SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'A2G'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1E06_B_IPBB600_0 (ODORANT-BINDINGPROTEIN) |
2ixb | ALPHA-N-ACETYLGALACTOSAMINIDASE (Elizabethkingiameningoseptica) | 4 / 4 | ILE A 295MET A 236VAL A 151GLY A 175 | NoneNoneA2G A1446 (-4.9A)None | 1.35A | 1e06B-2ixbA:undetectable | 1e06B-2ixbA:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1HRK_B_CHDB2503_0 (FERROCHELATASE) |
5veb | CADHERIN-6 (Homosapiens) | 4 / 4 | LEU X 566PRO X 567LEU X 527ARG X 552 | NoneA2G X2002 ( 4.9A)NoneNone | 1.41A | 1hrkB-5vebX:undetectable | 1hrkB-5vebX:15.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ISM_B_NCAB305_0 (BONE MARROW STROMALCELL ANTIGEN 1) |
1lu2 | LECTIN (Vignaunguiculata) | 4 / 7 | HIS A 138LEU A 127SER A 128ASP A 133 | MN A 302 (-3.7A)A2G A 254 ( 4.6A)None CA A 301 ( 3.0A) | 1.29A | 1ismB-1lu2A:undetectable | 1ismB-1lu2A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1TDN_A_LEUA487_0 (L-AMINO ACID OXIDASE) |
2w7y | PROBABLE SUGAR ABCTRANSPORTER,SUGAR-BINDINGPROTEIN (Streptococcuspneumoniae) | 4 / 7 | ARG A 207ASN A 106PHE A 155TRP A 280 | A2G A1428 (-3.3A)A2G A1428 (-3.8A)GAL A1429 ( 4.5A)GAL A1429 ( 3.6A) | 1.09A | 1tdnA-2w7yA:undetectable | 1tdnA-2w7yA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FCN_B_DVAB35_0 (UBIQUITIN) |
1lu2 | LECTIN (Vignaunguiculata) | 4 / 6 | LEU A 214GLU A 220ILE A 219PRO A 42 | A2G A 254 (-4.1A)NoneNoneNone | 0.90A | 2fcnA-1lu2A:undetectable2fcnB-1lu2A:0.0 | 2fcnA-1lu2A:14.682fcnB-1lu2A:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2HRC_B_CHDB1604_0 (FERROCHELATASE) |
5veb | CADHERIN-6 (Homosapiens) | 4 / 4 | LEU X 566PRO X 567LEU X 527ARG X 552 | NoneA2G X2002 ( 4.9A)NoneNone | 1.40A | 2hrcB-5vebX:undetectable | 2hrcB-5vebX:15.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2QEI_A_CXXA802_1 (TRANSPORTER) |
2w7y | PROBABLE SUGAR ABCTRANSPORTER,SUGAR-BINDINGPROTEIN (Streptococcuspneumoniae) | 4 / 6 | ARG A 207PHE A 209ILE A 398PHE A 237 | A2G A1428 (-3.3A)NoneNoneNone | 1.21A | 2qeiA-2w7yA:undetectable | 2qeiA-2w7yA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3BJW_E_SVRE503_1 (PHOSPHOLIPASE A2) |
2a2d | N-ACETYLGALACTOSAMINE KINASE (Homosapiens) | 5 / 11 | VAL A 134GLY A 136ILE A 138SER A 146SER A 148 | NoneANP A 461 (-3.6A)NoneANP A 461 (-2.7A)A2G A 459 (-3.3A) | 1.30A | 3bjwE-2a2dA:undetectable | 3bjwE-2a2dA:15.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3DH0_A_SAMA220_0 (SAM DEPENDENTMETHYLTRANSFERASE) |
2e7t | BASIC AGGLUTININ (Psophocarpustetragonolobus) | 5 / 12 | GLY A 88ALA A 86PHE A 126THR A 125LEU A 154 | NoneA2G A 400 ( 4.3A)A2G A 400 ( 3.8A)NoneNone | 0.67A | 3dh0A-2e7tA:undetectable | 3dh0A-2e7tA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FXR_A_ASCA3001_0 (LYSR TYPE REGULATOROF TSAMBCD) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 4 / 8 | HIS A 133ARG A 135ALA A 10PRO A 113 | A2G A 203 (-4.0A)NoneNoneNone | 1.00A | 3fxrA-5xg5A:undetectable | 3fxrA-5xg5A:15.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GAL_A_1GNA998_1 (GALECTIN-7) |
