SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AGT'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		4 / 7 ASP A  96
TRP A 119
TYR A 127
ARG A  34
 AGT  A 357 ( 3.3A)
AGT  A 357 ( 3.9A)
None
None
 1.44A 1cebB-2jerA:
undetectable		 1cebB-2jerA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 7 ASP A  94
TRP A 125
TYR A 133
ARG A  32
 AGT  A 366 ( 3.0A)
AGT  A 366 (-3.9A)
None
None
 1.47A 1cebB-3h7kA:
undetectable		 1cebB-3h7kA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		3 / 3 ASP A 226
VAL A 168
PRO A  16
 AGT  A 366 ( 2.2A)
None
None
 0.74A 2avvA-3h7kA:
undetectable		 2avvA-3h7kA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 12 THR A 221
GLY A 223
GLY A 217
VAL A 176
HIS A 224
 AGT  A 366 ( 4.5A)
None
NA  A 387 (-3.7A)
None
AGT  A 366 ( 4.1A)
 1.16A 2b25B-3h7kA:
undetectable		 2b25B-3h7kA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 6 LEU A 203
ILE A 118
ARG A  93
GLY A 164
 None
None
None
AGT  A 366 ( 3.5A)
 0.82A 2du8A-3h7kA:
undetectable		 2du8A-3h7kA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 6 LEU A 203
ILE A 118
ARG A  93
GLY A 164
 None
None
None
AGT  A 366 ( 3.5A)
 0.79A 2du8B-3h7kA:
undetectable		 2du8B-3h7kA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		5 / 11 SER A 178
THR A 215
GLY A 217
HIS A 218
PHE A 161
 None
AGT  A 357 ( 4.3A)
None
None
None
 1.48A 2hmaA-2jerA:
undetectable		 2hmaA-2jerA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		5 / 12 ASN A 354
ASN A  37
VAL A  52
ALA A  53
VAL A  94
 None
AGT  A 357 ( 4.6A)
None
None
None
 1.27A 2nniA-2jerA:
undetectable		 2nniA-2jerA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 12 ASN A 123
GLY A 131
GLY A 127
TYR A 133
ASN A  35
 None
NA  A 385 ( 4.5A)
None
None
AGT  A 366 ( 4.8A)
 1.23A 2zw9A-3h7kA:
undetectable		 2zw9A-3h7kA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		4 / 6 GLY A 351
GLU A 214
GLY A 353
ASN A  37
 None
AGT  A 357 ( 3.8A)
AGT  A 357 ( 3.8A)
AGT  A 357 ( 4.6A)
 0.93A 3e9rA-2jerA:
undetectable		 3e9rA-2jerA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		4 / 6 GLY A 351
GLU A 214
GLY A 353
ASN A  37
 None
AGT  A 357 ( 3.8A)
AGT  A 357 ( 3.8A)
AGT  A 357 ( 4.6A)
 0.94A 3e9rC-2jerA:
undetectable		 3e9rC-2jerA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		5 / 12 ASP A 221
ASP A 220
VAL A 314
ALA A 327
ILE A 355
 AGT  A 357 ( 4.9A)
AGT  A 357 ( 3.8A)
None
None
None
 1.19A 3n3iA-2jerA:
undetectable		 3n3iA-2jerA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		3 / 3 GLY A 164
ASP A  94
ASP A  89
 AGT  A 366 ( 3.5A)
AGT  A 366 ( 3.0A)
None
 0.47A 3ou7C-3h7kA:
undetectable		 3ou7C-3h7kA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		4 / 8 ASP A 124
ASP A  96
ASN A 216
CYH A 175
 None
AGT  A 357 ( 3.3A)
None
None
 1.10A 4feuF-2jerA:
undetectable		 4feuF-2jerA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		4 / 8 ASP A 124
ASP A  96
ASN A 216
CYH A 175
 None
AGT  A 357 ( 3.3A)
None
None
 1.10A 4fewD-2jerA:
undetectable		 4fewD-2jerA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		4 / 8 ASP A 124
ASP A  96
ASN A 216
CYH A 175
 None
AGT  A 357 ( 3.3A)
