAL A 225
TRP A  14
 AHR  A 407 ( 2.6A)
None
AHR  A 407 ( 4.8A)
 0.88A 1vagA-5ocpA:
undetectable		 1vagA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 2w5o ALPHA-L-ARABINOFURAN
OSIDASE
(Fusarium
graminearum) 		4 / 5 ALA A 356
TYR A  44
ALA A 336
TYR A 337
 None
AHR  A 501 ( 4.8A)
None
None
 1.06A 1xl6A-2w5oA:
undetectable
1xl6B-2w5oA:
undetectable		 1xl6A-2w5oA:
19.78
1xl6B-2w5oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ocp -
(-) 		3 / 3 ARG A 143
VAL A 225
TRP A  14
 AHR  A 407 ( 2.6A)
None
AHR  A 407 ( 4.8A)
 0.87A 1zviA-5ocpA:
undetectable		 1zviA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 2w5o ALPHA-L-ARABINOFURAN
OSIDASE
(Fusarium
graminearum) 		4 / 4 ALA A 356
TYR A  44
ALA A 336
TYR A 337
 None
AHR  A 501 ( 4.8A)
None
None
 1.02A 2wlkA-2w5oA:
undetectable
2wlkB-2w5oA:
undetectable		 2wlkA-2w5oA:
19.78
2wlkB-2w5oA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 326
HIS A 412
GLU A 304
ASP A 238
GLY A  69
 None
None
AHR  A 721 ( 3.8A)
AHR  A 720 ( 4.9A)
None
 1.36A 2zj0A-5ho9A:
undetectable		 2zj0A-5ho9A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 4n2r ALPHA-L-ARABINOFURAN
OSIDASE UMABF62A
(Ustilago
maydis) 		4 / 7 GLU A 195
GLU A 213
TYR A 296
SER A 260
 AHR  A 403 (-2.8A)
None
None
None
 1.10A 2zt7A-4n2rA:
undetectable		 2zt7A-4n2rA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 4n2r ALPHA-L-ARABINOFURAN
OSIDASE UMABF62A
(Ustilago
maydis) 		5 / 10 PHE A 157
ALA A  86
PHE A 109
LEU A 129
THR A  88
 None
AHR  A 403 ( 3.9A)
None
None
None
 1.25A 3a3yA-4n2rA:
undetectable		 3a3yA-4n2rA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 4o8o ALPHA-L-ARABINOFURAN
OSIDASE
(Streptomyces
thermoviolaceus) 		5 / 10 PHE A 210
ALA A 139
PHE A 162
LEU A 182
THR A 141
 None
AHR  A 402 ( 3.7A)
None
None
None
 1.20A 3a3yA-4o8oA:
undetectable		 3a3yA-4o8oA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 326
HIS A 412
GLU A 304
ASP A 238
GLY A  69
 None
None
AHR  A 721 ( 3.8A)
AHR  A 720 ( 4.9A)
None
 1.36A 3ce6A-5ho9A:
undetectable		 3ce6A-5ho9A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 326
HIS A 412
GLU A 304
ASP A 238
GLY A  69
 None
None
AHR  A 721 ( 3.8A)
AHR  A 720 ( 4.9A)
None
 1.38A 3ce6C-5ho9A:
undetectable		 3ce6C-5ho9A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 HIS A 412
GLU A 304
THR A 322
ASP A 238
GLY A  69
 None
AHR  A 721 ( 3.8A)
None
AHR  A 720 ( 4.9A)
None
 1.38A 3ce6D-5ho9A:
undetectable		 3ce6D-5ho9A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 326
HIS A 412
THR A 322
ASP A 238
GLY A  69
 None
None
None
AHR  A 720 ( 4.9A)
None
 1.23A 3g1uD-5ho9A:
undetectable		 3g1uD-5ho9A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 320
GLU A 339
TRP A  81
 AHR  A 901 (-2.7A)
AHR  A 901 ( 2.7A)
None
 1.11A 3hrdA-5opjA:
undetectable
3hrdE-5opjA:
undetectable
3hrdF-5opjA:
undetectable		 3hrdA-5opjA:
12.40
3hrdE-5opjA:
12.40
3hrdF-5opjA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 4n2r ALPHA-L-ARABINOFURAN
OSIDASE UMABF62A
(Ustilago
maydis) 		5 / 12 GLY A 140
GLY A 138
GLU A 195
ALA A 159
TYR A 165
 None
None
AHR  A 403 (-2.8A)
None
None
 1.18A 3t7sC-4n2rA:
undetectable		 3t7sC-4n2rA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		4 / 6 THR A 214
ASN A 185
GLY A 184
ASP A 168
 AHR  A 337 (-4.7A)
AHR  A 338 ( 3.2A)
None
None
 1.17A 3w9tE-3qefA:
undetectable		 3w9tE-3qefA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5ocp -
(-) 		5 / 12 PHE A 107
ILE A  86
GLU A 110
GLU A  11
PHE A  18
 None
None
None
AHR  A 407 ( 3.5A)
None
 1.40A 4a97A-5ocpA:
undetectable
