SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AC1'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 TYR A  62
LEU A 162
LEU A 165
ASP A 197
ALA A 198
HIS A 299
ASP A 300
 AC1  A 992 ( 3.6A)
None
AC1  A 990 ( 4.8A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.61A 1dedA-1oseA:
27.3		 1dedA-1oseA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		6 / 12 TYR A  58
LEU A 201
ASP A 236
ALA A 237
HIS A 332
ASP A 333
 AC1  A1492 ( 3.9A)
AC1  A1492 ( 4.9A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.66A 1dedA-1w9xA:
25.7		 1dedA-1w9xA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		8 / 12 TYR A  62
LEU A 165
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 AC1  A 992 ( 3.6A)
AC1  A 990 ( 4.8A)
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.70A 1dedB-1oseA:
24.9		 1dedB-1oseA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 TYR A  58
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 3.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.65A 1dedB-1w9xA:
27.7		 1dedB-1w9xA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 12 TYR A  62
GLN A  63
HIS A 201
GLU A 233
HIS A 299
 AC1  A 992 ( 3.6A)
GLC  A 991 ( 3.7A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
 1.14A 1eswA-1oseA:
14.1		 1eswA-1oseA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 12 TYR A  62
GLN A  63
HIS A 299
ASP A 300
TRP A  58
 AC1  A 992 ( 3.6A)
GLC  A 991 ( 3.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
None
 1.01A 1eswA-1oseA:
14.1		 1eswA-1oseA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 12 TYR A  58
HIS A 240
HIS A 332
ASP A 333
TRP A  15
 AC1  A1492 ( 3.9A)
AC1  A1492 ( 3.9A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
None
 1.27A 1eswA-1w9xA:
15.2		 1eswA-1w9xA:
21.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		10 / 12 TRP A  58
GLN A  63
HIS A 101
VAL A 163
GLY A 164
ALA A 198
GLU A 233
ILE A 235
ASP A 300
HIS A 305
 None
GLC  A 991 ( 3.7A)
AC1  A 992 ( 3.7A)
AC1  A 990 (-4.3A)
AC1  A 990 (-3.5A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
BGC  A 993 (-3.9A)
AC1  A 992 (-3.0A)
GLC  A 991 ( 4.0A)
 0.46A 1kxhA-1oseA:
50.9		 1kxhA-1oseA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 TRP A  58
HIS A 101
GLY A 104
GLU A 233
ASP A 300
HIS A 305
 None
AC1  A 992 ( 3.7A)
AC1  A 990 ( 3.8A)
AC1  A 992 ( 2.7A)
AC1  A 992 (-3.0A)
GLC  A 991 ( 4.0A)
 1.21A 1kxhA-1oseA:
50.9		 1kxhA-1oseA:
47.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 12 TRP A  15
HIS A 107
ALA A 237
GLU A 266
ASP A 333
 None
AC1  A1492 (-4.3A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 ( 3.0A)
 0.70A 1kxhA-1w9xA:
28.3		 1kxhA-1w9xA:
24.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		3 / 3 TRP A  59
TYR A  62
LEU A 165
 AC1  A 990 ( 3.9A)
AC1  A 992 ( 3.6A)
AC1  A 990 ( 4.8A)
 0.23A 1kxhA-1oseA:
50.9		 1kxhA-1oseA:
47.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		9 / 12 TRP A  58
TYR A  62
HIS A 101
ARG A 195
ASP A 197
LYS A 200
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.6A)
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.71A 1mxdA-1oseA:
28.9		 1mxdA-1oseA:
22.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		9 / 12 TRP A  15
TYR A  58
ARG A 234
ASP A 236
LYS A 239
GLU A 266
TRP A 268
HIS A 332
ASP A 333
 None
AC1  A1492 ( 3.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
GLC  A1491 (-2.5A)
AC1  A1492 (-2.8A)
None
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.81A 1mxdA-1w9xA:
39.1		 1mxdA-1w9xA:
32.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		9 / 12 TRP A  15
TYR A  58
HIS A 107
ARG A 234
ASP A 236
LYS A 239
GLU A 266
HIS A 332
ASP A 333
 None
AC1  A1492 ( 3.9A)
AC1  A1492 (-4.3A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
GLC  A1491 (-2.5A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.33A 1mxdA-1w9xA:
