SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'AAL'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 8 TYR A 186
PHE A 164
GLN A 180
ASP A 245
 None
None
AAL  A 502 (-3.2A)
AAL  A 502 (-2.7A)
 0.92A 3mjrD-5ta9A:
undetectable		 3mjrD-5ta9A:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)		 5ta9 GLYCOSIDE HYDROLASE
(Bacteroides
uniformis) 		4 / 7 HIS A 302
ASP A  90
HIS A 244
HIS A 371
 GAL  A 501 (-3.9A)
AAL  A 502 ( 3.7A)
AAL  A 502 (-3.3A)
None
 1.24A 3zodA-5ta9A:
undetectable		 3zodA-5ta9A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2cdp BETA-AGARASE 1
(Saccharophagus
degradans) 		4 / 8 TYR A  30
PHE A 100
GLY A  68
ASN A 130
 AAL  A1006 ( 4.8A)
None
None
AAL  A1006 (-3.4A)
 0.97A 4qoiA-2cdpA:
undetectable
4qoiB-2cdpA:
undetectable		 4qoiA-2cdpA:
20.87
4qoiB-2cdpA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 2cdp BETA-AGARASE 1
(Saccharophagus
degradans) 		5 / 12 GLY A  72
GLY A 121
ALA A 122
SER A  28
TYR A  40
 None
None
None
None
AAL  A1006 ( 3.8A)
 1.00A 4rtmA-2cdpA:
undetectable		 4rtmA-2cdpA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4bq4 B-AGARASE
(Saccharophagus
degradans) 		3 / 3 ASP A 755
ASN A 533
GLN A 534
 None
GAL  A1795 ( 3.3A)
AAL  A1796 ( 3.1A)
 0.78A 5k7uA-4bq4A:
undetectable		 5k7uA-4bq4A:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 1urx BETA-AGARASE A
(Zobellia
galactanivorans) 		3 / 3 TYR A 106
PRO A  99
LEU A 268
 AAL  A1293 ( 3.9A)
None
None
 0.91A 6beoA-1urxA:
undetectable		 6beoA-1urxA:
3.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 4atf BETA-AGARASE B
(Zobellia
galactanivorans) 		3 / 3 TYR A 225
ASP A 224
GLN A 226
 None
None
AAL  A1358 (-3.4A)
 0.94A 6g1pA-4atfA:
undetectable		 6g1pA-4atfA:
21.29