SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AD0'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2uvf EXOPOLYGALACTURONASE
(Yersinia
enterocolitica) 		3 / 3 ILE A 448
PHE A 519
HIS A 443
 None
None
AD0  A1617 (-3.8A)
 0.70A 3h0aA-2uvfA:
undetectable		 3h0aA-2uvfA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2uvf EXOPOLYGALACTURONASE
(Yersinia
enterocolitica) 		6 / 12 GLN A 418
TYR A 510
GLY A 410
GLY A 386
ALA A 408
SER A 332
 None
None
None
None
AD0  A1617 ( 3.8A)
None
 1.42A 3sudB-2uvfA:
undetectable		 3sudB-2uvfA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 2uvf EXOPOLYGALACTURONASE
(Yersinia
enterocolitica) 		4 / 7 HIS A 443
LEU A 232
GLY A 412
ALA A 415
 AD0  A1617 (-3.8A)
AD0  A1617 (-4.7A)
None
None
 0.94A 3tehB-2uvfA:
undetectable		 3tehB-2uvfA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 2uvf EXOPOLYGALACTURONASE
(Yersinia
enterocolitica) 		4 / 7 PHE A 385
ILE A 405
GLY A 441
PHE A 407
 None
None
AD0  A1617 (-4.6A)
None
 0.77A 5h3aA-2uvfA:
undetectable		 5h3aA-2uvfA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 2uvf EXOPOLYGALACTURONASE
(Yersinia
enterocolitica) 		5 / 12 ARG A 330
GLY A 441
SER A 442
GLY A 380
HIS A 435
 None
AD0  A1617 (-4.6A)
AD0  A1617 (-3.4A)
None
NI  A1614 ( 3.4A)
 0.97A 5hikA-2uvfA:
undetectable		 5hikA-2uvfA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 2uvf EXOPOLYGALACTURONASE
(Yersinia
enterocolitica) 		4 / 5 HIS A 372
MET A 334
ASN A 406
LEU A 333
 None
None
AD0  A1617 (-3.0A)
None
 1.38A 5xdhB-2uvfA:
0.0		 5xdhB-2uvfA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 2uvf EXOPOLYGALACTURONASE
(Yersinia
enterocolitica) 		4 / 6 HIS A 372
MET A 334
ASN A 406
LEU A 333
 None
None
AD0  A1617 (-3.0A)
None
 1.33A 5xdhA-2uvfA:
undetectable
5xdhC-2uvfA:
undetectable		 5xdhA-2uvfA:
9.52
5xdhC-2uvfA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 2uvf EXOPOLYGALACTURONASE
(Yersinia
enterocolitica) 		4 / 5 HIS A 372
MET A 334
ASN A 406
LEU A 333
 None
None
AD0  A1617 (-3.0A)
None
 1.46A 5xdhD-2uvfA:
undetectable		 5xdhD-2uvfA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 2uvf EXOPOLYGALACTURONASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 380
GLY A 434
ASN A 351
ASP A 402
PHE A 354
 None
None
None
AD0  A1617 (-3.1A)
AD0  A1617 ( 4.9A)
 1.32A 5yn6A-2uvfA:
undetectable		 5yn6A-2uvfA:
20.40