39.1		 1mxdA-1w9xA:
32.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 11 TYR A  62
GLN A  63
ASP A 197
HIS A 299
ASP A 300
TRP A  58
 AC1  A 992 ( 3.6A)
GLC  A 991 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
None
 0.97A 2owcA-1oseA:
13.4		 2owcA-1oseA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 11 TYR A  58
ASP A 236
HIS A 332
ASP A 333
TRP A  15
 AC1  A1492 ( 3.9A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
None
 0.96A 2owcA-1w9xA:
14.9		 2owcA-1w9xA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 11 TYR A  62
GLN A  63
ASP A 197
HIS A 299
ASP A 300
TRP A  58
 AC1  A 992 ( 3.6A)
GLC  A 991 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
None
 0.97A 2owwA-1oseA:
13.4		 2owwA-1oseA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 11 TYR A  58
ASP A 236
HIS A 332
ASP A 333
TRP A  15
 AC1  A1492 ( 3.9A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
None
 0.98A 2owwA-1w9xA:
14.8		 2owwA-1w9xA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.61A 3aicA-1oseA:
4.8		 3aicA-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.62A 3aicA-1w9xA:
11.6		 3aicA-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.62A 3aicB-1oseA:
4.9		 3aicB-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.59A 3aicB-1w9xA:
11.5		 3aicB-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
TYR A  62
 AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
AC1  A 992 ( 3.6A)
 0.69A 3aicC-1oseA:
4.3		 3aicC-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
TYR A  58
 AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
AC1  A1492 ( 3.9A)
 0.60A 3aicC-1w9xA:
11.7		 3aicC-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.66A 3aicD-1oseA:
7.5		 3aicD-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.65A 3aicD-1w9xA:
11.7		 3aicD-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.64A 3aicE-1oseA:
3.0		 3aicE-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.64A 3aicE-1w9xA:
11.7		 3aicE-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.63A 3aicF-1oseA:
10.5		 3aicF-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.62A 3aicF-1w9xA:
11.6		 3aicF-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.60A 3aicG-1oseA:
11.0		 3aicG-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.58A 3aicG-1w9xA:
11.7		 3aicG-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.67A 3aicH-1oseA:
4.3		 3aicH-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 LEU A 201
ARG A 234
ASP A 236
ALA A 237
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 ( 4.9A)
AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-3.8A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.68A 3aicH-1w9xA:
11.7		 3aicH-1w9xA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 7 TYR A 342
ILE A 367
GLY A 359
TYR A  62
 None
None
None
AC1  A 992 ( 3.6A)
 0.93A 3elzA-1oseA:
undetectable		 3elzA-1oseA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 8 VAL A 210
LEU A 170
ASP A 197
ILE A 196
 None
None
AC1  A 992 ( 3.3A)
None
 0.84A 4lzrA-1oseA:
undetectable		 4lzrA-1oseA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 12 ARG A 195
ASP A 197
GLU A 233
HIS A 299
ASP A 300
 AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.36A 5csyB-1oseA:
5.1		 5csyB-1oseA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		5 / 12 ARG A 234
ASP A 236
GLU A 266
HIS A 332
ASP A 333
 AC1  A1492 (-3.3A)
AC1  A1492 (-3.0A)
AC1  A1492 (-2.8A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.50A 5csyB-1w9xA:
5.0		 5csyB-1w9xA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 8 VAL A 234
ASP A 236
HIS A 201
GLN A 243
 None
None
AC1  A 992 ( 3.8A)
None
 0.84A 5w3jB-1oseA:
undetectable		 5w3jB-1oseA:
21.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 7 LYS A  72
