SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AFO'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q72_A_IXXA801_1 (TRANSPORTER)	3pty	ARABINOSYLTRANSFERAS E C (Mycobacterium tuberculosis)	5 / 11	LEU A 744 VAL A 736 LEU A1049 ASP A1052 ASP A1051	None AFO A 1 ( 4.9A) None None AFO A 1 (-4.7A)	1.17A	2q72A-3ptyA: undetectable	2q72A-3ptyA: 23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QB4_A_DSMA801_1 (TRANSPORTER)	3pty	ARABINOSYLTRANSFERAS E C (Mycobacterium tuberculosis)	5 / 12	LEU A 744 VAL A 736 LEU A1049 ASP A1052 ASP A1051	None AFO A 1 ( 4.9A) None None AFO A 1 (-4.7A)	1.15A	2qb4A-3ptyA: undetectable	2qb4A-3ptyA: 23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEI_A_CXXA801_1 (TRANSPORTER)	3pty	ARABINOSYLTRANSFERAS E C (Mycobacterium tuberculosis)	5 / 11	LEU A 744 VAL A 736 LEU A1049 ASP A1052 ASP A1051	None AFO A 1 ( 4.9A) None None AFO A 1 (-4.7A)	1.16A	2qeiA-3ptyA: undetectable	2qeiA-3ptyA: 23.12