3ayd | GALECTIN-3 (Homosapiens) | 6 / 6 | HIS A 158ASN A 160ARG A 162ASN A 174TRP A 181GLU A 184 | GAL A 253 (-3.7A)GAL A 253 (-4.1A)A2G A 252 ( 3.1A)GAL A 253 (-3.9A)GAL A 253 (-3.5A)A2G A 252 (-3.0A) | 0.22A | 3galA-3aydA:22.4 | 3galA-3aydA:35.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GAL_B_1GNB999_1 (GALECTIN-7) |
3ayd | GALECTIN-3 (Homosapiens) | 6 / 6 | HIS A 158ASN A 160ARG A 162ASN A 174TRP A 181GLU A 184 | GAL A 253 (-3.7A)GAL A 253 (-4.1A)A2G A 252 ( 3.1A)GAL A 253 (-3.9A)GAL A 253 (-3.5A)A2G A 252 (-3.0A) | 0.34A | 3galB-3aydA:22.7 | 3galB-3aydA:35.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3IB0_A_DIFA701_1 (LACTOTRANSFERRIN) |
2e7t | BASIC AGGLUTININ (Psophocarpustetragonolobus) | 4 / 4 | PRO A 112TYR A 106GLY A 101THR A 100 | NoneA2G A 400 ( 4.7A)NoneNone | 0.92A | 3ib0A-2e7tA:undetectable | 3ib0A-2e7tA:21.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3JZJ_A_ACRA405_1 (ACARBOSE/MALTOSEBINDING PROTEIN GACH) |
2w7y | PROBABLE SUGAR ABCTRANSPORTER,SUGAR-BINDINGPROTEIN (Streptococcuspneumoniae) | 5 / 12 | GLY A 105GLU A 203ALA A 260GLY A 202ASN A 277 | A2G A1428 (-3.8A)A2G A1428 (-2.7A)A2G A1428 (-3.4A)NoneA2G A1428 ( 2.9A) | 1.30A | 3jzjA-2w7yA:29.0 | 3jzjA-2w7yA:30.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3K4V_B_ROCB201_4 (HIV-1 PROTEASE) |
2e7t | BASIC AGGLUTININ (Psophocarpustetragonolobus) | 4 / 4 | ARG A 77ASP A 124GLY A 104THR A 34 | None CA A 303 ( 2.3A)A2G A 400 (-3.5A)None | 1.05A | 3k4vB-2e7tA:undetectable | 3k4vB-2e7tA:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MIH_A_CUA358_0 (PEPTIDYL-GLYCINEALPHA-AMIDATINGMONOOXYGENASE) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 3 / 3 | HIS A 37HIS A 16MET A 40 | A2G A 201 (-4.0A)A2G A 201 (-3.7A)None | 0.89A | 3mihA-5xg5A:undetectable | 3mihA-5xg5A:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MIH_A_CUA358_0 (PEPTIDYL-GLYCINEALPHA-AMIDATINGMONOOXYGENASE) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 3 / 3 | HIS A 85HIS A 64MET A 88 | A2G A 202 (-4.0A)A2G A 202 (-3.7A)None | 0.89A | 3mihA-5xg5A:undetectable | 3mihA-5xg5A:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MIH_A_CUA358_0 (PEPTIDYL-GLYCINEALPHA-AMIDATINGMONOOXYGENASE) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 3 / 3 | HIS A 133HIS A 112MET A 136 | A2G A 203 (-4.0A)A2G A 203 (-3.7A)None | 0.89A | 3mihA-5xg5A:undetectable | 3mihA-5xg5A:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3TJ7_A_ACTA609_0 (GBAA_1210 PROTEIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 3 / 3 | LYS A 66VAL A 79HIS A 81 | A2G A 202 (-4.7A)NoneA2G A 202 (-3.9A) | 1.21A | 3tj7A-5xg5A:undetectable | 3tj7A-5xg5A:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4DU2_A_LDPA501_1 (CYTOCHROME P450 BM3VARIANT B7) |
5jpn | COMPLEMENT C4-A (Homosapiens) | 4 / 7 | ALA B1268ALA B1221ALA B1190LEU B1217 | NoneA2G B1508 (-4.5A)NoneNone | 0.90A | 4du2A-5jpnB:undetectable | 4du2A-5jpnB:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4DU2_B_LDPB501_1 (CYTOCHROME P450 BM3VARIANT B7) |
5jpn | COMPLEMENT C4-A (Homosapiens) | 4 / 7 | ALA B1268ALA B1221ALA B1190LEU B1217 | NoneA2G B1508 (-4.5A)NoneNone | 0.85A | 4du2B-5jpnB:undetectable | 4du2B-5jpnB:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4E7B_C_ACTC513_0 (UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE) |
