SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ABF'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1o8b RIBOSE 5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		3 / 3 SER A  53
GLY A  27
GLY A  29
 None
None
ABF  A1269 ( 3.7A)
 0.54A 3bogA-1o8bA:
undetectable
3bogC-1o8bA:
undetectable		 3bogA-1o8bA:
undetectable
3bogC-1o8bA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1o8b RIBOSE 5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		3 / 3 SER A  30
ASP A  84
ASP A 170
 ABF  A1269 (-2.5A)
ABF  A1269 (-2.6A)
None
 0.91A 3uj7A-1o8bA:
undetectable		 3uj7A-1o8bA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 1o8b RIBOSE 5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 ASP A 170
ILE A 168
LEU A 100
ASP A  84
PHE A 129
 None
None
None
ABF  A1269 (-2.6A)
None
 1.39A 4b9zA-1o8bA:
undetectable		 4b9zA-1o8bA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1o8b RIBOSE 5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 GLY A 196
GLY A  95
GLY A  96
ALA A 199
LEU A 126
 None
ABF  A1269 (-3.9A)
ABF  A1269 (-3.7A)
None
None
 0.80A 5c0oF-1o8bA:
undetectable		 5c0oF-1o8bA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 1o8b RIBOSE 5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		4 / 8 GLY A 196
ARG A 157
ASP A 170
ASP A  84
 None
None
None
ABF  A1269 (-2.6A)
 0.96A 5vlmB-1o8bA:
undetectable		 5vlmB-1o8bA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 1o8b RIBOSE 5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		4 / 8 ILE A 168
ARG A 157
VAL A 171
ASP A  84
 None
None
None
ABF  A1269 (-2.6A)
 1.12A 5vlmF-1o8bA:
0.0		 5vlmF-1o8bA:
21.08