4a97B-5ocpA:
undetectable		 4a97A-5ocpA:
undetectable
4a97B-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5ocp -
(-) 		3 / 3 ASP A  88
ARG A  89
ASP A 223
 AHR  A 407 ( 2.6A)
FUB  A 408 ( 3.9A)
AHR  A 407 ( 2.8A)
 0.87A 4fzvA-5ocpA:
undetectable		 4fzvA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2w5o ALPHA-L-ARABINOFURAN
OSIDASE
(Fusarium
graminearum) 		3 / 3 LEU A 359
PRO A 360
ARG A 223
 None
None
AHR  A 500 (-3.9A)
 0.62A 4klrB-2w5oA:
undetectable		 4klrB-2w5oA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		4 / 6 THR A 214
THR A 263
HIS A 282
ASN A 257
 AHR  A 337 (-4.7A)
None
None
None
 1.27A 4pfjB-3qefA:
undetectable		 4pfjB-3qefA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		4 / 5 THR A 214
THR A 263
HIS A 282
ASN A 257
 AHR  A 337 (-4.7A)
None
None
None
 1.30A 4pgfB-3qefA:
undetectable		 4pgfB-3qefA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 575
VAL A 406
GLN A 689
GLU A 320
HIS A 585
 None
None
AHR  A 901 (-3.6A)
AHR  A 901 (-2.7A)
None
 1.42A 4zj8A-5opjA:
undetectable		 4zj8A-5opjA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 258
THR A 304
ASN A 316
VAL A 311
HIS A 264
 None
None
None
None
AHR  A 901 (-3.9A)
 1.45A 5d0yA-5opjA:
undetectable		 5d0yA-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_B_FOLB201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5opj RHAMNOGALACTURONAN
LYASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASP A 258
THR A 304
ASN A 316
VAL A 311
HIS A 264
 None
None
None
None
AHR  A 901 (-3.9A)
 1.46A 5d0yB-5opjA:
undetectable		 5d0yB-5opjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 326
GLU A 304
THR A 322
ASP A 238
GLY A  69
 None
AHR  A 721 ( 3.8A)
None
AHR  A 720 ( 4.9A)
None
 1.02A 5m5kB-5ho9A:
undetectable		 5m5kB-5ho9A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 326
HIS A 412
THR A 322
ASP A 238
GLY A  69
 None
None
None
AHR  A 720 ( 4.9A)
None
 1.13A 5m5kB-5ho9A:
undetectable		 5m5kB-5ho9A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 326
HIS A 412
THR A 322
ASP A 238
GLY A  69
 None
None
None
AHR  A 720 ( 4.9A)
None
 1.15A 5m66A-5ho9A:
undetectable		 5m66A-5ho9A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		3 / 3 GLU A  73
HIS A  54
VAL A  53
 AHR  A 718 ( 3.0A)
AHR  A 719 ( 3.7A)
None
 0.93A 5trqB-5ho9A:
undetectable		 5trqB-5ho9A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 326
HIS A 412
THR A 322
ASP A 238
GLY A  69
 None
None
None
AHR  A 720 ( 4.9A)
None
 1.19A 5utuF-5ho9A:
undetectable		 5utuF-5ho9A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5ocp -
(-) 		3 / 3 ASP A  88
ARG A  89
ASP A 223
 AHR  A 407 ( 2.6A)
FUB  A 408 ( 3.9A)
AHR  A 407 ( 2.8A)
 0.85A 5zvgA-5ocpA:
undetectable		 5zvgA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5ocp -
(-) 		3 / 3 ASP A  88
ARG A  89
ASP A 223
 AHR  A 407 ( 2.6A)
FUB  A 408 ( 3.9A)
AHR  A 407 ( 2.8A)
 0.88A 5zvgB-5ocpA:
2.2		 5zvgB-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		4 / 6 TYR A 244
GLU A 292
ASP A 291
CYH A 169
 None
AHR  A 600 (-2.8A)
None
None
 1.49A 6mn5A-5o82A:
undetectable		 6mn5A-5o82A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		4 / 6 TYR A 244
GLU A 292
ASP A 291
CYH A 169
 None
AHR  A 600 (-2.8A)
None
None
 1.44A 6mn5C-5o82A:
undetectable		 6mn5C-5o82A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 5ho9 EXTRACELLULAR
ARABINANASE
(Geobacillus
stearothermophil
us) 		4 / 7 GLY A 305
HIS A 422
GLU A  73
GLY A  69
 None
AHR  A 718 ( 4.3A)
AHR  A 718 ( 3.0A)
None
 0.98A 6n7fA-5ho9A:
undetectable		 6n7fA-5ho9A:
9.49