SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'A2Q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2R6V_A_NCAA174_0 (UNCHARACTERIZED PROTEIN PH0856)	3zog	FMN-BINDING PROTEIN (Pyrococcus horikoshii)	6 / 6	TYR A 8 HIS A -7 ASP A 29 TRP A 30 ARG A 49 HIS A 124	None A2Q A 200 (-4.2A) FMN A 173 (-3.3A) A2Q A 200 ( 3.3A) FMN A 173 ( 3.5A) A2Q A 200 ( 3.8A)	0.22A	2r6vA-3zogA: 34.0	2r6vA-3zogA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ZOD_A_HQEA1173_1 (FMN-BINDING PROTEIN)	3zog	FMN-BINDING PROTEIN (Pyrococcus horikoshii)	7 / 7	TYR A 8 HIS A -7 ASP A 29 TRP A 30 ARG A 49 HIS A 124 HIS A 155	None A2Q A 200 (-4.2A) FMN A 173 (-3.3A) A2Q A 200 ( 3.3A) FMN A 173 ( 3.5A) A2Q A 200 ( 3.8A) FMN A 173 (-3.6A)	0.11A	3zodA-3zogA: 34.3	3zodA-3zogA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOF_A_HQEA200_1 (FLAVOREDOXIN)	3zog	FMN-BINDING PROTEIN (Pyrococcus horikoshii)	4 / 5	TYR A 8 TRP A 30 ARG A 49 HIS A 124	None A2Q A 200 ( 3.3A) FMN A 173 ( 3.5A) A2Q A 200 ( 3.8A)	0.47A	3zofA-3zogA: 24.1	3zofA-3zogA: 28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOF_B_HQEB200_1 (FLAVOREDOXIN)	3zog	FMN-BINDING PROTEIN (Pyrococcus horikoshii)	4 / 5	TYR A 8 TRP A 30 ARG A 49 HIS A 124	None A2Q A 200 ( 3.3A) FMN A 173 ( 3.5A) A2Q A 200 ( 3.8A)	0.45A	3zofB-3zogA: 23.9	3zofB-3zogA: 28.14

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2R6V_A_NCAA174_0","UNCHARACTERIZED PROTEIN PH0856","3zog","FMN-BINDING PROTEIN","Pyrococcus horikoshii",6,"TYR A   8;HIS A  -7;ASP A  29;TRP A  30;ARG A  49;HIS A 124","None;A2Q A 200 (-4.2A);FMN A 173 (-3.3A);A2Q A 200 ( 3.3A);FMN A 173 ( 3.5A);A2Q A 200 ( 3.8A)","0.22A","2r6vA-3zogA:34.0",null],["3ZOD_A_HQEA1173_1","FMN-BINDING PROTEIN","3zog","FMN-BINDING PROTEIN","Pyrococcus horikoshii",7,"TYR A   8;HIS A  -7;ASP A  29;TRP A  30;ARG A  49;HIS A 124;HIS A 155","None;A2Q A 200 (-4.2A);FMN A 173 (-3.3A);A2Q A 200 ( 3.3A);FMN A 173 ( 3.5A);A2Q A 200 ( 3.8A);FMN A 173 (-3.6A)","0.11A","3zodA-3zogA:34.3","2r6vA-3zogA:100.00"],["3ZOF_A_HQEA200_1","FLAVOREDOXIN","3zog","FMN-BINDING PROTEIN","Pyrococcus horikoshii",4,"TYR A   8;TRP A  30;ARG A  49;HIS A 124","None;A2Q A 200 ( 3.3A);FMN A 173 ( 3.5A);A2Q A 200 ( 3.8A)","0.47A","3zofA-3zogA:24.1","3zodA-3zogA:100.00"],["3ZOF_B_HQEB200_1","FLAVOREDOXIN","3zog","FMN-BINDING PROTEIN","Pyrococcus horikoshii",4,"TYR A   8;TRP A  30;ARG A  49;HIS A 124","None;A2Q A 200 ( 3.3A);FMN A 173 ( 3.5A);A2Q A 200 ( 3.8A)","0.45A","3zofB-3zogA:23.9","3zofA-3zogA:28.14"]]