1jlx | AGGLUTININ (Amaranthuscaudatus) | 3 / 3 | TYR A 76HIS A 119ARG A 70 | A2G A 305 ( 3.4A)NoneNone | 0.74A | 4e7bC-1jlxA:0.0 | 4e7bC-1jlxA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4HVR_A_SALA203_1 (3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 4 / 7 | HIS A 33ASP A 35HIS A 16PRO A 17 | A2G A 201 (-3.7A)A2G A 201 (-3.5A)A2G A 201 (-3.7A)None | 1.06A | 4hvrA-5xg5A:undetectable | 4hvrA-5xg5A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4HVR_A_SALA203_1 (3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 4 / 7 | HIS A 81ASP A 83HIS A 64PRO A 65 | A2G A 202 (-3.9A)A2G A 202 (-3.6A)A2G A 202 (-3.7A)None | 1.10A | 4hvrA-5xg5A:undetectable | 4hvrA-5xg5A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4HVR_A_SALA203_1 (3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 4 / 7 | HIS A 129ASP A 131HIS A 112PRO A 113 | A2G A 203 (-3.8A)A2G A 203 (-3.6A)A2G A 203 (-3.7A)None | 1.05A | 4hvrA-5xg5A:undetectable | 4hvrA-5xg5A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4K36_B_SAMB504_0 (ANAEROBICSULFATASE-MATURATINGENZYME) |
2a2d | N-ACETYLGALACTOSAMINE KINASE (Homosapiens) | 5 / 12 | GLU A 49ASN A 45LEU A 144ILE A 138LEU A 150 | A2G A 459 (-3.5A)NoneNoneNoneANP A 461 (-4.6A) | 1.22A | 4k36B-2a2dA:undetectable | 4k36B-2a2dA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4K37_B_SAMB504_0 (ANAEROBICSULFATASE-MATURATINGENZYME) |
2a2d | N-ACETYLGALACTOSAMINE KINASE (Homosapiens) | 5 / 11 | GLU A 49ASN A 45LEU A 144ILE A 138LEU A 150 | A2G A 459 (-3.5A)NoneNoneNoneANP A 461 (-4.6A) | 1.17A | 4k37B-2a2dA:undetectable | 4k37B-2a2dA:21.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4Q56_A_ACTA201_0 (HELIX ASPERSAAGGLUTININ (HAA)) |
4q56 | HELIX ASPERSAAGGLUTININ (HAA) (Helixaspersa) | 4 / 4 | ASN A 62ARG A 64HIS A 85ASN A 86 | A2G A 202 ( 3.8A)A2G A 202 ( 3.8A) ZN A 210 (-3.2A)ACT A 201 (-3.5A) | 0.00A | 4q56A-4q56A:22.0 | 4q56A-4q56A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QB9_E_PARE500_1 (ENHANCEDINTRACELLULARSURVIVAL PROTEIN) |
1fnz | BARK AGGLUTININ I,POLYPEPTIDE A (Robiniapseudoacacia) | 5 / 12 | TYR A 220GLU A 125ASP A 87ASP A 127GLY A 138 | A2G A 555 (-3.2A)NoneA2G A 555 (-2.9A) CA A 500 (-2.2A)None | 1.50A | 4qb9E-1fnzA:0.0 | 4qb9E-1fnzA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QB9_F_PARF500_1 (ENHANCEDINTRACELLULARSURVIVAL PROTEIN) |
1fnz | BARK AGGLUTININ I,POLYPEPTIDE A (Robiniapseudoacacia) | 5 / 11 | TYR A 220GLU A 125ASP A 87ASP A 127GLY A 138 | A2G A 555 (-3.2A)NoneA2G A 555 (-2.9A) CA A 500 (-2.2A)None | 1.48A | 4qb9F-1fnzA:0.0 | 4qb9F-1fnzA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ZZ8_A_GCSA208_1 (GLUCANASE/CHITOSANASE) |