None
None
 1.13A 4fewF-2jerA:
undetectable		 4fewF-2jerA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		4 / 8 ASP A 124
ASP A  96
ASN A 216
CYH A 175
 None
AGT  A 357 ( 3.3A)
None
None
 1.11A 4gkhB-2jerA:
undetectable		 4gkhB-2jerA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 8 ASP A  94
CYH A 180
GLU A 179
ASP A 226
 AGT  A 366 ( 3.0A)
None
None
AGT  A 366 ( 2.2A)
 1.05A 4gkhB-3h7kA:
undetectable		 4gkhB-3h7kA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 8 ASP A  94
CYH A 180
GLU A 179
ASP A 226
 AGT  A 366 ( 3.0A)
None
None
AGT  A 366 ( 2.2A)
 0.90A 4gkhD-3h7kA:
undetectable		 4gkhD-3h7kA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		4 / 8 ASP A 124
ASP A  96
ASN A 216
CYH A 175
 None
AGT  A 357 ( 3.3A)
None
None
 1.11A 4gkiA-2jerA:
undetectable		 4gkiA-2jerA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		4 / 8 ASP A 124
ASP A  96
ASN A 216
CYH A 175
 None
AGT  A 357 ( 3.3A)
None
None
 1.11A 4gkiC-2jerA:
undetectable		 4gkiC-2jerA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 8 ASP A  94
CYH A 180
GLU A 179
ASP A 226
 AGT  A 366 ( 3.0A)
None
None
AGT  A 366 ( 2.2A)
 1.02A 4gkiC-3h7kA:
undetectable		 4gkiC-3h7kA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 6 LEU A 339
HIS A 365
HIS A 167
GLU A  18
 None
AGT  A 366 ( 4.8A)
None
None
 1.06A 4pahA-3h7kA:
undetectable		 4pahA-3h7kA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 8 HIS A  22
ASN A 318
HIS A 365
THR A 368
 None
None
AGT  A 366 ( 4.8A)
None
 1.31A 5db5A-3h7kA:
undetectable
5db5B-3h7kA:
undetectable		 5db5A-3h7kA:
21.59
5db5B-3h7kA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		4 / 8 PRO A 317
TYR A 319
VAL A 349
GLY A 353
 None
None
None
AGT  A 357 ( 3.8A)
 0.86A 5nzyA-2jerA:
undetectable		 5nzyA-2jerA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B2W_A_AG2A401_1
(PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		6 / 10 ASP A  91
TRP A  93
ASP A  96
TRP A 119
THR A 215
HIS A 218
 None
AGT  A 357 ( 3.4A)
AGT  A 357 ( 3.3A)
AGT  A 357 ( 3.9A)
AGT  A 357 ( 4.3A)
None
 0.55A 6b2wA-2jerA:
43.7		 6b2wA-2jerA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B2W_A_AG2A401_1
(PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN)		 2jer AGMATINE DEIMINASE
(Enterococcus
faecalis) 		5 / 10 ASP A 133
ASP A  96
TRP A 119
THR A 215
HIS A 218
 None
AGT  A 357 ( 3.3A)
AGT  A 357 ( 3.9A)
AGT  A 357 ( 4.3A)
None
 1.35A 6b2wA-2jerA:
43.7		 6b2wA-2jerA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B2W_A_AG2A401_1
(PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		7 / 10 ASP A  89
TRP A  91
ASP A  94
TRP A 125
ASP A 220
THR A 221
HIS A 224
 None
AGT  A 366 ( 3.6A)
AGT  A 366 ( 3.0A)
AGT  A 366 (-3.9A)
AGT  A 366 (-3.7A)
AGT  A 366 ( 4.5A)
AGT  A 366 ( 4.1A)
 0.76A 6b2wA-3h7kA:
44.9		 6b2wA-3h7kA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B2W_A_AG2A401_1
(PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 10 ASP A 139
ASP A  94
TRP A 125
THR A 221
HIS A 224
 None
AGT  A 366 ( 3.0A)
AGT  A 366 (-3.9A)
AGT  A 366 ( 4.5A)
AGT  A 366 ( 4.1A)
 1.43A 6b2wA-3h7kA:
44.9		 6b2wA-3h7kA:
14.01