GLY A 110
TRP A 140
ASP A 166
TRP A 167
MET A 202
TYR A 203
 AC1  A1496 (-2.9A)
AC1  A1496 (-3.4A)
AC1  A1496 (-3.7A)
GLC  A1495 (-2.7A)
AC1  A1496 (-4.7A)
GLC  A1493 (-3.5A)
GLC  A1495 (-4.0A)
 0.30A 6ag0A-1w9xA:
64.2		 6ag0A-1w9xA:
32.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 TRP A  58
TYR A  62
GLU A 240
TYR A 151
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.6A)
BGC  A 993 ( 3.3A)
BGC  A 993 (-4.2A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 1.30A 6ag0A-1oseA:
26.7		 6ag0A-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		9 / 12 TRP A  58
TYR A  62
HIS A 101
GLU A 240
ASP A 197
LYS A 200
HIS A 201
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.6A)
AC1  A 992 ( 3.7A)
BGC  A 993 ( 3.3A)
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 1.09A 6ag0A-1oseA:
26.7		 6ag0A-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		9 / 12 TRP A  58
TYR A  62
HIS A 101
LEU A 162
ASP A 197
LYS A 200
HIS A 201
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.6A)
AC1  A 992 ( 3.7A)
None
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.78A 6ag0A-1oseA:
26.7		 6ag0A-1oseA:
8.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		12 / 12 TRP A  15
TYR A  58
HIS A 107
GLU A 194
TYR A 198
LEU A 201
MET A 202
ASP A 236
LYS A 239
HIS A 240
HIS A 332
ASP A 333
 None
AC1  A1492 ( 3.9A)
AC1  A1492 (-4.3A)
GLC  A1491 (-2.9A)
GLC  A1491 ( 4.7A)
AC1  A1492 ( 4.9A)
GLC  A1493 (-3.5A)
AC1  A1492 (-3.0A)
GLC  A1491 (-2.5A)
AC1  A1492 ( 3.9A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.32A 6ag0A-1w9xA:
64.2		 6ag0A-1w9xA:
32.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 GLU A 240
ASP A 197
LYS A 200
HIS A 201
HIS A 299
ASP A 300
 BGC  A 993 ( 3.3A)
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 1.01A 6ag0C-1oseA:
26.7		 6ag0C-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 LEU A 162
ASP A 197
LYS A 200
HIS A 201
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.53A 6ag0C-1oseA:
26.7		 6ag0C-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 TRP A  58
GLU A 240
ASP A 197
LYS A 200
HIS A 201
HIS A 299
 None
BGC  A 993 ( 3.3A)
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 3.9A)
 1.10A 6ag0C-1oseA:
26.7		 6ag0C-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 TRP A  58
LEU A 162
ASP A 197
LYS A 200
HIS A 201
HIS A 299
 None
None
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 3.9A)
 0.73A 6ag0C-1oseA:
26.7		 6ag0C-1oseA:
8.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		10 / 12 TRP A  15
GLU A 194
TYR A 198
LEU A 201
MET A 202
ASP A 236
LYS A 239
HIS A 240
HIS A 332
ASP A 333
 None
GLC  A1491 (-2.9A)
GLC  A1491 ( 4.7A)
AC1  A1492 ( 4.9A)
GLC  A1493 (-3.5A)
AC1  A1492 (-3.0A)
GLC  A1491 (-2.5A)
AC1  A1492 ( 3.9A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.34A 6ag0C-1w9xA:
64.3		 6ag0C-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 12 TRP A  15
LEU A 201
MET A 202
ASP A 236
TYR A 295
HIS A 332
ASP A 333
 None
AC1  A1492 ( 4.9A)
GLC  A1493 (-3.5A)
AC1  A1492 (-3.0A)
BGC  A1490 ( 4.5A)
AC1  A1492 (-3.9A)
AC1  A1492 ( 3.0A)
 0.75A 6ag0C-1w9xA:
64.3		 6ag0C-1w9xA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AG0_C_ACRC609_0
(ALPHA-AMYLASE)		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		7 / 7 LYS A  72
GLY A 110
TRP A 140
ASP A 166
TRP A 167
MET A 202
TYR A 203
 AC1  A1496 (-2.9A)
AC1  A1496 (-3.4A)
AC1  A1496 (-3.7A)
GLC  A1495 (-2.7A)
AC1  A1496 (-4.7A)
GLC  A1493 (-3.5A)
GLC  A1495 (-4.0A)
 0.28A 6ag0C-1w9xA:
64.3		 6ag0C-1w9xA:
32.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1w9x ALPHA AMYLASE
(Bacillus
halmapalus) 		4 / 8 ARG A 234
VAL A 213
ARG A 148
GLN A  71
 AC1  A1492 (-3.3A)
None
None
None
 1.21A 6fbvD-1w9xA:
undetectable		 6fbvD-1w9xA:
16.60