2w7y | PROBABLE SUGAR ABCTRANSPORTER,SUGAR-BINDINGPROTEIN (Streptococcuspneumoniae) | 4 / 7 | GLU A 203ASP A 259ALA A 260TYR A 263 | A2G A1428 (-2.7A)NoneA2G A1428 (-3.4A)None | 1.20A | 4zz8A-2w7yA:undetectable | 4zz8A-2w7yA:16.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA201_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 9 | HIS A 16GLY A 19GLY A 20VAL A 31HIS A 33ASP A 35HIS A 37 | A2G A 201 (-3.7A)A2G A 201 (-3.3A)A2G A 201 (-3.1A)NoneA2G A 201 (-3.7A)A2G A 201 (-3.5A)A2G A 201 (-4.0A) | 0.16A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA201_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 5 / 9 | HIS A 16GLY A 20VAL A 31HIS A 33ASP A 35 | A2G A 201 (-3.7A)A2G A 201 (-3.1A)NoneA2G A 201 (-3.7A)A2G A 201 (-3.5A) | 0.79A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA201_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 9 | HIS A 64GLY A 67GLY A 68VAL A 79HIS A 81ASP A 83HIS A 85 | A2G A 202 (-3.7A)A2G A 202 (-3.3A)A2G A 202 (-3.3A)NoneA2G A 202 (-3.9A)A2G A 202 (-3.6A)A2G A 202 (-4.0A) | 0.13A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA201_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 5 / 9 | HIS A 64GLY A 68VAL A 79HIS A 81ASP A 83 | A2G A 202 (-3.7A)A2G A 202 (-3.3A)NoneA2G A 202 (-3.9A)A2G A 202 (-3.6A) | 0.86A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA201_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 9 | HIS A 112GLY A 115GLY A 116VAL A 127HIS A 129ASP A 131HIS A 133 | A2G A 203 (-3.7A)A2G A 203 (-3.2A)A2G A 203 (-3.2A)NoneA2G A 203 (-3.8A)A2G A 203 (-3.6A)A2G A 203 (-4.0A) | 0.14A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA202_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 8 | HIS A 16GLY A 19GLY A 20VAL A 31HIS A 33ASP A 35HIS A 37 | A2G A 201 (-3.7A)A2G A 201 (-3.3A)A2G A 201 (-3.1A)NoneA2G A 201 (-3.7A)A2G A 201 (-3.5A)A2G A 201 (-4.0A) | 0.16A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA202_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 5 / 8 | HIS A 16GLY A 20VAL A 31HIS A 33ASP A 35 | A2G A 201 (-3.7A)A2G A 201 (-3.1A)NoneA2G A 201 (-3.7A)A2G A 201 (-3.5A) | 0.85A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA202_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 8 | HIS A 64GLY A 67GLY A 68VAL A 79HIS A 81ASP A 83HIS A 85 | A2G A 202 (-3.7A)A2G A 202 (-3.3A)A2G A 202 (-3.3A)NoneA2G A 202 (-3.9A)A2G A 202 (-3.6A)A2G A 202 (-4.0A) | 0.16A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA202_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 5 / 8 | HIS A 64GLY A 67VAL A 79HIS A 81ASP A 83 | A2G A 202 (-3.7A)A2G A 202 (-3.3A)NoneA2G A 202 (-3.9A)A2G A 202 (-3.6A) | 0.84A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA202_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 8 | HIS A 112GLY A 115GLY A 116VAL A 127HIS A 129ASP A 131HIS A 133 | A2G A 203 (-3.7A)A2G A 203 (-3.2A)A2G A 203 (-3.2A)NoneA2G A 203 (-3.8A)A2G A 203 (-3.6A)A2G A 203 (-4.0A) | 0.14A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA203_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 9 | HIS A 16GLY A 19GLY A 20VAL A 31HIS A 33ASP A 35HIS A 37 | A2G A 201 (-3.7A)A2G A 201 (-3.3A)A2G A 201 (-3.1A)NoneA2G A 201 (-3.7A)A2G A 201 (-3.5A)A2G A 201 (-4.0A) | 0.15A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA203_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 9 | HIS A 64GLY A 67GLY A 68VAL A 79HIS A 81ASP A 83HIS A 85 | A2G A 202 (-3.7A)A2G A 202 (-3.3A)A2G A 202 (-3.3A)NoneA2G A 202 (-3.9A)A2G A 202 (-3.6A)A2G A 202 (-4.0A) | 0.12A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA203_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 9 | HIS A 112GLY A 115GLY A 116VAL A 127HIS A 129ASP A 131HIS A 133 | A2G A 203 (-3.7A)A2G A 203 (-3.2A)A2G A 203 (-3.2A)NoneA2G A 203 (-3.8A)A2G A 203 (-3.6A)A2G A 203 (-4.0A) | 0.12A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_A_X6XA203_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 5 / 9 | HIS A 112GLY A 115VAL A 127HIS A 129ASP A 131 | A2G A 203 (-3.7A)A2G A 203 (-3.2A)NoneA2G A 203 (-3.8A)A2G A 203 (-3.6A) | 0.86A | 5f8yA-5xg5A:27.0 | 5f8yA-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB201_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 8 | HIS A 16GLY A 19GLY A 20VAL A 31HIS A 33ASP A 35HIS A 37 | A2G A 201 (-3.7A)A2G A 201 (-3.3A)A2G A 201 (-3.1A)NoneA2G A 201 (-3.7A)A2G A 201 (-3.5A)A2G A 201 (-4.0A) | 0.21A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB201_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 5 / 8 | HIS A 16GLY A 19VAL A 31HIS A 33ASP A 35 | A2G A 201 (-3.7A)A2G A 201 (-3.3A)NoneA2G A 201 (-3.7A)A2G A 201 (-3.5A) | 0.83A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB201_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 8 | HIS A 64GLY A 67GLY A 68VAL A 79HIS A 81ASP A 83HIS A 85 | A2G A 202 (-3.7A)A2G A 202 (-3.3A)A2G A 202 (-3.3A)NoneA2G A 202 (-3.9A)A2G A 202 (-3.6A)A2G A 202 (-4.0A) | 0.21A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB201_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 5 / 8 | HIS A 64GLY A 67VAL A 79HIS A 81ASP A 83 | A2G A 202 (-3.7A)A2G A 202 (-3.3A)NoneA2G A 202 (-3.9A)A2G A 202 (-3.6A) | 0.75A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB201_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 8 | HIS A 112GLY A 115GLY A 116VAL A 127HIS A 129ASP A 131HIS A 133 | A2G A 203 (-3.7A)A2G A 203 (-3.2A)A2G A 203 (-3.2A)NoneA2G A 203 (-3.8A)A2G A 203 (-3.6A)A2G A 203 (-4.0A) | 0.21A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB201_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 5 / 8 | HIS A 112GLY A 115VAL A 127HIS A 129ASP A 131 | A2G A 203 (-3.7A)A2G A 203 (-3.2A)NoneA2G A 203 (-3.8A)A2G A 203 (-3.6A) | 0.81A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB202_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 9 | HIS A 16GLY A 19GLY A 20VAL A 31HIS A 33ASP A 35HIS A 37 | A2G A 201 (-3.7A)A2G A 201 (-3.3A)A2G A 201 (-3.1A)NoneA2G A 201 (-3.7A)A2G A 201 (-3.5A)A2G A 201 (-4.0A) | 0.17A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB202_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 5 / 9 | HIS A 16GLY A 19VAL A 31HIS A 33ASP A 35 | A2G A 201 (-3.7A)A2G A 201 (-3.3A)NoneA2G A 201 (-3.7A)A2G A 201 (-3.5A) | 0.83A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB202_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 9 | HIS A 64GLY A 67GLY A 68VAL A 79HIS A 81ASP A 83HIS A 85 | A2G A 202 (-3.7A)A2G A 202 (-3.3A)A2G A 202 (-3.3A)NoneA2G A 202 (-3.9A)A2G A 202 (-3.6A)A2G A 202 (-4.0A) | 0.16A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB202_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 