SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ABE'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1mfa IGG1-LAMBDA SE155-4
FAB (HEAVY CHAIN)
IGG1-LAMBDA SE155-4
FAB (LIGHT CHAIN)
(Mus
musculus) 		4 / 6 PHE H 309
TRP L  93
GLY H 350
GLY H 349
 ABE  H 503 ( 4.3A)
ABE  H 503 (-3.6A)
None
None
 0.90A 2qr2A-1mfaH:
0.0
2qr2B-1mfaH:
undetectable		 2qr2A-1mfaH:
20.79
2qr2B-1mfaH:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1mfa IGG1-LAMBDA SE155-4
FAB (HEAVY CHAIN)
IGG1-LAMBDA SE155-4
FAB (LIGHT CHAIN)
(Mus
musculus) 		4 / 5 TRP L  93
GLY H 350
GLY H 349
PHE H 309
 ABE  H 503 (-3.6A)
None
None
ABE  H 503 ( 4.3A)
 0.89A 2qr2A-1mfaL:
undetectable
2qr2B-1mfaL:
undetectable		 2qr2A-1mfaL:
22.32
2qr2B-1mfaL:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1mfa IGG1-LAMBDA SE155-4
FAB (HEAVY CHAIN)
IGG1-LAMBDA SE155-4
FAB (LIGHT CHAIN)
(Mus
musculus) 		4 / 8 PHE H 309
TRP L  93
GLY H 350
GLY H 349
 ABE  H 503 ( 4.3A)
ABE  H 503 (-3.6A)
None
None
 0.84A 2qx4A-1mfaH:
undetectable
2qx4B-1mfaH:
undetectable		 2qx4A-1mfaH:
20.79
2qx4B-1mfaH:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 1mfa IGG1-LAMBDA SE155-4
FAB (LIGHT CHAIN)
(Mus
musculus) 		4 / 5 TRP L  98
GLY L  51
ALA L  35
PHE L 100
 ABE  H 503 (-3.9A)
None
None
None
 1.36A 3wqwA-1mfaL:
0.0		 3wqwA-1mfaL:
16.24