SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'A1V'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1372_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5w99 PBTD
(Planobispora
rosea) 		4 / 5 SER A 178
TYR A 285
PHE A 179
VAL A 317
 A1V  A 401 (-2.8A)
None
None
None
 1.47A 2x7hB-5w99A:
undetectable		 2x7hB-5w99A:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5w99 PBTD
(Planobispora
rosea) 		4 / 7 LEU A 266
ARG A 180
SER A 279
GLY A 175
 A1V  A 401 (-4.3A)
None
None
A1V  A 401 ( 4.8A)
 1.08A 3hcrB-5w99A:
undetectable		 3hcrB-5w99A:
undetectable