9 | HIS A 112GLY A 115GLY A 116VAL A 127HIS A 129ASP A 131HIS A 133 | A2G A 203 (-3.7A)A2G A 203 (-3.2A)A2G A 203 (-3.2A)NoneA2G A 203 (-3.8A)A2G A 203 (-3.6A)A2G A 203 (-4.0A) | 0.15A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB202_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 5 / 9 | HIS A 112GLY A 115VAL A 127HIS A 129ASP A 131 | A2G A 203 (-3.7A)A2G A 203 (-3.2A)NoneA2G A 203 (-3.8A)A2G A 203 (-3.6A) | 0.82A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB203_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 9 | HIS A 16GLY A 19GLY A 20VAL A 31HIS A 33ASP A 35HIS A 37 | A2G A 201 (-3.7A)A2G A 201 (-3.3A)A2G A 201 (-3.1A)NoneA2G A 201 (-3.7A)A2G A 201 (-3.5A)A2G A 201 (-4.0A) | 0.22A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB203_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 5 / 9 | HIS A 16GLY A 20VAL A 31HIS A 33ASP A 35 | A2G A 201 (-3.7A)A2G A 201 (-3.1A)NoneA2G A 201 (-3.7A)A2G A 201 (-3.5A) | 0.77A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB203_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 9 | HIS A 64GLY A 67GLY A 68VAL A 79HIS A 81ASP A 83HIS A 85 | A2G A 202 (-3.7A)A2G A 202 (-3.3A)A2G A 202 (-3.3A)NoneA2G A 202 (-3.9A)A2G A 202 (-3.6A)A2G A 202 (-4.0A) | 0.14A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB203_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 7 / 9 | HIS A 112GLY A 115GLY A 116VAL A 127HIS A 129ASP A 131HIS A 133 | A2G A 203 (-3.7A)A2G A 203 (-3.2A)A2G A 203 (-3.2A)NoneA2G A 203 (-3.8A)A2G A 203 (-3.6A)A2G A 203 (-4.0A) | 0.19A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5F8Y_B_X6XB203_1 (GALNAC/GAL-SPECIFICLECTIN) |
5xg5 | MITSUBA-1 (syntheticconstruct) | 5 / 9 | HIS A 112GLY A 116VAL A 127HIS A 129ASP A 131 | A2G A 203 (-3.7A)A2G A 203 (-3.2A)NoneA2G A 203 (-3.8A)A2G A 203 (-3.6A) | 0.79A | 5f8yB-5xg5A:27.0 | 5f8yB-5xg5A:59.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5FHZ_D_READ602_1 (ALDEHYDEDEHYDROGENASE FAMILY1 MEMBER A3) |
2a2d | N-ACETYLGALACTOSAMINE KINASE (Homosapiens) | 5 / 12 | GLU A 185GLY A 186GLU A 338CYH A 377CYH A 371 | NoneA2G A 459 (-3.3A)NoneNoneNone | 1.50A | 5fhzD-2a2dA:undetectable | 5fhzD-2a2dA:24.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5L1F_C_6ZPC902_1 (GLUTAMATE RECEPTOR 2) |
2e7t | BASIC AGGLUTININ (Psophocarpustetragonolobus) | 4 / 7 | SER A 214ASP A 212TYR A 106PHE A 126 | GAL A 401 ( 3.1A)A2G A 400 (-4.9A)A2G A 400 ( 4.7A)A2G A 400 ( 3.8A) | 1.24A | 5l1fC-2e7tA:undetectable | 5l1fC-2e7tA:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5O96_C_SAMC501_0 (RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE E) |
2e7t | BASIC AGGLUTININ (Psophocarpustetragonolobus) | 5 / 7 | GLY A 104GLY A 211LEU A 33THR A 46ALA A 208 | A2G A 400 (-3.5A)A2G A 400 (-3.4A)NoneNoneNone | 1.38A | 5o96C-2e7tA:undetectable | 5o96C-2e7tA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5UUN_A_ACTA304_0 (GLUTATHIONES-TRANSFERASE-LIKEPROTEIN) |
2w7y | PROBABLE SUGAR ABCTRANSPORTER,SUGAR-BINDINGPROTEIN (Streptococcuspneumoniae) | 4 / 4 | ARG A 207THR A 385GLY A 105PHE A 155 | A2G A1428 (-3.3A)NoneA2G A1428 (-3.8A)GAL A1429 ( 4.5A) | 1.05A | 5uunA-2w7yA:0.2 | 5uunA-2w7yA:22.37 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6B8K_A_W9TA300_0 (GALECTIN-3) |
