SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ABL'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QWX_A_ML1A233_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1naa	CELLOBIOSE DEHYDROGENASE (Phanerochaete chrysosporium)	4 / 8	PHE A 282 PHE A 272 GLY A 299 ILE A 294	ABL A 901 (-4.1A) None None None	0.98A	2qwxA-1naaA: 2.5 2qwxB-1naaA: 3.0	2qwxA-1naaA: 17.77 2qwxB-1naaA: 17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QOI_A_ML1A303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1naa	CELLOBIOSE DEHYDROGENASE (Phanerochaete chrysosporium)	4 / 8	PHE A 282 PHE A 272 GLY A 299 ILE A 294	ABL A 901 (-4.1A) None None None	0.88A	4qoiA-1naaA: 3.3 4qoiB-1naaA: 3.3	4qoiA-1naaA: 17.77 4qoiB-1naaA: 17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KPC_A_SAMA401_1 (PAVINE N-METHYLTRANSFERASE)	1naa	CELLOBIOSE DEHYDROGENASE (Phanerochaete chrysosporium)	4 / 5	SER A 562 ASN A 517 GLN A 582 ASP A 516	ABL A 901 ( 4.2A) None None None	1.25A	5kpcA-1naaA: 2.0	5kpcA-1naaA: 19.35

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QWX_A_ML1A233_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","1naa","CELLOBIOSE DEHYDROGENASE","Phanerochaete chrysosporium",4,"PHE A 282;PHE A 272;GLY A 299;ILE A 294","ABL A 901 (-4.1A);None;None;None","0.98A","2qwxA-1naaA:2.5;2qwxB-1naaA:3.0",null],["4QOI_A_ML1A303_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","1naa","CELLOBIOSE DEHYDROGENASE","Phanerochaete chrysosporium",4,"PHE A 282;PHE A 272;GLY A 299;ILE A 294","ABL A 901 (-4.1A);None;None;None","0.88A","4qoiA-1naaA:3.3;4qoiB-1naaA:3.3","2qwxA-1naaA:17.77;2qwxB-1naaA:17.77"],["5KPC_A_SAMA401_1","PAVINE N-METHYLTRANSFERASE","1naa","CELLOBIOSE DEHYDROGENASE","Phanerochaete chrysosporium",4,"SER A 562;ASN A 517;GLN A 582;ASP A 516","ABL A 901 ( 4.2A);None;None;None","1.25A","5kpcA-1naaA:2.0","4qoiA-1naaA:17.77;4qoiB-1naaA:17.77"]]