3ayd | GALECTIN-3 (Homosapiens) | 7 / 7 | HIS A 158ASN A 160ARG A 162ASN A 174TRP A 181GLU A 184ARG A 186 | GAL A 253 (-3.7A)GAL A 253 (-4.1A)A2G A 252 ( 3.1A)GAL A 253 (-3.9A)GAL A 253 (-3.5A)A2G A 252 (-3.0A)GAL A 256 ( 3.8A) | 0.21A | 6b8kA-3aydA:27.3 | 6b8kA-3aydA:93.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6B94_A_W9TA201_0 (GALECTIN-1) |
3ayd | GALECTIN-3 (Homosapiens) | 7 / 8 | HIS A 158ASN A 160ARG A 162ASN A 174TRP A 181GLU A 184ARG A 186 | GAL A 253 (-3.7A)GAL A 253 (-4.1A)A2G A 252 ( 3.1A)GAL A 253 (-3.9A)GAL A 253 (-3.5A)A2G A 252 (-3.0A)GAL A 256 ( 3.8A) | 0.43A | 6b94A-3aydA:19.4 | 6b94A-3aydA:34.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6B94_B_W9TB201_0 (GALECTIN-1) |
3ayd | GALECTIN-3 (Homosapiens) | 7 / 10 | HIS A 158ASN A 160ARG A 162ASN A 174TRP A 181GLU A 184ARG A 186 | GAL A 253 (-3.7A)GAL A 253 (-4.1A)A2G A 252 ( 3.1A)GAL A 253 (-3.9A)GAL A 253 (-3.5A)A2G A 252 (-3.0A)GAL A 256 ( 3.8A) | 0.41A | 6b94A-3aydA:19.46b94B-3aydA:19.1 | 6b94A-3aydA:34.786b94B-3aydA:34.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6FGD_A_ACTA826_0 (GEPHYRIN) |
2w7y | PROBABLE SUGAR ABCTRANSPORTER,SUGAR-BINDINGPROTEIN (Streptococcuspneumoniae) | 3 / 3 | HIS A 395ARG A 207ILE A 206 | NoneA2G A1428 (-3.3A)None | 0.78A | 6fgdA-2w7yA:undetectable | 6fgdA-2w7yA:22.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6FK2_A_SORA302_0 (GALECTIN-3) |
3ayd | GALECTIN-3 (Homosapiens) | 4 / 4 | ARG A 162GLU A 165GLU A 184ARG A 186 | A2G A 252 ( 3.1A)NoneA2G A 252 (-3.0A)GAL A 256 ( 3.8A) | 0.31A | 6fk2A-3aydA:27.4 | 6fk2A-3aydA:97.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6FK2_A_SORA302_0 (GALECTIN-3) |
3ayd | GALECTIN-3 (Homosapiens) | 4 / 4 | ARG A 186GLU A 184GLU A 165ARG A 162 | GAL A 256 ( 3.8A)A2G A 252 (-3.0A)NoneA2G A 252 ( 3.1A) | 0.96A | 6fk2A-3aydA:27.4 | 6fk2A-3aydA:97.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6GNE_B_ACRB602_1 (-) |
6ejj | WLAC PROTEIN (Campylobacterjejuni) | 5 / 12 | GLU A 18GLY A 15GLY A 16VAL A 20ASN A 166 | A2G A 406 ( 3.1A)A2G A 406 (-3.4A)UDP A 401 (-3.0A)NoneNone | 0.69A | 6gneB-6ejjA:26.6 | 6gneB-6ejjA:9.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6GNE_B_ACRB602_1 (-) |
6ejj | WLAC PROTEIN (Campylobacterjejuni) | 5 / 12 | GLU A 18GLY A 16VAL A 20ASN A 166ARG A 191 | A2G A 406 ( 3.1A)UDP A 401 (-3.0A)NoneNoneUDP A 401 (-3.5A) | 0.93A | 6gneB-6ejjA:26.6 | 6gneB-6ejjA:9.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6GNG_A_QPSA601_2 (-) |
6ejj | WLAC PROTEIN (Campylobacterjejuni) | 5 / 12 | GLU A 18GLY A 16HIS A 118ARG A 191GLU A 267 | A2G A 406 ( 3.1A)UDP A 401 (-3.0A) CL A 404 ( 4.5A)UDP A 401 (-3.5A) NA A 403 (-3.6A) | 1.02A | 6gngA-6ejjA:13.5 | 6gngA-6ejjA:9.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6MN1_B_LLLB302_0 (AMINOGLYCOSIDEN(3)-ACETYLTRANSFERASE) |
1lu2 | LECTIN (Vignaunguiculata) | 5 / 10 | ASP A 85GLY A 102ASP A 223THR A 221SER A 209 | A2G A 254 (-2.7A)A2G A 254 (-3.7A)NoneNoneNone | 1.46A | 6mn1B-1lu2A:0.0 | 6mn1B-1lu2A:16.16 |